Thermal epiphysiodesis performed with radio frequency in a porcine model.

Abstract:

BACKGROUND AND PURPOSE:Current techniques for epiphysiodesis involve opening of cortical windows; use of staples, screws, and tension devices; and fusion with curettes or drills. Complications may have serious consequences. There is a need for a more reliable, precise, and less traumatic procedure that overcomes the known complications from existing techniques. We analyzed a new epiphysiodesis technique using radio-frequency ablation (RFA) in a porcine model. METHODS:Six 35-kg and two 25-kg immature pigs were used. 1 hind leg of each animal was randomly selected and the proximal tibia growth plate was ablated laterally and medially. The contralateral leg was used as a control. MR images were obtained immediately after the ablation and 12 weeks later for 6 animals, and 24 weeks later for the other 2 animals. CT was done for the 2 animals that were followed for 24 weeks for proof of bone bridges. RESULTS:Both tibias were equal in length initially. At the 12-week follow-up, there was an average leg length discrepancy of 3.9 mm (95% CI: 3.0-4.8), and at 24 weeks the difference was 8.4 mm and 7.5 mm. No damage to the adjacent tissue was found. Bone bridges and physeal closure were found after 24 weeks. The pigs showed no discomfort after the intervention. INTERPRETATION:We found RFA to be feasible for epiphysiodesis in a pig model. The method is minimally invasive and recovery may be quick compared to conventional methods. We recommend that the method should be tested in larger-scale safety studies before clinical application.

journal_name

Acta Orthop

journal_title

Acta orthopaedica

authors

Shiguetomi-Medina JM,Rahbek O,Abood AA,Stødkilde-Jørgensen H,Møller-Madsen B

doi

10.3109/17453674.2014.939014

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

538-42

issue

5

eissn

1745-3674

issn

1745-3682

journal_volume

85

pub_type

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