Influence of processing by erythrocyte C3b/C4b receptors (CR1) on binding of immune complexes to Raji cells and polymorphonuclear granulocytes.

abstract：:Congenital heart block (CHB) is a conduction abnormality that affects hearts of foetuses and/or newborn to mothers with autoantibodies reactive with the intracellular soluble ribonucleoproteins 48-kD La, 52-kD Ro and 60-kD Ro. CHB carries substantial mortality and morbidity, with more than 60% of affected children req...

journal_title：Scandinavian journal of immunology

authors： Karnabi E,Boutjdir M

更新日期：2010-09-01 00:00:00

abstract：:The enhancement of the lytic capacity of mouse splenic 'natural killer' (NK) cells by interferon has been studied in vitro as a model for NK cell differentiation from inactive immediate precursors. We show that the increased cytotoxicity is a function of interferon concentration, and that two stages in the NK cell dif...

journal_title：Scandinavian journal of immunology

authors： Senik A,Kolb JP,Orn A,Gidlund M

更新日期：1980-01-01 00:00:00

abstract：:Experimental amyloidosis was induced in mice by intraperitoneal injections of endotoxin (lipopolysaccharide (LPS)). In addition to LPS, a group of mice received high-density lipoprotein (HDL)-SAA complexes isolated from human acute-phase serum, whereas a group of control mice received saline in addition to LPS. Isolat...

journal_title：Scandinavian journal of immunology

authors： Husebekk A,Skogen B,Husby G,Marhaug G

更新日期：1985-03-01 00:00:00

abstract：:Saliva was collected from 57 infants aged 6 weeks to 2.5 years and the molecular form of IgA was studied by centrifugation on sucrose density gradients. Two distinct populations were identified. Seventy-two per cent of the children had secretory IgA in their salivary secretions, while 28% had a molecular form correspo...

journal_title：Scandinavian journal of immunology

authors： Cripps AW,Gleeson M,Clancy RL

更新日期：1989-03-01 00:00:00

abstract：:We have investigated the ability of different cells from non-immunized mice of the BALB/c strain to present antigen to two ovalbumin-specific I-Ad-restricted T hybridomas. Lipopolysaccharide-activated B-cell blasts were found to be the most efficient antigen-presenting cells. Purified small and dense splenic B cells a...

journal_title：Scandinavian journal of immunology

authors： Gontijo CM,Möller G

更新日期：1991-08-01 00:00:00

abstract：:The role of Lyt 1+ T-cell-derived secondard CTL inducing factor allowed the cloning of alloreactive cytotoxic T lymphocytes (CTL) by the limiting dilution approach. Several monoclonal cell lines were established in vitro. The lytic activity of some of the cell lines exceeded that of CTL from bulk cultures; that is, 50...

journal_title：Scandinavian journal of immunology

authors： Schawaller R,Röllinghoff M,Wagner H

更新日期：1980-01-01 00:00:00

abstract：:Immunoglobulin D (IgD) is the least studied of immunoglobulin classes. This study sought to investigate the potential relationship between demographic, metabolic, lifestyle and immunological factors, and serum IgD concentrations in a general adult population. We measured serum IgD concentrations by means of a commerci...

journal_title：Scandinavian journal of immunology

authors： Carballo I,Rabuñal N,Alvela L,Pérez LF,Vidal C,Alonso M,Sopeña B,Gude F,Gonzalez-Quintela A

更新日期：2017-04-01 00:00:00

abstract：:Haematopoietic precursors first colonizing the avian embryonic thymus are derived from the intraembryonic sites located around the dorsal aortae. These intraembryonic precursors have previously been demonstrated to include cells that harbour T-cell progenitor capacity and express the Ikaros transcription factor, known...

journal_title：Scandinavian journal of immunology

authors： Liippo J,Koskela K,Lassila O

更新日期：2000-11-01 00:00:00

abstract：:The Kva IgG2(k) myeloma protein showed a complete resistance to papain in the presence of cysteine at neutral pH, and a higher resistance to trypsin and alpha-chymotrypsin digestion than other IgG2 proteins. On the other hand, the Kva molecule was cleaved by pepsin at low pH to give the expected F(ab')2 fragment. When...

journal_title：Scandinavian journal of immunology

authors： Vogt RA,Michaelsen TE

更新日期：1987-07-01 00:00:00

abstract：:Human T lymphocytes, upon phytohaemagglutinin stimulation, are able to form colonies in semisolid media. Peripheral T cell bearing Fc receptors (TG) were studied for their possible regulatory activity on lymphoid colony development. Although no substantial differences were observed between the cloning efficiency of un...

journal_title：Scandinavian journal of immunology

authors： Canonica GW,Pistoia V,Ghio R,Mingari MC,Moretta L

更新日期：1980-01-01 00:00:00

abstract：:The ability of macrophage subpopulations, separated by virtue of differences in size, to liberate soluble factors able to reconstitute antibody and cell-mediated immune responses in macrophage-depleted lymphoid cultures has been investigated. Evidence is presented to show that all macrophages release trypsin- and peps...

journal_title：Scandinavian journal of immunology

authors： Gorczynski RM

更新日期：1977-01-01 00:00:00

abstract：:In a group of 20 patients with asymptomatic paraproteinemia, as judged after at least 3 years of follow-up, the primary and secondary antibody response to Helix pomatia hemocyanin (HPH) was defective as compared with the response in controls. The class of antibody was assessed by mercaptoethanol (ME) treatment of seru...

journal_title：Scandinavian journal of immunology

authors： Weits J,de Gast GC,The TH,Marrink J,Mandema E

更新日期：1976-01-01 00:00:00

abstract：:Physiological ageing is accompanied by decline in immune system function and immune alteration during ageing increases susceptibility to infections. We retrospectively analysed the data for complete blood count (CBC) and lymphocyte subsets from infant to elderly age groups to determine changes during ageing. Data from...

journal_title：Scandinavian journal of immunology

authors： Valiathan R,Ashman M,Asthana D

更新日期：2016-04-01 00:00:00

abstract：:Tumour necrosis factor-α-induced protein-8 like-2 (TIPE2) is a newly identified immune negative regulator. The abnormal expression of TIPE2 has been found in several human inflammatory diseases. However, the expression level and clinical significance of TIPE2 in childhood asthma remain unclear. In this study, we detec...

journal_title：Scandinavian journal of immunology

authors： Ma Y,Liu X,Wei Z,Wang X,Wang Z,Zhong W,Li Y,Zhu F,Guo C,Zhang L,Wang X

更新日期：2013-12-01 00:00:00

abstract：:Patients with juvenile idiopathic arthritis (JIA) have been shown to have elevated levels of circulating immune complexes (CICs) which correlated with disease activity. Our aim was to assess B cell activity by measuring the amount of and the kappa:lambda chain immunoglobulin light (L) chain ratio in CICs from JIA pati...

journal_title：Scandinavian journal of immunology

authors： Low JM,Chauhan AK,Moore TL

更新日期：2007-01-01 00:00:00

abstract：:Screening for B-cell-specific antibodies in unabsorbed pregnancy sera preselected for weak reactivity in regular HLA-A, -B, and -C screening yielded a relatively high proportion (35/81) of B-cell-specific antibodies. Most B-cell-specific antibodies react broadly, showing inclusion phenomena suggesting 'cross-reactivit...

journal_title：Scandinavian journal of immunology

authors： Albert ED,Andreas A,McNicholas A,Scholtz S,Kuntz B

更新日期：1977-01-01 00:00:00

abstract：:Normal human B lymphocytes and Epstein-Barr virus-transformed B-cell lines can produce reactive oxygen species such as superoxide if treated with phorbol myristate acetate (PMA) or with the surface immunoglobulin cross-linking agents protein A and anti-immunoglobulin. Here, we investigated under which conditions speci...

journal_title：Scandinavian journal of immunology

authors： Maly FE,Urwyler A,Tengler R,Steinitz M,Golding B,de Weck AL

更新日期：1990-12-01 00:00:00

abstract：:Basophilic granulocytes and mast cells of different species have been reported to originate from thymocytes and other lymphocytes. These observations were recently confirmed when evidence was given that thymic antigen is present on rabbit basophilic granulocytes. In the study reported here, human leukocytes were teste...

journal_title：Scandinavian journal of immunology

authors： Stallman PJ,Van Elven EH,Feltkamp-Vroom TM,Brutel de la Rivière A

更新日期：1977-01-01 00:00:00

abstract：:Recent studies performed in Seattle, USA have suggested that pretransplant assignment of high or low donor alloreactivity may predict acute graft-versus-host disease (aGvHD) after allogeneic HLA identical marrow transplantation for acute leukaemia. The effect of such pretransplant assignment was studied in a Scandinav...

journal_title：Scandinavian journal of immunology

authors： Johnsen HE,Bostrom L,Moller J,Jorgensen JA,Jensen L,Ringden O

更新日期：1992-03-01 00:00:00

abstract：:Antibodies to DNA (anti-DNA) play an important role in the pathogenesis of systemic lupus erythematosus (SLE). In blood, these antibodies may exist in a free, unbound state or as part of complexes with DNA. Furthermore, circulating DNA may be either complexed or free. Because of the central role of these immunoreactan...

journal_title：Scandinavian journal of immunology

authors： Björkman L,Reich CF,Pisetsky DS

更新日期：2003-06-01 00:00:00

abstract：:Galectin-3 has been suggested as a pro-inflammatory mediator in animal arthritis and rheumatoid arthritis (RA). We aimed to study the serum level of galectin-3 in patients with newly diagnosed RA and associations with disease profile, Magnetic resonance imaging (MRI) findings and seromarkers of synovial matrix inflamm...

journal_title：Scandinavian journal of immunology

authors： Issa SF,Christensen AF,Lindegaard HM,Hetland ML,Hørslev-Petersen K,Stengaard-Pedersen K,Ejbjerg BJ,Lottenburger T,Ellingsen T,Pedersen JK,Junker K,Svendsen A,Tarp U,Østergaard M,Junker P

更新日期：2017-12-01 00:00:00

abstract：:The study of the immunobiology of FVIII inhibitors may lead to new therapies for this potentially severe complication of haemophilia A and to new principles for the use of therapeutic proteins. In order to characterize the idiotype-anti-idiotype networks regulating FVIII inhibitors, we developed rabbit anti-idiotypic ...

journal_title：Scandinavian journal of immunology

authors： Tiarks C,Humphreys RE,Anderson J,Mole J,Pechet L

更新日期：1992-11-01 00:00:00

abstract：:In a well-established murine abortion model, stress is thought to trigger fetal rejection by inducing a proinflammatory immune response via substance P (SP), being tumour necrosis factor (TNF)-alpha-producing CD8+ T cells involved. Interestingly, the SP metabolite SP5-11 also binds to SP receptors and mediates SP-like...

journal_title：Scandinavian journal of immunology

authors： Fest S,Zenclussen AC,Joachim R,Hagen E,Demuth HU,Hoffmann T

更新日期：2006-01-01 00:00:00

abstract：:(NZB x NZW)F1 (B/W) mice spontaneously develop a disease which is remarkably similar to systemic lupus erythematosus (SLE) in humans. This disease is characterized by the appearance of autoantibodies to double-stranded (ds)DNA and the subsequent development of fatal glomerulonephritis. The prophylactic treatment of B/...

journal_title：Scandinavian journal of immunology

authors： Lin RH,Wang LF

更新日期：1994-05-01 00:00:00

abstract：:The aim of this study was to evaluate nocturnal and diurnal urinary melatonin excretion in a group of ischaemic stroke patients, and to verify if a possible impairment of this excretion could be linked with some changes of immunological and neuro-psychic status. We assessed 13 ischaemic stroke patients and five health...

journal_title：Scandinavian journal of immunology

authors： Fiorina P,Lattuada G,Silvestrini C,Ponari O,Dall'Aglio P

更新日期：1999-08-01 00:00:00

abstract：:Bone marrow cells from two patients without detectable monoclonal immunoglobulin (Ig) in serum and urine but with the clinical picture of plasma cell myeloma were cultivated in vitro. Immunofluorescence studies of cultured living and fixed bone marrow cells showed no signs of Ig production in one of the cases, whereas...

journal_title：Scandinavian journal of immunology

authors： Nilsson K,Killander D,Killander J,Mellstedt H

更新日期：1976-01-01 00:00:00

abstract：:In the context of ex vivo T cell elimination from bone marrow, the anti-T cell cytotoxic potential of immunotoxins (IT) prepared by conjugation of the monoclonal antibodies (MoAb) WT32 (CD3), T101 (CD5), and WT1 (CD7) to ricin A chain was evaluated. The cytotoxicity of IT was based on protein synthesis inhibition in h...

journal_title：Scandinavian journal of immunology

authors： Preijers FW,Tax WJ,Wessels JM,Capel PJ,De Witte T,Haanen C

更新日期：1988-05-01 00:00:00

abstract：:The activation of complement and the release of TNF-alpha, IL-6 and IL-8 are important pathogenic factors behind organ dysfunction in sepsis. The aim of this study was to determine whether infusion of anti-TNF antibodies alters complement activation and plasma concentrations of pro-inflammatory cytokines at high doses...

journal_title：Scandinavian journal of immunology

authors： Bengtsson A,Redl H,Schlag G,Högåsen K,Götze O,Mollnes TE

更新日期：1998-11-01 00:00:00

abstract：:The immune system produces specific antibodies (Ab) against any antigens (Ag) of exogenous and endogenous origins with a diverse repertoire of V-region specificities. The primary V-region repertoire is created by the rearrangement of immunoglobulin (Ig) V-region, D- and J-segments with the insertion of N- and P-sequen...

journal_title：Scandinavian journal of immunology

authors： Sakaguchi N,Maeda K,Kuwahara K

更新日期：2011-06-01 00:00:00

abstract：:The trophoblastic tissue and endothelium of fetal stem vessels in cryostat sections of first-trimester and term human placentae adsorbed erythrocytes sensitized with IgG antibodies of human, rabbit, and guinea pig origin. Native and heat-aggregated human and rabbit IgG, and human IgG subclasses except IgG2 inhibited t...

journal_title：Scandinavian journal of immunology

authors： Matre R

更新日期：1977-01-01 00:00:00