Abstract：
BACKGROUND:Rickettsial diseases present as acute febrile illnesses, sometimes with inoculation eschars. METHODS:We performed a systematic review of studies published between 1997 and 2017 to assess the underestimation of non-eschar rickettsial disease (NERD) relative to eschar rickettsial disease (ERD), as a cause of acute fever in patients with rickettsial diseases that commonly present with eschar(s): scrub typhus (ST), Mediterranean spotted fever (MSF), and African tick-bite fever. We compared ERD/NERD ratios according to study design: 'complete approach' studies, with testing performed in all patients with 'unspecified febrile illness'; versus 'clinical judgement' studies, with testing performed if patients presented with specific symptoms. RESULTS:In 'complete approach' studies, ERD/NERD ratios were significantly lower, suggesting a considerable under-diagnosis of NERD in 'clinical judgement' studies. Based on these results, we estimate that the diagnosis of rickettsial disease was missed in 66.5% of patients with ST, and in 57.9% of patients with MSF. CONCLUSIONS:Study design influences the reported eschar rates in ST and MSF significantly. NERD is likely to be a vastly underdiagnosed entity, and clinicians should consider and test for the disease more often. PROSPERO REGISTRATION NUMBER:CRD 42016053348.
journal_name
Travel Med Infect Disjournal_title
Travel medicine and infectious diseaseauthors
van Eekeren LE,de Vries SG,Wagenaar JFP,Spijker R,Grobusch MP,Goorhuis Adoi
10.1016/j.tmaid.2018.02.006subject
Has Abstractpub_date
2018-01-01 00:00:00pages
7-15eissn
1477-8939issn
1873-0442pii
S1477-8939(18)30017-6journal_volume
26pub_type
杂志文章abstract：BACKGROUND:Overuse and misuse of antibiotics have been reported in Hajj. However, little is known about Knowledge, Attitude and Practice (KAP) of pilgrims themselves in relation to these agents. METHODS:Adult pilgrims from seven countries attending the 2015 Hajj were interviewed using a structured KAP questionnaire. ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2018.08.004
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:In an initial study among children from non-Japanese encephalitis (JE)-endemic countries, seroprotection rates remained high 6 months after completion of the primary series with IXIARO®. METHODS:In this open-label follow-up study, a subset of 23 children who received a 2-dose primary series of IXIARO® in th...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2020.101616
更新日期：2020-01-01 00:00:00
abstract：UNLABELLED:Our objective was to determine tuberculin skin test conversion rate of health care workers traveling to Botswana. The rate of tuberculin skin test conversion was 4.2% for the entire group studied or 6.87 per 1000 person weeks (95% CI, 1.87-17.60). BACKGROUND:International travel by health care workers trave...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2013.07.002
更新日期：2014-07-01 00:00:00
abstract：:Schistosomiasis is a common intravascular trematode infection. The snail/human lifecycle is illustrated. Travellers who acquire the infection are often asymptomatic, but nearly always give a history of fresh water exposure in endemic countries when asked. The various manifestations of symptomatic schistosomiasis are d...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2004.02.011
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND:After serious epidemics of chikungunya (CHIKV) and Zika (ZIKV) in the Americas, dengue (DENV) have reemerged in most countries. We analyzed the incidence, incidence rates, and evolution of DENV cases in Honduras from 2015 to 2018 and the ongoing 2019 epidemic. METHODS:Using epidemiological weeks (EW) survei...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2019.101517
更新日期：2019-11-09 00:00:00
abstract：BACKGROUND:Global travellers are increasingly at risk of contracting malaria. The increasing occurrence of drug-resistance in many endemic areas emphasizes the need for novel drug targets for antimalarial-screening. In this study, the use of pyruvate kinase as a drug-target is evaluated. The functional validation of a ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2006.01.015
更新日期：2007-03-01 00:00:00
abstract：:Jet lag is a disorder in which body rhythms are out of phase with the environment because of rapid travel across time zones. Although it often produces minor symptoms it can cause serious problems in those who need to make rapid critical decisions including airline pilots and business travelers. In this article the au...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章,评审
doi：10.1016/j.tmaid.2008.09.004
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:Recently, the number of HIV-infected travellers to (sub)tropical areas has increased substantially. In the Netherlands, HIV-positive travellers with CD4-cells of <500/mm3 are advised to carry stand-by antibiotic treatment against travellers' diarrhoea. Our aim was to determine whether HIV infection is associ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2019.01.003
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:This study assessed the efficacy of education and self-treatment with loperamide on diarrhea morbidity and healthcare utilization in a deployed military setting. METHOD:In this prospective, controlled study, volunteers from military personnel deployed to Incirlik Air Base received either travelers' diarrhea ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2013.12.007
更新日期：2014-07-01 00:00:00
abstract：:Australia has a well-developed tourism industry and health care system. Despite the precautions recommended in this paper, Australia has been virtually free of local outbreaks of life threatening tropical diseases in recent decades. This paper focuses on health and safety issues for travellers to Australia, especially...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/S1477-8939(03)00020-6
更新日期：2003-05-01 00:00:00
abstract：:There are approximately twenty species of hard (ixodid) ticks worldwide that frequently affect human populations, many of which are associated with serious, sometimes fatal disease(s). When a tick travel souvenir is presented in the clinic, the risk must be immediately assessed by identifying the tick in question, asc...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章,评审
doi：10.1016/j.tmaid.2011.01.002
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was first described in 2012 and attracted a great international attention due to multiple healthcare associated outbreaks. The disease carries a high case fatality rate of 34.5%, and there is no internationally or nationally recommended therapy. ME...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2019.06.012
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:The pathogenesis of malaria is the result of complex interactions between parasites, host and environment. Several studies have assessed the role of genetic characteristics of Plasmodium falciparum infection in the clinical severity of malaria infection comparing different genotypic determinants in mild and ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2008.01.001
更新日期：2008-07-01 00:00:00
abstract：:Cutaneous myiasis caused by Dermatobia hominis, the human botfly, involves the infestation of human tissue with fly larvae, and is common in Central and South America. We report a case of a 57-year-old man with cutaneous myiasis imported into the US from Belize. The epidemiology, biological life cycle, clinical presen...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2006.09.005
更新日期：2007-05-01 00:00:00
abstract：:Two Indian migrant workers suffering from fever and malaise were admitted to the hospital directly after arrival in the Netherlands. The first patient was 25-year-old man who had fever and rigors on admission. The patient was treated for presumptive typhoid fever with ciprofloxacin. Cefotaxime was added the following ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2009.06.003
更新日期：2009-09-01 00:00:00
abstract：:A case of typhoidal acalculous cholecystitis is described in a 31-year-old Indian man, who was admitted with 4-day fever, abdominal pain, diarrhea and vomiting. On examination, he looked ill, but was conscious and febrile with icteric sclera. The right upper quadrant of the abdomen was tender. Investigations showed hi...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2009.05.006
更新日期：2009-07-01 00:00:00
abstract：BACKGROUND:On 26 December 2004, the Asian tsunami hit countries around the Indian Ocean rim, particularly around its earthquake-associated epicentre off Indonesia. A number of popular tourist destinations for Australian travellers are located in this region. This study was designed to investigate travel insurance claim...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2006.01.012
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:Estimate inpatient hospitalization costs for patients with microcephaly, and predict cost increases due to a potential Zika virus outbreak. METHODS:We identified Texas-wide inpatient hospitalization discharge records (2008-2015), for newborns and non-newborns with microcephaly. We estimated the cost of each ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2019.01.001
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Due to the condition known as middle ear squeeze, scuba diving has become one of the main causes of barotrauma, and the acute form of this condition has been relatively well established. However, there are few reports available on clinical or laboratory findings in divers who practise repeated diving. The ob...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2004.06.002
更新日期：2005-02-01 00:00:00
abstract：:In scientific discourse, few would consider the widely used term resistance as ambiguous. The definition and usage of the term antimicrobial resistance revolves around the concept that microorganisms change in ways that render antimicrobial medications clinically ineffective. Because artemisinins have become the corne...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2018.04.008
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:The potential for transmission of Mycobacterium tuberculosis during air travel has garnered considerable attention in the media and among public health authorities due to high-profile cases of international travelers with infectious tuberculosis (TB). METHODS:During 2007 and 2008, state and local health off...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2009.08.001
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:We sought to describe travel-related illness among our residents and gain insight into targeting pre-travel health advice to prevent travel-related illness. METHODS:A supplemental travel questionnaire was developed and administered for cases with a legally notifiable communicable disease reported in 2011-20...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2014.05.005
更新日期：2014-09-01 00:00:00
abstract：:Tungiasis is an endemic disease in many resource-poor communities some of which are in South America, which are visited frequently by Spanish travelers. Its diagnosis can be improved with the knowledge of the typical presentation and the correct management of its injuries. We report the first four cases identified of ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2011.03.005
更新日期：2011-05-01 00:00:00
abstract：:International travel is changing the epidemiology of imported malaria. Our aim was to study malaria prophylaxis administered to travellers from Greece. The study was conducted during 2008-2009. Data were collected using a standardized form. A total of 2337 travellers were studied; prophylaxis was recommended to 60.2% ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2011.09.005
更新日期：2011-11-01 00:00:00
abstract：:Many factors are involved in the epidemiology of hemorrhagic fever with renal syndrome (HFRS). Imported cases, as well as those by emigrants, have been reported in literature worldwide. Our goal is to document two cases of HFRS, imported by two immigrants from two countries, and to make a review of the imported HFRS l...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2018.07.010
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:International travel has an important role in transmission of emerging infectious diseases. We described the imported infectious diseases in Korea from 2003 to 2012, and to analyze association of travels with the change in the incidences. METHODS:We used National Notifiable Disease Surveillance System to in...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2017.09.003
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND:Traveller's diarrhoea (TD) is the most common infectious problem for travellers, and we lack effective ways of preventing it, apart from antibiotic prophylaxis. This study aims to quantify the risk reduction of a hypothetic TD vaccine Norwegian travellers are willing to pay for. METHODS:1204 clients at Reis...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2016.10.005
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVES:To assess artemether-lumefantrine effectiveness in the treatment of falciparum malaria in an unsupervised outpatient setting in Africa. DESIGN:Open label prospective study. SETTING:Occupational health clinic, Mozambique. SUBJECTS:Semi-immune Mozambican adults. OUTCOME MEASURES:28-day treatment failures. ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2007.08.007
更新日期：2008-01-01 00:00:00
abstract：:The Global Polio Eradication Initiative (GPEI) in Pakistan has faced failure despite being implemented successfully. Polio cases were successfully reduced by 99% until 2005. However, thereafter, new polio cases were registered, which continue to rise annually. This repeat polio outbreak has placed the country on watch...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章,评审
doi：10.1016/j.tmaid.2015.06.004
更新日期：2015-09-01 00:00:00
abstract：:Air travel during the COVID-19 pandemic is challenging for travellers, airlines, airports, health authorities, and governments. We reviewed multiple aspects of COVID peri-pandemic air travel, including data on traveller numbers, peri-flight prevention, and testing recommendations and in-flight SARS-CoV-2 transmission,...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章,评审
doi：10.1016/j.tmaid.2020.101939
更新日期：2020-01-01 00:00:00
