Effects of pre-deployment loperamide provision on use and travelers' diarrhea outcomes among U.S. military personnel deployed to Turkey.

Abstract:

OBJECTIVE:This study assessed the efficacy of education and self-treatment with loperamide on diarrhea morbidity and healthcare utilization in a deployed military setting. METHOD:In this prospective, controlled study, volunteers from military personnel deployed to Incirlik Air Base received either travelers' diarrhea education (non-loperamide group) or education plus a supply of loperamide (loperamide group). Volunteers were surveyed to determine frequency and outcomes of diarrheal illness. RESULTS:109 deployed personnel were enrolled with 48 assigned to the loperamide group, and 61 to the non-loperamide group. Overall, 41 (38%) service members had at least one diarrheal episode. Only 10 (9%) service members sought treatment from a healthcare provider and the distribution was similar in both groups. Loperamide use for self-treatment was more common in the loperamide group (85%) vs. (57%), [p = 0.02]) but use of antibiotics was similar in both groups (loperamide (30%) vs. non-loperamide (20%). CONCLUSIONS:Provision of loperamide and education did not significantly affect healthcare utilization or antibiotic use to manage diarrheal episodes, when compared to education alone. Further prospective studies will either need a very large patient population to power them or should use other primary end points such a functional assessment in addition to seeking care.

journal_name

Travel Med Infect Dis

authors

Letizia A,Riddle MS,Tribble D,Mostafa M,Monteville M,Armstrong A,Gutierrez RL

doi

10.1016/j.tmaid.2013.12.007

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

360-3

issue

4

eissn

1477-8939

issn

1873-0442

pii

S1477-8939(14)00003-9

journal_volume

12

pub_type

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