Abstract：
OBJECTIVE:Estimate inpatient hospitalization costs for patients with microcephaly, and predict cost increases due to a potential Zika virus outbreak. METHODS:We identified Texas-wide inpatient hospitalization discharge records (2008-2015), for newborns and non-newborns with microcephaly. We estimated the cost of each hospitalization by applying cost-to-charge ratios on the actual hospitalization charge. For comparison, newborn visits for patients without microcephaly were also identified, and hospital costs were compared between patients with and without microcephaly. We estimated costs for microcephaly during the first year of life following a Zika outbreak (possible 1-50% increase in birth prevalence) in Texas. RESULTS:There were 8005 microcephaly hospitalizations ($203,899,042; total cost). The median admission cost for newborns with microcephaly (N = 1393) was higher compared to those without microcephaly ($6751 vs $725, p < 0.001). Microcephaly hospitalizations of newborns had a lower median cost compared to non-newborns ($6751 vs $9754, p < 0.001). Based on these observed hospitalization costs, we estimated that a potential Zika virus outbreak in Texas could result in an additional $1-6 million per year for hospitalizations. CONCLUSION:Hospitalizations of patients with microcephaly are associated with high costs. An increase in microcephaly prevalence due to a Zika outbreak in Texas could have a considerable impact on health care costs.
journal_name
Travel Med Infect Disjournal_title
Travel medicine and infectious diseaseauthors
Shewale JB,Ganduglia Cazaban CM,Waller DK,Mitchell LE,Langlois PH,Agopian AJdoi
10.1016/j.tmaid.2019.01.001subject
Has Abstractpub_date
2019-01-01 00:00:00pages
67-72eissn
1477-8939issn
1873-0442pii
S1477-8939(19)30001-8journal_volume
30pub_type
杂志文章abstract：BACKGROUND:The potential for transmission of Mycobacterium tuberculosis during air travel has garnered considerable attention in the media and among public health authorities due to high-profile cases of international travelers with infectious tuberculosis (TB). METHODS:During 2007 and 2008, state and local health off...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2009.08.001
更新日期：2010-03-01 00:00:00
abstract：:The risk of infection with hepatitis E virus to international travellers to endemic regions such as the subcontinent of India, Nepal, South-East Asia, China, parts of the Middle East, Africa, Mexico and some countries of South America is underestimated. Hepatitis E virus is transmitted enterically usually by drinking ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/S1477-8939(03)00039-5
更新日期：2003-05-01 00:00:00
abstract：UNLABELLED:Our objective was to determine tuberculin skin test conversion rate of health care workers traveling to Botswana. The rate of tuberculin skin test conversion was 4.2% for the entire group studied or 6.87 per 1000 person weeks (95% CI, 1.87-17.60). BACKGROUND:International travel by health care workers trave...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2013.07.002
更新日期：2014-07-01 00:00:00
abstract：:Tungiasis is a parasitic skin disease caused by the penetration of female sand fleas (Tunga penetrans). It is acquired when people walk barefoot or rest on soil, where sand fleas have completed the off-host cycle. Tungiasis is a classic poverty-associated disease which belongs to the family of neglected tropical disea...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章,评审
doi：10.1016/j.tmaid.2013.10.001
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Increasing numbers of sporadic cases of melioidosis in returning travelers have been reported from non-endemic regions. METHODS:We report a new case and undertook a literature review. RESULTS:Eighty-two travelers with melioidosis infection were included. The mean age was 50.95 years, with only one case <15...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章,评审
doi：10.1016/j.tmaid.2015.08.007
更新日期：2015-09-01 00:00:00
abstract：:Since November 2006, flight-related mumps contact investigations were conducted in the United States only for flights ≥5 h long after an investigation showed minimal risk of mumps transmission on flights <5 h. Because the transmission risk on longer flights had not been evaluated, we investigated whether there was evi...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2012.06.003
更新日期：2012-07-01 00:00:00
abstract：BACKGROUND:From the first Zika virus (ZIKV) description, it has progressively widespread worldwide. We analyzed demographic, clinical, microbiologic and travel-related characteristic from returned patients from a ZIKV endemic country in a referral Tropical Medicine Unit. METHOD:A prospective cohort study performed in ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2019.101543
更新日期：2020-01-01 00:00:00
abstract：:The prevalence of Toscana virus (TOSV) IgG antibodies was determined among 128 residents of two Greek islands in the Ionian Sea, Corfu and Cephalonia. In total, 47.7% of tested persons had TOSV IgG antibodies; 51.7% among residents of Corfu and 39% among residents of Cephalonia. The prevalence was higher among persons...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2010.09.002
更新日期：2010-09-01 00:00:00
abstract：:The number of travellers returning with animal bites from rabies enzootic areas has increased in Greece. The aim of this study was to assess the knowledge of travel-associated risk and preventive measures for rabies. A questionnaire was sent to Travel Medicine consultants in all prefectures. Of 100 Travel Medicine con...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2010.11.004
更新日期：2011-01-01 00:00:00
abstract：:Infection with Plasmodium ovale is uncommon in travelers. We describe a case of ovale malaria in a traveler to Mozambique who initially presented several weeks after completion of his trip. Species identification was ultimately achieved with a PCR-based diagnostic method. ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2007.02.003
更新日期：2007-07-01 00:00:00
abstract：:Tungiasis is an endemic disease in many resource-poor communities some of which are in South America, which are visited frequently by Spanish travelers. Its diagnosis can be improved with the knowledge of the typical presentation and the correct management of its injuries. We report the first four cases identified of ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2011.03.005
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:International travel is a risk factor for colonization with Extended-Spectrum Beta-Lactamase-producing- Enterobacteriaceae (ESBL-E). We describe the prevalence of and risk-factors for ESBL-E colonization in civilian and military travelers. METHODS:Patients hospitalized in the infectious diseases department ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2018.03.009
更新日期：2018-01-01 00:00:00
abstract：:Background. The Roll Back Malaria (RBM) initiative has committed itself to halving the worlds's malaria burden by 2010, having adopted five operationally focused 'critical concepts' to guide this task. The focus of RBM's efforts is in the developing world where external support is often required. Malaria was only rece...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2003.09.004
更新日期：2003-08-01 00:00:00
abstract：BACKGROUND:In 2018, tafenoquine was approved for malaria chemoprophylaxis. We evaluated all available data on the safety and efficacy of tafenoquine chemoprophylaxis. METHODS:This systematic review followed the PRISMA guidelines and was registered on PROSPERO (CRD42019123839). We searched PubMed, Embase, Scopus, CINAH...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2020.101908
更新日期：2020-11-20 00:00:00
abstract：:Sexually transmitted infections are often acquired during travel. Infections are most often seen in young adults, travelling without a regular partner and among those who have higher numbers of partners while at home. Alcohol and recreational drug use may increase risk. The risks are highest from having unprotected se...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章,评审
doi：10.1016/j.tmaid.2005.06.010
更新日期：2006-05-01 00:00:00
abstract：:Recent case reports of viral hemorrhagic fever in Europe and the United States have raised concerns about the possibility for increased importation of filoviruses to non-endemic areas. This emerging threat is concerning because of the increase in global air travel and the rise of tourism in central and eastern Africa ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2010.05.003
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:Most approved medicines, including vaccines can be associated with adverse events. A vaccine adverse event is defined as any untoward medical occurrence which follows vaccination, but which does not necessarily have a causal relationship with the administration of the vaccine. METHODS:The objective of this ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章,评审
doi：10.1016/j.tmaid.2014.01.008
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:We aimed to identify socio-demographic, or illness-specific variables, influencing travel behaviour of haemophilic patients. METHODS:A standardised questionnaire was sent to more than 2000 members of two German Haemophilia associations. Multivariable logistic regression with the outcomes frequent (at least ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2013.03.008
更新日期：2013-05-01 00:00:00
abstract：:International travel is changing the epidemiology of imported malaria. Our aim was to study malaria prophylaxis administered to travellers from Greece. The study was conducted during 2008-2009. Data were collected using a standardized form. A total of 2337 travellers were studied; prophylaxis was recommended to 60.2% ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2011.09.005
更新日期：2011-11-01 00:00:00
abstract：INTRODUCTION:Middle East Respiratory Coronavirus Virus (MERS-CoV) first emerged from Saudi Arabia in 2012 and has since been recognized as a significant human respiratory pathogen on a global level. METHODS:In this narrative review, we focus on the prevention of MERS-CoV. We searched PubMed, Embase, Cochrane, Scopus, ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章,评审
doi：10.1016/j.tmaid.2019.101520
更新日期：2019-11-12 00:00:00
abstract：BACKGROUND:Travellers are confronted with a variety of vector-borne threats. Is one type of repellent effective against all biting vectors? The aim of this review is to examine the literature, up to December 31st, 2012, regarding repellent efficacy. METHODS:We searched PubMed for relevant papers. Repellents of interes...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章,评审
doi：10.1016/j.tmaid.2013.10.005
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:The number of adolescents who travel has increased. We estimated the preparedness of adolescents (12-18 years) departing from Athens to Africa and Asia. METHODS:An airport-based survey was conducted from 2011 to 2015. RESULTS:Sixty-eight adolescents participated; 27/68 (40%) had the Greek nationality. Thei...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2017.07.011
更新日期：2018-01-01 00:00:00
abstract：:A case of typhoidal acalculous cholecystitis is described in a 31-year-old Indian man, who was admitted with 4-day fever, abdominal pain, diarrhea and vomiting. On examination, he looked ill, but was conscious and febrile with icteric sclera. The right upper quadrant of the abdomen was tender. Investigations showed hi...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2009.05.006
更新日期：2009-07-01 00:00:00
abstract：:A case is described of subcutaneous dirofilariasis in a Greek woman who had visited many countries around the world, including areas of sub-Saharan Africa. The patient presented with a single hard subcutaneous nodule on the right cheek, with no cutaneous manifestations of early or long-standing onchocercal dermatitis ...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2009.05.001
更新日期：2009-09-01 00:00:00
abstract：INTRODUCTION:Among deployed U.S. military personnel, a sub-population of international travelers, acute infectious diarrhea continues to be a leading cause of morbidity and a potential threat to military effectiveness. METHODS:To assess outcomes and satisfaction of diarrhea management in the field, a systematic survey...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2009.09.001
更新日期：2009-11-01 00:00:00
abstract：:Malaria is among the most significant travel-related infections encountered by travellers to endemic countries in terms of morbidity and mortality. The aim of this study is to assess the knowledge and practices about malaria prophylaxis of travel medicine consultants in Greece. A standardized questionnaire was sent to...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2012.09.006
更新日期：2012-09-01 00:00:00
abstract：BACKGROUND:Currently, Brazil is experiencing one of the fastest increasing coronavirus disease (COVID-19) mortality rates worldwide, with a minimum of 158,000 confirmed deaths presently. The city of São Paulo is particularly vulnerable because it is the most populated city in Brazil. Thus, this study aimed to analyse C...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2020.101945
更新日期：2020-12-02 00:00:00
abstract：BACKGROUND:The diagnosis of acute malaria in non-endemic countries is still carried out largely by microscopic examination of thick and thin smears or rapid diagnostic tests. Low-density infections might be missed, however, but the more sensitive PCR is more expensive, complex and requires considerable more time. METH...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2014.12.016
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Civil air travel is increasingly recognized as an important potential source for the rapid spread of infectious diseases that were geographically confined in the past, creating international epidemics with great health and socio-economic impact. OBJECTIVE:The objective of this systematic review is to elucid...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2018.07.011
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:In an initial study among children from non-Japanese encephalitis (JE)-endemic countries, seroprotection rates remained high 6 months after completion of the primary series with IXIARO®. METHODS:In this open-label follow-up study, a subset of 23 children who received a 2-dose primary series of IXIARO® in th...
journal_title：Travel medicine and infectious disease
pub_type： 杂志文章
doi：10.1016/j.tmaid.2020.101616
更新日期：2020-01-01 00:00:00
