Lactobacillus crispatus represses vaginolysin expression by BV associated Gardnerella vaginalis and reduces cell cytotoxicity.

Abstract:

:Using a chemically-defined medium simulating genital tract secretions, we have shown that pre-adhering Lactobacillus crispatus to Hela epithelial cells reduced cytotoxicity caused by Gardnerella vaginalis. This effect was associated to the expression of vaginolysin and was specific to L. crispatus interference, as other vaginal facultative anaerobes had no protective effect.

journal_name

Anaerobe

journal_title

Anaerobe

authors

Castro J,Martins AP,Rodrigues ME,Cerca N

doi

10.1016/j.anaerobe.2018.01.014

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

60-63

eissn

1075-9964

issn

1095-8274

pii

S1075-9964(18)30027-1

journal_volume

50

pub_type

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