Abstract:
:Tuberculosis (TB) is a poverty infectious disease that affects millions of people worldwide. Evidences suggest that social protection strategies (SPS) can improve TB treatment outcomes. This study aimed to synthesize such evidences through systematic literature review and meta-analysis. We searched for studies conducted in low- or middle-income and in high TB-burden countries, published during 1995-2016. The review was performed by searching PubMed/MEDLINE, Scopus, Web of Science, ScienceDirect and LILACS. We included only studies that investigated the effects of SPS on TB treatment outcomes. We retained 25 studies for qualitative synthesis. Meta-analyses were performed with 9 randomized controlled trials, including a total of 1,687 participants. Pooled results showed that SPS was associated with TB treatment success (RR = 1.09; 95%CI: 1.03-1.14), cure of TB patients (RR = 1.11; 95%CI: 1.01-1.22) and with reduction in risk of TB treatment default (RR = 0.63; 95%CI: 0.45-0.89). We did not detect effects of SPS on the outcomes treatment failure and death. These findings revealed that SPS might improve TB treatment outcomes in lower-middle-income economies or countries with high burden of this disease. However, the overall quality of evidences regarding these effect estimates is low and further well-conducted randomized studies are needed.
journal_name
Cad Saude Publicajournal_title
Cadernos de saude publicaauthors
Andrade KVF,Nery JS,Souza RA,Pereira SMdoi
10.1590/0102-311X00153116subject
Has Abstractpub_date
2018-02-05 00:00:00pages
e00153116issue
1eissn
0102-311Xissn
1678-4464pii
S0102-311X2018000102001journal_volume
34pub_type
杂志文章,meta分析,评审abstract::Diarrhea is an important cause of hospitalization among infants. There are many complex factors that influence hospital use: socioeconomic and cultural characteristics, access, medical needs, and supply. The objective was to measure hospitalization rates from diarrhea among infants in Rio de Janeiro in 1996 and the as...
journal_title:Cadernos de saude publica
pub_type: 杂志文章
doi:
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
pub_type: 杂志文章
doi:10.1590/s0102-311x2006000700015
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journal_title:Cadernos de saude publica
pub_type: 杂志文章
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
pub_type: 杂志文章
doi:10.1590/s0102-311x2010000400022
更新日期:2010-04-01 00:00:00
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journal_title:Cadernos de saude publica
pub_type: 杂志文章
doi:10.1590/0102-311X00002120
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journal_title:Cadernos de saude publica
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Cadernos de saude publica
pub_type: 杂志文章
doi:10.1590/s0102-311x2010000900013
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journal_title:Cadernos de saude publica
pub_type: 杂志文章
doi:10.1590/s0102-311x2006001000014
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journal_title:Cadernos de saude publica
pub_type: 杂志文章
doi:10.1590/s0102-311x2003000100023
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pub_type: 杂志文章
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journal_title:Cadernos de saude publica
pub_type: 杂志文章
doi:10.1590/s0102-311x2010000800015
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journal_title:Cadernos de saude publica
pub_type: 杂志文章,评审
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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journal_title:Cadernos de saude publica
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