Abstract：
:Sickle cell nephropathy is a major complication of sickle cell disease. It manifests in different forms, including glomerulopathy, proteinuria, hematuria, and tubular defects, and frequently results in end-stage renal disease (ESRD). Different pathophysiologic mechanisms have been proposed to explain the development of nephropathy in SCD, where hemolysis and vascular occlusion are the main contributors in the manifestations of this disease. Markers of renal injury, such as proteinuria and tubular dysfunction, have been associated with outcomes among patients with sickle cell nephropathy and provide means for early detection of nephropathy and screening prior to progression to renal failure. In small-sized clinical trials, hydroxyurea has demonstrated to be effective in slowing the progression to ESRD. Dialysis and renal transplantation represent the last resort for patients with sickle cell nephropathy. Nevertheless, despite the availability of diagnostic and therapeutic strategies, sickle cell nephropathy remains a challenging and under-recognized complication for patients with sickle cell disease.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Hariri E,Mansour A,El Alam A,Daaboul Y,Korjian S,Aoun Bahous Sdoi
10.1007/s11255-018-1803-3subject
Has Abstractpub_date
2018-06-01 00:00:00pages
1075-1083issue
6eissn
0301-1623issn
1573-2584pii
10.1007/s11255-018-1803-3journal_volume
50pub_type
杂志文章,评审abstract：OBJECTIVES:To study the impact of radical tumour surgery in prostate and renal cell cancer patients on quality of life (QOL). METHODS:In 38 male patients suffering from organ-confined prostate or renal cell cancer, a prospective study was performed. For the evaluation of QOL, we used the EMPK (Erfassung multipler psyc...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02552179
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:We aimed to evaluate the efficacy of Lachance formula and more readily available clinical or laboratory factors (other than serum methanol level) in prediction of the needed time for hemodialysis in methanol-poisoned patients. METHODS:In a retrospective study, all methanol-poisoned patients referred to us betw...
journal_title：International urology and nephrology
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abstract：:Analysis was performed on the clinical features of children with VUR who had one or two kidneys that were at least -2 SD smaller than normal for age of its renal ratio. The prevalence of the small kidney was 15.6% (97/623 children). Of 107 small kidneys, 87 (82%) were associated with moderate (grade IV) to severe (gra...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02549509
更新日期：1988-01-01 00:00:00
abstract：:The major cause of death among chronic kidney disease patients is cardiovascular diseases. Cardiovascular and kidney disease are interrelated and increase the severity of each other. Dyslipidemia is one the major causes of cardiovascular disease among chronic kidney disease patients along with diabetes and hypertensio...
journal_title：International urology and nephrology
pub_type： 杂志文章,评审
doi：10.1007/s11255-018-2047-y
更新日期：2019-02-01 00:00:00
abstract：:Peripheral PRA was examined in 11 patients with graft artery stenosis after the onset and throughout the course of hypertension. In the acute stage PRA was elevated in 9 patients and decreased to normal in the later stage of hypertension in all but 1 patient with malignant hypertension. The findings suggest that the d...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02082428
更新日期：1981-01-01 00:00:00
abstract：:We report an unusual case of benign recurrent pheochromocytoma that developed at the same site 8 years following initial treatment. This tumor was managed successfully through the 11th rib bed using the transperitoneal extrapleural approach. ...
journal_title：International urology and nephrology
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abstract：:We report a case of renal cell carcinoma with solitary metastasis to the bladder which occurred and was treated synchronously. The mode of spread and possible treatment modalities are discussed with relevant information from the literature. ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02767654
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:In large observational studies of adult kidney transplant recipients (KTRs) where older adults (65 years old and older) were not well represented, the mammalian target of rapamycin inhibitors (mTOR inhibitors) has poorer outcomes than the standard tacrolimus-mycophenolate-steroids (TAC-MPA-S) regimen. We conduc...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-019-02251-w
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:The present study aimed to evaluate the impact of a filmed research-based drama-Fit for Dialysis-and an exercise program on patients' physical activity and fitness outcomes. METHODS:Nineteen (10 at the intervention site, 9 at the control site) older patients with a medical diagnosis of hemodialysis-dependent e...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-020-02745-y
更新日期：2021-01-02 00:00:00
abstract：PURPOSE:The purpose of the study was to assess safety and efficacy of autologous muscle derived cells for urinary sphincter repair (AMDC-USR) in female subjects with predominant stress urinary incontinence. METHODS:A randomized, double-blind, multicenter trial examined intra-sphincteric injection of 150 × 106 AMDC-USR...
journal_title：International urology and nephrology
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2018-12-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-020-02473-3
更新日期：2020-06-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-017-1678-8
更新日期：2017-11-01 00:00:00
abstract：:Chronic hepatic patients, and particularly those suffering from cirrhosis, are predisposed to different sort of water, electrolyte, acid-base, and trace elements disorders due to their altered liver function, and also to their exposition to infectious, inflammatory, oncologic, and pharmacologic variables whose combina...
journal_title：International urology and nephrology
pub_type： 杂志文章,评审
doi：10.1007/s11255-017-1614-y
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:The authors observed priapism as a side effect occuring during the intracavernous treatment of erectile dysfunction. Earlier priapism had been treated with an intracavernous injection of sympatomimetics; unfortunately several complications and contraindications were found. PATIENTS AND METHODS:Methylene blue...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1023/b:urol.0000025617.97048.ae
更新日期：2003-01-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02217144
更新日期：1980-01-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-019-02305-z
更新日期：2020-02-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-014-0826-7
更新日期：2014-12-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02550317
更新日期：1998-01-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章,评审
doi：10.1007/s11255-013-0505-0
更新日期：2013-12-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章,评审
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-018-1821-1
更新日期：2018-05-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章,评审
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更新日期：2014-01-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s11255-018-1973-z
更新日期：2018-11-01 00:00:00
abstract：:A prospective study of plasma luteinizing hormone (LH) and follicle stimulating hormone (FSH) in 51 men before vasectomy and 10 days and 3 months after vasectomy revealed a trend to rise in LH 10 days after vasectomy normalizing after 3 months. The literature concerning alterations in LH and FSH after vasectomy is rev...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02549744
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abstract：:A rare case of benign pelvic neurilemmoma with bladder infiltration and ureteral obstruction is presented. This neurally originated tumor may occur anywhere in the body, but involvement of the urinary tract is rare. Management depends upon location and other clinical findings, and in this case, since complete removal ...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02082366
更新日期：1978-01-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-013-0412-4
更新日期：2013-06-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/BF02559638
更新日期：1989-01-01 00:00:00
abstract：PURPOSE:To investigate whether an elevated serum uric acid (SUA) level is an independent risk factor for rapid decline in renal function or new-onset chronic kidney disease (CKD) in a Chinese health checkup population. METHODS:A cohort study of 6495 Chinese individuals who underwent health checkups with normal estimat...
journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-017-1732-6
更新日期：2018-03-01 00:00:00
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journal_title：International urology and nephrology
pub_type： 杂志文章
doi：10.1007/s11255-007-9206-x
更新日期：2007-01-01 00:00:00
abstract：:This is the first prospective study to investigate the association between kidney stones, bone mineral density, serum testosterone, colon cancer and O. formigenes colonization. 40 kidney stone patients and 85 controls were enrolled. O. formigenes colonization was established. BMD was examined from T- and Z-scores usin...
journal_title：International urology and nephrology
pub_type： 杂志文章
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更新日期：2021-01-01 00:00:00
