Abstract:
AIM:The aim of the present study was to determine whether administration of zolpidem, a nonbenzodiazepine sedative-hypnotic agent, at night would improve the frequency of nocturia unresponsive to alpha-blocker monotherapy in men with lower urinary tract symptoms (LUTS). MATERIALS AND METHODS:The study inclusion criteria were: age >/=50 years, nocturia twice or more per night (International Prostate Symptom Score [IPSS] question 7) after taking alpha-blockers for more than eight weeks, and incomplete frequency-flow chart (FVC). A total of 18 patients met the criteria and constituted the study cohort. Three patients were given 0.2 mg tamsulosin once daily and others were given 4 mg terazosin once daily. All patients were additionally administered 10 mg zolpidem once at night for the eight weeks. RESULTS:There were no serious side-effects in any patient. Nocturia decreased from a baseline median (25-75th percentiles) of 3 (3-5) to 3 (3-4.5) episodes after taking alpha-blockers (p = 0.129) and to 2 (1-3) episodes after taking zolpidem and alpha-blockers (p = 0.001) on the IPSS. After treatment, the scores of uroflowmetry values did not significantly changed. However, at eight weeks, voiding symptoms (p = 0.041) and total IPSS scores (p = 0.028) significantly decreased compared with those at baseline. Median (25-75th percentiles) quality-of-life (QoL) index changed from 5 (4-5) at baseline to 3 (3-3) after eight weeks of treatment (p = 0.005). CONCLUSION:Our results indicate that zolpidem resulted in a subjective reduction in nocturia episodes when given to some men with LUTS.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Song YS,Ku JHdoi
10.1007/s11255-007-9206-xsubject
Has Abstractpub_date
2007-01-01 00:00:00pages
1147-52issue
4eissn
0301-1623issn
1573-2584journal_volume
39pub_type
杂志文章abstract:PURPOSE:A region of chromosome 22 which includes APOL1 and MYH9 genes was recently identified as a risk locus for non-diabetic forms of kidney disease, including idiopathic and HIV-associated focal segmental glomerular sclerosis and kidney disease clinically attributed to hypertension among African Americans. The purpo...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-012-0263-4
更新日期:2013-04-01 00:00:00
abstract::A case of Itai-itai (ouch-ouch) disease with reduced urinary kallikrein excretion and slightly enhanced renin-angiotensin-aldosterone system is described. Although it is well known that cadmium toxicity frequently affects the renal tubular lesions, this report is the first to demonstrate the impaired urine concentrati...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550809
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:To evaluate conservative management of renal echinococcosis in cases with normal renal function and active disease. PATIENTS AND METHODS:From a series of 12 consecutive patients with primary renal echinococcosis, nephrectomy was suggested to 4 patients because of kidney destruction. One patient who denied surg...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1014405325703
更新日期:2001-01-01 00:00:00
abstract::The vesical stone formation due to intravesical mesh erosion of tension-free vaginal tape (TVT) is rare. In this report, a case of 48-year-old patient who underwent (TVT) elsewhere is discussed. The patient was presented with vesical stone and persistent stress urinary incontinence. Intravesical stone was detected by ...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-006-9080-y
更新日期:2007-01-01 00:00:00
abstract::Genitourinary organs are at greater risk for multiple primary malignant neoplasms because of the high incidence of these tumours as primaries among all other organs. We present a case of prostate and bladder carcinoma metastasized to a single pelvic lymph node, called a "collision" metastasis, in a patient with four p...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02552140
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To compare the economic burden and cost-utility analysis of the renal replacement therapies, including hemodialysis (HD), peritoneal dialysis (PD), and allograft kidney transplantation (KT) among end-stage renal disease (ESRD) patients from Yunnan Province, China. METHODS:Multistage stratified random sampling ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02394-1
更新日期:2020-03-01 00:00:00
abstract::Fifteen patients with urinary retention following rectal resection were examined urodynamically, including cystometry and simultaneous measurement of flow and pressure in the bladder and in the abdomen. Five patients suffered from bladder neck obstruction. This was in most cases put down to a preexisting prostatic enl...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02081813
更新日期:1982-01-01 00:00:00
abstract::Between 1985 and 1989, 54 boys underwent a MAGPI procedure. Excellent cosmetic and functional results were achieved in 94% of our cases in the early period. In order to assess the long-term results of this procedure, 41 boys attended long-term re-evaluation between 6 and 40 (mean 29) months postoperatively. MAGPI was ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549850
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:ADPKD is one of the most common inherited disorders, with high risk for end-stage renal disease. Numerous patients, however, have no relatives in whom this disorder is known and are unsure whether they may transmit the disease to their offsprings. The aim of this study was to evaluate whether germline mutati...
journal_title:International urology and nephrology
pub_type: 杂志文章
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更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:The prevalence of progressive chronic kidney disease (CKD) in children and adults with spina bifida is considerable, rising, and entirely preventable. REMOVING THE CAUSE:PREVENTION OF SPINA BIFIDA: The best prevention of CKD in spina bifida is prevention of spina bifida itself throug...
journal_title:International urology and nephrology
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abstract:OBJECTIVES:To evaluate the treatment alternatives of total avulsion of the ureter from both ends including ureteropelvic junction (UPJ) and ureterovesical junction (UVJ). METHODS:Total ureteral avulsion on both ends of the ureter was examined in 4 cases performing ureteroscopy. In two male patients of the four cases, ...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
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更新日期:2013-12-01 00:00:00
abstract:AIMS:Sacral neurostimulation (SNS) involves a two-stage procedure to assess outcomes prior to permanent implantation. Stage 1 involves placement of a sacral lead that is externalized and tested for 2 weeks. Stage 2 is the implantation of a pulse generator in responders (≥ 50% improved). This study's purpose was to dete...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-9919-8
更新日期:2011-12-01 00:00:00
abstract::A new method of one-stage surgical correction of distal to penoscrotal hypospadias is described. The chordee is released by skin lysis alone and urethroplasty is done by the flip-flap technique while the globular glans is rerolled over the new urethra, all in one stage. The complication rate was minimal (15 per cent),...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082566
更新日期:1984-01-01 00:00:00
abstract::Authors describe and discuss cases of massive haemorrhage after percutaneous nephrolithotomy. In 10 (0.3%) of 3080 patients who underwent PCNL massive haemorrhage from renal fistula drain or urinary bladder was observed. Renal arteriography was performed in this group of patients which revealed arteriovenous fistulae ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550492
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Chronic kidney disease (CKD) is a worldwide health problem, and promotion of the World Kidney Day has improved general population education and awareness of renal illnesses aimed at ameliorating disease prevention. The Kidney Day was also an opportunity for us to investigate risk factors for CKD in an Italia...
journal_title:International urology and nephrology
pub_type: 杂志文章
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更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To evaluate the results of plaque incision and venous patch grafting to correct the dorsal curvature associated with Peyronie's disease. MATERIALS AND METHODS:18 patients with Peyronie's disease were treated surgically. All of the patients have dorsal penile curvature for more than one year causing intromissio...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1023290705439
更新日期:2002-01-01 00:00:00
abstract::Serum concentrations of luteinizing hormone (LH), testosterone, prostatic acid phosphatase (PAP) and prostatic specific antigen (PSA) were measured in 16 patients with advanced prostatic cancer before and after treatment with luteinizing hormone-releasing hormone (LHRH) analogue. An initial rise of serum LH and testos...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02564863
更新日期:1998-01-01 00:00:00
abstract::Persistent Mullerian duct syndrome (PMDS) is a rare form of the 46 XY disorders of sexual differentiation, characterized by the presence of a uterus and fallopian tubes due to the failure of Mullerian duct regression in genotypically normal males. More than 150 cases have been recorded, most of them in adults. In most...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-014-0667-4
更新日期:2014-08-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章
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更新日期:2014-06-01 00:00:00
abstract::We aimed to investigate whether high peripheral and cavernosal plasma levels of apolipoprotein-(a) [Lp (a)] is an indicator for vasculogenic erectile dysfunction. We determined Lp (a), total cholesterol (TC), triglyceride (TG) and high density lipoprotein (HDL) levels in peripheral and cavernosal blood in 39 patients ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550575
更新日期:1998-01-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章,meta分析,评审
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更新日期:2017-01-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 社论
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更新日期:2016-05-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02559638
更新日期:1989-01-01 00:00:00
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journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082069
更新日期:1981-01-01 00:00:00
abstract:PURPOSE:To investigate the effect of intradialytic resistance exercise on inflammation markers and sarcopenia indices in maintenance hemodialysis (MHD) patients with sarcopenia. METHODS:Forty-one MHD patients with sarcopenia were divided into an intervention group (group E, n = 21) and a control group (group C, n = 20...
journal_title:International urology and nephrology
pub_type: 杂志文章,随机对照试验
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更新日期:2019-08-01 00:00:00
abstract::A 40-year-old man was referred to our hospital with gynecomastia and painless swelling of the right scrotum. Ultrasonography revealed a 15 x 10 mm mass with low echogenicity of the right testis. We performed right high orchiectomy. Histologically, Reinke's crystals and capsular invasion by tumor cells were found. Fina...
journal_title:International urology and nephrology
pub_type: 杂志文章
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abstract::To remove multiple calyceal stones percutaneously is not a simple task. During the act of dilating the pierced channel the stones are apt to drift away towards other parts of the renal cavitary system. For avoidance we recommend the use of Pyeloform, a bicomponent synthetic compound in which chemical reaction between ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:Sodium restriction is important for the management of chronic kidney disease (CKD). The present study evaluated the factors impacting dietary sodium restriction in a cohort of Chinese patients with CKD. METHODS:A questionnaire on dietary sodium restriction was administered to patients with non-dialysis CKD who...
journal_title:International urology and nephrology
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abstract::Neurofibromatosis of the urinary tract is estimated to account for 20 per cent of the visceral manifestations of the generalized disease. Among its urological forms involvement of the bladder is the most common. Clinically, neurofibromatosis resembles a tumour, therefore, its early histologic diagnosis is of utmost im...
journal_title:International urology and nephrology
pub_type: 杂志文章
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更新日期:1985-01-01 00:00:00
abstract::The activity of the leucocyte inhibitory factor (LIF) stimulated with Concanavalin A was examined in chronic uraemic, haemodialysed patients. It was found that the LIF activity decreased in chronic uraemic patients as compared with the normal controls. The absolute T lymphocyte count and active E rosette formation als...
journal_title:International urology and nephrology
pub_type: 杂志文章
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更新日期:1980-01-01 00:00:00