Influence of luteinizing hormone-releasing hormone analogues on serum levels of prostatic acid phosphatase and prostatic specific antigen in patients with metastatic carcinoma of the prostate.

Abstract:

:Serum concentrations of luteinizing hormone (LH), testosterone, prostatic acid phosphatase (PAP) and prostatic specific antigen (PSA) were measured in 16 patients with advanced prostatic cancer before and after treatment with luteinizing hormone-releasing hormone (LHRH) analogue. An initial rise of serum LH and testosterone levels was observed on day 2 of the treatment. Subsequently, serum concentrations of PAP and PSA showed a transient increase on day 5 of the treatment. This indicates that LHRH analogues had better be given in combination with antiandrogens in patients with metastatic carcinoma of the prostate.

journal_name

Int Urol Nephrol

authors

Sasagawa I,Kubota Y,Nakada T,Suzuki H,Hirano J,Sugano O,Kato H,Imamura A,Mastushita K,Onmura Y,Saito M,Adachi M

doi

10.1007/BF02564863

keywords:

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

745-53

issue

6

eissn

0301-1623

issn

1573-2584

journal_volume

30

pub_type

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