Economic burden and cost-utility analysis of three renal replacement therapies in ESRD patients from Yunnan Province, China.

Abstract:

PURPOSE:To compare the economic burden and cost-utility analysis of the renal replacement therapies, including hemodialysis (HD), peritoneal dialysis (PD), and allograft kidney transplantation (KT) among end-stage renal disease (ESRD) patients from Yunnan Province, China. METHODS:Multistage stratified random sampling method was used to select presentative sample of 298 patients from four hospitals in Yunnan Province. The two-step model was applied to calculate a direct economic burden; the human capital approach was used to analyze the indirect economic burden. SF-36 scale was applied to assess the quality of life, while the improving score of quality of life was used to evaluate the cost-utility score. RESULTS:A total of 298 patients were analyzed, including 108 HD patients, 91 PD patients and 99 KT patients. The mean unit economic expenses of HD, PD, and KT were $11,783.6 ± 402.63, $11,059.8 ± 709.51, and $21,151.1 ± 11,419.57, respectively. Based on the cost-utility analysis, the cost of improving one unit of quality of life in KT, PD, and HD was $599.86, $1373.89 and $2021.20, respectively; a significant difference was observed between the KT group and the HD or PD group (P < 0.05). CONCLUSIONS:The economic burden of ESRD in Yunnan was substantial. The cost-utility was the best in the renal transplantation group. Kidney transplantation is still recommended as the first approach for patients with ESRD, followed by PD.

journal_name

Int Urol Nephrol

authors

Wu H,Li Q,Cai Y,Zhang J,Cui W,Zhou Z

doi

10.1007/s11255-020-02394-1

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

573-579

issue

3

eissn

0301-1623

issn

1573-2584

pii

10.1007/s11255-020-02394-1

journal_volume

52

pub_type

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