Abstract:
Purpose:Evaluating the risk of lymph node metastasis (LNM) is critical for determining subsequent treatments following endoscopic resection of T1 colorectal cancer (CRC). This study analyzed histopathologic risk factors for LNM in patients with T1 CRC. Methods:This study involved 745 patients with T1 CRC who underwent endoscopic (n = 97) or surgical (n = 648) resection between January 2001 and December 2015 at the National Cancer Center, Korea. LNM in endoscopically resected patients, which could not be evaluated directly, was estimated indirectly based on follow-up results and histopathologic reports of salvage surgery. The relationships of depth of submucosal invasion, histologic grade, budding, vascular invasion, and background adenoma with LNM were evaluated statistically. Results:Of the 745 patients, 91 (12.2%) were found to be positive for LNM. Univariate and multivariate analyses identified deep submucosal invasion (P = 0.010), histologic high grade (P < 0.001), budding (P = 0.034), and vascular invasion (P < 0.001) as risk factors for LNM. Among the patients with one, two, three, and four risk factors, 6.0%, 18.7%, 36.4%, and 100%, respectively, were positive for LNM. Conclusion:Deep submucosal invasion, histologic high grade, budding, and vascular invasion are risk factors for LNM in patients with T1 colorectal cancer. If any of these risk factors are present, additional surgery following endoscopic resection should be determined after considering the potential risk of LNM and each patient's situation.
journal_name
Ann Surg Treat Resjournal_title
Annals of surgical treatment and researchauthors
Ha RK,Han KS,Sohn DK,Kim BC,Hong CW,Chang HJ,Hyun JH,Kim MJ,Park SC,Oh JHdoi
10.4174/astr.2017.93.5.266subject
Has Abstractpub_date
2017-11-01 00:00:00pages
266-271issue
5eissn
2288-6575issn
2288-6796journal_volume
93pub_type
杂志文章abstract:PURPOSE:This study aimed to determine which factors affect the prognosis of hepatectomy for hepatocellular carcinoma (HCC) larger than 5 cm, including the prognostic difference between tumor sizes from 5-10 cm and larger than 10 cm. METHODS:The medical records of 114 patients who underwent hepatectomy for single HCC l...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.91.3.104
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:The aim of this study is to know whether silibinin has an anticancer effect on triple negative breast cancer xenograft model using MDA-MB-468 cells. METHODS:To establish the xenograft model, we injected the MDA-MB-468 cells into female Balb/c-nude mice. After establishing a xenograft model, oral silibinin was ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.87.4.167
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:Ultrasound-guided fine needle aspiration (US-FNA) in thyroid nodules is presently most commonly used to identify whether these nodules are benign or malignant. However, atypical or follicular lesions of undetermined significance (AUS/FLUS), as categorized in the Bethesda System for reporting the results of FNA,...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.90.4.201
更新日期:2016-04-01 00:00:00
abstract:Purpose:Repeating endoscopic retrograde cholangiopancreatography (ERCP) in patients with recurrent common bile duct (CBD) stones is problematic in many ways. Choledochoduodenostomy (CDS) and choledochojejunostomy (CJS) are 2 surgical treatment options for recurrent CBD stones, and each has different advantages and disa...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.6.329
更新日期:2020-12-01 00:00:00
abstract::Single-incision laparoscopic surgery has gained increasing attention due to its potential to improve the benefits of laparoscopic surgery. However, inconvenience remains for inexperienced surgeons during surgery when instruments conflict with each other, and a glove port is used hesitantly for such diagnosis related g...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2015.89.5.284
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:To identify the correlation of the model for end-stage liver disease (MELD) scores with the assessment of the risk of hepatic function after hemihepatectomy in patients with hepatocellular carcinoma (HCC) related to hepatitis B virus (HBV). METHODS:A case-control study was performed based on data for 141 conse...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.86.3.122
更新日期:2014-03-01 00:00:00
abstract::Hepatic tuberculosis (TB) is usually associated with pulmonary or miliary TB, but primary hepatic TB is very uncommon even in countries with high prevalence of TB. The clinical manifestation of primary hepatic TB is atypical and imaging modalities are unhelpful for differential diagnosis of the liver mass. Image-guide...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2015.89.2.98
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:Little is known about the clinicopathological features of early mucinous gastric carcinoma (MGC). The purpose of this study was to compare the clinicopathological features and prognosis between patients with early MGC and those with early nonmucinous gastric carcinoma (NMGC). METHODS:We reviewed the records of...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.87.1.5
更新日期:2014-07-01 00:00:00
abstract:Purpose:Thyroid reoperations are surgically challenging because of significant anatomical variance. Visual and functional identification of the external branch of the superior laryngeal nerve (EBSLN) were studied in 2 groups of patients who underwent primary and redo thyroid surgery. Methods:This study was conducted o...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.96.6.269
更新日期:2019-06-01 00:00:00
abstract:Purpose:Gastric emptying may influence the quality of life of patients who undergo distal gastrectomy. Little is known, however, about gastric emptying after distal gastrectomy. The aim of our study was to investigate gastric emptying patterns after distal gastrectomy. Methods:This gastric-emptying study investigated ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2017.93.6.310
更新日期:2017-12-01 00:00:00
abstract:Purpose:Preoperative chemoradiation therapy (CRT) has become the standard treatment for patients with locally advanced rectal cancer, 15%-30% of patients still progress while being treated with CRT. The aim of this study was to identify as important biomarker of poor response and evaluate the mechanism associated with ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.2.83
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:Management of appendicitis in children has always been an issue in pediatric surgery. Both diagnostic methods and treatment vary significantly among medical centers, and little consensus exists in many aspects of the care for patients with appendicitis. Here, we assessed the value of drain insertion after appen...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.6.341
更新日期:2015-06-01 00:00:00
abstract:Purpose:Infection remains the main cause of morbidity and mortality in liver transplantation (LT) recipients; however infection is notoriously difficult to diagnose because its usual signs and symptoms of infection may be masked or absent. This study comprises an analysis of bacterial infections in the early period aft...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2018.94.3.154
更新日期:2018-03-01 00:00:00
abstract:Purpose:To compare high and low inferior mesenteric artery (IMA) ligation in a large number of patients, and investigate the short-term and long-term outcomes. Methods:This retrospective study compared outcomes between high IMA ligation and low IMA ligation with dissection of lymph nodes (LNs) around the IMA origin. A...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.5.254
更新日期:2019-11-01 00:00:00
abstract:Purpose:Given the long history of investigation into cancer and its relevance to the lymph node (LN), it would be meaningful to plot the trends of research on cancer-related LN. Methods:Queries such as "cancer," "lymph node," and "cancer and lymph node" were submitted to PubMed to collect articles on cancer and LN pub...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.5.305
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:The factors related to early-onset tumor recurrence in patients with spontaneously ruptured hepatocellular carcinoma (HCC) after hepatectomy remain unclear. The aims of the present study were to compare characteristics between early and late recurrence groups in spontaneously ruptured HCC patients who received ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.91.1.17
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:We evaluate the operative outcome and oncologic outcome of laparoscopic liver resection for hepatocellular carcinoma (HCC), and compare with open liver resection. METHODS:From January 2004 to December 2012, clinical data of 70 patients who underwent laparoscopic liver resection for HCC (laparoscopic liver rese...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.86.2.61
更新日期:2014-02-01 00:00:00
abstract:Purpose:Clinically suspected T4 stage colon cancer from a preoperative exam is often diagnosed as T3 stage colon cancer pathologically after surgery, raising concerns about understaging. The aims of this study were to compare the survival of clinical T3 and T4 colon cancer patients who had received a pathologic T3 stag...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.1.37
更新日期:2020-07-01 00:00:00
abstract:Purpose:Spontaneous gastrointestinal perforations (SGIPs; not associated with injury or disease) occur rarely in pediatric patients. This study aimed to define age-specific features associated with SGIPs in pediatric patients. Methods:Retrospectively reviewed the clinical data of children (before adolescence) who rece...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2018.95.3.141
更新日期:2018-09-01 00:00:00
abstract:Purpose:Many patients with cytology proven node-positive breast cancer receive a neoadjuvant chemotherapy (NAC) treatment. We developed a nomogram to predict the breast and axillary pathologic complete responses (pCR) in patients with a cytologically proven axillary node positive breast cancer with NAC. Methods:We sel...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.96.4.169
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:To investigate the feasibility and safety of solo surgery with single-port laparoscopic appendectomy, which is termed herein solo-SPLA (solo-single-port laparoscopic appendectomy). METHODS:This study prospectively collected and retrospectively analyzed data from patients who had undergone either non-solo-SPLA ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.90.3.164
更新日期:2016-03-01 00:00:00
abstract::Endovascular aneurysm repair is a minimally invasive, durable and effective alternative to open surgery for treatment of abdominal aortic aneurysms (AAA). However, in patients who do not have an adequate sealing zone, open surgical repair is required, which may increase mortality and morbidity. An alternative treatmen...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2014.86.5.274
更新日期:2014-05-01 00:00:00
abstract:Purpose:Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. We tested whether quantification of urinary TG2 may represent a noninvasive method to estimate the severity of kidney allograft fibrosis. Methods:We prospectively collected urine specimens from ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.1.27
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:Downstaging after chemoradiotherapy (CRT) for rectal cancer usually occurs. The present study aimed to evaluate pathologic y-stage (yp-stage) and its influence on local recurrence and systemic recurrence in rectal cancer patients treated with CRT followed by surgical resection. METHODS:We retrospectively analy...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.1.15
更新日期:2015-01-01 00:00:00
abstract::The concept of complete mesocolic excision and central vascular ligation for colonic cancer has been recently introduced. The paper describes a technique of right-sided complete mesocolic excision and intracorporeal anastomosis by using a single-port robotic approach with an additional conventional robotic port. We pe...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.91.4.212
更新日期:2016-10-01 00:00:00
abstract:Purpose:Meckel diverticulum (MD), caused by an obliteration defect of the omphalomesenteric duct, is one of the most common congenital anomalies of small intestines. The objective of this study was to review surgical outcomes of MD and evaluate the feasibility of minimally invasive surgery (MIS) in MD. Methods:We perf...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.4.213
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the effectiveness and safety of monitored anesthesia care (MAC) using dexmedetomidine for its sedative and analgesic effect during varicose vein surgery. METHODS:Forty-two patients, who underwent varicose vein surgery, were divided into the MAC group (n = 20) or the...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.87.5.245
更新日期:2014-11-01 00:00:00
abstract::Gastrointestinal (GI) tract metastasis of primary breast cancer is very rare. We present a patient with small bowel obstruction from distant metastasis of primary breast cancer. Each characteristic features of concern of GI tract distant metastasis from many pervious studies has been reported differently. We should re...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2018.94.2.102
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:Laparoscopic fundoplication is considered the standard surgical treatment for gastroesophageal reflux disease (GERD) in Western countries. However, some patients experience poor surgical outcomes with this procedure. The study aimed to identify the predictive factors of the surgical outcomes of laparoscopic Nis...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2017.92.4.184
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:Bariatric surgery has become more prevalent owing to the worldwide obesity epidemic. With the growing number of bariatric procedures performed annually, the requirement for revisional and secondary operations is increasing accordingly. This study aimed to evaluate the initial experience of revisional bariatric ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.86.6.295
更新日期:2014-06-01 00:00:00