Clinicopathological factors increased the risk of malignancy in thyroid nodules with atypical or follicular lesions of undetermined significance (AUS/FLUS) risk factor of malignancy in thyroid nodule with AUS/FLUS.

Abstract:

PURPOSE:Ultrasound-guided fine needle aspiration (US-FNA) in thyroid nodules is presently most commonly used to identify whether these nodules are benign or malignant. However, atypical or follicular lesions of undetermined significance (AUS/FLUS), as categorized in the Bethesda System for reporting the results of FNA, cannot be classified as benign or malignant. Therefore, several clinical factors should be considered to assess the risk of malignancy in patients with AUS/FLUS. The purpose of the present study was to determine which clinical factor increased the risk of malignancy in patients with AUS/FLUS. METHODS:A retrospective study was done on 129 patients with fine needle aspiration categorized as AUS/FLUS from January 2011 through April 2015. Univariate and multivariate analyses were performed to assess the independent effect of risk factors such as age, sex, size of nodule, atypical descriptors, and ultrasonography criteria for malignancy. RESULTS:We identified that the presence of spiculated margin (odds ratio [OR], 5.655; 95% confidence interval [CI], 2.114-15.131; P = 0.001), nuclear grooving (OR, 3.697; 95% CI, 1.409-9.701; P = 0.008), irregular nuclei (OR, 3.903; 95% CI, 1.442-10.560; P = 0.001) were shown to be significantly related to malignancy on univariate and multivariate analyses. CONCLUSION:We recommend that surgical resection of thyroid nodules be considered in patients with AUS/FLUS showing the histologic findings such as nuclear grooving, irregular nuclei along with spiculated margin of ultrasonographic finding.

journal_name

Ann Surg Treat Res

authors

Hong IK,Kim JH,Cho YU,Park SY,Kim SJ

doi

10.4174/astr.2016.90.4.201

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

201-6

issue

4

eissn

2288-6575

issn

2288-6796

journal_volume

90

pub_type

杂志文章
  • Streamline flow of the portal vein affects the lobar distribution of colorectal liver metastases and has a clinical impact on survival.

    abstract:PURPOSE:It is believed that blood from the superior mesenteric vein and splenic vein mixes incompletely in the portal vein and maintains a streamline flow influencing its anatomic distribution. Although several experimental studies have demonstrated the existence of streamlining, clinical studies have shown conflicting...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2017.92.5.348

    authors: Rhu J,Heo JS,Choi SH,Choi DW,Kim JM,Joh JW,Kwon CHD

    更新日期:2017-05-01 00:00:00

  • Factors predicting outcomes of laparoscopic Nissen fundoplication for gastroesophageal reflux disease: experience at a single institution in Korea.

    abstract:PURPOSE:Laparoscopic fundoplication is considered the standard surgical treatment for gastroesophageal reflux disease (GERD) in Western countries. However, some patients experience poor surgical outcomes with this procedure. The study aimed to identify the predictive factors of the surgical outcomes of laparoscopic Nis...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2017.92.4.184

    authors: Park JM,Kim BJ,Kim JG,Chi KC

    更新日期:2017-04-01 00:00:00

  • Tenofovir does not induce renal dysfunction compared to entecavir in post-liver-transplant hepatitis B virus patients.

    abstract:Purpose:Tenofovir disoproxil fumarate is accepted as an effective and tolerable drug for treatment of HBV, similar to entecavir. However, there are some concerns about the nephrotoxicity of tenofovir. The aim of this study is to compare the renal-function change of liver recipients who received tenofovir or entecavir f...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2020.99.3.180

    authors: Kim SJ,Rhu J,Lee SH,Kim JM,Choi GS,Kim K,Joh JW

    更新日期:2020-09-01 00:00:00

  • Small bowel obstruction from distant metastasis of primary breast cancer: a case report.

    abstract::Gastrointestinal (GI) tract metastasis of primary breast cancer is very rare. We present a patient with small bowel obstruction from distant metastasis of primary breast cancer. Each characteristic features of concern of GI tract distant metastasis from many pervious studies has been reported differently. We should re...

    journal_title:Annals of surgical treatment and research

    pub_type:

    doi:10.4174/astr.2018.94.2.102

    authors: Oh SJ,Park SY,Kim JY,Yim H,Jung Y,Han SH

    更新日期:2018-02-01 00:00:00

  • Mortality risk factor analysis in colonic perforation: would retroperitoneal contamination increase mortality in colonic perforation?

    abstract:Purpose:Colonic perforation is a lethal condition presenting high morbidity and mortality in spite of urgent surgical treatment. This study investigated the surgical outcome of patients with colonic perforation associated with retroperitoneal contamination. Methods:Retrospective analysis was performed for 30 patients ...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2017.93.4.203

    authors: Yoo RN,Kye BH,Kim G,Kim HJ,Cho HM

    更新日期:2017-10-01 00:00:00

  • Novel method of laparoendoscopic single-site and natural orifice specimen extraction for live donor nephrectomy: single-port laparoscopic donor nephrectomy and transvaginal graft extraction.

    abstract::Laparoscopic live donor nephrectomy (DN) has been established as a useful alternative to the traditional open methods of procuring kidneys. To maximize the advantages of the laparoendoscopic single-site (LESS) method, we applied natural orifice specimen extraction to LESS-DN. A 46-year-old woman with no previous abdom...

    journal_title:Annals of surgical treatment and research

    pub_type:

    doi:10.4174/astr.2016.90.2.111

    authors: Jeong WJ,Choi BJ,Hwang JK,Yuk SM,Song MJ,Lee SC

    更新日期:2016-02-01 00:00:00

  • Primary hepatic tuberculosis mimicking intrahepatic cholangiocarcinoma: report of two cases.

    abstract::Hepatic tuberculosis (TB) is usually associated with pulmonary or miliary TB, but primary hepatic TB is very uncommon even in countries with high prevalence of TB. The clinical manifestation of primary hepatic TB is atypical and imaging modalities are unhelpful for differential diagnosis of the liver mass. Image-guide...

    journal_title:Annals of surgical treatment and research

    pub_type:

    doi:10.4174/astr.2015.89.2.98

    authors: Park JI

    更新日期:2015-08-01 00:00:00

  • The nutritional risk is a independent factor for postoperative morbidity in surgery for colorectal cancer.

    abstract:PURPOSE:The authors evaluate the prevalence of malnutrition and its effect on the postoperative morbidity of patients after surgery for colorectal cancer. METHODS:Three hundred fifty-two patients were enrolled prospectively. Nutritional risk screening 2002 (NRS 2002) score was calculated through interview with patient...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2014.86.4.206

    authors: Kwag SJ,Kim JG,Kang WK,Lee JK,Oh ST

    更新日期:2014-04-01 00:00:00

  • Chronologic trends of cancer-related lymph node research in PubMed: informetrics analysis.

    abstract:Purpose:Given the long history of investigation into cancer and its relevance to the lymph node (LN), it would be meaningful to plot the trends of research on cancer-related LN. Methods:Queries such as "cancer," "lymph node," and "cancer and lymph node" were submitted to PubMed to collect articles on cancer and LN pub...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2020.99.5.305

    authors: Oh HJ,Yang D,Oh HW,Jeon JG,Kim C,Ahn JY,Han SW,Kim CY

    更新日期:2020-11-01 00:00:00

  • Focal change of the pancreatic texture using a direct injection mixture of N-butyl cyanoacrylate and lipiodol in the pig model: a strategy for preventing pancreatic leakage during pancreatic surgery.

    abstract:Purpose:A soft texture of the pancreas is one of the most important predisposing factors for a pancreatic fistula. Thus, in a porcine model, we investigated a method to harden the pancreas locally by directly injecting an artificial material. Methods:During the laparotomy, 51 samples from 17 pigs, including 13 surviva...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2018.95.4.175

    authors: Kim EY,Hong TH

    更新日期:2018-10-01 00:00:00

  • Learning curves for single incision and conventional laparoscopic right hemicolectomy: a multidimensional analysis.

    abstract:PURPOSE:This study aimed to compare the learning curves and early postoperative outcomes for conventional laparoscopic (CL) and single incision laparoscopic (SIL) right hemicolectomy (RHC). METHODS:This retrospective study included the initial 35 cases in each group. Learning curves were evaluated by the moving averag...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2015.88.5.269

    authors: Park Y,Yong YG,Yun SH,Jung KU,Huh JW,Cho YB,Kim HC,Lee WY,Chun HK

    更新日期:2015-05-01 00:00:00

  • Drain insertion after appendectomy in children with perforated appendicitis based on a single-center experience.

    abstract:PURPOSE:Management of appendicitis in children has always been an issue in pediatric surgery. Both diagnostic methods and treatment vary significantly among medical centers, and little consensus exists in many aspects of the care for patients with appendicitis. Here, we assessed the value of drain insertion after appen...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2015.88.6.341

    authors: Song RY,Jung K

    更新日期:2015-06-01 00:00:00

  • A comparison of postoperative pain after conventional open thyroidectomy and single-incision, gasless, endoscopic transaxillary thyroidectomy: a single institute prospective study.

    abstract:PURPOSE:The aim of this study was to compare postoperative pain between single-incision, gasless, endoscopic transaxillary thyroidectomy (SET), and conventional open thyroidectomy. METHODS:From March to December 2015, patients with thyroid disease underwent total thyroidectomy or lobectomy. Patient's clinical and path...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2017.92.1.9

    authors: Kang JB,Kim EY,Park YL,Park CH,Yun JS

    更新日期:2017-01-01 00:00:00

  • Separate thyrothymic thyroid remnant; clinically crucial anatomic variation.

    abstract:Purpose:The anatomical variations of the thyroid gland including separate thyroidal remnant at the thyrothymic area are of significance during thyroid surgery for "total" thyroidectomy, and for recurrent goitre. In the present study, we aimed to detect the separate rests of thyroidal tissue in the thyrothymic region. ...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2020.98.3.111

    authors: Gurleyik E,Gurleyik G

    更新日期:2020-03-01 00:00:00

  • The advantages of early trauma team activation in the management of major trauma patients who underwent exploratory laparotomy.

    abstract:PURPOSE:Trauma team activation (TTA) has been shown to have fundamental impact on trauma patients' outcomes. The purpose of this study was to evaluate the short-term outcomes of use of a new TTA protocol in the management of major trauma patients who underwent exploratory laparotomy. METHODS:The medical records of tra...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2014.87.6.319

    authors: Yoo Y,Mun S

    更新日期:2014-12-01 00:00:00

  • Anticancer effect of silibinin on the xenograft model using MDA-MB-468 breast cancer cells.

    abstract:PURPOSE:The aim of this study is to know whether silibinin has an anticancer effect on triple negative breast cancer xenograft model using MDA-MB-468 cells. METHODS:To establish the xenograft model, we injected the MDA-MB-468 cells into female Balb/c-nude mice. After establishing a xenograft model, oral silibinin was ...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2014.87.4.167

    authors: Kil WH,Kim SM,Lee JE,Park KS,Nam SJ

    更新日期:2014-10-01 00:00:00

  • The characteristics of antireflux surgery compared to proton pump inhibitor treatment in Korea: a nationwide study using claim data from 2007 to 2016.

    abstract:Purpose:Laparoscopic antireflux surgery is not widely used in Korea, but published data suggest that its results are comparable to those of Western countries. The purpose of this study was to compare the clinical characteristics, medical utilization, and medical costs of antireflux surgery and proton pump inhibitor (PP...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2020.98.5.254

    authors: Park S,Kwon JW,Park JM,Park S,Hwang J,Seo KW

    更新日期:2020-05-01 00:00:00

  • Is the "ghost surgery" the subject of legal punishment in Korea?

    abstract:Purpose:Recently a controversy has arisen about so-called "ghost surgery" practices, and people have voiced their opinions for legal sanction against such practices, which clearly undermine the foundation of medical ethics. However, there has been a lack of legal basis for punishing those actions. The present study aim...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2018.94.4.167

    authors: Hong SE,Hong MK,Park BY,Woo KJ,Kang SR

    更新日期:2018-04-01 00:00:00

  • Trends in contralateral prophylactic mastectomy rate according to clinicopathologic and socioeconomic status.

    abstract:Purpose:There has been an increasing trend in the use of contralateral prophylactic mastectomy (CPM) among women diagnosed with unilateral breast cancer or mutations in BRCA1 or BRCA2 to reduce the occurrence of contralateral breast cancer. This study aimed to examine trends in the CPM rate according to clinicopatholog...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2019.97.3.113

    authors: Jeon HJ,Park HS,Park JS,Nam EJ,Lee ST,Han J

    更新日期:2019-09-01 00:00:00

  • Clinical features of gastric emptying after distal gastrectomy.

    abstract:Purpose:Gastric emptying may influence the quality of life of patients who undergo distal gastrectomy. Little is known, however, about gastric emptying after distal gastrectomy. The aim of our study was to investigate gastric emptying patterns after distal gastrectomy. Methods:This gastric-emptying study investigated ...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2017.93.6.310

    authors: Kim DH,Yun HY,Song YJ,Ryu DH,Han HS,Han JH,Kim KB,Yoon SM,Youn SJ

    更新日期:2017-12-01 00:00:00

  • The effects of ventilation with high density oxygen on the strength of gastrointestinal anastomosis.

    abstract:PURPOSE:The aim of our study is to evaluate the effects of administration of perioperative supplemental oxygen on anastomoses. METHODS:Forty male Wistar albino rats were used in the study and randomized into 4 groups. Ischemia-reperfusion models were built in groups 3 and 4. Jejunojejunostomy was performed in all rats...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2015.89.1.17

    authors: Eker T,Genc V,Sevim Y,Cumaogullari O,Ozcelik M,Kocaay AF,Ensari CÖ,Pasaoglu OT

    更新日期:2015-07-01 00:00:00

  • Clinical significance of revised microscopic positive resection margin status in ductal adenocarcinoma of pancreatic head.

    abstract:Purpose:Recent studies have suggested microscopic positive resection margin should be revised according to the presence of tumor cells within 1mm of the margin surface in resected specimens of pancreatic cancer. However, the clinical meaning of this revised margin status for R1 resection margin was not fully clarified....

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2019.96.1.19

    authors: You Y,Choi DW,Heo JS,Han IW,Choi SH,Jang KT,Han S,Han SH

    更新日期:2019-01-01 00:00:00

  • Nomogram for accurate prediction of breast and axillary pathologic response after neoadjuvant chemotherapy in node positive patients with breast cancer.

    abstract:Purpose:Many patients with cytology proven node-positive breast cancer receive a neoadjuvant chemotherapy (NAC) treatment. We developed a nomogram to predict the breast and axillary pathologic complete responses (pCR) in patients with a cytologically proven axillary node positive breast cancer with NAC. Methods:We sel...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2019.96.4.169

    authors: Choi HJ,Ryu JM,Kim I,Nam SJ,Kim SW,Yu J,Lee JE,Lee SK

    更新日期:2019-04-01 00:00:00

  • Long-term results of laparoscopic common bile duct exploration by choledochotomy for choledocholithiasis: 15-year experience from a single center.

    abstract:PURPOSE:The aim of this study is to assess the long-term results of laparoscopic common bile duct exploration (LCBDE) and validate its effectiveness as a primary treatment modality for CBD stone. METHODS:A retrospective review of the medical records of 157 patients who underwent LCBDE from 1997 to 2011 was conducted. ...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2014.86.1.1

    authors: Lee HM,Min SK,Lee HK

    更新日期:2014-01-01 00:00:00

  • Radiation hazards to vascular surgeon and scrub nurse in mobile fluoroscopy equipped hybrid vascular room.

    abstract:PURPOSE:The aim of the present study was to identify the radiation hazards to vascular surgeons and scrub nurses working in mobile fluoroscopy equipped hybrid vascular operation rooms; additionally, to estimate cumulative cancer risk due to certain exposure dosages. METHODS:The study was conducted prospectively in 71 ...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2017.92.3.156

    authors: Kim JB,Lee J,Park K

    更新日期:2017-03-01 00:00:00

  • The comparison of monitored anesthesia care with dexmedetomidine and spinal anesthesia during varicose vein surgery.

    abstract:PURPOSE:The purpose of this study was to investigate the effectiveness and safety of monitored anesthesia care (MAC) using dexmedetomidine for its sedative and analgesic effect during varicose vein surgery. METHODS:Forty-two patients, who underwent varicose vein surgery, were divided into the MAC group (n = 20) or the...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2014.87.5.245

    authors: Moon EJ,Kang KW,Chung JY,Kang JM,Park JH,Joh JH,Park HC,Yi JW

    更新日期:2014-11-01 00:00:00

  • The feasibility of single-port laparoscopic appendectomy using a solo approach: a comparative study.

    abstract:PURPOSE:To investigate the feasibility and safety of solo surgery with single-port laparoscopic appendectomy, which is termed herein solo-SPLA (solo-single-port laparoscopic appendectomy). METHODS:This study prospectively collected and retrospectively analyzed data from patients who had undergone either non-solo-SPLA ...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2016.90.3.164

    authors: Kim SJ,Choi BJ,Jeong W,Lee SC

    更新日期:2016-03-01 00:00:00

  • Effect of IL-18 binding protein on hepatic ischemia-reperfusion injury induced by infrarenal aortic occlusion.

    abstract:PURPOSE:Severe local and systemic tissue damage called ischemia/reperfusion (IR) injury occurs during the period of reperfusion. Free oxygen radicals and proinflammatory cytokines are responsible for reperfusion injury. IL-18 binding protein (IL-18BP) is a natural inhibitor of IL-18. The balance between IL-18 and IL-18...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2015.88.2.92

    authors: Ozsoy M,Gonul Y,Bal A,Ozkececi ZT,Celep RB,Adali F,Hazman O,Koçak A,Tosun M

    更新日期:2015-02-01 00:00:00

  • ERRATUM: Correction of funding statement in ACKNOWLEDGEMENTS section. Effectiveness of thymoquinone, zeolite, and platelet-rich plasma in model of corrosive oesophagitis induced in rats.

    abstract::[This corrects the article on p. 396 in vol. 92, PMID: 28580343.]. ...

    journal_title:Annals of surgical treatment and research

    pub_type: 已发布勘误

    doi:10.4174/astr.2017.93.2.118

    authors: Karaca G,Aydin O,Pehlivanli F,Altunkaya C,Uzun H,Güler O

    更新日期:2017-08-01 00:00:00

  • Causes and outcomes of revisional bariatric surgery: initial experience at a single center.

    abstract:PURPOSE:Bariatric surgery has become more prevalent owing to the worldwide obesity epidemic. With the growing number of bariatric procedures performed annually, the requirement for revisional and secondary operations is increasing accordingly. This study aimed to evaluate the initial experience of revisional bariatric ...

    journal_title:Annals of surgical treatment and research

    pub_type: 杂志文章

    doi:10.4174/astr.2014.86.6.295

    authors: Park JY,Song D,Kim YJ

    更新日期:2014-06-01 00:00:00