The effects of ventilation with high density oxygen on the strength of gastrointestinal anastomosis.

Abstract:

PURPOSE:The aim of our study is to evaluate the effects of administration of perioperative supplemental oxygen on anastomoses. METHODS:Forty male Wistar albino rats were used in the study and randomized into 4 groups. Ischemia-reperfusion models were built in groups 3 and 4. Jejunojejunostomy was performed in all rats and assigned to an oxygen/nitrous oxide mixture with a fraction of inspired oxygen of 30% in groups 1 and 3 and 80% in groups 2 and 4. The measurements of perianastomotic tissue oxygen pressure, bursting pressure, level of hydroxyproline were evaluated and compared in all groups. RESULTS:The perianastomotic tissue oxygen pressures, bursting pressures and levels of hydroxyproline were identified as significantly high in groups 2 and 4, administered a fraction of inspired oxygen of 80%, compared to groups 1 and 3, administered a fraction of inspired oxygen of 30%. CONCLUSION:Perioperative supplemental oxygen contributes positively to the anastomotic healing.

journal_name

Ann Surg Treat Res

authors

Eker T,Genc V,Sevim Y,Cumaogullari O,Ozcelik M,Kocaay AF,Ensari CÖ,Pasaoglu OT

doi

10.4174/astr.2015.89.1.17

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

17-22

issue

1

eissn

2288-6575

issn

2288-6796

journal_volume

89

pub_type

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