Abstract:
PURPOSE:To determine the prevalence of thrombophilia in Korean patients with an arterial thromboembolism (ATE) or a venous thromboembolism (VTE), and to evaluate the characteristic of VTE in patients with thrombophilia. METHODS:Hospital records of 294 patients (228 with VTE, 66 with ATE) including two foreign ones (mean age, 51.4 years) who underwent thrombophilia testing between August 2006 and March 2015 were reviewed retrospectively. In general, such screening was performed according to the guidelines of the international consensus statement for VTE. Thrombophilia testing included evaluations of the factor V Leiden and prothrombin G20210A mutations, levels of proteins C and S and antithrombin, and antiphospholipid antibody syndrome (APLS). RESULTS:A factor V Leiden mutation was not found in the 292 Korean patients. A prothrombin G21210A mutation was investigated in 33 patients but none was found. Among 226 Korean patients with VTE, 130 demonstrated no thrombophilia and 55 patients did after exclusion of 41 patients without confirmatory test. The most common form was protein S deficiency (31 of 55, 56%) followed by protein C deficiency, antithrombin deficiency, and APLS. When comparing patients with a VTE or deep vein thrombosis (DVT) according to the presence of thrombophilia, thrombophilia was associated with younger age (P = 0.001 for VTE; P < 0.001 for DVT) and a family history (P < 0.001 for VTE and DVT). CONCLUSION:We did not find any factor V Leiden mutation in Korean subjects at high risk for thrombophilia. Therefore, this testing is not warranted. Thrombophilia was associated with VTE in younger age and a family history.
journal_name
Ann Surg Treat Resjournal_title
Annals of surgical treatment and researchauthors
Kim S,Song I,Kim HK,Huh Sdoi
10.4174/astr.2016.90.6.340subject
Has Abstractpub_date
2016-06-01 00:00:00pages
340-5issue
6eissn
2288-6575issn
2288-6796journal_volume
90pub_type
杂志文章abstract:Purpose:The anatomical variations of the thyroid gland including separate thyroidal remnant at the thyrothymic area are of significance during thyroid surgery for "total" thyroidectomy, and for recurrent goitre. In the present study, we aimed to detect the separate rests of thyroidal tissue in the thyrothymic region. ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.98.3.111
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:The postoperative treatment after appendectomy is usually decided on the basis of the surgeons' intraoperative findings. Comparatively, the pathologic diagnosis of appendicitis is confirmed several days after the surgery; therefore, it usually does not affect the postoperative treatment strategy. The aim of thi...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2017.93.1.43
更新日期:2017-07-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare postoperative pain between single-incision, gasless, endoscopic transaxillary thyroidectomy (SET), and conventional open thyroidectomy. METHODS:From March to December 2015, patients with thyroid disease underwent total thyroidectomy or lobectomy. Patient's clinical and path...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2017.92.1.9
更新日期:2017-01-01 00:00:00
abstract::Laparoscopic live donor nephrectomy (DN) has been established as a useful alternative to the traditional open methods of procuring kidneys. To maximize the advantages of the laparoendoscopic single-site (LESS) method, we applied natural orifice specimen extraction to LESS-DN. A 46-year-old woman with no previous abdom...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2016.90.2.111
更新日期:2016-02-01 00:00:00
abstract:Purpose:To compare high and low inferior mesenteric artery (IMA) ligation in a large number of patients, and investigate the short-term and long-term outcomes. Methods:This retrospective study compared outcomes between high IMA ligation and low IMA ligation with dissection of lymph nodes (LNs) around the IMA origin. A...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.5.254
更新日期:2019-11-01 00:00:00
abstract:Purpose:The incidence of colonic diverticular disease is increasing, and several grading systems based on CT findings have been developed. The objective of this study was to define the impact of various CT findings of colonic diverticulitis and to demonstrate which factors affect the need for operative treatment. Meth...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2018.94.6.322
更新日期:2018-06-01 00:00:00
abstract:Purpose:Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. We tested whether quantification of urinary TG2 may represent a noninvasive method to estimate the severity of kidney allograft fibrosis. Methods:We prospectively collected urine specimens from ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.1.27
更新日期:2019-07-01 00:00:00
abstract:Purpose:A soft texture of the pancreas is one of the most important predisposing factors for a pancreatic fistula. Thus, in a porcine model, we investigated a method to harden the pancreas locally by directly injecting an artificial material. Methods:During the laparotomy, 51 samples from 17 pigs, including 13 surviva...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2018.95.4.175
更新日期:2018-10-01 00:00:00
abstract:Purpose:Given the long history of investigation into cancer and its relevance to the lymph node (LN), it would be meaningful to plot the trends of research on cancer-related LN. Methods:Queries such as "cancer," "lymph node," and "cancer and lymph node" were submitted to PubMed to collect articles on cancer and LN pub...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.5.305
更新日期:2020-11-01 00:00:00
abstract:Purpose:Tenofovir disoproxil fumarate is accepted as an effective and tolerable drug for treatment of HBV, similar to entecavir. However, there are some concerns about the nephrotoxicity of tenofovir. The aim of this study is to compare the renal-function change of liver recipients who received tenofovir or entecavir f...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.3.180
更新日期:2020-09-01 00:00:00
abstract::We report a case of synchronous multiple colon adenocarcinomas in a patient with neurofibromatosis type 1 (NF1). NF1 is an autosomal dominant inherited disorder and patients with NF1 have high risk for both benign and malignant tumors. However, adenocarcinomas involving the colon have rarely been reported in patients ...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2014.87.3.156
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:Recently, the number of elderly patients has increased due to a longer life expectancy. Among these elderly patients, more octogenarians will be diagnosed with major hepatobiliary pancreatic (HBP) diseases. Therefore, we need to evaluate the safety and risk factors of major HBP surgery in patients older than 80...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.91.6.288
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:The aim of the present study was to identify the radiation hazards to vascular surgeons and scrub nurses working in mobile fluoroscopy equipped hybrid vascular operation rooms; additionally, to estimate cumulative cancer risk due to certain exposure dosages. METHODS:The study was conducted prospectively in 71 ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2017.92.3.156
更新日期:2017-03-01 00:00:00
abstract::Single-incision laparoscopic surgery has gained increasing attention due to its potential to improve the benefits of laparoscopic surgery. However, inconvenience remains for inexperienced surgeons during surgery when instruments conflict with each other, and a glove port is used hesitantly for such diagnosis related g...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2015.89.5.284
更新日期:2015-11-01 00:00:00
abstract:Purpose:Colonic perforation is a lethal condition presenting high morbidity and mortality in spite of urgent surgical treatment. This study investigated the surgical outcome of patients with colonic perforation associated with retroperitoneal contamination. Methods:Retrospective analysis was performed for 30 patients ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2017.93.4.203
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:This study aimed to determine the mortality rate in patients with severe trauma and the risk factors for trauma mortality based on 3 years' data in a regional trauma center in Korea. METHODS:We reviewed the medical records of severe trauma patients admitted to Ajou University Hospital with an Injury Severity S...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.89.4.215
更新日期:2015-10-01 00:00:00
abstract:Purpose:Skin grafts have been widely used in managing extensive chest wall defects after mastectomy for advanced breast cancer. However, their durability and tolerability to radiotherapy is still controversial. A thoracoabdominal (TA) flap with a few technical refinements can safely transfer a larger flap while minimiz...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.4.168
更新日期:2019-10-01 00:00:00
abstract::Anastomotic leakage following rectal resection is a serious and fearful complication, and may cause presacral abscess and/or peritonitis. To our knowledge, massive hematochezia secondary to presacral abscess caused by anastomotic leakage has not yet been reported in the literature. We observed this rare and life-threa...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2015.88.4.236
更新日期:2015-04-01 00:00:00
abstract::Pediatric arterial aneurysm is rare disease. Among them, idiopathic-congenital arterial aneurysm is extremely rare. This is a case report of right common iliac artery idiopathic aneurysm with absence of right external iliac artery. A 4-year-old girl who had been complaining of intermittent abdominal pain since 2 years...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2016.91.5.265
更新日期:2016-11-01 00:00:00
abstract:Purpose:There has been an increasing trend in the use of contralateral prophylactic mastectomy (CPM) among women diagnosed with unilateral breast cancer or mutations in BRCA1 or BRCA2 to reduce the occurrence of contralateral breast cancer. This study aimed to examine trends in the CPM rate according to clinicopatholog...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.3.113
更新日期:2019-09-01 00:00:00
abstract:PURPOSE:The aim of our study is to evaluate the effects of administration of perioperative supplemental oxygen on anastomoses. METHODS:Forty male Wistar albino rats were used in the study and randomized into 4 groups. Ischemia-reperfusion models were built in groups 3 and 4. Jejunojejunostomy was performed in all rats...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.89.1.17
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:The authors evaluate the prevalence of malnutrition and its effect on the postoperative morbidity of patients after surgery for colorectal cancer. METHODS:Three hundred fifty-two patients were enrolled prospectively. Nutritional risk screening 2002 (NRS 2002) score was calculated through interview with patient...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.86.4.206
更新日期:2014-04-01 00:00:00
abstract::Vitelline veins are a pair of embryonic structures. The veins develop the portal vein system. Serious problems occur if the vitelline vein does not regress and becomes an aneurysm. Thrombus formation in the vitelline vein aneurysm could lead to portal vein thrombosis and portal hypertension unless promptly and correct...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2015.89.6.334
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To investigate the feasibility and safety of solo surgery with single-port laparoscopic appendectomy, which is termed herein solo-SPLA (solo-single-port laparoscopic appendectomy). METHODS:This study prospectively collected and retrospectively analyzed data from patients who had undergone either non-solo-SPLA ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.90.3.164
更新日期:2016-03-01 00:00:00
abstract:Purpose:Meckel diverticulum (MD), caused by an obliteration defect of the omphalomesenteric duct, is one of the most common congenital anomalies of small intestines. The objective of this study was to review surgical outcomes of MD and evaluate the feasibility of minimally invasive surgery (MIS) in MD. Methods:We perf...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.4.213
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:This study aimed to compare the learning curves and early postoperative outcomes for conventional laparoscopic (CL) and single incision laparoscopic (SIL) right hemicolectomy (RHC). METHODS:This retrospective study included the initial 35 cases in each group. Learning curves were evaluated by the moving averag...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.5.269
更新日期:2015-05-01 00:00:00
abstract:Purpose:To evaluate superiority of a night float (NF) system in comparison to a traditional night on-call (NO) system for surgical residents at a single institution in terms of efficacy, safety, and satisfaction. Methods:A NF system was implemented from March to September 2017 and big data analysis from electronic med...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.96.5.209
更新日期:2019-05-01 00:00:00
abstract:Purpose:Many patients with cytology proven node-positive breast cancer receive a neoadjuvant chemotherapy (NAC) treatment. We developed a nomogram to predict the breast and axillary pathologic complete responses (pCR) in patients with a cytologically proven axillary node positive breast cancer with NAC. Methods:We sel...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.96.4.169
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:We evaluate the operative outcome and oncologic outcome of laparoscopic liver resection for hepatocellular carcinoma (HCC), and compare with open liver resection. METHODS:From January 2004 to December 2012, clinical data of 70 patients who underwent laparoscopic liver resection for HCC (laparoscopic liver rese...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.86.2.61
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:The aim of this study is to assess the long-term results of laparoscopic common bile duct exploration (LCBDE) and validate its effectiveness as a primary treatment modality for CBD stone. METHODS:A retrospective review of the medical records of 157 patients who underwent LCBDE from 1997 to 2011 was conducted. ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.86.1.1
更新日期:2014-01-01 00:00:00