Abstract:
Purpose:Tenofovir disoproxil fumarate is accepted as an effective and tolerable drug for treatment of HBV, similar to entecavir. However, there are some concerns about the nephrotoxicity of tenofovir. The aim of this study is to compare the renal-function change of liver recipients who received tenofovir or entecavir for HBV. Methods:Among 468 patients with HBV who underwent liver transplantation at Samsung Medical Center between January 2008 and December 2015, the patients treated with tenofovir (n = 39) or entecavir (n = 429) were reviewed retrospectively. Baseline characteristics and renal-function change after 1 month, 1 year, and 2 years were compared. Propensity-score matching was performed for 37 patients using tenofovir and 132 patients using entecavir. We also analyzed risk factors of renal dysfunction. Results:Age, preoperative creatinine, estimated glomerular filtration rate (e-GFR), and hepatic encephalopathy score showed statistical difference between the tenofovir and entecavir groups. The proportion of patients with 'decreased renal function (e-GFR < 60 mL/min/1.73 m2)' was higher in the tenofovir group than in the entecavir group (33.3% vs. 12.4% at postoperative one year, P < 0.005). After propensity-score matching, there was no statistical difference in preoperative characteristics. Postoperative 1-, 2-, and 3-year e-GFR and creatinine showed no statistical difference in either group. On multivariate analysis, only preoperative high e-GFR showed a protective effect on renal-function change (odds ratio, 0.97; P < 0.001), and there was no aggravating factor. Conclusion:Tenofovir disoproxil fumarate does not induce renal dysfunction in liver-transplanted patients with HBV more than does entecavir.
journal_name
Ann Surg Treat Resjournal_title
Annals of surgical treatment and researchauthors
Kim SJ,Rhu J,Lee SH,Kim JM,Choi GS,Kim K,Joh JWdoi
10.4174/astr.2020.99.3.180subject
Has Abstractpub_date
2020-09-01 00:00:00pages
180-187issue
3eissn
2288-6575issn
2288-6796journal_volume
99pub_type
杂志文章abstract:Purpose:The anatomical variations of the thyroid gland including separate thyroidal remnant at the thyrothymic area are of significance during thyroid surgery for "total" thyroidectomy, and for recurrent goitre. In the present study, we aimed to detect the separate rests of thyroidal tissue in the thyrothymic region. ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.98.3.111
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:We aimed to develop an effective system for surgical site infection (SSI) surveillance and examine the current domestic state of SSIs for common abdominal surgeries in Korea. METHODS:The Korean Surgical Site Infection Surveillance (KOSSIS) program was developed as an SSI surveillance system. A prospective mult...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.3.119
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to find risk factors for early recurrence (ER) and early death (ED) after liver resection for colorectal cancer liver metastasis (CRCLM). METHODS:Between May 1990 and December 2011, 279 patients underwent liver resection for CRCLM at Korea University Medical Center. They were assigned...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.90.5.257
更新日期:2016-05-01 00:00:00
abstract::[This corrects the article on p. 106 in vol. 88, PMID: 25692122.]. ...
journal_title:Annals of surgical treatment and research
pub_type: 已发布勘误
doi:10.4174/astr.2015.88.3.178
更新日期:2015-03-01 00:00:00
abstract:Purpose:Meckel diverticulum (MD), caused by an obliteration defect of the omphalomesenteric duct, is one of the most common congenital anomalies of small intestines. The objective of this study was to review surgical outcomes of MD and evaluate the feasibility of minimally invasive surgery (MIS) in MD. Methods:We perf...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.4.213
更新日期:2020-10-01 00:00:00
abstract:Purpose:To compare high and low inferior mesenteric artery (IMA) ligation in a large number of patients, and investigate the short-term and long-term outcomes. Methods:This retrospective study compared outcomes between high IMA ligation and low IMA ligation with dissection of lymph nodes (LNs) around the IMA origin. A...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.5.254
更新日期:2019-11-01 00:00:00
abstract:Purpose:Repeating endoscopic retrograde cholangiopancreatography (ERCP) in patients with recurrent common bile duct (CBD) stones is problematic in many ways. Choledochoduodenostomy (CDS) and choledochojejunostomy (CJS) are 2 surgical treatment options for recurrent CBD stones, and each has different advantages and disa...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.6.329
更新日期:2020-12-01 00:00:00
abstract::Anastomotic leakage following rectal resection is a serious and fearful complication, and may cause presacral abscess and/or peritonitis. To our knowledge, massive hematochezia secondary to presacral abscess caused by anastomotic leakage has not yet been reported in the literature. We observed this rare and life-threa...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2015.88.4.236
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:Ultrasound-guided fine needle aspiration (US-FNA) in thyroid nodules is presently most commonly used to identify whether these nodules are benign or malignant. However, atypical or follicular lesions of undetermined significance (AUS/FLUS), as categorized in the Bethesda System for reporting the results of FNA,...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.90.4.201
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:The aim of our study is to evaluate the effects of administration of perioperative supplemental oxygen on anastomoses. METHODS:Forty male Wistar albino rats were used in the study and randomized into 4 groups. Ischemia-reperfusion models were built in groups 3 and 4. Jejunojejunostomy was performed in all rats...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.89.1.17
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:Trauma team activation (TTA) has been shown to have fundamental impact on trauma patients' outcomes. The purpose of this study was to evaluate the short-term outcomes of use of a new TTA protocol in the management of major trauma patients who underwent exploratory laparotomy. METHODS:The medical records of tra...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.87.6.319
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:To investigate the feasibility and safety of solo surgery with single-port laparoscopic appendectomy, which is termed herein solo-SPLA (solo-single-port laparoscopic appendectomy). METHODS:This study prospectively collected and retrospectively analyzed data from patients who had undergone either non-solo-SPLA ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.90.3.164
更新日期:2016-03-01 00:00:00
abstract:Purpose:Preoperative chemoradiation therapy (CRT) has become the standard treatment for patients with locally advanced rectal cancer, 15%-30% of patients still progress while being treated with CRT. The aim of this study was to identify as important biomarker of poor response and evaluate the mechanism associated with ...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2019.97.2.83
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:Little is known about the clinicopathological features of early mucinous gastric carcinoma (MGC). The purpose of this study was to compare the clinicopathological features and prognosis between patients with early MGC and those with early nonmucinous gastric carcinoma (NMGC). METHODS:We reviewed the records of...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.87.1.5
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:Management of appendicitis in children has always been an issue in pediatric surgery. Both diagnostic methods and treatment vary significantly among medical centers, and little consensus exists in many aspects of the care for patients with appendicitis. Here, we assessed the value of drain insertion after appen...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.6.341
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:To identify the correlation of the model for end-stage liver disease (MELD) scores with the assessment of the risk of hepatic function after hemihepatectomy in patients with hepatocellular carcinoma (HCC) related to hepatitis B virus (HBV). METHODS:A case-control study was performed based on data for 141 conse...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.86.3.122
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To analyze the benefit and feasibility of this procedure compared with those of open method. METHODS:Abdominal procedure includes laparoscopic gastric mobilization, celiac axis lymph node dissection, formation of the gastric tube, and pyloromyotomy. The actual procedure performed during open surgery is the sam...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.89.3.117
更新日期:2015-09-01 00:00:00
abstract:Purpose:Given the long history of investigation into cancer and its relevance to the lymph node (LN), it would be meaningful to plot the trends of research on cancer-related LN. Methods:Queries such as "cancer," "lymph node," and "cancer and lymph node" were submitted to PubMed to collect articles on cancer and LN pub...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2020.99.5.305
更新日期:2020-11-01 00:00:00
abstract::The majority of malignant melanomas in the small intestine are metastases from primary cutaneous lesions, it can also develop as a primary mucosal tumor in the gastrointestinal tract. In this report, we present rare cases of primary small bowel melanoma and review the current literature. A 78-year-old male presented w...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2018.94.5.274
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:This study aimed to compare the learning curves and early postoperative outcomes for conventional laparoscopic (CL) and single incision laparoscopic (SIL) right hemicolectomy (RHC). METHODS:This retrospective study included the initial 35 cases in each group. Learning curves were evaluated by the moving averag...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.5.269
更新日期:2015-05-01 00:00:00
abstract:PURPOSE:The authors evaluate the prevalence of malnutrition and its effect on the postoperative morbidity of patients after surgery for colorectal cancer. METHODS:Three hundred fifty-two patients were enrolled prospectively. Nutritional risk screening 2002 (NRS 2002) score was calculated through interview with patient...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2014.86.4.206
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:Recently, the number of elderly patients has increased due to a longer life expectancy. Among these elderly patients, more octogenarians will be diagnosed with major hepatobiliary pancreatic (HBP) diseases. Therefore, we need to evaluate the safety and risk factors of major HBP surgery in patients older than 80...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2016.91.6.288
更新日期:2016-12-01 00:00:00
abstract::Coil migration is an extremely rare but hazardous complication of aneurysmal coil embolization. Only 1 case report has described coil migration following endovascular exclusion to gastrointestinal (GI) tract. We report the experience of a case of colon penetration caused by embolization coil placed for internal iliac ...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2017.92.6.440
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:Severe local and systemic tissue damage called ischemia/reperfusion (IR) injury occurs during the period of reperfusion. Free oxygen radicals and proinflammatory cytokines are responsible for reperfusion injury. IL-18 binding protein (IL-18BP) is a natural inhibitor of IL-18. The balance between IL-18 and IL-18...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.88.2.92
更新日期:2015-02-01 00:00:00
abstract::Pediatric arterial aneurysm is rare disease. Among them, idiopathic-congenital arterial aneurysm is extremely rare. This is a case report of right common iliac artery idiopathic aneurysm with absence of right external iliac artery. A 4-year-old girl who had been complaining of intermittent abdominal pain since 2 years...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2016.91.5.265
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:The postoperative treatment after appendectomy is usually decided on the basis of the surgeons' intraoperative findings. Comparatively, the pathologic diagnosis of appendicitis is confirmed several days after the surgery; therefore, it usually does not affect the postoperative treatment strategy. The aim of thi...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2017.93.1.43
更新日期:2017-07-01 00:00:00
abstract:PURPOSE:This study aimed to determine the mortality rate in patients with severe trauma and the risk factors for trauma mortality based on 3 years' data in a regional trauma center in Korea. METHODS:We reviewed the medical records of severe trauma patients admitted to Ajou University Hospital with an Injury Severity S...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2015.89.4.215
更新日期:2015-10-01 00:00:00
abstract::We present the case of young female patient presenting with acute onset abdominal pain. Abdominopelvic CT revealed herniation through the foramen of Winslow. The patient was transferred to our hospital and underwent laparoscopic exploration. Though spontaneous reduction was detected, segmental resection of the impacte...
journal_title:Annals of surgical treatment and research
pub_type:
doi:10.4174/astr.2017.92.2.113
更新日期:2017-02-01 00:00:00
abstract:Purpose:Spontaneous gastrointestinal perforations (SGIPs; not associated with injury or disease) occur rarely in pediatric patients. This study aimed to define age-specific features associated with SGIPs in pediatric patients. Methods:Retrospectively reviewed the clinical data of children (before adolescence) who rece...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2018.95.3.141
更新日期:2018-09-01 00:00:00
abstract:Purpose:Recently a controversy has arisen about so-called "ghost surgery" practices, and people have voiced their opinions for legal sanction against such practices, which clearly undermine the foundation of medical ethics. However, there has been a lack of legal basis for punishing those actions. The present study aim...
journal_title:Annals of surgical treatment and research
pub_type: 杂志文章
doi:10.4174/astr.2018.94.4.167
更新日期:2018-04-01 00:00:00