Timeliness of vaccination in infants followed by primary-care pediatricians in France.

abstract：:Three phase II randomized trials evaluated the safety/immunogenicity of two formulations of live-attenuated tetravalent dengue virus (TDEN) vaccine in dengue-endemic (Puerto Rico, Thailand) and non-endemic (US) regions (NCT00350337/NCT00370682/NCT00468858). We describe cell-mediated immune (CMI) responses; safety and ...

journal_title：Human vaccines & immunotherapeutics

authors： Moris P,Bauer KM,Currier JR,Friberg H,Eckels KH,Esquilin IO,Gibbons RV,Innis BL,Jarman RG,Simasathien S,Sun P,Thomas SJ,Watanaveeradej V

更新日期：2019-01-01 00:00:00

abstract：:In the clinical trials of the quadrivalent human papillomavirus (qHPV) vaccine, antibodies were measured by a competitive Luminex immunoassay (HPV-4 cLIA). A nine-valent HPV (9vHPV) vaccine targeting the types in the qHPV vaccine (HPV6/11/16/18), as well as 5 of the next most frequent HPV types found in cervical cance...

journal_title：Human vaccines & immunotherapeutics

authors： Roberts C,Green T,Hess E,Matys K,Brown MJ,Haupt RM,Luxembourg A,Vuocolo S,Saah A,Antonello J

更新日期：2014-01-01 00:00:00

abstract：:Vaccination is an indisputable intervention that has tremendously mitigated the global burden of vaccine-preventable diseases (VPDs). The number of armed conflicts globally seems to be at an all-time high, with devastating effects on vaccination coverage. This paper will examine how armed conflicts affect childhood va...

journal_title：Human vaccines & immunotherapeutics

authors： Ngo NV,Pemunta NV,Muluh NE,Adedze M,Basil N,Agwale S

更新日期：2020-06-02 00:00:00

abstract：:Although immunotherapies have been employed for many decades, immune checkpoint inhibitors have only recently entered the oncologic landscape. Avelumab is a fully human monoclonal antibody that blocks the interaction between PD-L1 on tumor cells and PD-1 on T cells, thereby inhibiting immunosuppression in the tumor mi...

journal_title：Human vaccines & immunotherapeutics

authors： Collins JM,Gulley JL

更新日期：2019-01-01 00:00:00

abstract：:Pregnant women are risk group for influenza infection. Results of new subunit vaccines application have not been studied enough. Prospective, randomized, open-label comparative study of subunit (Agrippal) and polymeric subunit (Grippol plus) vaccines. 42 pairs of mothers-infants were participated in the study. Protect...

journal_title：Human vaccines & immunotherapeutics

authors： Kostinov MP,Cherdantsev AP,Kuselman AI,Akhmatova NK,Kostinova AM,Deryabina EV,Demina EO,Kostinov AM

更新日期：2018-01-01 00:00:00

abstract：:Psoriasis is a chronic, immune skin disease associated with significant morbidity. Development of psoriasis is influenced by numerous genes, one allele is HLA-CW*0602. Other genes and single nucleotide polymorphisms affect immunologic pathways and antimicrobial peptide synthesis. Dendritic cells initiate psoriasis by ...

journal_title：Human vaccines & immunotherapeutics

authors： Kaffenberger BH,Lee GL,Tyler K,Chan DV,Jarjour W,Ariza ME,Williams MV,Wong HK

更新日期：2014-01-01 00:00:00

abstract：:This article aims to explore the trends of monoclonal antibodies (mAbs) research and commercialization, mainly to examine the development trajectories by a contrastive exploration of successful and unsuccessful mAb. This work is based on two sets of R&D project reports, consisting of 517 discontinued mAb project repor...

journal_title：Human vaccines & immunotherapeutics

authors： Lai Y,Suo S,Wang R,Kong X,Hu Y,Tang D,Shi H,Chen S,Hu H

更新日期：2018-04-03 00:00:00

abstract：:DNA vaccination holds the potential to treat or prevent nearly any immunogenic disease, including cancer. To date, these vaccines have demonstrated limited immunogenicity in vivo due to the absence of a suitable delivery system which can protect DNA from degradation and improve transfection efficiencies in vivo. Recen...

journal_title：Human vaccines & immunotherapeutics

authors： Cole G,McCaffrey J,Ali AA,McBride JW,McCrudden CM,Vincente-Perez EM,Donnelly RF,McCarthy HO

更新日期：2017-01-02 00:00:00

abstract：:Meningococcal meningitis is caused by Neisseria meningitidis, a gram-negative, aerobic, encapsulated diplococcus. Meningococci are divided into numerous serogroups based on the composition of their capsular polysaccharide (Ps) antigens. At least 13 serogroups have been described: A, B, C, D, 29E, H, I, K, L, W-135, X,...

journal_title：Human vaccines & immunotherapeutics

authors： Verma R,Khanna P

更新日期：2012-12-01 00:00:00

abstract：:Current cancer immunotherapies predominantly rely on CD8(+) T cells to fight against tumors. However accumulative evidence showed that proinflammatory CD4(+) helper T cells are critical determinants of effective antitumor immunity. The utilization of universal tumor-reactive helper peptides from telomerase represents ...

journal_title：Human vaccines & immunotherapeutics

authors： Adotévi O,Dosset M,Galaine J,Beziaud L,Godet Y,Borg C

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Febrile seizure is the most common childhood neurological disorder, is an important health problem with potential short- and long-term complications, also leading to economic burden and increased parental anxiety about fevers and seizures occurring in their children. There are no routine recommendation to de...

journal_title：Human vaccines & immunotherapeutics

authors： Carman KB,Calik M,Karal Y,Isikay S,Kocak O,Ozcelik A,Yazar AS,Nuhoglu C,Sag C,Kilic O,Dinleyici M,Lacinel Gurlevik S,Yimenicioglu S,Ekici A,Perk P,Tosun A,Isik I,Yarar C,Arslantas D,Dinleyici EC

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The high coverage for ≥3 pertussis vaccine doses among Taiwanese children might not imply timely vaccination. Recently, resurgence of pertussis and challenges with availability of DTaP-IPV-Hib prompted this study. METHODS:In the 1996-2012 national birth cohort, we calculated the prevalence and days of under...

journal_title：Human vaccines & immunotherapeutics

authors： Huang WT,Lin HC,Yang CH

更新日期：2017-04-03 00:00:00

abstract：:Influenza vaccination is the cornerstone of prophylaxis. The regulatory authorities currently annually license vaccines based on serum antibodies directed toward the major surface glycoprotein haemagglutinin (HA). The most commonly used serological test, the haemagglutination inhibition (HI) assay utilizes red blood c...

journal_title：Human vaccines & immunotherapeutics

authors： Cox RJ

更新日期：2013-02-01 00:00:00

abstract：:Diphtheria-tetanus-pertussis (DTP) vaccine may be associated with excess female deaths. There are few studies of possible nonspecific effects of the DTP-containing vaccine Penta (DTP-hepatitis B-Haemophilus influenzae type b). We therefore investigated whether Penta vaccinations were associated with excess female deat...

journal_title：Human vaccines & immunotherapeutics

authors： Hanifi SMA,Biering-Sørensen S,Jensen AKG,Aaby P,Bhuiya A

更新日期：2020-06-23 00:00:00

abstract：:One combined measles-mumps-rubella (MMR) vaccine without Human Serum Albumin (HSA) is currently licensed in the USA (M-M-R II; Merck, USA) and another has been developed (Priorix™ [MMR-RIT, GSK, Belgium]). In this follow-up study, children from USA or Puerto Rico, who had received one dose of M-M-R II or MMR-RIT at 12...

journal_title：Human vaccines & immunotherapeutics

authors： Berry AA,Abu-Elyazeed R,Diaz-Perez C,Mufson MA,Harrison CJ,Leonardi M,Twiggs JD,Peltier C,Grogg S,Carbayo A,Shapiro S,Povey M,Baccarini C,Innis BL,Henry O

更新日期：2017-07-03 00:00:00

abstract：:Zika is an arboviral illness caused by infection with the Zika flavivirus. Transmission most commonly occurs during a feeding event involving an infected Aedes mosquito or vertical transmission between an infected mother to her fetus. Infection outcomes range from asymptomatic to devastating neurologic injuries in chi...

journal_title：Human vaccines & immunotherapeutics

authors： Thomas SJ,Barrett A

更新日期：2020-10-02 00:00:00

abstract：:The human commensal Staphylococcus aureus (SA) is a leading cause of skin/soft tissue and surgical-site infections, and bacteremia. Functional antibodies and T-cell-mediated immunity, particularly Th1/Th17 responses, are thought to mediate protection. Vaccine development may be hindered by modulation of vaccine-induce...

journal_title：Human vaccines & immunotherapeutics

authors： Ferraro A,Buonocore SM,Auquier P,Nicolas I,Wallemacq H,Boutriau D,van der Most RG

更新日期：2019-01-01 00:00:00

abstract：:Italy was one of the first countries in the world to introduce a routine vaccination program against HBV for newborns and 12-y-old children. From a clinical point of view, such strategy was clearly successful. The objective of our study was to verify whether, at 20 y from its implementation, hepatitis B universal vacc...

journal_title：Human vaccines & immunotherapeutics

authors： Boccalini S,Taddei C,Ceccherini V,Bechini A,Levi M,Bartolozzi D,Bonanni P

更新日期：2013-05-01 00:00:00

abstract：:There is currently a lack of sufficient data on human papillomavirus (HPV)-attributable cervical carcinoma in China. Accordingly, we aimed to determine the prevalence and genotype distribution of HPV among women with cervical lesions in Shenzhen, in order to evaluate the potential benefit of HPV vaccination programs a...

journal_title：Human vaccines & immunotherapeutics

authors： Mai Q,Yang X,Cheng H,Wu G,Wu Z

更新日期：2020-09-22 00:00:00

abstract：:Rotavirus gastroenteritis accounts for an estimated 130,000 GP consultations and 13,000 hospitalisations for children under 5 y old each year in England and Wales. In July 2013, an oral live attenuated rotavirus vaccine (Rotarix®) was introduced into the UK infant immunisation program as a 2 dose schedule at 2 and 3 m...

journal_title：Human vaccines & immunotherapeutics

authors： Inns T,Trindall A,Dunling-Hall S,Shankar AG

更新日期：2016-04-02 00:00:00

abstract：:Pertussis is a highly contagious respiratory disease caused by Bordetella pertussis. However, after the introduction of the whole-cell pertussis vaccine (wP), the annual incidence rates of the disease progressively declined. Despite this result, the inclusion of wP in the national immunization schedule of infants and ...

journal_title：Human vaccines & immunotherapeutics

authors： Esposito S,Principi N

更新日期：2018-01-01 00:00:00

abstract：:Influenza vaccination aims at reducing the incidence of serious disease, complications and death among those with the most risk of severe influenza disease. Influenza vaccine effectiveness (VE) through sentinel surveillance data from the PIDIRAC program (Daily Acute Respiratory Infection Surveillance of Catalonia) dur...

journal_title：Human vaccines & immunotherapeutics

authors： Torner N,Martínez A,Basile L,Marcos MA,Antón A,Mar Mosquera M,Isanta R,Cabezas C,Jané M,Domínguez A,Program Of Catalonia TP

更新日期：2015-01-01 00:00:00

abstract：:Polio is an acute viral disease that is still endemic in Pakistan. The polio vaccination program is facing many challenges that result in an increased number of new cases. The success of polio vaccination has been threatened in different parts of Pakistan. In the past, the immunization program was affected by differen...

journal_title：Human vaccines & immunotherapeutics

authors： Ahmad T,Khan M,Musa TH,Hui J

更新日期：2020-06-02 00:00:00

abstract：:The main causes of secondary immunodeficiency at a pediatric age include infectious diseases (mainly HIV infection), malignancies, haematopoietic stem cell or solid organ transplantation and autoimmune diseases. Children with secondary immunodeficiency have an increased risk of severe infectious diseases that could be...

journal_title：Human vaccines & immunotherapeutics

authors： Esposito S,Prada E,Lelii M,Castellazzi L

更新日期：2015-01-01 00:00:00

abstract：:Typhax is an investigational typhoid fever vaccine candidate that was GMP manufactured applying Protein Capsular Matrix Vaccine (PCMV) technology. It consists of Vi polysaccharide antigen, derived from S. Typhi, non-covalently entrapped in a glutaraldehyde catalyzed cross-linked α-poly-L-lysine and CRM197 protein matr...

journal_title：Human vaccines & immunotherapeutics

authors： Griffin TJ 4th,Thanawastien A,Cartee RT,Mekalanos JJ,Killeen KP

更新日期：2019-01-01 00:00:00

abstract：:Immunogenicity and safety of ACWY-TT compared with licensed ACWY polysaccharide vaccine (MenPS) in healthy adults, and lot-to-lot consistency of three ACWY-TT lots were evaluated in a phase 3, open, controlled study. Adults aged 18-55 y were randomized to receive ACWY-TT (one of three lots) or MenPS. Serum bactericida...

journal_title：Human vaccines & immunotherapeutics

authors： Dbaibo G,Macalalad N,Aplasca-De Los Reyes MR,Dimaano E,Bianco V,Baine Y,Miller J

更新日期：2012-07-01 00:00:00

abstract：:A universal vaccine that provides long-lasting protection from both epidemic and pandemic influenza viruses remains the "holy grail" of influenza vaccine research. Though virus neutralization assays are the current benchmark of measuring vaccine effectiveness, it is clear that Fc-receptor functions can drastically imp...

journal_title：Human vaccines & immunotherapeutics

authors： Jegaskanda S,Vanderven HA,Wheatley AK,Kent SJ

更新日期：2017-06-03 00:00:00

abstract：:Previously we showed that 65-kDa Mycobacterium leprae heat shock protein (Hsp65) is a target for the development of a tuberculosis vaccine. Here we evaluated peripheral blood mononuclear cells (PBMC) from healthy individuals or tuberculosis patients stimulated with two forms of Hsp65 antigen, recombinant DNA that enco...

journal_title：Human vaccines & immunotherapeutics

authors： Wowk PF,Franco LH,Fonseca DMD,Paula MO,Vianna ÉDSO,Wendling AP,Augusto VM,Elói-Santos SM,Teixeira-Carvalho A,Silva FDC,Vinhas SA,Martins-Filho OA,Palaci M,Silva CL,Bonato VLD

更新日期：2017-05-04 00:00:00

abstract：:Cancer immunotherapy has seen a tremendous number of failures and only few recent regulatory successes. This review is a first in a series dedicated to evaluate the status of current global clinical pipeline for cancer vaccines. Apart from specific areas of medical need which can be addressed by cancer vaccines, the a...

journal_title：Human vaccines & immunotherapeutics

authors： Kudrin A,Hanna MG Jr

更新日期：2012-08-01 00:00:00

abstract：:Anti-vaccination movement has existed as long as the vaccines themselves, but its mode of action and social influences evolved over time. Such attitude with no doubt has negative impact on vaccination rates and eradication of infectious diseases. In this study, we used an online survey to examine vaccination attitudes...

journal_title：Human vaccines & immunotherapeutics

authors： Zarobkiewicz MK,Zimecka A,Zuzak T,Cieślak D,Roliński J,Grywalska E

更新日期：2017-11-02 00:00:00