Immunization of children with secondary immunodeficiency.

abstract：:Immunotherapy shows promise for positively changing the landscape of the management of many advanced solid tumors, including gastrointestinal (GI) malignancies. Many of these developments have been focused on vaccine-based, monoclonal antibody therapies and more recently, checkpoint inhibitors, although many small mol...

journal_title：Human vaccines & immunotherapeutics

authors： Murphy AG,Zheng L

更新日期：2015-01-01 00:00:00

abstract：:Purpose: Gaps remain in the public's knowledge of the human papillomavirus (HPV). We assessed racial/ethnic and gender disparities in knowledge and awareness of HPV and the HPV vaccine among US adults. METHODS:Data from the Health Information National Trends Survey 4 Cycle 3 (September - December 2013) and Cycle 4 (A...

journal_title：Human vaccines & immunotherapeutics

authors： Adjei Boakye E,Tobo BB,Rojek RP,Mohammed KA,Geneus CJ,Osazuwa-Peters N

更新日期：2017-11-02 00:00:00

abstract：:Unvaccinated animal science and veterinary students are at risk of Q fever, a vaccine-preventable zoonotic disease transmitted from animals to humans. We investigated students' perspectives on Q fever prevention using a One Health approach combining animal, human and environmental health. Animal science and veterinary...

journal_title：Human vaccines & immunotherapeutics

authors： Rahaman MR,Milazzo A,Marshall H,Chaber AL,Bi P

更新日期：2020-11-12 00:00:00

abstract：:The programmed cell death protein 1 (PD1) is one of the checkpoints that regulates the immune response. Ligation of PD1 with its ligands PDL1 and PDL2 results in transduction of negative signals to T-cells. PD1 expression is an important mechanism contributing to the exhausted effector T-cell phenotype. The expression...

journal_title：Human vaccines & immunotherapeutics

authors： Kwok G,Yau TC,Chiu JW,Tse E,Kwong YL

更新日期：2016-11-01 00:00:00

abstract：:Hepatitis E virus (HEV) infection is one of the main causes of acute hepatitis worldwide. A recombinant hepatitis E vaccine, HEV 239, has been licensed in China for immunizing adults of 16 y old and above. The vaccine antigen contains pORF2 aa 368 - 606 of the HEV genotype 1 expressed in E. coli. The quality of the va...

journal_title：Human vaccines & immunotherapeutics

authors： Li SW,Zhao Q,Wu T,Chen S,Zhang J,Xia NS

更新日期：2015-01-01 00:00:00

abstract：:Changing epidemiology of Hepatitis A virus (HAV) has led to an increased susceptibility of adolescents and adults to the infection. Vaccination can remarkably reduce the incidence and associated morbidity of HAV infection. This review is focused on the safety and efficacy of H2 strain derived live attenuated Hepatitis...

journal_title：Human vaccines & immunotherapeutics

authors： Rao S,Mao JS,Motlekar S,Fangcheng Z,Kadhe G

更新日期：2016-12-01 00:00:00

abstract：:Previously, we have shown that DNA prime-protein boost is effective in eliciting neutralizing antibodies (NAb) against randomly selected HIV-1 isolates. Given the genetic diversity of HIV-1 viruses and the unique predominant subtypes in different geographic regions, it is critical to test the DNA prime-protein boost a...

journal_title：Human vaccines & immunotherapeutics

authors： Zhang M,Zhang L,Zhang C,Hong K,Shao Y,Huang Z,Wang S,Lu S

更新日期：2012-11-01 00:00:00

abstract：:The Solid Organ Transplantation (SOT) and Haematopoietic Stem Cell Transplantation (HSCT) population is continuously increasing as a result of broader indications for transplant and improved survival. Infectious diseases, including vaccine-preventable diseases, are a significant threat for this population, primarily a...

journal_title：Human vaccines & immunotherapeutics

authors： L'Huillier AG,Kumar D

更新日期：2015-01-01 00:00:00

abstract：:Control programs for emerging influenza are in urgent need of novel therapeutic strategies to mitigate potentially devastating threats from pathogenic strains with pandemic potential. Current vaccines and antivirals have inherent limitations in efficacy, especially with rapid evolutionary changes of influenza viruses....

journal_title：Human vaccines & immunotherapeutics

authors： Berry CM

更新日期：2018-03-04 00:00:00

abstract：:Cancer immunotherapy has seen a tremendous number of failures and only few recent regulatory successes. This is a review dedicated to determine major regulatory and developmental issues around cancer immunotherapeutics. A three pillar approach should be used in setting a development path: discovery platforms and suffi...

journal_title：Human vaccines & immunotherapeutics

authors： Kudrin A

更新日期：2012-09-01 00:00:00

abstract：:Hepatitis A is a vaccine-preventable infection caused by the HA virus (HAV) with transitional to intermediate endemicity in China. An inactivated vaccine first licensed in China in 2010 (Avaxim® 80U Pediatric) is indicated for primary and booster vaccination in children from 12 months to 15 years of age. This Phase IV...

journal_title：Human vaccines & immunotherapeutics

authors： Shi N,Rasuli A,Thollot Y

更新日期：2019-01-01 00:00:00

abstract：:Rapid population aging has become a major challenge in the industrialized world and progressive aging is a key reason for making improvement in vaccination a cornerstone of public health strategy. An increase in age-related disorders and conditions is likely to be seen in the near future, and these are risk factors fo...

journal_title：Human vaccines & immunotherapeutics

authors： Esposito S,Bonanni P,Maggi S,Tan L,Ansaldi F,Lopalco PL,Dagan R,Michel JP,van Damme P,Gaillat J,Prymula R,Vesikari T,Mussini C,Frank U,Osterhaus A,Celentano LP,Rossi M,Guercio V,Gavazzi G

更新日期：2016-07-02 00:00:00

abstract：:The durable long term clinical benefits seen for certain patients treated with immunotherapy agents has suggested there is significant therapeutic potential to be derived from these agents, as shown by the increasing prominence of this treatment strategy in upcoming clinical trials. There has been a renewed interest a...

journal_title：Human vaccines & immunotherapeutics

authors： O'Sullivan Coyne G,Gulley JL

更新日期：2014-01-01 00:00:00

abstract：:Typhax is an investigational typhoid fever vaccine candidate that was GMP manufactured applying Protein Capsular Matrix Vaccine (PCMV) technology. It consists of Vi polysaccharide antigen, derived from S. Typhi, non-covalently entrapped in a glutaraldehyde catalyzed cross-linked α-poly-L-lysine and CRM197 protein matr...

journal_title：Human vaccines & immunotherapeutics

authors： Griffin TJ 4th,Thanawastien A,Cartee RT,Mekalanos JJ,Killeen KP

更新日期：2019-01-01 00:00:00

abstract：:While most pathogens infect via mucosal surfaces, most current vaccines are delivered by injection. This situation remains despite awareness of the potential benefits of mucosal delivery for inducing protection against mucosa-infecting pathogens. A major obstacle to the development of such vaccines is the paucity of s...

journal_title：Human vaccines & immunotherapeutics

authors： Timothy AA,Tokanovic A,Snibson KJ,Edwards SJ,Pearse MJ,Scheerlinck JP,Sutton P

更新日期：2015-01-01 00:00:00

abstract：:The serious consequences of influenza infection during pregnancy have been recognized for almost a century. In this article, we reviewed the evidence on the immunogenicity, safety and impact of maternal influenza immunization for both mother and child. After vaccination, pregnant women have similar protective titers o...

journal_title：Human vaccines & immunotherapeutics

authors： Sakala IG,Honda-Okubo Y,Fung J,Petrovsky N

更新日期：2016-12-01 00:00:00

abstract：:When the next pandemic emerges, will we be ready? Experts say that the number of animal to human "species jumps" is bound to increase as populations increase and the speed of travel between continents accelerates. Typical pandemic timelines no longer apply.(1) Pandemic H1N1 traveled the world in just weeks, as did SAR...

journal_title：Human vaccines & immunotherapeutics

authors： Spero D,Petrovsky N,De Groot AS

更新日期：2012-07-01 00:00:00

abstract：:Despite the long-term efficacy and immune persistence observed following HBV vaccination of infants, the need for a booster dose following infant immunization continues to be deliberated. Evidence from HBV booster dose response studies and long-term immunization program reviews are the basis for the recommendation tha...

journal_title：Human vaccines & immunotherapeutics

authors： Osiowy C

更新日期：2018-01-01 00:00:00

abstract：:Several types of human papillomavirus (HPV) are causatively associated with cervical cancer, which is the second most common cancer in women worldwide. HPV-16 and 18 are among the high risk types and responsible for HPV infection in more than 70% of the cases. The majority of cervical cancer cases occur in developing ...

journal_title：Human vaccines & immunotherapeutics

authors： Waheed MT,Gottschamel J,Hassan SW,Lössl AG

更新日期：2012-03-01 00:00:00

abstract：:Allergen-specific IgG produced by immune mothers is associated with less predisposition to allergy development in their children. This finding has been described by several groups over the last few decades, but the mechanisms by which maternal IgG can inhibit allergy development are still not fully understood. With th...

journal_title：Human vaccines & immunotherapeutics

authors： Victor JR

更新日期：2017-03-04 00:00:00

abstract：:Senate Bill 277 (SB277) eliminated nonmedical exemptions for school-entry vaccines in California, but the impact of parental vaccine knowledge, attitudes, and beliefs on vaccine decision-making has not been extensively examined within the post-SB277 context. This study generates preliminary understanding and discussio...

journal_title：Human vaccines & immunotherapeutics

authors： Holroyd TA,Howa AC,Delamater PL,Klein NP,Buttenheim AM,Limaye RJ,Proveaux TM,Omer SB,Salmon DA

更新日期：2020-11-24 00:00:00

abstract：:Adjuvants produce complex, but often subtle, effects on vaccine-induced immune responses that, nonetheless, play a critical role in vaccine efficacy. In-depth profiling of vaccine-induced cytokine, cellular, and antibody responses ("immunoprofiling") combined with machine-learning holds the promise of identifying adju...

journal_title：Human vaccines & immunotherapeutics

authors： Chaudhury S,Duncan EH,Atre T,Dutta S,Spring MD,Leitner WW,Bergmann-Leitner ES

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Compare immune persistence from one dose of each of 3 different hepatitis A vaccines when given to school-age children: a domestic, live attenuated hepatitis A vaccine (H2 vaccine); a domestic inactivated hepatitis A vaccine (Healive®); and an imported, inactivated hepatitis A vaccine (Havrix®),. METHODS:Sch...

journal_title：Human vaccines & immunotherapeutics

authors： Zhang X,An J,Tu A,Liang X,Cui F,Zheng H,Tang Y,Liu J,Wang X,Zhang N,Li H

更新日期：2016-09-01 00:00:00

abstract：:The prevalence of seasonal allergic rhinitis in the western world is high and increasing. Besides considerably affecting physical and psychosocial aspects of patients' lives, allergic rhinitis is often associated with allergic asthma and may aggravate this condition over time. Specific immunotherapy is currently the o...

journal_title：Human vaccines & immunotherapeutics

authors： Rosewich M,Lee D,Zielen S

更新日期：2013-07-01 00:00:00

abstract：:Following the introduction of universal immunization against rotavirus, concerns were raised regarding pathogen-replacement of rotavirus by norovirus. The study aim was to examine the incidence and characteristics and norovirus gastroenteritis before and after the introduction of universal rotavirus immunization in Is...

journal_title：Human vaccines & immunotherapeutics

authors： Muhsen K,Kassem E,Rubenstein U,Goren S,Ephros M,Shulman LM,Cohen D

更新日期：2019-01-01 00:00:00

abstract：:SARS-CoV-2, the virus causing COVID-19, is a single-stranded RNA virus belonging to the order Nidovirales, family Coronaviridae, and subfamily Coronavirinae. SARS-CoV-2 entry to cellsis initiated by the binding of the viral spike protein (S) to its cellular receptor. The roles of S protein in receptor binding and memb...

journal_title：Human vaccines & immunotherapeutics

authors： Shahrajabian MH,Sun W,Cheng Q

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:In an era of hesitance to use vaccines, the importance of effective communication for increasing vaccine acceptance is well known. This study aimed to assess the impact of a three-day residential course concerning empathy and counselling abilities on patients' ratings of the level of empathy of physicians an...

journal_title：Human vaccines & immunotherapeutics

authors： Maurici M,Arigliani M,Dugo V,Leo C,Pettinicchio V,Arigliani R,Franco E

更新日期：2019-01-01 00:00:00

abstract：:Respiratory infections caused by Pseudomonas aeruginosa are a major clinical problem globally, particularly for patients with chronic pulmonary disorders, such as those with cystic fibrosis (CF), non-CF bronchiectasis (nCFB) and severe chronic obstructive pulmonary disease (COPD). In addition, critically ill and immun...

journal_title：Human vaccines & immunotherapeutics

authors： Grimwood K,Kyd JM,Owen SJ,Massa HM,Cripps AW

更新日期：2015-01-01 00:00:00

abstract：:Background: Rubella continues to be a leading cause of vaccine-preventable congenital birth defects and permanent organ damage, especially in developing countries. For women who are infected with the rubella virus (RV) before conception or during the first trimester of pregnancy, the unborn child has up to a 90% proba...

journal_title：Human vaccines & immunotherapeutics

authors： Kassa ZY,Hussen S,Asnake S

更新日期：2020-10-02 00:00:00

abstract：:Vaccines dramatically reduce infection-related morbidity and mortality. Determining factors that modulate the host response is key to rational vaccine design and demands unsupervised analysis. To longitudinally resolve influenza-specific humoral immune response dynamics we constructed vaccine response profiles of infl...

journal_title：Human vaccines & immunotherapeutics

authors： Berger CT,Greiff V,Mehling M,Fritz S,Meier MA,Hoenger G,Conen A,Recher M,Battegay M,Reddy ST,Hess C

更新日期：2015-01-01 00:00:00