Plant-derived vaccines: an approach for affordable vaccines against cervical cancer.

abstract：:Pneumococci are capable of vaccine escape by genetic recombination at the targeted capsular locus, significantly reducing long-term vaccine effectiveness. Recently, efforts have been redirected to understanding pneumococcal biology related to potential next-generation vaccine candidates. A variety of serotype-independ...

journal_title：Human vaccines & immunotherapeutics

authors： Abry MF,Kimenyi KM,Osowo FO,Odhiambo WO,Sewe SO,Kulohoma BW

更新日期：2015-01-01 00:00:00

abstract：:Background: The expansion of available vaccines in recent years has increased the overall costs of the vaccine program and put pressure on providers responsible for vaccination. In England in 2016-17, GP practices responsible for vaccinating their local population were paid £227 million. However, the costs to general ...

journal_title：Human vaccines & immunotherapeutics

authors： Crocker-Buque T,Mohan K,Ramsay M,Edelstein M,Mounier-Jack S

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:In China, Hib vaccine is a private-sector vaccine that is an option for parents to select to give to their children; it must be paid for out-of-pocket because it is not included in the government's Expanded Program on Immunization (EPI). We evaluated utilization patterns of Hib vaccine to provide evidence in ...

journal_title：Human vaccines & immunotherapeutics

authors： Li Y,Yue C,Wang Y,Zhu X,Martin K,Scherpbier RW,Liu J,Wang Z,Ma Y,Cheng H,Zhang Z,Wang Q,Li H,Xie S,Xiao Q,Wang H,An Z

更新日期：2018-04-03 00:00:00

abstract：:Cellular immunotherapy can be an effective adjuvant treatment for multiple myeloma (MM), as demonstrated by induction of durable remissions after allogeneic stem cell transplantation. However, anti-myeloma immunity is often hampered by suppressive mechanisms in the tumor micro-environment resulting in relapse or disea...

journal_title：Human vaccines & immunotherapeutics

authors： Roeven MW,Hobo W,Schaap N,Dolstra H

更新日期：2014-01-01 00:00:00

abstract：:This study aims to quantify clinical and economic burden of rotavirus (RV) infection pre- and post-vaccine introduction in commercially insured and Medicaid populations. Beneficiaries with continuous enrollment for ≥6 months while <5 years of age were identified separately in commercial (2000-2010) and Medicaid (2002-...

journal_title：Human vaccines & immunotherapeutics

authors： Krishnarajah G,Demissie K,Lefebvre P,Gaur S,Sheng Duh M

更新日期：2014-01-01 00:00:00

abstract：:Pregnant women are risk group for influenza infection. Results of new subunit vaccines application have not been studied enough. Prospective, randomized, open-label comparative study of subunit (Agrippal) and polymeric subunit (Grippol plus) vaccines. 42 pairs of mothers-infants were participated in the study. Protect...

journal_title：Human vaccines & immunotherapeutics

authors： Kostinov MP,Cherdantsev AP,Kuselman AI,Akhmatova NK,Kostinova AM,Deryabina EV,Demina EO,Kostinov AM

更新日期：2018-01-01 00:00:00

abstract：:Dynamically changing social situation associated with migrations, increasing freedom rights, popularity of anti-vaccine movements and the resulting from that decrease in herd immunity, forces the medical society and the governments of various countries to reflect on the attitude toward vaccinations. Issues of freedoms...

journal_title：Human vaccines & immunotherapeutics

authors： Patryn RK,Zagaja A

更新日期：2016-08-02 00:00:00

abstract：:Current cancer immunotherapies predominantly rely on CD8(+) T cells to fight against tumors. However accumulative evidence showed that proinflammatory CD4(+) helper T cells are critical determinants of effective antitumor immunity. The utilization of universal tumor-reactive helper peptides from telomerase represents ...

journal_title：Human vaccines & immunotherapeutics

authors： Adotévi O,Dosset M,Galaine J,Beziaud L,Godet Y,Borg C

更新日期：2013-05-01 00:00:00

abstract：:Monoclonal antibody preparations have demonstrated considerable clinical utility in the treatment of specific malignancies, as well as inflammatory and infectious diseases. Antibodies are conventionally delivered by passive administration, typically requiring costly large-scale laboratory development and production. A...

journal_title：Human vaccines & immunotherapeutics

authors： Muthumani K,Flingai S,Wise M,Tingey C,Ugen KE,Weiner DB

更新日期：2013-10-01 00:00:00

abstract：:We report the findings of three randomized, double-blind, placebo-controlled Phase I studies undertaken to support licensure of the liquid formulation of the human G1P[8] rotavirus (RV) vaccine (RIX4414; GlaxoSmithKline Biologicals SA) in China. Healthy adults aged 18-45 y (n=48) and children aged 2-6 y (n=50) receive...

journal_title：Human vaccines & immunotherapeutics

authors： Li RC,Li YP,Mo ZJ,Luo D,Huang T,Kong JL,Wang LH,Song NS,Liu A,Zhang H,Liao X,Karkada N,Han HH

更新日期：2013-08-01 00:00:00

abstract：:Pertussis is one of the most prevalent vaccine-preventable diseases worldwide. The true infection rate is significantly higher than the reported incidence rate. An increased prevalence of pertussis in older populations has been found, mainly caused by waning immunity after vaccination. Vaccine-induced immunity differs...

journal_title：Human vaccines & immunotherapeutics

authors： Chen Z,He Q

更新日期：2017-04-03 00:00:00

abstract：:Psoriasis is a chronic, immune skin disease associated with significant morbidity. Development of psoriasis is influenced by numerous genes, one allele is HLA-CW*0602. Other genes and single nucleotide polymorphisms affect immunologic pathways and antimicrobial peptide synthesis. Dendritic cells initiate psoriasis by ...

journal_title：Human vaccines & immunotherapeutics

authors： Kaffenberger BH,Lee GL,Tyler K,Chan DV,Jarjour W,Ariza ME,Williams MV,Wong HK

更新日期：2014-01-01 00:00:00

abstract：:Hepatitis B vaccine is the most effective strategy to control hepatitis B virus (HBV) infection and disease. It is considered that an anti-HBs (antibodies against HBV surface antigen) titer >10 mIU/ml, measured shortly after a complete vaccination schedule, provides protection against infection. Approximately 4-10% of...

journal_title：Human vaccines & immunotherapeutics

authors： Cassaniti I,Calarota SA,Adzasehoun KM,Chiesa A,Comolli G,Parea M,Baldanti F

更新日期：2016-11-01 00:00:00

abstract：:The study of influenza virus evolution in humans has revealed a significant role of glycosylation profile alterations in the viral glycoproteins - hemagglutinin (HA) and neuraminidase (NA), in the emergence of both seasonal and pandemic strains. Viral antigenic drift can modify the number and location of glycosylation...

journal_title：Human vaccines & immunotherapeutics

authors： Cruz E,Cain J,Crossett B,Kayser V

更新日期：2018-03-04 00:00:00

abstract：:Following the introduction of universal immunization against rotavirus, concerns were raised regarding pathogen-replacement of rotavirus by norovirus. The study aim was to examine the incidence and characteristics and norovirus gastroenteritis before and after the introduction of universal rotavirus immunization in Is...

journal_title：Human vaccines & immunotherapeutics

authors： Muhsen K,Kassem E,Rubenstein U,Goren S,Ephros M,Shulman LM,Cohen D

更新日期：2019-01-01 00:00:00

abstract：:DNA vaccination holds the potential to treat or prevent nearly any immunogenic disease, including cancer. To date, these vaccines have demonstrated limited immunogenicity in vivo due to the absence of a suitable delivery system which can protect DNA from degradation and improve transfection efficiencies in vivo. Recen...

journal_title：Human vaccines & immunotherapeutics

authors： Cole G,McCaffrey J,Ali AA,McBride JW,McCrudden CM,Vincente-Perez EM,Donnelly RF,McCarthy HO

更新日期：2017-01-02 00:00:00

abstract：:This study aimed to describe the disparities in immunization coverage between National Immunization Program (NIP) vaccines and non-NIP vaccines in Yiwu and to identify potential determinants. A face-to-face interview-based questionnaire survey among 423 migrant children born from 1 June 2010 to 31 May 2013 was conduct...

journal_title：Human vaccines & immunotherapeutics

authors： Hu Y,Luo S,Tang X,Lou L,Chen Y,Guo J

更新日期：2015-01-01 00:00:00

abstract：:Ebola virus disease (EVD) has become a great threat to humans across the world in recent years. The 2014 Ebola epidemic in West Africa caused numerous deaths and attracted worldwide attentions. Since no specific drugs and treatments against EVD was available, vaccination was considered as the most promising and effect...

journal_title：Human vaccines & immunotherapeutics

authors： Wang Y,Li J,Hu Y,Liang Q,Wei M,Zhu F

更新日期：2017-01-02 00:00:00

abstract：:Previously we showed that 65-kDa Mycobacterium leprae heat shock protein (Hsp65) is a target for the development of a tuberculosis vaccine. Here we evaluated peripheral blood mononuclear cells (PBMC) from healthy individuals or tuberculosis patients stimulated with two forms of Hsp65 antigen, recombinant DNA that enco...

journal_title：Human vaccines & immunotherapeutics

authors： Wowk PF,Franco LH,Fonseca DMD,Paula MO,Vianna ÉDSO,Wendling AP,Augusto VM,Elói-Santos SM,Teixeira-Carvalho A,Silva FDC,Vinhas SA,Martins-Filho OA,Palaci M,Silva CL,Bonato VLD

更新日期：2017-05-04 00:00:00

abstract：:Influenza can be potentially fatal to vulnerable populations, particularly those in the hospital. Canada's National Advisory Committee on Immunization recommends that health-care workers (HCW) be immunized against influenza partly to avoid infecting high-risk populations. However, influenza immunization rates among HC...

journal_title：Human vaccines & immunotherapeutics

authors： Di Castri AM,Halperin DM,McPherson CM,Nunn A,Farrar-Muir H,Kwong JC,Henry B

更新日期：2020-06-02 00:00:00

abstract：:Leukemia-associated antigens such as proteinase-3 (PR3) and Wilms' tumor protein-1 (WT-1) are potential targets of T-cell responses, which can be monitored by T-cell assays within vaccination trials and after allogeneic stem cell transplantation (SCT). In chronic myeloid leukemia (CML) an aberrant cytokine profile of ...

journal_title：Human vaccines & immunotherapeutics

authors： Flörcken A,van Lessen A,Terwey TH,Dörken B,Arnold R,Pezzutto A,Westermann J

更新日期：2013-06-01 00:00:00

abstract：:The introduction of a serogroup A meningococcal conjugate vaccine in the African meningitis belt has been a remarkable success. Meningitis due to the serogroup A meningococcus, previously responsible for most epidemics, has fallen by 99% in vaccinated countries. Success must, however, not distract from the continuing ...

journal_title：Human vaccines & immunotherapeutics

authors： Stuart JM

更新日期：2018-05-04 00:00:00

abstract：:Human papillomavirus (HPV) vaccine uptake among 18-26 y old women varies by geographic region in the US. However, little is known about regional variations in vaccination among girls who are in the vaccine's targeted age groups. Regional variation in HPV vaccination among female adolescents (9-17 y old) was examined u...

journal_title：Human vaccines & immunotherapeutics

authors： Hirth JM,Rahman M,Smith JS,Berenson AB

更新日期：2014-01-01 00:00:00

abstract：:Maternal vaccination offers the opportunity to protect pregnant women and their infants against potentially serious disease. As both pregnant women and their newborns are vulnerable to severe illness, the potential public health impact of mass maternal vaccination programs is remarkable. Several high-income countries ...

journal_title：Human vaccines & immunotherapeutics

authors： Regan AK

更新日期：2016-12-01 00:00:00

abstract：:Background: Despite long standing recommendations of pneumococcal and influenza vaccination for adults age 65 years and older and wide-spread availability to vaccination services, vaccination coverage in the United states is low. We sought to explore reasons patients reportedly did not receive these vaccines.Methods: ...

journal_title：Human vaccines & immunotherapeutics

authors： Shen AK,Warnock R,Selna W,Chu S,Kelman JA

更新日期：2020-05-03 00:00:00

abstract：:Human papillomavirus is considered the causative factor for cervical cancer, which accounts for approximately 5% of the global cancer burden and more than 600,000 new cases annually that are attributable to HPV infection worldwide. The first-generation prophylactic HPV vaccines, Gardasil® and Cervarix®, were licensed ...

journal_title：Human vaccines & immunotherapeutics

authors： Zhang Z,Zhang J,Xia N,Zhao Q

更新日期：2017-10-03 00:00:00

abstract：:Variations of post-translational modifications are important for stability and in vivo behavior of therapeutic antibodies. A recombinant humanized anti-cocaine monoclonal antibody (h2E2) was characterized for heterogeneity of N-linked glycosylation and disulfide bonds. In addition, charge heterogeneity, which is parti...

journal_title：Human vaccines & immunotherapeutics

authors： Kirley TL,Norman AB

更新日期：2015-01-01 00:00:00

abstract：:Influenza, caused by the influenza virus, is a contagious acute viral respiratory disease with a high incidence rate and wide and rapid spread. Influenza-related morbidity, mortality, and hospitalization rates remain high and are increasing continuously in high-risk groups, with a significant impact on human health an...

journal_title：Human vaccines & immunotherapeutics

authors： Gao D,Yang H,Deng B,Yin G,Song W,Zhang H,Li Y

更新日期：2016-10-02 00:00:00

abstract：:Human papilloma viruses (HPVs) infect the skin and mucosal epithelium of both men and women. There are about 100 types of HPVs, which are differentiated by the genetic sequence of the outer capsid protein L1. More than 30 types of HPVs are sexually transmitted. Most cases of carcinoma of the cervix are caused by HPV. ...

journal_title：Human vaccines & immunotherapeutics

authors： Verma R,Khanna P

更新日期：2013-01-01 00:00:00

abstract：:A 9-valent HPV (9vHPV) vaccine has been developed to protect against HPV type 6/11/16/18/31/33/45/52/58-related infection and disease. Previous safety analyses from 7 clinical trials conducted in 9vHPV vaccine recipients 9-26 years of age, including comparisons of 9vHPV and quadrivalent HPV (qHPV) vaccines in girls an...

journal_title：Human vaccines & immunotherapeutics

authors： Moreira ED,Giuliano AR,de Hoon J,Iversen OE,Joura EA,Restrepo J,Van Damme P,Vandermeulen C,Ellison MC,Krick A,Shields C,Heiles B,Luxembourg A

更新日期：2018-02-01 00:00:00