Prospective randomized open-label comparative study of immunogenicity after subunit and polymeric subunit influenza vaccines administration among mothers and infants.

abstract：:Eight months after the mass immunization campaign of November 2015 against measles and rubella in the southeast of Iran, in order to evaluate the sero-immunity level of the people living in the mentioned region, a serosurvey study was performed. Using a multi-stage probability proportional to size cluster sampling, th...

journal_title：Human vaccines & immunotherapeutics

authors： Izadi S,Zahraei SM,Mokhtari-Azad T

更新日期：2018-06-03 00:00:00

abstract：:Within the past few years, several measles outbreaks have occurred in the southeast of Iran. To learn about the effectiveness of the immunization services for producing a serologic response against measles, this follow-up study was designed and implemented in the southeast of Iran. In Iran, all routine immunization se...

journal_title：Human vaccines & immunotherapeutics

authors： Zahraei SM,Izadi S,Mokhtari-Azad T

更新日期：2016-12-01 00:00:00

abstract：:Research on innate immune signaling and regulation has recently focused on pathogen recognition receptors (PRRs) and their signaling pathways. Members of PRRs sense diverse microbial invasions or danger signals, and initiate innate immune signaling pathways, leading to proinflammatory cytokines production, which, in t...

journal_title：Human vaccines & immunotherapeutics

authors： Cui J,Chen Y,Wang HY,Wang RF

更新日期：2014-01-01 00:00:00

abstract：:Individuals infected with human immunodeficiency virus (HIV) have excess risk of developing human papillomavirus (HPV)-related disease. A substantial fraction of HPV-associated cancers is caused by HPV serotypes not included in the currently available vaccines. Among healthy women, both Cervarix(®) (HPV-16/18, GlaxoSm...

journal_title：Human vaccines & immunotherapeutics

authors： Toft L,Tolstrup M,Müller M,Sehr P,Bonde J,Storgaard M,Østergaard L,Søgaard OS

更新日期：2014-01-01 00:00:00

abstract：:Cellular immunotherapy can be an effective adjuvant treatment for multiple myeloma (MM), as demonstrated by induction of durable remissions after allogeneic stem cell transplantation. However, anti-myeloma immunity is often hampered by suppressive mechanisms in the tumor micro-environment resulting in relapse or disea...

journal_title：Human vaccines & immunotherapeutics

authors： Roeven MW,Hobo W,Schaap N,Dolstra H

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The aim of the present study is to review the economic burden of varicella disease and the benefit of universal varicella vaccination in different settings pending its implementation in all Italian regions. MATERIALS AND METHODS:Research was conducted using PubMed, Scopus and ISI databases. Score quality ...

journal_title：Human vaccines & immunotherapeutics

authors： Unim B,Saulle R,Boccalini S,Taddei C,Ceccherini V,Boccia A,Bonanni P,La Torre G

更新日期：2013-09-01 00:00:00

abstract：:Dendritic cells (DCs) are known to be a set of morphology, structure and function of heterogeneous professional antigen presenting cells (APCs), as well as the strongest functional antigen presenting cells, which can absorb, process and present antigens. As the key regulators of innate and adaptive immune responses, D...

journal_title：Human vaccines & immunotherapeutics

authors： Chen P,Liu X,Sun Y,Zhou P,Wang Y,Zhang Y

更新日期：2016-03-03 00:00:00

abstract：:Vaccination directly protects vaccinated individuals, but it also has the potential for indirectly protecting the unvaccinated in a population (herd protection). Unintended negative consequences such as the re-manifestation of infection, mainly expressed as age shifts, result from vaccination programs as well. We disc...

journal_title：Human vaccines & immunotherapeutics

authors： Scarbrough Lefebvre CD,Terlinden A,Standaert B

更新日期：2015-01-01 00:00:00

abstract：:Combined therapy using chemotherapeutic drugs and immunotherapeutics offers some promise for treating patients with cancer. In this study, we evaluated whether cisplatin delivered by intratumoral (IT)-electroporation (EP) might enhance antitumor activity against established B16 melanoma and whether further addition of...

journal_title：Human vaccines & immunotherapeutics

authors： Kim H,Sin JI

更新日期：2012-11-01 00:00:00

abstract：:Rubella is a contagious viral disease, which mainly affects the fetus, if the mother is infected in the 1st trimester of her pregnancy. All adolescent girls (aged 11 to 19 y) and women of childbearing age are at risk of developing rubella. This disease is mild and self-limiting, and incubation period is 2-3 weeks. Hum...

journal_title：Human vaccines & immunotherapeutics

authors： Verma R,Khanna P,Chawla S

更新日期：2012-06-01 00:00:00

abstract：:Vaccination is an indisputable intervention that has tremendously mitigated the global burden of vaccine-preventable diseases (VPDs). The number of armed conflicts globally seems to be at an all-time high, with devastating effects on vaccination coverage. This paper will examine how armed conflicts affect childhood va...

journal_title：Human vaccines & immunotherapeutics

authors： Ngo NV,Pemunta NV,Muluh NE,Adedze M,Basil N,Agwale S

更新日期：2020-06-02 00:00:00

abstract：:The efficacy and effectiveness of influenza vaccines depend primarily on the vaccine recipient and the virus similarity to the endemic virus. Regulatory T cells (Tregs) and cytokines are known to restrict immune responses against viral infections. We conducted this study to explore the role of Tregs, cytokines, and an...

journal_title：Human vaccines & immunotherapeutics

authors： Wang SM,Tsai MH,Lei HY,Wang JR,Liu CC

更新日期：2012-09-01 00:00:00

abstract：:Hollingsworth and Isturiz (1) have raised several questions about our earlier review of the use of pneumococcal conjugate (PCV) or polysaccharide (PPV) vaccine for older adults (i.e., ≥65 y of age). (2) They begin by citing two metaanalyses published in 2009 and 2013 that concluded that prevention of pneumococcal pneu...

journal_title：Human vaccines & immunotherapeutics

authors： Fedson DS

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence of adverse events following administration of an Inactivated poliomyelitis vaccine (IPV) manufactured by Serum Institute of India Pvt. Ltd., Pune, India. METHODS:A single 0.5 ml dose of the IPV was administered intramuscularly to children attending private clinics or out-patient dep...

journal_title：Human vaccines & immunotherapeutics

authors： Sharma H,Dhere R,Parekh S,Shewale S

更新日期：2017-11-02 00:00:00

abstract：:Pertussis is a highly contagious respiratory disease caused by Bordetella pertussis. However, after the introduction of the whole-cell pertussis vaccine (wP), the annual incidence rates of the disease progressively declined. Despite this result, the inclusion of wP in the national immunization schedule of infants and ...

journal_title：Human vaccines & immunotherapeutics

authors： Esposito S,Principi N

更新日期：2018-01-01 00:00:00

abstract：:Varicella is a common vaccine-preventable disease that usually presents in children as a mild infection; however, severe complications also occur. The burden of varicella is significant in the terms of incidence, complication, and hospitalization rate related to varicella and economic disease burden. Despite the evide...

journal_title：Human vaccines & immunotherapeutics

authors： Horváth A

更新日期：2020-12-16 00:00:00

abstract：:Anflu® is a seasonal trivalent inactivated split-virion influenza vaccine manufactured by Sinovac Biotech Co., Ltd. The objectives of this study were to evaluate the safety of Anflu® (2013-14 formulation: H1N1, H3N2 and BYAM) in infants and adults and its immunogenicity and cross-reactivity against mismatched influenz...

journal_title：Human vaccines & immunotherapeutics

authors： Shen Y,Hu Y,Meng F,Du W,Li W,Song Y,Ji X,Huo L,Fu Z,Yin W

更新日期：2016-05-03 00:00:00

abstract：:The prevalence of seasonal allergic rhinitis in the western world is high and increasing. Besides considerably affecting physical and psychosocial aspects of patients' lives, allergic rhinitis is often associated with allergic asthma and may aggravate this condition over time. Specific immunotherapy is currently the o...

journal_title：Human vaccines & immunotherapeutics

authors： Rosewich M,Lee D,Zielen S

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:To evaluate the validity and reliability of a survey to identify vaccine hesitancy among parents. METHODS:Cross-sectional survey of parents of 19-35 month old children was conducted in Changxing County, Zhejiang Province, through a questionnaire developed for the survey of the vaccine hesitancy. Construct v...

journal_title：Human vaccines & immunotherapeutics

authors： Hu Y,Chen Y,Liang H,Wang Y

更新日期：2019-01-01 00:00:00

abstract：:HIV sequence diversity and the propensity of eliciting immunodominant responses targeting inessential variable regions are hurdles in the development of an effective AIDS vaccine. We developed a DNA vaccine comprising conserved elements (CE) of SIV p27Gag and HIV-1 Env and found that priming vaccination with CE DNA is...

journal_title：Human vaccines & immunotherapeutics

authors： Hu X,Lu Z,Valentin A,Rosati M,Broderick KE,Sardesai NY,Marx PA,Mullins JI,Pavlakis GN,Felber BK

更新日期：2018-01-01 00:00:00

abstract：:Several types of human papillomavirus (HPV) are causatively associated with cervical cancer, which is the second most common cancer in women worldwide. HPV-16 and 18 are among the high risk types and responsible for HPV infection in more than 70% of the cases. The majority of cervical cancer cases occur in developing ...

journal_title：Human vaccines & immunotherapeutics

authors： Waheed MT,Gottschamel J,Hassan SW,Lössl AG

更新日期：2012-03-01 00:00:00

abstract：:H5N1 influenza candidate vaccine viruses were developed using the "6+2" approach. The hemagglutinin (HA) and neuraminidase (NA) genes were derived from the popular H5N1 virus and the remaining six internal segments were derived from the A/Puerto Rico/8/34 strain (H1N1, PR8). However, some of these candidate strains ha...

journal_title：Human vaccines & immunotherapeutics

authors： Pan W,Dong Z,Meng W,Zhang W,Li T,Li C,Zhang B,Chen L

更新日期：2012-02-01 00:00:00

abstract：:Background: To assess the knowledge and attitudes of middle school students toward vaccination, we measured their understanding of vaccine safety and effectiveness, expectations for communication with heath care providers, and their desired role in the vaccination decision-making process. Methods: A cross-sectional, s...

journal_title：Human vaccines & immunotherapeutics

authors： Herman R,McNutt LA,Mehta M,Salmon DA,Bednarczyk RA,Shaw J

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Adolescents are the primary target population for human papillomavirus (HPV) vaccination. The objective of this study is to explore the acceptability of HPV vaccines and evaluate factors related to willingness to be vaccinated among Chinese adolescents. METHODS:A nation-wide survey was conducted across 14 s...

journal_title：Human vaccines & immunotherapeutics

authors： Zhang X,Wang Z,Ren Z,Li Z,Ma W,Gao X,Zhang R,Qiao Y,Li J

更新日期：2020-10-29 00:00:00

abstract：:Last decades, the number of routine childhood vaccinations has increased considerably, which consequently has led to multiple vaccine injections per consultation. Implementation of additional vaccines will probably lead to more than 2 vaccine injections per consult, which might be a barrier for parents to vaccinate th...

journal_title：Human vaccines & immunotherapeutics

authors： Kaaijk P,Kleijne DE,Knol MJ,Harmsen IA,Ophorst OJ,Rots NY

更新日期：2014-01-01 00:00:00

abstract：:Typhax is an investigational typhoid fever vaccine candidate that was GMP manufactured applying Protein Capsular Matrix Vaccine (PCMV) technology. It consists of Vi polysaccharide antigen, derived from S. Typhi, non-covalently entrapped in a glutaraldehyde catalyzed cross-linked α-poly-L-lysine and CRM197 protein matr...

journal_title：Human vaccines & immunotherapeutics

authors： Griffin TJ 4th,Thanawastien A,Cartee RT,Mekalanos JJ,Killeen KP

更新日期：2019-01-01 00:00:00

abstract：:Human papillomavirus (HPV) infection is a major cause of cervical cancer. HPV vaccine has been shown to be highly effective in preventing HPV infection, and understanding the genotypes of HPV infection can guide the utilization of HPV vaccine. This epidemiological study aimed to investigate the genotype distribution o...

journal_title：Human vaccines & immunotherapeutics

authors： Geng Y,Liu L

更新日期：2019-01-01 00:00:00

abstract：:Rapid production of influenza vaccine antigen is an important challenge when a new pandemic occurs. Production of recombinant antigens in plants is a quick, cost effective and up scalable new strategy for influenza vaccine production. In this study, we have characterized a recombinant influenza haemagglutinin antigen ...

journal_title：Human vaccines & immunotherapeutics

authors： Jul-Larsen Å,Madhun AS,Brokstad KA,Montomoli E,Yusibov V,Cox RJ

更新日期：2012-05-01 00:00:00

abstract：:One combined measles-mumps-rubella (MMR) vaccine without Human Serum Albumin (HSA) is currently licensed in the USA (M-M-R II; Merck, USA) and another has been developed (Priorix™ [MMR-RIT, GSK, Belgium]). In this follow-up study, children from USA or Puerto Rico, who had received one dose of M-M-R II or MMR-RIT at 12...

journal_title：Human vaccines & immunotherapeutics

authors： Berry AA,Abu-Elyazeed R,Diaz-Perez C,Mufson MA,Harrison CJ,Leonardi M,Twiggs JD,Peltier C,Grogg S,Carbayo A,Shapiro S,Povey M,Baccarini C,Innis BL,Henry O

更新日期：2017-07-03 00:00:00

abstract：:Background: The expansion of available vaccines in recent years has increased the overall costs of the vaccine program and put pressure on providers responsible for vaccination. In England in 2016-17, GP practices responsible for vaccinating their local population were paid £227 million. However, the costs to general ...

journal_title：Human vaccines & immunotherapeutics

authors： Crocker-Buque T,Mohan K,Ramsay M,Edelstein M,Mounier-Jack S

更新日期：2019-01-01 00:00:00