Improvement of influenza vaccine strain A/Vietnam/1194/2004 (H5N1) growth with the neuraminidase packaging sequence from A/Puerto Rico/8/34.

abstract：:Rotavirus (RV) and norovirus (NoV) are the 2 leading causes of acute viral gastroenteritis worldwide. We have developed a non-live NoV and RV vaccine candidate consisting of NoV virus-like particles (VLPs) and recombinant polymeric RV VP6 protein produced in baculovirus-insect cell expression system. Both components h...

journal_title：Human vaccines & immunotherapeutics

authors： Blazevic V,Malm M,Arinobu D,Lappalainen S,Vesikari T

更新日期：2016-03-03 00:00:00

abstract：:Influenza and pneumococcal vaccinations are recommended in the elderly to reduce life-threatening complications like sepsis. Protection may be reduced with increasing age. We aimed to assess the effectiveness of both vaccines in the elderly by performing a retrospective cohort study of 138,877 individuals aged ≥60 y i...

journal_title：Human vaccines & immunotherapeutics

authors： Rose N,Storch J,Mikolajetz A,Lehmann T,Reinhart K,Pletz MW,Forstner C,Vollmar HC,Freytag A,Fleischmann-Struzek C

更新日期：2021-01-07 00:00:00

abstract：:Tetanus, diphtheria, and acellular pertussis (Tdap) vaccination is recommended for all women during each pregnancy to prevent pertussis in young infants. However, data on the safety of this protective measure are limited and conflicting. To assess maternal and infant outcomes associated with administration of this vac...

journal_title：Human vaccines & immunotherapeutics

authors： Berenson AB,Hirth JM,Rahman M,Laz TH,Rupp RE,Sarpong KO

更新日期：2016-08-02 00:00:00

abstract：:Rotavirus gastroenteritis accounts for an estimated 130,000 GP consultations and 13,000 hospitalisations for children under 5 y old each year in England and Wales. In July 2013, an oral live attenuated rotavirus vaccine (Rotarix®) was introduced into the UK infant immunisation program as a 2 dose schedule at 2 and 3 m...

journal_title：Human vaccines & immunotherapeutics

authors： Inns T,Trindall A,Dunling-Hall S,Shankar AG

更新日期：2016-04-02 00:00:00

abstract：:Anti-vaccination movement has existed as long as the vaccines themselves, but its mode of action and social influences evolved over time. Such attitude with no doubt has negative impact on vaccination rates and eradication of infectious diseases. In this study, we used an online survey to examine vaccination attitudes...

journal_title：Human vaccines & immunotherapeutics

authors： Zarobkiewicz MK,Zimecka A,Zuzak T,Cieślak D,Roliński J,Grywalska E

更新日期：2017-11-02 00:00:00

abstract：:The immune system becomes less effective with age, and older age is associated with an increased susceptibility to diseases and reduced responses to vaccination. Furthermore, some adult populations, such as those with diabetes mellitus, are at increased risk of acute hepatitis B virus (HBV) infection. Decreasing respo...

journal_title：Human vaccines & immunotherapeutics

authors： Van Der Meeren O,Crasta P,Cheuvart B,De Ridder M

更新日期：2015-01-01 00:00:00

abstract：:Eight months after the mass immunization campaign of November 2015 against measles and rubella in the southeast of Iran, in order to evaluate the sero-immunity level of the people living in the mentioned region, a serosurvey study was performed. Using a multi-stage probability proportional to size cluster sampling, th...

journal_title：Human vaccines & immunotherapeutics

authors： Izadi S,Zahraei SM,Mokhtari-Azad T

更新日期：2018-06-03 00:00:00

abstract：:Human papillomavirus (HPV) vaccines are efficacious against HPV infections and associated lesions in women HPV-naïve at vaccination. However, vaccine efficacy (VE) against oncogenic, high-risk HPV (HR-HPV) types in women infected with any other HR-HPV type at first vaccination (baseline) remains unclear. This post-hoc...

journal_title：Human vaccines & immunotherapeutics

authors： Hu S,Xu X,Zhu F,Hong Y,Hu Y,Zhang X,Pan Q,Zhang W,Zhang C,Yang X,Yu J,Zhu J,Zhu Y,Chen F,Zhao S,Karkada N,Tang H,Bi D,Struyf F,Zhao F

更新日期：2020-11-12 00:00:00

abstract：:Rotavirus is the most common cause of diarrhea leading to hospitalization in young children. Rotavirus vaccines are available in Canada but have not been introduced in all provinces. In a controlled trial, 2 study sites (Prince Edward Island and the Capital District Health Authority (District 9, Nova Scotia) introduce...

journal_title：Human vaccines & immunotherapeutics

authors： Sanford C,Langley JM,Halperin SA,Zelman M,Mvrvp

更新日期：2015-01-01 00:00:00

abstract：:Control programs for emerging influenza are in urgent need of novel therapeutic strategies to mitigate potentially devastating threats from pathogenic strains with pandemic potential. Current vaccines and antivirals have inherent limitations in efficacy, especially with rapid evolutionary changes of influenza viruses....

journal_title：Human vaccines & immunotherapeutics

authors： Berry CM

更新日期：2018-03-04 00:00:00

abstract：:The development of a successful vaccine, which should elicit a combination of humoral and cellular responses to control or prevent infections, is the first step in protecting against infectious diseases. A vaccine may protect against bacterial, fungal, parasitic, or viral infections in animal models, but to be effecti...

journal_title：Human vaccines & immunotherapeutics

authors： Zheng Z,Diaz-Arévalo D,Guan H,Zeng M

更新日期：2018-07-03 00:00:00

abstract：:Human papillomavirus (HPV) infection is common in women and also the main cause of cervical cancer. Based on a dynamic compartmental model, we aimed to evaluate the population impact and cost-effectiveness of strategies that combined cervical cancer screening and HPV schoolgirl vaccination for Chinese women. The effec...

journal_title：Human vaccines & immunotherapeutics

authors： Ma X,Harripersaud K,Smith K,Fairley CK,Zou H,Zou Z,Wang Y,Zhuang G,Zhang L

更新日期：2020-12-03 00:00:00

abstract：:Purpose: Gaps remain in the public's knowledge of the human papillomavirus (HPV). We assessed racial/ethnic and gender disparities in knowledge and awareness of HPV and the HPV vaccine among US adults. METHODS:Data from the Health Information National Trends Survey 4 Cycle 3 (September - December 2013) and Cycle 4 (A...

journal_title：Human vaccines & immunotherapeutics

authors： Adjei Boakye E,Tobo BB,Rojek RP,Mohammed KA,Geneus CJ,Osazuwa-Peters N

更新日期：2017-11-02 00:00:00

abstract：:In Japan, government support for human papillomavirus (HPV) vaccination began in November 2010. However, the mass media repeatedly reported on severe adverse events. The Japanese Ministry of Health, Labor and Welfare suspended proactive recommendations for HPV vaccines in June 2013. Japan's HPV vaccination rate droppe...

journal_title：Human vaccines & immunotherapeutics

authors： Tozawa-Ono A,Kamada M,Teramoto K,Hareyama H,Kodama S,Kasai T,Iwanari O,Koizumi T,Ozawa N,Suzuki M,Kinoshita K

更新日期：2020-10-29 00:00:00

abstract：:Psoriasis is a chronic, immune skin disease associated with significant morbidity. Development of psoriasis is influenced by numerous genes, one allele is HLA-CW*0602. Other genes and single nucleotide polymorphisms affect immunologic pathways and antimicrobial peptide synthesis. Dendritic cells initiate psoriasis by ...

journal_title：Human vaccines & immunotherapeutics

authors： Kaffenberger BH,Lee GL,Tyler K,Chan DV,Jarjour W,Ariza ME,Williams MV,Wong HK

更新日期：2014-01-01 00:00:00

abstract：:MENK, a penta-peptide is considered as being involved in the regulatory feedback loop between the immune and neuroendocrine systems, with marked modulation of various functions of human immune cells. The aim of the present work was to investigate change of lymphocyte subpopulations in peripheral blood of 50 cancer pat...

journal_title：Human vaccines & immunotherapeutics

authors： Wang Q,Gao X,Yuan Z,Wang Z,Meng Y,Cao Y,Plotnikoff NP,Griffin N,Shan F

更新日期：2014-01-01 00:00:00

abstract：:Maternal vaccination offers the opportunity to protect pregnant women and their infants against potentially serious disease. As both pregnant women and their newborns are vulnerable to severe illness, the potential public health impact of mass maternal vaccination programs is remarkable. Several high-income countries ...

journal_title：Human vaccines & immunotherapeutics

authors： Regan AK

更新日期：2016-12-01 00:00:00

abstract：:The objective of this study was to calculate Vaccine Effectiveness (VE) in healthcare workers (HCW) and to compare VE between patients and HCW. A case-control investigation based on the prospective study was conducted between 2004 and 2009 in a teaching hospital. All HCW with influenza-like illness (ILI) from particip...

journal_title：Human vaccines & immunotherapeutics

authors： Vanhems P,Baghdadi Y,Roche S,Bénet T,Regis C,Lina B,Robert O,Voirin N,Ecochard R,Amour S

更新日期：2016-01-01 00:00:00

abstract：:The relationship between obesity and vaccine efficacy is a serious issue. Previous studies have shown that vaccine efficacy is lower in the obese than in the non-obese. Here, we examined the influence of obesity on the efficacy of influenza vaccination using high fat diet (HFD) and regular fat diet (RFD) mice that wer...

journal_title：Human vaccines & immunotherapeutics

authors： Park HL,Shim SH,Lee EY,Cho W,Park S,Jeon HJ,Ahn SY,Kim H,Nam JH

更新日期：2014-01-01 00:00:00

abstract：:Background: The expansion of available vaccines in recent years has increased the overall costs of the vaccine program and put pressure on providers responsible for vaccination. In England in 2016-17, GP practices responsible for vaccinating their local population were paid £227 million. However, the costs to general ...

journal_title：Human vaccines & immunotherapeutics

authors： Crocker-Buque T,Mohan K,Ramsay M,Edelstein M,Mounier-Jack S

更新日期：2019-01-01 00:00:00

abstract：:The present study evaluated the safety and immunogenicity of the 2013/2014 trivalent surface antigen inactivated subunit seasonal influenza virus vaccine Fluvirin® in healthy adults (18 - ≤ 60 years) and elderly (>60 years). The vaccine contained 15 µg haemagglutinin protein from each of influenza A/California/7/2009 ...

journal_title：Human vaccines & immunotherapeutics

authors： Roggelin L,Vinnemeier CD,Meyer S,Witte K,Marx L,Theeß W,Burchard GD,Rolling T,Cramer JP

更新日期：2015-01-01 00:00:00

abstract：:The interesting article by Simas et. al. describes an outbreak case with over 600 individuals who exhibited neurological symptoms and which occurred in a town located at the northern region of Colombia in 2014. The community associated this event to the second-dose vaccination campaign against the Human Papillomavirus...

journal_title：Human vaccines & immunotherapeutics

authors： Idrovo AJ,Pinilla-Monsalve GD,Manrique-Hernández EF

更新日期：2019-01-01 00:00:00

abstract：:Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), is a major health problem particularly in developing countries. The available vaccines have certain limitations regarding their efficacy, and inability to induce an immune response especially in individuals under 2 years of age. Conjugate vaccines ...

journal_title：Human vaccines & immunotherapeutics

authors： Ali A,An SJ,Cui C,Haque A,Carbis R

更新日期：2012-02-01 00:00:00

abstract：:Background: Despite long standing recommendations of pneumococcal and influenza vaccination for adults age 65 years and older and wide-spread availability to vaccination services, vaccination coverage in the United states is low. We sought to explore reasons patients reportedly did not receive these vaccines.Methods: ...

journal_title：Human vaccines & immunotherapeutics

authors： Shen AK,Warnock R,Selna W,Chu S,Kelman JA

更新日期：2020-05-03 00:00:00

abstract：BACKGROUND:Adolescents are the primary target population for human papillomavirus (HPV) vaccination. The objective of this study is to explore the acceptability of HPV vaccines and evaluate factors related to willingness to be vaccinated among Chinese adolescents. METHODS:A nation-wide survey was conducted across 14 s...

journal_title：Human vaccines & immunotherapeutics

authors： Zhang X,Wang Z,Ren Z,Li Z,Ma W,Gao X,Zhang R,Qiao Y,Li J

更新日期：2020-10-29 00:00:00

abstract：:The present study is to measure the expression of programmed death (PD)-1 / programmed death ligand-1 (PD-L1) negative costimulatory molecules, soluble format sPD-1 in patients with immune thrombocytopenia (ITP), and to investigate their correlation with the secretion of cytokines. A total of 35 patients with ITP were...

journal_title：Human vaccines & immunotherapeutics

authors： Wang Y,Pang N,Wang X,Liu Y,Wang X,Wang L,Sun M,Yasen H,Zhao F,Fan W,Guo X,Ding J

更新日期：2018-04-03 00:00:00

abstract：:Overexpressed tumor-self antigens represent the largest group of candidate vaccine targets. Those exhibiting a role in oncogenesis may be some of the least studied but perhaps most promising. This review considers this subset of self antigens by highlighting vaccine efforts for some of the better known members and foc...

journal_title：Human vaccines & immunotherapeutics

authors： Bright RK,Bright JD,Byrne JA

更新日期：2014-01-01 00:00:00

abstract：:Varicella zoster virus (VZV) is primarily known for causing varicella in childhood, but can reactivate again as herpes zoster (HZ) after a period of latency, mainly in persons older than 50 years. Universal varicella vaccination was introduced in Germany in 2004, while HZ vaccination has not been recommended yet. We a...

journal_title：Human vaccines & immunotherapeutics

authors： Horn J,Karch A,Damm O,Kretzschmar ME,Siedler A,Ultsch B,Weidemann F,Wichmann O,Hengel H,Greiner W,Mikolajczyk RT

更新日期：2016-07-02 00:00:00

abstract：:Meningococcal serogroup B (MenB) is the predominant cause of invasive meningococcal disease in the United States, with older adolescents and young adults attending college at increased risk. Notably, MenB caused all meningococcal disease outbreaks at US colleges between 2011 and 2018. MenB disease is vaccine-preventab...

journal_title：Human vaccines & immunotherapeutics

authors： McDaniel A,Dempsey A,Srivastava A

更新日期：2019-01-01 00:00:00

abstract：:The main causes of secondary immunodeficiency at a pediatric age include infectious diseases (mainly HIV infection), malignancies, haematopoietic stem cell or solid organ transplantation and autoimmune diseases. Children with secondary immunodeficiency have an increased risk of severe infectious diseases that could be...

journal_title：Human vaccines & immunotherapeutics

authors： Esposito S,Prada E,Lelii M,Castellazzi L

更新日期：2015-01-01 00:00:00