Ebola vaccines in clinical trial: The promising candidates.

abstract：:Italy was one of the first countries in the world to introduce a routine vaccination program against HBV for newborns and 12-y-old children. From a clinical point of view, such strategy was clearly successful. The objective of our study was to verify whether, at 20 y from its implementation, hepatitis B universal vacc...

journal_title：Human vaccines & immunotherapeutics

authors： Boccalini S,Taddei C,Ceccherini V,Bechini A,Levi M,Bartolozzi D,Bonanni P

更新日期：2013-05-01 00:00:00

abstract：:In 2000, China was declared polio-free. However, in 2018, wild poliovirus (WPV) was still endemic in two of its neighboring countries, making WPV importation and outbreak alarming possibilities. This study documents the seroprevalence of poliovirus antibodies before and after the polio vaccine switch in 2012 and 2017 ...

journal_title：Human vaccines & immunotherapeutics

authors： Li J,Zhang Z,Zhang H,Li M,Li X,Lu L,Huang F,Wu J

更新日期：2020-07-23 00:00:00

abstract：:This study aimed to describe the disparities in immunization coverage between National Immunization Program (NIP) vaccines and non-NIP vaccines in Yiwu and to identify potential determinants. A face-to-face interview-based questionnaire survey among 423 migrant children born from 1 June 2010 to 31 May 2013 was conduct...

journal_title：Human vaccines & immunotherapeutics

authors： Hu Y,Luo S,Tang X,Lou L,Chen Y,Guo J

更新日期：2015-01-01 00:00:00

abstract：:The effective protective HIV vaccine should elicit either protective antibodies or effective T cell response, or both. To improve the efficacy of HIV-1 vaccines, HLA polymorphism and HIV-1 diversity are 2 key factors to be considered for vaccine development. In this study, we expressed a recombinant multi-epitope prot...

journal_title：Human vaccines & immunotherapeutics

authors： Yang Y,Zhu Q,Sun W,Guo J,Ning X,Li Q,Guo Y,Li J,Kou Z,Zhou Y

更新日期：2017-06-03 00:00:00

abstract：:Hepatitis A is a vaccine-preventable infection caused by the HA virus (HAV) with transitional to intermediate endemicity in China. An inactivated vaccine first licensed in China in 2010 (Avaxim® 80U Pediatric) is indicated for primary and booster vaccination in children from 12 months to 15 years of age. This Phase IV...

journal_title：Human vaccines & immunotherapeutics

authors： Shi N,Rasuli A,Thollot Y

更新日期：2019-01-01 00:00:00

abstract：:In France, the incidence of invasive meningococcal disease (IMD) is around 1/100,000, with the following trends over the 2011-2018 period: a leading role of group B in subjects <15 years, a decrease of group C among <1 year since 2017, an increase of group W in all age groups including subjects <1 year since 2014 and ...

journal_title：Human vaccines & immunotherapeutics

authors： Taha MK,Gaudelus J,Deghmane AE,Caron F

更新日期：2020-10-02 00:00:00

abstract：BACKGROUND:The prevalence of occult hepatitis B (HB) infection (OBI) in HB-vaccinated diabetic children has not yet been tested. Here, we aimed to determine the prevalence of OBI among HB-vaccinated children and adolescents with insulin-dependent diabetes mellitus (IDDM). RESULTS:Eighty-seven (51.2%) children had a ti...

journal_title：Human vaccines & immunotherapeutics

authors： Elrashidy H,El-Didamony G,Elbahrawy A,Hashim A,Alashker A,Morsy MH,Elwassief A,Elmestikawy A,Abdallah AM,Mohammad AG,Mostafa M,George NM,Abdelhafeez H

更新日期：2014-01-01 00:00:00

abstract：:Combined therapy using chemotherapeutic drugs and immunotherapeutics offers some promise for treating patients with cancer. In this study, we evaluated whether cisplatin delivered by intratumoral (IT)-electroporation (EP) might enhance antitumor activity against established B16 melanoma and whether further addition of...

journal_title：Human vaccines & immunotherapeutics

authors： Kim H,Sin JI

更新日期：2012-11-01 00:00:00

abstract：:Rotavirus (RV) infection is the primary cause for childhood gastroenteritis worldwide. In Korea, RV infection is most common among children less than 5 years of age. This post-licensure study was conducted to further evaluate the RV vaccine (RIX4414) to provide additional local clinical data to the Korean Food and Dru...

journal_title：Human vaccines & immunotherapeutics

authors： Kim JS,Bae CW,Lee KY,Park MS,Choi YY,Kim KN,Kim JD,Park WS,Sin JB,Kim EA,Lee SG,Kim CS,Cha SH,Hong YJ,Shin SM,Shim GH,Choi KM,Yang JW,Liu A,Suryakiran PV,Han HH

更新日期：2012-06-01 00:00:00

abstract：:The practice of passive immunization with human immune globulin (IG) for the control of communicable diseases (measles, rubella and hepatitis A) differs somewhat between Australia, the United States of America, the United Kingdom, and New Zealand despite the many similarities of these countries, including disease inci...

journal_title：Human vaccines & immunotherapeutics

authors： Young MK,Cripps AW

更新日期：2013-09-01 00:00:00

abstract：:The 2014-2016 Ebola virus outbreak in West Africa led to advances in the development of vaccines against Ebola. This study examined factors associated with willingness to pay for an Ebola vaccine among a U.S. national sample during the recent Ebola outbreak. From April 30-May 8, 2015, a national survey was conducted u...

journal_title：Human vaccines & immunotherapeutics

authors： Painter JE,von Fricken ME,Viana de O Mesquita S,DiClemente RJ

更新日期：2018-07-03 00:00:00

abstract：:DC-based therapeutic vaccines as a promising strategy against chronic infections and cancer have been validated in several clinical trials. However, DC-based vaccines are complex and require many in vitro manipulations, which makes this a personalized and expensive therapeutic approach. In contrast, DNA-based vaccines...

journal_title：Human vaccines & immunotherapeutics

authors： Li J,Valentin A,Beach RK,Alicea C,Felber BK,Pavlakis GN

更新日期：2015-01-01 00:00:00

abstract：:Pertussis is one of the most prevalent vaccine-preventable diseases worldwide. The true infection rate is significantly higher than the reported incidence rate. An increased prevalence of pertussis in older populations has been found, mainly caused by waning immunity after vaccination. Vaccine-induced immunity differs...

journal_title：Human vaccines & immunotherapeutics

authors： Chen Z,He Q

更新日期：2017-04-03 00:00:00

abstract：:Individuals infected with human immunodeficiency virus (HIV) have excess risk of developing human papillomavirus (HPV)-related disease. A substantial fraction of HPV-associated cancers is caused by HPV serotypes not included in the currently available vaccines. Among healthy women, both Cervarix(®) (HPV-16/18, GlaxoSm...

journal_title：Human vaccines & immunotherapeutics

authors： Toft L,Tolstrup M,Müller M,Sehr P,Bonde J,Storgaard M,Østergaard L,Søgaard OS

更新日期：2014-01-01 00:00:00

abstract：AIM:Pertussis continues to be a common worldwide infection in pediatric and adult populations. We aimed to study epidemiological and clinical characteristics of infants and children admitted for pertussis to a tertiary-care hospital and to investigate the risk factors for pediatric intensive care unit (PICU) admission....

journal_title：Human vaccines & immunotherapeutics

authors： Di Camillo C,Vittucci AC,Antilici L,Ciarlitto C,Linardos G,Concato C,Lancella L,Villani A

更新日期：2020-08-05 00:00:00

abstract：:Rotavirus immunization strategies have become part of a comprehensive global public health program to control rotavirus-associated gastroenteritis, particularly in infants and children in developing countries. Several studies have reported the efficacy of different rotavirus vaccine dosing schedules, but with mixed fi...

journal_title：Human vaccines & immunotherapeutics

authors： Dai X,Bai R,Jian M,Ji Z,Ding Z,Wang F,Bi Y,Manzamaesso A,Chen T,Luo L,Liu A,Bao F

更新日期：2019-01-01 00:00:00

abstract：:Immune memory after hepatitis B vaccination among adults is still under investigation. In this study, adults who had normal and high antibody response to the primary series of hepatitis B vaccination (HepB) were followed up at 5 years after the primary immunization. A booster dose was given to those who had low hepati...

journal_title：Human vaccines & immunotherapeutics

authors： Wu W,Lv J,Liu J,Yan B,Feng Y,Xu A,Zhang L

更新日期：2018-01-01 00:00:00

abstract：:Malaria has long been recognized as a public health problem. At the community level, vector control, and antimalarial medicines are the main means for reducing incidence, morbidity, and mortality of malaria. A vaccine not only would bring streamlining in the prevention of morbidity and mortality from malaria but also ...

journal_title：Human vaccines & immunotherapeutics

authors： Jindal H,Bhatt B,Malik JS,Sk S,Mehta B

更新日期：2014-01-01 00:00:00

abstract：:Background: Despite long standing recommendations of pneumococcal and influenza vaccination for adults age 65 years and older and wide-spread availability to vaccination services, vaccination coverage in the United states is low. We sought to explore reasons patients reportedly did not receive these vaccines.Methods: ...

journal_title：Human vaccines & immunotherapeutics

authors： Shen AK,Warnock R,Selna W,Chu S,Kelman JA

更新日期：2020-05-03 00:00:00

abstract：:Introduction: International tourism has grown tremendously in the past 2-3 decades in India resulting in exposure of travelers to varied spectrum of diseases prevalent in different parts of the world. Immunization plays a prominent role in protection of the exposed individuals. The objective of the present study was t...

journal_title：Human vaccines & immunotherapeutics

authors： Bhatia V,Palepu S,Parida SP,Singh AK,Sahoo SS

更新日期：2020-09-01 00:00:00

abstract：:Vaccination status is more often evaluated by up-to-date vaccination coverage rather than timeliness of immunization. Delaying vaccination may be dangerous during infancy. The aim of this study was to identify the importance of potentially dangerous vaccination delay (previously defined) and determinants of these dela...

journal_title：Human vaccines & immunotherapeutics

authors： Bailly AC,Gras P,Lienhardt JF,Requillart JC,Vié-le-Sage F,Martinot A,Dubos F

更新日期：2018-04-03 00:00:00

abstract：:Influenza, caused by the influenza virus, is a contagious acute viral respiratory disease with a high incidence rate and wide and rapid spread. Influenza-related morbidity, mortality, and hospitalization rates remain high and are increasing continuously in high-risk groups, with a significant impact on human health an...

journal_title：Human vaccines & immunotherapeutics

authors： Gao D,Yang H,Deng B,Yin G,Song W,Zhang H,Li Y

更新日期：2016-10-02 00:00:00

abstract：:The main objective of this post hoc analysis is to compare the magnitude of the immune response to HPV31/33/45/52 and 58 after a dose of 9vHPV vaccine given to naïve (previously unvaccinated) subjects and subjects previously vaccinated with a dose of 2vHPV or 4vHPV vaccine. Results from two clinical trials conducted i...

journal_title：Human vaccines & immunotherapeutics

authors： Sauvageau C,Panicker G,Unger ER,De Serres G,Schiller J,Ouakki M,Gilca V

更新日期：2020-03-03 00:00:00

abstract：:Some health care providers have adopted the policy of refusing to accept into their practices families who refuse to vaccinate their children according to the standard vaccine schedule. While the frustration that drives these policies is understandable, the practice of refusing to see these families is misguided. Such...

journal_title：Human vaccines & immunotherapeutics

authors： Diekema DS

更新日期：2013-12-01 00:00:00

abstract：:The introduction of a serogroup A meningococcal conjugate vaccine in the African meningitis belt has been a remarkable success. Meningitis due to the serogroup A meningococcus, previously responsible for most epidemics, has fallen by 99% in vaccinated countries. Success must, however, not distract from the continuing ...

journal_title：Human vaccines & immunotherapeutics

authors： Stuart JM

更新日期：2018-05-04 00:00:00

abstract：:The currently available drugs to treat hepatitis B virus (HBV) infection include interferons and nucleos(t)ide analogs, which can only induce disease remission and are inefficient for the functional cure of patients with chronic HBV infection (CHB). Since high titers of circulating hepatitis B surface antigen (HBsAg) ...

journal_title：Human vaccines & immunotherapeutics

authors： Gao Y,Zhang TY,Yuan Q,Xia NS

更新日期：2017-08-03 00:00:00

abstract：:Japanese encephalitis (JE) is a serious public health concern in most of Asia. The disease is caused by JE virus (JEV), a flavivirus transmitted by Culex mosquitoes. Several vaccines have been developed to control JE in endemic areas as well as to protect travelers and military personnel who visit or are commissioned ...

journal_title：Human vaccines & immunotherapeutics

authors： Hegde NR,Gore MM

更新日期：2017-06-03 00:00:00

abstract：OBJECTIVE:Compare immune persistence from one dose of each of 3 different hepatitis A vaccines when given to school-age children: a domestic, live attenuated hepatitis A vaccine (H2 vaccine); a domestic inactivated hepatitis A vaccine (Healive®); and an imported, inactivated hepatitis A vaccine (Havrix®),. METHODS:Sch...

journal_title：Human vaccines & immunotherapeutics

authors： Zhang X,An J,Tu A,Liang X,Cui F,Zheng H,Tang Y,Liu J,Wang X,Zhang N,Li H

更新日期：2016-09-01 00:00:00

abstract：:Cancer immunotherapy has seen a tremendous number of failures and only few recent regulatory successes. This review is a first in a series dedicated to evaluate the status of current global clinical pipeline for cancer vaccines. Apart from specific areas of medical need which can be addressed by cancer vaccines, the a...

journal_title：Human vaccines & immunotherapeutics

authors： Kudrin A,Hanna MG Jr

更新日期：2012-08-01 00:00:00

abstract：:We report the findings of three randomized, double-blind, placebo-controlled Phase I studies undertaken to support licensure of the liquid formulation of the human G1P[8] rotavirus (RV) vaccine (RIX4414; GlaxoSmithKline Biologicals SA) in China. Healthy adults aged 18-45 y (n=48) and children aged 2-6 y (n=50) receive...

journal_title：Human vaccines & immunotherapeutics

authors： Li RC,Li YP,Mo ZJ,Luo D,Huang T,Kong JL,Wang LH,Song NS,Liu A,Zhang H,Liao X,Karkada N,Han HH

更新日期：2013-08-01 00:00:00