Polio vaccination campaign in Pakistan: a step towards eradication or still a challenge in hand?

Abstract:

:Polio is an acute viral disease that is still endemic in Pakistan. The polio vaccination program is facing many challenges that result in an increased number of new cases. The success of polio vaccination has been threatened in different parts of Pakistan. In the past, the immunization program was affected by different factors including insecurity, inducing mass migration and displacement, life threats to polio workers, and restricted access to the vulnerable population. Misconceptions and misunderstanding about the polio vaccine are a major obstacle in polio eradication which need to be erased by organized effects of increasing vaccine awareness.

journal_name

Hum Vaccin Immunother

authors

Ahmad T,Khan M,Musa TH,Hui J

doi

10.1080/21645515.2020.1717152

subject

Has Abstract

pub_date

2020-06-02 00:00:00

pages

1444-1445

issue

6

eissn

2164-5515

issn

2164-554X

journal_volume

16

pub_type

杂志文章
  • The polio endgame.

    abstract::Paralytic poliomyelitis is a disease that became a public health issue at the beginning of the twentieth century and was more or less eliminated in developed countries by the early 1970s. The Global Polio Eradication Initiative of WHO has now eradicated endemic polio from all but three countries although re-introducti...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章,评审

    doi:10.4161/21645515.2014.981115

    authors: Minor P

    更新日期:2014-01-01 00:00:00

  • Role and plasticity of Th1 and Th17 responses in immunity to Staphylococcus aureus.

    abstract::The human commensal Staphylococcus aureus (SA) is a leading cause of skin/soft tissue and surgical-site infections, and bacteremia. Functional antibodies and T-cell-mediated immunity, particularly Th1/Th17 responses, are thought to mediate protection. Vaccine development may be hindered by modulation of vaccine-induce...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/21645515.2019.1613126

    authors: Ferraro A,Buonocore SM,Auquier P,Nicolas I,Wallemacq H,Boutriau D,van der Most RG

    更新日期:2019-01-01 00:00:00

  • Approaching a decade since HPV vaccine licensure: Racial and gender disparities in knowledge and awareness of HPV and HPV vaccine.

    abstract::Purpose: Gaps remain in the public's knowledge of the human papillomavirus (HPV). We assessed racial/ethnic and gender disparities in knowledge and awareness of HPV and the HPV vaccine among US adults. METHODS:Data from the Health Information National Trends Survey 4 Cycle 3 (September - December 2013) and Cycle 4 (A...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2017.1363133

    authors: Adjei Boakye E,Tobo BB,Rojek RP,Mohammed KA,Geneus CJ,Osazuwa-Peters N

    更新日期:2017-11-02 00:00:00

  • Are cases of mumps in vaccinated patients attributable to mismatches in both vaccine T-cell and B-cell epitopes?: An immunoinformatic analysis.

    abstract::Resurgent mumps outbreaks have raised questions about the current efficacy of mumps vaccines. We have applied immunoinformatics techniques based on principal component analysis to evaluate patterns in predicted B-cell linear epitopes, MHC binding affinity and cathepsin cleavage in the hemagglutinin neuraminidase prote...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.4161/hv.27139

    authors: Homan EJ,Bremel RD

    更新日期:2014-01-01 00:00:00

  • Novel Coronavirus disease 2019 (COVID-19): new challenges and new responsibilities in developing countries.

    abstract::Novel coronavirus disease 2019 (COVID-19) is caused by the SARS-CoV-2 virus, which belongs to the genus Coronaviridae with its high mutation rate. From the current perspective, we discuss the current status of COVID-19, new challenges, and potential interventions to control the pandemic in developing counties such as ...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2020.1766939

    authors: Anjum FR,Anam S,Rahman SU

    更新日期:2020-10-02 00:00:00

  • Glycoconjugate vaccine strategies for protection against invasive Salmonella infections.

    abstract::Salmonella enterica serovars Typhi and Paratyphi A and B and certain non-typhoidal Salmonella enterica (NTS) serovars are important causes of invasive Salmonella disease worldwide. NTS serovars Typhimurium and Enteritidis typically cause gastroenteritis in healthy children and adults in industrialized countries but in...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章,评审

    doi:10.4161/hv.19158

    authors: Simon R,Levine MM

    更新日期:2012-04-01 00:00:00

  • Targeted therapies for the treatment of non-small-cell lung cancer: Monoclonal antibodies and biological inhibitors.

    abstract::The usual treatments for patients with non-small-cell lung cancer (NSCLC), such as advanced lung adenocarcinoma, are unspecific and aggressive, and include lung resection, radiotherapy and chemotherapy. Recently, treatment with monoclonal antibodies and biological inhibitors has emerged as an effective alternative, ge...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章,评审

    doi:10.1080/21645515.2016.1249551

    authors: Silva AP,Coelho PV,Anazetti M,Simioni PU

    更新日期:2017-04-03 00:00:00

  • Mycobacterial Hsp65 antigen upregulates the cellular immune response of healthy individuals compared with tuberculosis patients.

    abstract::Previously we showed that 65-kDa Mycobacterium leprae heat shock protein (Hsp65) is a target for the development of a tuberculosis vaccine. Here we evaluated peripheral blood mononuclear cells (PBMC) from healthy individuals or tuberculosis patients stimulated with two forms of Hsp65 antigen, recombinant DNA that enco...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2016.1264547

    authors: Wowk PF,Franco LH,Fonseca DMD,Paula MO,Vianna ÉDSO,Wendling AP,Augusto VM,Elói-Santos SM,Teixeira-Carvalho A,Silva FDC,Vinhas SA,Martins-Filho OA,Palaci M,Silva CL,Bonato VLD

    更新日期:2017-05-04 00:00:00

  • Noninvasive vaccination against infectious diseases.

    abstract::The development of a successful vaccine, which should elicit a combination of humoral and cellular responses to control or prevent infections, is the first step in protecting against infectious diseases. A vaccine may protect against bacterial, fungal, parasitic, or viral infections in animal models, but to be effecti...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章,评审

    doi:10.1080/21645515.2018.1461296

    authors: Zheng Z,Diaz-Arévalo D,Guan H,Zeng M

    更新日期:2018-07-03 00:00:00

  • Dendritic cell targeted vaccines: Recent progresses and challenges.

    abstract::Dendritic cells (DCs) are known to be a set of morphology, structure and function of heterogeneous professional antigen presenting cells (APCs), as well as the strongest functional antigen presenting cells, which can absorb, process and present antigens. As the key regulators of innate and adaptive immune responses, D...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2015.1105415

    authors: Chen P,Liu X,Sun Y,Zhou P,Wang Y,Zhang Y

    更新日期:2016-03-03 00:00:00

  • Suppression of TGF-β and IL-10 receptors on self-differentiated dendritic cells by short-hairpin RNAs enhanced activation of effector T-cells against cholangiocarcinoma cells.

    abstract::Cholangiocarcinoma (CCA) is an aggressive tumor that is associated with high rates of recurrence and mortality. This is due, in part, to the fact that CCA cells and their microenvironment secrete immunosuppressive cytokines, transforming growth factor-β (TGF-β) and interleukin-10 (IL-10), that inhibit dendritic cell (...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2019.1701913

    authors: Thepmalee C,Panya A,Sujjitjoon J,Sawasdee N,Poungvarin N,Junking M,Yenchitsomanus PT

    更新日期:2020-10-02 00:00:00

  • Safety of two doses of an inactivated hepatitis a vaccine given 6 months apart in healthy toddlers, children, and adolescents aged 12 months to 15 years in China: a phase IV study.

    abstract::Hepatitis A is a vaccine-preventable infection caused by the HA virus (HAV) with transitional to intermediate endemicity in China. An inactivated vaccine first licensed in China in 2010 (Avaxim® 80U Pediatric) is indicated for primary and booster vaccination in children from 12 months to 15 years of age. This Phase IV...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2018.1539600

    authors: Shi N,Rasuli A,Thollot Y

    更新日期:2019-01-01 00:00:00

  • BBIQ, a pure TLR7 agonist, is an effective influenza vaccine adjuvant.

    abstract::Better adjuvants are needed for vaccines against seasonal influenza. TLR7 agonists are potent activators of innate immune responses and thereby may be promising adjuvants. Among the imidazoquinoline compounds, 1-benzyl-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine (BBIQ) was reported to be a highly active TLR7 agonist but...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2019.1710409

    authors: Kaushik D,Dhingra S,Patil MT,Piplani S,Khanna V,Honda-Okubo Y,Li L,Fung J,Sakala IG,Salunke DB,Petrovsky N

    更新日期:2020-08-02 00:00:00

  • The role of the thymus in COVID-19 disease severity: implications for antibody treatment and immunization.

    abstract::The thymus is a largely neglected organ but plays a significant role in the regulation of adaptive immune responses. The effect of aging on the thymus and immune senescence is well established, and the resulting inflammaging is found to be implicated in the development of many chronic diseases including atherosclerosi...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2020.1818519

    authors: Kellogg C,Equils O

    更新日期:2020-10-16 00:00:00

  • Maternal and infant outcomes among women vaccinated against pertussis during pregnancy.

    abstract::Tetanus, diphtheria, and acellular pertussis (Tdap) vaccination is recommended for all women during each pregnancy to prevent pertussis in young infants. However, data on the safety of this protective measure are limited and conflicting. To assess maternal and infant outcomes associated with administration of this vac...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2016.1157241

    authors: Berenson AB,Hirth JM,Rahman M,Laz TH,Rupp RE,Sarpong KO

    更新日期:2016-08-02 00:00:00

  • The relationship between meteorological factors and mumps incidence in Guangzhou, China, 2005-2012:.

    abstract:BACKGROUND:Over the past decade, there have been resurgences and large-scale outbreaks of mumps worldwide. Little evidence is available on the relationship between meteorological factors and the incidence of mumps. We aimed to explore the effects of meteorological factors on mumps incidence. METHODS:A Poisson regressi...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.4161/hv.29286

    authors: Yang Q,Yang Z,Ding H,Zhang X,Dong Z,Hu W,Liu X,Wang M,Hu G,Fu C

    更新日期:2014-01-01 00:00:00

  • A new therapeutic potential for cancers: One CAR with 2 different engines!

    abstract::Tumor cells escape from immune recognition by several mechanisms such as down-regulating of MHC class I molecules, losing of tumor antigens, etc. The purpose of cancer immunotherapy is to robust or reconstruct the capacity of the immune system to recognize and kill tumor cells by overwhelming the mechanisms by which t...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 信件

    doi:10.1080/21645515.2017.1314874

    authors: Sheikhi A,Jafarzadeh A

    更新日期:2017-08-03 00:00:00

  • Novel nanoparticle vaccines for Listeriosis.

    abstract::In recent years, nanomedicine has transformed many areas of traditional medicine, and enabled fresh insights into the prevention of previously difficult to treat diseases. An example of the transformative power of nanomedicine is a recent nano-vaccine against listeriosis, a serious bacterial infection affecting not on...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2015.1063756

    authors: Calderon-Gonzalez R,Marradi M,Garcia I,Petrovsky N,Alvarez-Dominguez C

    更新日期:2015-01-01 00:00:00

  • Therapeutic conserved elements (CE) DNA vaccine induces strong T-cell responses against highly conserved viral sequences during simian-human immunodeficiency virus infection.

    abstract::HIV-specific T-cell responses play a key role in controlling HIV infection, and therapeutic vaccines for HIV that aim to improve viral control will likely need to improve on the T-cell responses induced by infection. However, in the setting of chronic infection, an effective therapeutic vaccine must overcome the enorm...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2018.1448328

    authors: Munson P,Liu Y,Bratt D,Fuller JT,Hu X,Pavlakis GN,Felber BK,Mullins JI,Fuller DH

    更新日期:2018-07-03 00:00:00

  • Study of the association of seventeen single nucleotide polymorphisms and their haplotypes in the TNF-α, IL-2, IL-4 and IL-10 genes with the antibody response to inactivated Japanese encephalitis vaccine.

    abstract::To investigate whether the TNF-α, IL-2, IL-4 and IL-10 genes contribute to variations in vaccine-induced immune responses after immunization with the inactivated Japanese encephalitis vaccine (IJEV), a total of 369 individuals who received the IJEV were enrolled. Based on Japanese encephalitis virus (JEV) neutralizati...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2020.1724743

    authors: Yao Y,Xu X,Li Y,Wang X,Yang H,Chen J,Liu S,Deng Y,Zhao Z,Yin Q,Sun M,Shi L

    更新日期:2020-10-02 00:00:00

  • Distribution of 13-Valent pneumococcal conjugate vaccine serotype streptococcus pneumoniae in adults 50 Years and Older presenting with community-acquired pneumonia in Israel.

    abstract:BACKGROUND:Community acquired pneumonia (CAP) is a major cause of morbidity and mortality worldwide, and is a leading cause of hospitalization in previously healthy individuals without predisposing risk factors or comorbidities. In this study we determined PCV13 serotype distribution in adults aged ≥50 years with radio...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2018.1475811

    authors: Regev-Yochay G,Chowers M,Chazan B,Gonzalez E,Gray S,Zhang Z,Pride M

    更新日期:2018-01-01 00:00:00

  • EV71 vaccination impact on the incidence of encephalitis in patients with hand, foot and mouth disease.

    abstract::In order to analyze the effect of EV71 vaccination on the incidence of encephalitis in patients with HFMD, 292 cases were vaccinated, and 2,486 cases were not vaccinated which were collected in 2018 and 2019. It shows that the incidence rate of encephalitis in vaccinated patients was significantly lower than that in n...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2020.1851129

    authors: Li J,Yin X,Lin A,Nie X,Liu L,Liu S,Li N,Wang P,Song S,Wang S,Xu D

    更新日期:2021-01-31 00:00:00

  • Pertussis vaccination in pregnancy.

    abstract::Pertussis has had a resurgence with the highest incidence and complication rates in young infants, and deaths occurring mainly at < age 3 months. Infants are infected by older individuals whose immunity has waned. Strategies such as targeted immunization of infant caregivers have had limited success. Pertussis vaccina...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章,评审

    doi:10.1080/21645515.2016.1171948

    authors: Healy CM

    更新日期:2016-08-02 00:00:00

  • Overview of the cancer vaccine field: are we moving forward?

    abstract::Cancer immunotherapy has seen a tremendous number of failures and only few recent regulatory successes. This review is a first in a series dedicated to evaluate the status of current global clinical pipeline for cancer vaccines. Apart from specific areas of medical need which can be addressed by cancer vaccines, the a...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章,评审

    doi:10.4161/hv.20474

    authors: Kudrin A,Hanna MG Jr

    更新日期:2012-08-01 00:00:00

  • Electroporation driven delivery of both an IL-12 expressing plasmid and cisplatin synergizes to inhibit B16 melanoma tumor growth through an NK cell mediated tumor killing mechanism.

    abstract::Combined therapy using chemotherapeutic drugs and immunotherapeutics offers some promise for treating patients with cancer. In this study, we evaluated whether cisplatin delivered by intratumoral (IT)-electroporation (EP) might enhance antitumor activity against established B16 melanoma and whether further addition of...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.4161/hv.22346

    authors: Kim H,Sin JI

    更新日期:2012-11-01 00:00:00

  • Overcoming barriers to HPV vaccination: A randomized clinical trial of a culturally-tailored, media intervention among African American girls.

    abstract::Although genital HPV is the most prevalent STI in the US, rates of vaccination uptake among high-risk subgroups remain low. Investigations of vaccine compliance have mainly targeted mother-daughter dyads, which in some settings may prove difficult. This study examines an innovative culturally tailored, computer-delive...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/21645515.2015.1070996

    authors: DiClemente RJ,Murray CC,Graham T,Still J

    更新日期:2015-01-01 00:00:00

  • Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaques.

    abstract::HIV sequence diversity and the propensity of eliciting immunodominant responses targeting inessential variable regions are hurdles in the development of an effective AIDS vaccine. We developed a DNA vaccine comprising conserved elements (CE) of SIV p27Gag and HIV-1 Env and found that priming vaccination with CE DNA is...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2018.1489949

    authors: Hu X,Lu Z,Valentin A,Rosati M,Broderick KE,Sardesai NY,Marx PA,Mullins JI,Pavlakis GN,Felber BK

    更新日期:2018-01-01 00:00:00

  • Human papillomavirus prevalence, genomic diversity and related risk factors in HIV-positive women from a countryside city in the state of Rio de Janeiro.

    abstract::Human papillomavirus (HPV) can cause genital warts and HPV-related cancer.People living with human immunodeficiency virus (HIV)are more symptomatic for HPV infections.Campos dos Goytacazes,a municipality of Rio de Janeiro,introduced the quadrivalent HPV vaccine (4vHPV)for HIV-positive women four years before initiatio...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2020.1799666

    authors: Miguel Haddad Kury C,Santos KCDS,Carestiato FN,Rapozo G,Leandro CG,Fernandes LA,Silva PRT,Passos MRL,Cruz OG,Cavalcanti SMB

    更新日期:2020-09-22 00:00:00

  • Site-specific glycosylation profile of influenza A (H1N1) hemagglutinin through tandem mass spectrometry.

    abstract::The study of influenza virus evolution in humans has revealed a significant role of glycosylation profile alterations in the viral glycoproteins - hemagglutinin (HA) and neuraminidase (NA), in the emergence of both seasonal and pandemic strains. Viral antigenic drift can modify the number and location of glycosylation...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2017.1377871

    authors: Cruz E,Cain J,Crossett B,Kayser V

    更新日期:2018-03-04 00:00:00

  • A recombinant multi-epitope protein MEP1 elicits efficient long-term immune responses against HIV-1 infection.

    abstract::The effective protective HIV vaccine should elicit either protective antibodies or effective T cell response, or both. To improve the efficacy of HIV-1 vaccines, HLA polymorphism and HIV-1 diversity are 2 key factors to be considered for vaccine development. In this study, we expressed a recombinant multi-epitope prot...

    journal_title:Human vaccines & immunotherapeutics

    pub_type: 杂志文章

    doi:10.1080/21645515.2017.1281488

    authors: Yang Y,Zhu Q,Sun W,Guo J,Ning X,Li Q,Guo Y,Li J,Kou Z,Zhou Y

    更新日期:2017-06-03 00:00:00