当前位置： SCI文献检索 > Nature Communications期刊下所有文献 > Strain-resolved analysis of hospital rooms and infants reveals overlap between the human and room microbiome.

Strain-resolved analysis of hospital rooms and infants reveals overlap between the human and room microbiome.

Abstract：

:Preterm infants exhibit different microbiome colonization patterns relative to full-term infants, and it is speculated that the hospital room environment may contribute to infant microbiome development. Here, we present a genome-resolved metagenomic study of microbial genotypes from the gastrointestinal tracts of infants and from the neonatal intensive care unit (NICU) room environment. Some strains detected in hospitalized infants also occur in sinks and on surfaces, and belong to species such as Staphylococcus epidermidis, Enterococcus faecalis, Pseudomonas aeruginosa, and Klebsiella pneumoniae, which are frequently implicated in nosocomial infection and preterm infant gut colonization. Of the 15 K. pneumoniae strains detected in the study, four were detected in both infant gut and room samples. Time series experiments showed that nearly all strains associated with infant gut colonization can be detected in the room after, and often before, detection in the gut. Thus, we conclude that a component of premature infant gut colonization is the cycle of microbial exchange between the room and the occupant.

journal_name

Nat Commun

journal_title

Nature communications

authors

Brooks B,Olm MR,Firek BA,Baker R,Thomas BC,Morowitz MJ,Banfield JF

doi

10.1038/s41467-017-02018-w

subject

Has Abstract

pub_date

2017-11-27 00:00:00

pages

1814

issue

1

issn

2041-1723

pii

10.1038/s41467-017-02018-w

journal_volume

8

pub_type

杂志文章

相关文献

Nature Communications文献大全
  • Coexistence of distinct skyrmion phases observed in hybrid ferromagnetic/ferrimagnetic multilayers.

    abstract：:Materials hosting magnetic skyrmions at room temperature could enable compact and energetically-efficient storage such as racetrack memories, where information is coded by the presence/absence of skyrmions forming a moving chain through the device. The skyrmion Hall effect leading to their annihilation at the racetrac...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-020-20025-2

    authors： Mandru AO,Yıldırım O,Tomasello R,Heistracher P,Penedo M,Giordano A,Suess D,Finocchio G,Hug HJ

    更新日期：2020-12-11 00:00:00

  • Universal far-from-equilibrium dynamics of a holographic superconductor.

    abstract：:Symmetry-breaking phase transitions are an example of non-equilibrium processes that require real-time treatment, a major challenge in strongly coupled systems without long-lived quasiparticles. Holographic duality provides such an approach by mapping strongly coupled field theories in D dimensions into weakly coupled...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms8406

    authors： Sonner J,Del Campo A,Zurek WH

    更新日期：2015-06-23 00:00:00

  • Size and surface charge characterization of nanoparticles with a salt gradient.

    abstract：:Exosomes are nanometer-sized lipid vesicles present in liquid biopsies and used as biomarkers for several diseases including cancer, Alzheimer's, and central nervous system diseases. Purification and subsequent size and surface characterization are essential to exosome-based diagnostics. Sample purification is, howeve...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-020-15889-3

    authors： Rasmussen MK,Pedersen JN,Marie R

    更新日期：2020-05-11 00:00:00

  • Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naive pluripotency.

    abstract：:Clusters of enhancers, referred as to super-enhancers (SEs), control the expression of cell identity genes. The organisation of these clusters, and how they are remodelled upon developmental transitions remain poorly understood. Here, we report the existence of two types of enhancer units within SEs typified by distin...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-020-14916-7

    authors： Bell E,Curry EW,Megchelenbrink W,Jouneau L,Brochard V,Tomaz RA,Mau KHT,Atlasi Y,de Souza RA,Marks H,Stunnenberg HG,Jouneau A,Azuara V

    更新日期：2020-02-28 00:00:00

  • eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription.

    abstract：:Insulin regulates glycaemia, lipogenesis and increases mRNA translation. Cells with reduced eukaryotic initiation factor 6 (eIF6) do not increase translation in response to insulin. The role of insulin-regulated translation is unknown. Here we show that reduction of insulin-regulated translation in mice heterozygous f...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms9261

    authors： Brina D,Miluzio A,Ricciardi S,Clarke K,Davidsen PK,Viero G,Tebaldi T,Offenhäuser N,Rozman J,Rathkolb B,Neschen S,Klingenspor M,Wolf E,Gailus-Durner V,Fuchs H,Hrabe de Angelis M,Quattrone A,Falciani F,Biffo S

    更新日期：2015-09-18 00:00:00

  • Semiconducting single-walled carbon nanotubes sorting with a removable solubilizer based on dynamic supramolecular coordination chemistry.

    abstract：:Highly pure semiconducting single-walled carbon nanotubes (SWNTs) are essential for the next generation of electronic devices, such as field-effect transistors and photovoltaic applications; however, contamination by metallic SWNTs reduces the efficiency of their associated devices. Here we report a simple and efficie...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms6041

    authors： Toshimitsu F,Nakashima N

    更新日期：2014-10-03 00:00:00

  • Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation.

    abstract：:The shift from maternal to embryonic control is a critical developmental milestone in preimplantation development. Widespread transcriptomic and epigenetic remodeling facilitate this transition from terminally differentiated gametes to totipotent blastomeres, but the identity of transcription factors (TF) and genomic ...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-020-18508-3

    authors： Halstead MM,Ma X,Zhou C,Schultz RM,Ross PJ

    更新日期：2020-09-17 00:00:00

  • Assembly of complex viruses exemplified by a halophilic euryarchaeal virus.

    abstract：:Many of the largest known viruses belong to the PRD1-adeno structural lineage characterised by conserved pseudo-hexameric capsomers composed of three copies of a single major capsid protein (MCP). Here, by high-resolution cryo-EM analysis, we show that a class of archaeal viruses possess hetero-hexameric MCPs which mi...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-019-09451-z

    authors： De Colibus L,Roine E,Walter TS,Ilca SL,Wang X,Wang N,Roseman AM,Bamford D,Huiskonen JT,Stuart DI

    更新日期：2019-03-29 00:00:00

  • Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism.

    abstract：:Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regulate lipid biosynthesis and adipogenesis by controlling the expression of several enzymes required for cholesterol, fatty acid, triacylglycerol and phospholipid synthesis. In vertebrates, SREBP activation is mainly contr...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-019-09152-7

    authors： Bertolio R,Napoletano F,Mano M,Maurer-Stroh S,Fantuz M,Zannini A,Bicciato S,Sorrentino G,Del Sal G

    更新日期：2019-03-22 00:00:00

  • A CD36 ectodomain mediates insect pheromone detection via a putative tunnelling mechanism.

    abstract：:CD36 transmembrane proteins have diverse roles in lipid uptake, cell adhesion and pathogen sensing. Despite numerous in vitro studies, how they act in native cellular contexts is poorly understood. A Drosophila CD36 homologue, sensory neuron membrane protein 1 (SNMP1), was previously shown to facilitate detection of l...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms11866

    authors： Gomez-Diaz C,Bargeton B,Abuin L,Bukar N,Reina JH,Bartoi T,Graf M,Ong H,Ulbrich MH,Masson JF,Benton R

    更新日期：2016-06-15 00:00:00

  • Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology.

    abstract：:Modular and orthogonal genetic logic gates are essential for building robust biologically based digital devices to customize cell signalling in synthetic biology. Here we constructed an orthogonal AND gate in Escherichia coli using a novel hetero-regulation module from Pseudomonas syringae. The device comprises two co...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms1516

    authors： Wang B,Kitney RI,Joly N,Buck M

    更新日期：2011-10-18 00:00:00

  • Reconstructing neuronal circuitry from parallel spike trains.

    abstract：:State-of-the-art techniques allow researchers to record large numbers of spike trains in parallel for many hours. With enough such data, we should be able to infer the connectivity among neurons. Here we develop a method for reconstructing neuronal circuitry by applying a generalized linear model (GLM) to spike cross-...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-019-12225-2

    authors： Kobayashi R,Kurita S,Kurth A,Kitano K,Mizuseki K,Diesmann M,Richmond BJ,Shinomoto S

    更新日期：2019-10-02 00:00:00

  • A pairwise maximum entropy model accurately describes resting-state human brain networks.

    abstract：:The resting-state human brain networks underlie fundamental cognitive functions and consist of complex interactions among brain regions. However, the level of complexity of the resting-state networks has not been quantified, which has prevented comprehensive descriptions of the brain activity as an integrative system....

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms2388

    authors： Watanabe T,Hirose S,Wada H,Imai Y,Machida T,Shirouzu I,Konishi S,Miyashita Y,Masuda N

    更新日期：2013-01-01 00:00:00

  • Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration.

    abstract：:Choroidal neovascularization (CNV) is a major cause of visual impairment in patients suffering from wet age-related macular degeneration (AMD), particularly when refractory to intraocular anti-VEGF injections. Here we report that treatment with the oral mineralocorticoid receptor (MR) antagonist spironolactone reduces...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-018-08125-6

    authors： Zhao M,Mantel I,Gelize E,Li X,Xie X,Arboleda A,Seminel M,Levy-Boukris R,Dernigoghossian M,Prunotto A,Andrieu-Soler C,Rivolta C,Canonica J,Naud MC,Lechner S,Farman N,Bravo-Osuna I,Herrero-Vanrell R,Jaisser F,Behar-Co

    更新日期：2019-01-21 00:00:00

  • Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.

    abstract：:The heterogeneity of neurodegenerative diseases is a key confound to disease understanding and treatment development, as study cohorts typically include multiple phenotypes on distinct disease trajectories. Here we introduce a machine-learning technique-Subtype and Stage Inference (SuStaIn)-able to uncover data-driven...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-018-05892-0

    authors： Young AL,Marinescu RV,Oxtoby NP,Bocchetta M,Yong K,Firth NC,Cash DM,Thomas DL,Dick KM,Cardoso J,van Swieten J,Borroni B,Galimberti D,Masellis M,Tartaglia MC,Rowe JB,Graff C,Tagliavini F,Frisoni GB,Laforce R Jr,Fin

    更新日期：2018-10-15 00:00:00

  • Engineering skyrmions in transition-metal multilayers for spintronics.

    abstract：:Magnetic skyrmions are localized, topologically protected spin structures that have been proposed for storing or processing information due to their intriguing dynamical and transport properties. Important in terms of applications is the recent discovery of interface stabilized skyrmions as evidenced in ultra-thin tra...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms11779

    authors： Dupé B,Bihlmayer G,Böttcher M,Blügel S,Heinze S

    更新日期：2016-06-03 00:00:00

  • Stagnant forearc mantle wedge inferred from mapping of shear-wave anisotropy using S-net seafloor seismometers.

    abstract：:Shear-wave anisotropy in Earth's mantle helps constrain the lattice-preferred orientation of anisotropic minerals due to viscous flow. Previous studies at the Japan Trench subduction zone using land-based seismic networks identified strong anisotropy in the mantle wedge, reflecting viscous flow induced by the subducti...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-020-19541-y

    authors： Uchida N,Nakajima J,Wang K,Takagi R,Yoshida K,Nakayama T,Hino R,Okada T,Asano Y

    更新日期：2020-11-10 00:00:00

  • Molecular basis for PrimPol recruitment to replication forks by RPA.

    abstract：:DNA damage and secondary structures can stall the replication machinery. Cells possess numerous tolerance mechanisms to complete genome duplication in the presence of such impediments. In addition to translesion synthesis (TLS) polymerases, most eukaryotic cells contain a multifunctional replicative enzyme called prim...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms15222

    authors： Guilliam TA,Brissett NC,Ehlinger A,Keen BA,Kolesar P,Taylor EM,Bailey LJ,Lindsay HD,Chazin WJ,Doherty AJ

    更新日期：2017-05-23 00:00:00

  • Mechanisms of drug interactions between translation-inhibiting antibiotics.

    abstract：:Antibiotics that interfere with translation, when combined, interact in diverse and difficult-to-predict ways. Here, we explain these interactions by "translation bottlenecks": points in the translation cycle where antibiotics block ribosomal progression. To elucidate the underlying mechanisms of drug interactions bet...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-020-17734-z

    authors： Kavčič B,Tkačik G,Bollenbach T

    更新日期：2020-08-11 00:00:00

  • The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma.

    abstract：:FAM46C is one of the most frequently mutated genes in multiple myeloma. Here, using a combination of in vitro and in vivo approaches, we demonstrate that FAM46C encodes an active non-canonical poly(A) polymerase which enhances mRNA stability and gene expression. Reintroduction of active FAM46C into multiple myeloma ce...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-017-00578-5

    authors： Mroczek S,Chlebowska J,Kuliński TM,Gewartowska O,Gruchota J,Cysewski D,Liudkovska V,Borsuk E,Nowis D,Dziembowski A

    更新日期：2017-09-20 00:00:00

  • A supervised learning framework for chromatin loop detection in genome-wide contact maps.

    abstract：:Accurately predicting chromatin loops from genome-wide interaction matrices such as Hi-C data is critical to deepening our understanding of proper gene regulation. Current approaches are mainly focused on searching for statistically enriched dots on a genome-wide map. However, given the availability of orthogonal data...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-020-17239-9

    authors： Salameh TJ,Wang X,Song F,Zhang B,Wright SM,Khunsriraksakul C,Ruan Y,Yue F

    更新日期：2020-07-09 00:00:00

  • Highly robust crystalsome via directed polymer crystallization at curved liquid/liquid interface.

    abstract：:Lipids and amphiphilic block copolymers spontaneously self-assemble in water to form a plethora of micelles and vesicles. They are typically fluidic in nature and often mechanically weak for applications such as drug delivery and gene therapeutics. Mechanical properties of polymeric materials could be improved by form...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms10599

    authors： Wang W,Qi H,Zhou T,Mei S,Han L,Higuchi T,Jinnai H,Li CY

    更新日期：2016-02-03 00:00:00

  • Quantifying climate sensitivity and climate-driven change in North American amphibian communities.

    abstract：:Changing climate will impact species' ranges only when environmental variability directly impacts the demography of local populations. However, measurement of demographic responses to climate change has largely been limited to single species and locations. Here we show that amphibian communities are responsive to clim...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-018-06157-6

    authors： Miller DAW,Grant EHC,Muths E,Amburgey SM,Adams MJ,Joseph MB,Waddle JH,Johnson PTJ,Ryan ME,Schmidt BR,Calhoun DL,Davis CL,Fisher RN,Green DM,Hossack BR,Rittenhouse TAG,Walls SC,Bailey LL,Cruickshank SS,Fellers GM,G

    更新日期：2018-09-25 00:00:00

  • Physical descriptor for the Gibbs energy of inorganic crystalline solids and temperature-dependent materials chemistry.

    abstract：:The Gibbs energy, G, determines the equilibrium conditions of chemical reactions and materials stability. Despite this fundamental and ubiquitous role, G has been tabulated for only a small fraction of known inorganic compounds, impeding a comprehensive perspective on the effects of temperature and composition on mate...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-018-06682-4

    authors： Bartel CJ,Millican SL,Deml AM,Rumptz JR,Tumas W,Weimer AW,Lany S,Stevanović V,Musgrave CB,Holder AM

    更新日期：2018-10-09 00:00:00

  • A role for actin flexibility in thin filament-mediated contractile regulation and myopathy.

    abstract：:Striated muscle contraction is regulated by the translocation of troponin-tropomyosin strands over the thin filament surface. Relaxation relies partly on highly-favorable, conformation-dependent electrostatic contacts between actin and tropomyosin, which position tropomyosin such that it impedes actomyosin association...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-020-15922-5

    authors： Viswanathan MC,Schmidt W,Franz P,Rynkiewicz MJ,Newhard CS,Madan A,Lehman W,Swank DM,Preller M,Cammarato A

    更新日期：2020-05-15 00:00:00

  • Liquid phase blending of metal-organic frameworks.

    abstract：:The liquid and glass states of metal-organic frameworks (MOFs) have recently become of interest due to the potential for liquid-phase separations and ion transport, alongside the fundamental nature of the latter as a new, fourth category of melt-quenched glass. Here we show that the MOF liquid state can be blended wit...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-018-04553-6

    authors： Longley L,Collins SM,Zhou C,Smales GJ,Norman SE,Brownbill NJ,Ashling CW,Chater PA,Tovey R,Schönlieb CB,Headen TF,Terrill NJ,Yue Y,Smith AJ,Blanc F,Keen DA,Midgley PA,Bennett TD

    更新日期：2018-06-15 00:00:00

  • Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3.

    abstract：:How developmental programs reactivate in regeneration is a fundamental question in biology. We addressed this question through the study of Wound Induced Hair follicle Neogenesis (WIHN), an adult organogenesis model where stem cells regenerate de novo hair follicles following deep wounding. The exact mechanism is unce...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/s41467-019-10811-y

    authors： Kim D,Chen R,Sheu M,Kim N,Kim S,Islam N,Wier EM,Wang G,Li A,Park A,Son W,Evans B,Yu V,Prizmic VP,Oh E,Wang Z,Yu J,Huang W,Archer NK,Hu Z,Clemetson N,Nelson AM,Chien A,Okoye GA,Miller LS,Ghiaur G,Kang S

    更新日期：2019-06-26 00:00:00

  • Three-dimensional protonic conductivity in porous organic cage solids.

    abstract：:Proton conduction is a fundamental process in biology and in devices such as proton exchange membrane fuel cells. To maximize proton conduction, three-dimensional conduction pathways are preferred over one-dimensional pathways, which prevent conduction in two dimensions. Many crystalline porous solids to date show one...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms12750

    authors： Liu M,Chen L,Lewis S,Chong SY,Little MA,Hasell T,Aldous IM,Brown CM,Smith MW,Morrison CA,Hardwick LJ,Cooper AI

    更新日期：2016-09-13 00:00:00

  • Synapsin II desynchronizes neurotransmitter release at inhibitory synapses by interacting with presynaptic calcium channels.

    abstract：:In the central nervous system, most synapses show a fast mode of neurotransmitter release known as synchronous release followed by a phase of asynchronous release, which extends over tens of milliseconds to seconds. Synapsin II (SYN2) is a member of the multigene synapsin family (SYN1/2/3) of synaptic vesicle phosphop...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms2515

    authors： Medrihan L,Cesca F,Raimondi A,Lignani G,Baldelli P,Benfenati F

    更新日期：2013-01-01 00:00:00

  • Export of a single drug molecule in two transport cycles by a multidrug efflux pump.

    abstract：:Secondary multidrug transporters use ion concentration gradients to energize the removal from cells of various antibiotics. The Escherichia coli multidrug transporter MdfA exchanges a single proton with a single monovalent cationic drug molecule. This stoichiometry renders the efflux of divalent cationic drugs energet...

    journal_title：Nature communications

    pub_type： 杂志文章

    doi：10.1038/ncomms5615

    authors： Fluman N,Adler J,Rotenberg SA,Brown MH,Bibi E

    更新日期：2014-08-08 00:00:00