Abstract：
:The role of the macromolecular constituents of human oviductal fluid (hOF) in reproductive physiology is poorly understood. Oviductal fluid contains proteins derived by transudation from serum and those synthesized and secreted by the tubal mucosa. In this communication, we describe purification of hOF-specific proteins. As a first step, serum proteins were removed with an immunoaffinity gel. Fractionation of the proteins unique to hOF was accomplished with DEAE-cellulose chromatography. One of these proteins was obtained in a highly purified state after gel filtration on G-75 Sephadex. This protein of 54 kDa molecular weight had a pI of 4.5 and contained carbohydrate. We propose that this hOF glycoprotein be designated "human oviductin I" (hOV I).
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Wagh PV,Lippes Jdoi
10.1016/s0015-0282(16)60433-8subject
Has Abstractpub_date
1989-01-01 00:00:00pages
81-8issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(16)60433-8journal_volume
51pub_type
杂志文章abstract：OBJECTIVE:To investigate the expression profiles of microRNA (miRNA) in human testes showing different histopathological patterns. DESIGN:Microarray with quantitative real-time polymerase chain reaction (qRT-PCR) validation. SETTING:University research and clinical institutes. PATIENT(S):Azoospermic men who underwen...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.09.009
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To explore the value of serum vascular endothelial growth factor (VEGF) concentrations during IVF cycles in predicting the risk of ovarian hyperstimulation syndrome (OHSS). DESIGN:Prospective study. SETTING:London Women's Clinic. PATIENT(S):One hundred seven women undergoing IVF. Mild OHSS developed in 10 ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00447-6
更新日期：1999-02-01 00:00:00
abstract：OBJECTIVE:To study the messenger ribonucleic acid (mRNA) expression of receptors for insulin, insulin-like growth factor I (IGF-I), and insulin-like growth factor II (IGF-II) in human fetal ovaries and uteri at 10, 15, 19, and 22 weeks' gestation. Insulin, IGF-I, and IGF-II are postulated to have paracrine and autocrin...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55924-x
更新日期：1993-05-01 00:00:00
abstract：:Mild-stimulation protocols with in vitro fertilization (IVF) generally aim to use less medication than conventional IVF. This guideline evaluates pregnancy and live-birth rates in patients expected to be poor responders using mild ovarian stimulation and natural-cycle protocols vs conventional IVF. ...
journal_title：Fertility and sterility
pub_type： 杂志文章,实务指引
doi：10.1016/j.fertnstert.2018.03.019
更新日期：2018-06-01 00:00:00
abstract：:Fertilization, embryo development, and successful pregnancy can be achieved after transfer of embryos derived from brown oocytes at the same rate as embryos from morphologically normal oocytes. Therefore, brown oocytes are probably normal and this morphological criterion does not seem to be indicative of any adverse o...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.03.056
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVE:To evaluate whether ethnicity is associated with involuntary childlessness and perceived reasons for difficulties in becoming pregnant. DESIGN:Cross-sectional analysis of baseline data from a longitudinal cohort. SETTING:Multiethnic, community-based observational study of US women. PATIENT(S):Women in midl...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2011.08.039
更新日期：2011-11-01 00:00:00
abstract：:Transvaginal follicular aspiration (TVA) with ultrasonically guided needles allows the transfer of in vitro generated embryos to the fallopian tubes (TET), performing only one surgical procedure in the process. Up to now, this approach has been used to treat 16 couples with infertility due to severe male factor. Folli...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60136-x
更新日期：1988-09-01 00:00:00
abstract：OBJECTIVE:To determine whether NR5A1 (SF-1) variants are a cause of primary ovarian insufficiency (POI) in 26 young women with similar genetic background. DESIGN:Genetic and functional mutation study. SETTING:University hospitals. PATIENT(S):Genetic analysis of the NR5A1 gene in 26 XX girls with POI. INTERVENTION(S...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.10.026
更新日期：2013-02-01 00:00:00
abstract：:One hundred and two women with insulin-resistant polycystic ovary syndrome were randomized to treatment with a vitamin B preparation, metformin, or both, in conjunction with standard infertility treatment. Plasma homocysteine levels were significantly reduced by both B vitamins and metformin, but to a greater degree b...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2006.11.071
更新日期：2007-07-01 00:00:00
abstract：:One hundred and twenty rats were divided into six groups and laparotomized. In three of the groups the cecum was left intact. In one of these groups the cecum was only lifted up through the abdominal incision and then replaced in the abdominal cavity. In another group the intact cecum was bathed with a certain amount ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43584-3
更新日期：1978-10-01 00:00:00
abstract：OBJECTIVE:To describe two cases of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) with testicular sperm in men with immotile cilia syndromes. DESIGN:Case report. SETTING:A university-based male infertility clinic and assisted reproduction unit. PATIENT(S):Two couples with male factor infert...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)01974-4
更新日期：2001-09-01 00:00:00
abstract：OBJECTIVE:To determine whether it is possible to identify and diagnose accurately Müllerian anomalies with three-dimensional (3-D) ultrasound (US). DESIGN:Controlled blinded clinical study. SETTING:Normal human volunteers undergoing infertility evaluation in a university hospital. PATIENTS:Forty-two patients who und...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)58147-3
更新日期：1996-03-01 00:00:00
abstract：:This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Authors. The entire group of investigators contributing to this study requests to withdraw this article. We ...
journal_title：Fertility and sterility
pub_type： 杂志文章,撤回出版物
doi：10.1016/j.fertnstert.2020.09.001
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVE:To evaluate vaginal bleeding profiles with lower doses of conjugated equine estrogens (CEE) and medroxyprogesterone acetate (MPA) as continuous combined therapy. DESIGN:The Women's Health, Osteoporosis, Progestin, Estrogen (Women's HOPE) study, a randomized, double-blind, placebo-controlled trial. SETTING:S...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0015-0282(01)01792-7
更新日期：2001-06-01 00:00:00
abstract：OBJECTIVE:To investigate the diagnostic relevance of serum cytokine concentrations in ectopic pregnancy (EP). DESIGN:Cohort study. SETTING:University hospital. PATIENT(S):Seventeen women with EP, 22 women with miscarriage, and 33 women with normal intrauterine pregnancy, at comparable stages of gestation. INTERVENT...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)04853-7
更新日期：2003-04-01 00:00:00
abstract：OBJECTIVE:To develop and validate a specific simple measure of insulin sensitivity using oral glucose tolerance test (OGTT) values for lean polycystic ovary syndrome (PCOS) women. DESIGN:Retrospective study. SETTING:Gynecologic Outpatient Clinic of University Hospital, affiliated with Unit of Gynecologic Endocrinolog...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.04.004
更新日期：2014-07-01 00:00:00
abstract：:The PF environment is one that hosts the processes of ovulation, gamete transportation, fertilization, and early embryonic development. The cellular and acellular constituents of this dynamic fluid are in a constant interactive state, being influenced by the physiologic events of the menstrual cycle and pelvic disease...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/s0015-0282(16)59280-2
更新日期：1987-07-01 00:00:00
abstract：OBJECTIVE:To investigate the potential effects of TAT-PRDX2 protein supplementation to the cryopreservation medium on post-thaw sperm quality and function. DESIGN:In vitro prospective study. SETTING:Medical university hospital. PATIENT(S):Fifty normozoospermic, 50 asthenozoospermic, and 50 oligoasthenozoospermic men...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2018.07.008
更新日期：2018-11-01 00:00:00
abstract：:Plasma concentrations of luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), testosterone (T), and 17 beta-estradiol (E2) have been measured in men complaining of infertility in comparison with men of proven fertility. Subgrouping of patients was achieved on the basis of the presence or abse...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)46582-9
更新日期：1982-10-01 00:00:00
abstract：OBJECTIVE:To study the effects of hormone therapy on brain activation patterns during verbal memory in postmenopausal women. DESIGN:A randomized, double-blind placebo-controlled cross-over study was performed. SETTING:A tertiary care university medical center. PATIENT(S):Ten healthy postmenopausal women (age range 5...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2008.04.040
更新日期：2009-07-01 00:00:00
abstract：:Endometriosis has been associated with corpus luteum inadequacy and abnormalities of luteal phase progesterone (P) secretion. In this study, abnormal luteolysis, as a second factor of luteal dysfunction, was assessed in 13 women with endometriosis and 25 control patients by measurement of ovarian vein estradiol (E2) a...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)59224-3
更新日期：1987-06-01 00:00:00
abstract：:Pain associated with endometriosis may involve many mechanisms and requires careful evaluation to confirm the diagnosis and exclude other potential causes. Both medical and surgical treatments for pain related to endometriosis are effective, and choice of treatment must be individualized. This document replaces the do...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.02.012
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVE:To assess right-left differences in ultrasonographic markers of ovarian morphology and determine the impact on the diagnosis of polycystic ovarian morphology (PCOM). DESIGN:A cross-sectional study of data collected from 2006 to 2018. SETTING:Academic clinical research centers. PATIENT(S):Women with polycys...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2019.06.016
更新日期：2019-11-01 00:00:00
abstract：:Forty-four women were prospectively evaluated with a 3-hour oral glucose tolerance test while they used a new weekly oral contraceptive drug, R2323. The blood tests were carried out before the drug was administered and again 3 months after its use. Both blood glucose and plasma insulin levels were measured. In the 40 ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43513-2
更新日期：1978-09-01 00:00:00
abstract：OBJECTIVE:To evaluate concentration of granulocyte colony-stimulating factor (G-CSF) in serum and follicular fluid (FF) at the time of oocyte retrieval and to detect expression of G-CSF and its receptor by luteinized granulosa cells (GCs). DESIGN:Collection of serum and FF at the time of oocyte retrieval. SETTING:A u...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.09.039
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVE:To determine whether estrogen down-regulates MCP-1 in vascular endothelial cells. DESIGN:A prospective comparative study. SETTING:Academic research environment. PATIENT(S):Human umbilical vein endothelial cells (n = 3) and human coronary artery endothelial cells (n = 3) obtained from females. INTERVENTION...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)03223-x
更新日期：2002-03-01 00:00:00
abstract：:Midluteal phase corpora lutea (CL) obtained from women induced with 50 mg (n = 5), 100 mg (n = 5), and 150 mg (n = 5) of clomiphene citrate (CC) were measured for luteinizing hormone/human chorionic gonadotropin (LH/hCG) concentrations and cytosol progesterone (P) and 17 alpha-hydroxyprogesterone (17-OHP) and compared...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：:Multiple factors influence the outcome of in vitro fertilization and embryo transfer (IVF-ET). This prospective study was designed to assess their relative importance, in order to improve prognostic ability and treatment success. Prior to IVF-ET, couples were divided into "good" (GP) and "poor" (PP) prognosis groups a...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60676-3
更新日期：1989-05-01 00:00:00
abstract：OBJECTIVE:To investigate the optimal protocol for cryopreservation of human embryos obtained from IVF. DESIGN:Prospective randomized study. SETTING:Consenting patients in an academic research environment. PATIENTS:Couples undergoing IVF. INTERVENTIONS:A cohort of 2,220 supernumerary multicellular embryos were obtai...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVE:To investigate the association between several factors such as demographics, personal habits, reproductive factors, menstrual characteristics, contraception, and clinical profile and the probability of having endometriosis. SETTING:Ten clinical institutions in the Montreal area. PATIENT(S):A total of 2777 s...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.10.038
更新日期：2004-06-01 00:00:00
