Birth after intracytoplasmic sperm injection with use of testicular sperm from men with Kartagener/immotile cilia syndrome.

Abstract:

OBJECTIVE:To describe two cases of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) with testicular sperm in men with immotile cilia syndromes. DESIGN:Case report. SETTING:A university-based male infertility clinic and assisted reproduction unit. PATIENT(S):Two couples with male factor infertility due to Kartagener/immotile cilia syndrome. INTERVENTION(S):IVF/ICSI with testicular sperm. MAIN OUTCOME MEASURE(S):Semen characteristics, sperm viability, fertilization rate, and pregnancy. RESULT(S):With testicular sperm, the two pronuclear fertilization rates were 63% and 60% in two cases. One case resulted in the birth of normal healthy girl. CONCLUSION(S):With testicular sperm, successful oocyte fertilization after ICSI in couples with male Kartagener/immotile cilia syndrome is possible despite the lack of sperm motility.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Cayan S,Conaghan J,Schriock ED,Ryan IP,Black LD,Turek PJ

doi

10.1016/s0015-0282(01)01974-4

keywords:

subject

Has Abstract

pub_date

2001-09-01 00:00:00

pages

612-4

issue

3

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(01)01974-4

journal_volume

76

pub_type

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