Eosinophilic biomarkers for detection of acute exacerbation of chronic obstructive pulmonary disease with or without pulmonary embolism.

abstract：:The aim of this study was to evaluate the clinical value of multidetector-row computed tomography (MDCT) and magnetic resonance imaging (MRI) in the diagnosis and treatment of complex fractures of the tibial plateau. A total of 71 patients with complex fractures of the tibial plateau (estimated Schatzker classificatio...

journal_title：Experimental and therapeutic medicine

authors： Xu Y,Li Q,Su P,Shen T,Zhu Y

更新日期：2014-01-01 00:00:00

abstract：:Peptide P7 specifically binds with basic fibroblast growth factor (bFGF) to inhibit the proliferation and invasion of numerous types of cancer cell. However, this effect has remained to be demonstrated in ovarian cancer-derived cell lines. In the present study, the protein P7 was used treat bFGF-stimulated SKOV3 epith...

journal_title：Experimental and therapeutic medicine

authors： Chen Q,Yang Z,Chen X,Shu L,Qu W

更新日期：2019-04-01 00:00:00

abstract：:The present study aimed to investigate the expression of complement component 1, q subcomponent-binding protein (C1QBP) in colon cancer cells, and identify proteins that interact with C1QBP. Total proteins were extracted from both the tumor and normal tissues of 22 patients with colon cancer and analyzed using liquid ...

journal_title：Experimental and therapeutic medicine

authors： Kim K,Kim MJ,Kim KH,Ahn SA,Kim JH,Cho JY,Yeo SG

更新日期：2017-05-01 00:00:00

abstract：:The present study aimed to investigate the effects of levodopa (LEV) on cellular apoptosis in a rabbit model of steroid-associated necrosis of the femoral head (SANFH). A total of 44 healthy adult Chinese rabbits were randomly divided into three groups: Group A (n=15), administered a combination of lipopolysaccharide ...

journal_title：Experimental and therapeutic medicine

authors： Xi H,Tao W,Jian Z,Sun X,Gong X,Huang L,Dong T

更新日期：2017-01-01 00:00:00

abstract：:The aim of the present study was to examine the effect of CCAAT enhancer binding protein β (C/EBPβ) on human breast cancer cells. The plasmids pCDH-C/EBPβ and pLKO.1-shC/EBPβ were constructed and were infected into MDA-MB-468 cells, to provide C/EBPβ overexpressing and C/EBPβ knockdown cells, respectively. Cell viabil...

journal_title：Experimental and therapeutic medicine

authors： Cao J,Wang M,Wang T

更新日期：2017-08-01 00:00:00

abstract：:The host response to spinal cord injury (SCI) can lead to an ischemic environment that can induce cell death. Therapeutic interventions using neurotrophic factors have focused on the prevention of such reactions in order to reduce this cell death. Vascular endothelial growth factor (VEGF) is a potent angiogenic and va...

journal_title：Experimental and therapeutic medicine

authors： Yu H,Lin B,He Y,Zhang W,Xu Y

更新日期：2015-05-01 00:00:00

abstract：:Shikonin (SK), a naturally occurring naphthoquinone, exhibits antitumor activity. However, its precise mechanisms of action are unknown. In the present study, the effects of SK on NCI-H460 human lung cancer cells were investigated. It was found that SK reduced cell viability and induced apoptosis in the NCI-H460 cells...

journal_title：Experimental and therapeutic medicine

authors： Qu D,Chen YU,Xu XM,Zhang M,Zhang YI,Li SQ

更新日期：2015-04-01 00:00:00

abstract：:Single-port laparoscopic technology is effective in minimally invasive surgery. However, this technology requires expensive instrumentation. In the present study, an alternative minimally invasive technique, periumbilical laparoscopic surgery through triple channels using common instrumentation, is introduced. Increas...

journal_title：Experimental and therapeutic medicine

authors： Ge JY,Wang L,Zou H,Zhang XW

更新日期：2013-04-01 00:00:00

abstract：:Electrospinning using biocompatible polymer scaffolds, seeded with or without stem cells, is considered a promising technique for producing fibrous scaffolds with therapeutic possibilities for ischemic heart disease. However, no optimal scaffolds for treating ischemic heart disease have been identified thus far. In th...

journal_title：Experimental and therapeutic medicine

authors： Du M,Gu J,Wang J,Xue Y,Ma Y,Mo X,Xue S

更新日期：2019-05-01 00:00:00

abstract：:Esthesioneuroblastoma (ENB), also known as olfactory neuroblastoma, is a rare malignant tumor that accounts for 3% of all tumors of the nasal cavity. The incidence of ENB is 0.4 cases per million in the general population, and the most common symptoms are nasal obstruction and epistaxis. Previous studies have indicate...

journal_title：Experimental and therapeutic medicine

authors： Sabongi JG,Gonçalves MC,Alves CD,Alves J,Scapulatempo-Neto C,Moriguchi SM

更新日期：2016-11-01 00:00:00

abstract：:Renal ischemia reperfusion (IR) is a major cause of acute kidney injury with no effective treatment. Chrysin is an anti-inflammatory, anti-oxidant and anti-cancer agent. However, the effect of chrysin on renal IR injury remains unknown. In this study, sham operation, IR and IR+chrysin group mice were treated with or w...

journal_title：Experimental and therapeutic medicine

authors： Xu M,Shi H,Liu D

更新日期：2019-03-01 00:00:00

abstract：:Tanshinone IIA (TSIIA) is a major component of Salvia miltiorrhiza, a Chinese herb that exhibits a therapeutic effect on polycystic ovary syndrome (PCOS). The present study replicated PCOS via the neonatal treatment of estradiol in mice. Estrous cycles, body and ovarian weight, serum levels of testosterone and estradi...

journal_title：Experimental and therapeutic medicine

authors： Jin J,Hu QY,Xu WW,Zhu WJ,Liu B,Liu J,Wang W,Zhou HF

更新日期：2019-05-01 00:00:00

abstract：:The aim of the present study was to establish a stem cell line for multi-mode imaging (in vivo fluorescence imaging, magnetic resonance imaging and 99mTc single-photon emission computed tomography) and to study the biological activity, stemness, proliferative activity and differentiation ability of superparamagnetic i...

journal_title：Experimental and therapeutic medicine

authors： Meng Y,Liu H,Bian N,Gong J,Zhong X,Huang C,Liang W,Xu H

更新日期：2018-09-01 00:00:00

abstract：:Due to the wide introduction of screening tests, patients with neoplastic diseases of the uterine cervix trend to be diagnosed in early stages of the disease, and less invasive surgical procedures are needed in certain cases. In this respect, the technique of sentinel lymph node dissection has been widely implemented ...

journal_title：Experimental and therapeutic medicine

authors： Bacalbasa N,Balescu I,Diaconu C,Savu C,Savu C,Neacsu A,Belu E,Bratu O,Cretoiu D,Halmaciu I,Iliescu L,Balalau C,Filipescu A,Vilcu M,Brezean I

更新日期：2020-10-01 00:00:00

abstract：:Erythropoietin (EPO), a glycoprotein originally known for its important role in the stimulation of erythropoiesis, has recently been shown to have significant protective effects in animal models of kidney and intestinal ischemia-reperfusion injury (IRI). However, the mechanism underlying these protective effects remai...

journal_title：Experimental and therapeutic medicine

authors： Rong R,Xijun X

更新日期：2015-08-01 00:00:00

abstract：:The aim of the present study was to determine whether the myocardial protective function of Shenmai injection (SM) during ischemia/reperfusion (I/R) is attributable to its regulation of intracellular calcium (Ca2+) and phospholamban (PLB) levels. Cultured neonatal Sprague Dawley rat cardiomyocytes were used to compare...

journal_title：Experimental and therapeutic medicine

authors： Ye LF,Zheng YR,Wang LH

更新日期：2015-10-01 00:00:00

abstract：:Discoid lateral meniscus of the knee causes a high morbidity in China. Since the traditional treatment to open the capsule and resect the meniscus often results in arthritis, it is now believed that a discoid lateral meniscus should be treated with arthroscopy to preserve part of the meniscus. The current study aimed ...

journal_title：Experimental and therapeutic medicine

authors： Cao H,Zhang Y,Qian W,Cheng XH,Ke Y,Guo XP

更新日期：2012-11-01 00:00:00

abstract：:Hyperlipidemia is a risk factor of kidney damage that can lead to chronic kidney disease. Studies have shown that exercise reduces kidney damage; however, the specific mechanisms underlying the protective effects of exercise remain unclear. For 12 weeks, 8-week-old male apolipoprotein E-deficient (ApoE-/-) mice were r...

journal_title：Experimental and therapeutic medicine

authors： Qian C,Yang Q,Guo L,Zhu H,You X,Liu H,Sun Y

更新日期：2021-02-01 00:00:00

abstract：:MicroRNA (miR)-202 has been reported to be involved in the regulation of human cancer progression including bladder cancer, non-small cell lung cancer, pancreatic cancer and esophageal squamous cell carcinoma. However, the function of miR-202 in prostate cancer remains largely unknown. The present study demonstrated t...

journal_title：Experimental and therapeutic medicine

authors： Zhang S,Cai J,Xie W,Luo H,Yang F

更新日期：2018-08-01 00:00:00

abstract：:Assisted reproductive technology (ART) including in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) have been shown to be associated with abnormal genomic imprinting, thus increasing the incidence of imprinting disorders such as Beckwith-Wiedemann syndrome (BWS) and Angelman syndrome (AS) in ART-...

journal_title：Experimental and therapeutic medicine

authors： Zheng HY,Shi XY,Wang LL,Wu YQ,Chen SL,Zhang L

更新日期：2011-07-01 00:00:00

abstract：:Previous studies have demonstrated that aripiprazole (APZ), a third-generation atypical antipsychotic drug, exhibits anti-depressant and neuroprotective effects by promoting dopaminergic neuronal cell recovery in stroke. To investigate the neuroprotective effects of APZ, behavioral and histopathological experiments we...

journal_title：Experimental and therapeutic medicine

authors： Gil CH,Kim YR,Lee HJ,Jung DH,Shin HK,Choi BT

更新日期：2018-01-01 00:00:00

abstract：:The aim of the present study was to investigate the effect of Forkhead family transcription factor P3 (Foxp3) knockdown on the function of cluster of differentiation (CD)4+CD25+ regulatory T cell (Tregs) and the tumor growth of a hepatocellular carcinoma (HCC) mouse model. CD4+CD25+ Tregs and CD4+CD25- T cells were so...

journal_title：Experimental and therapeutic medicine

authors： Shi C,Zhang Y,Yang H,Dong T,Chen Y,Xu Y,Yang X,Liu P

更新日期：2018-01-01 00:00:00

abstract：:The present study aimed to evaluate the safety and efficiency of ciliary sulcus implantation of intraocular lens (IOL) in patients that had undergone manual small incision cataract surgery (MSICS) complicated by large posterior capsule rupture (LPCR). A total of 11 eyes taken from 11 patients in Brazzaville, Republic ...

journal_title：Experimental and therapeutic medicine

authors： Zhao J,Yu J,Wang T,Mban B

更新日期：2019-02-01 00:00:00

abstract：:Phosphocitrate (PC) and its analogue, PC-β ethyl ester, inhibit articular cartilage degeneration in Hartley guinea pigs. However, the underlying molecular mechanisms remain unclear. The present study aimed to investigate the hypothesis that PC exerted its disease-modifying effect on osteoarthritis (OA), in part, by in...

journal_title：Experimental and therapeutic medicine

authors： Sun Y,Kiraly AJ,Cox M,Mauerhan DR,Hanley EN Jr

更新日期：2018-04-01 00:00:00

abstract：:This study aimed to assess the effect on solid tumors of mild temperature hyperthermia (MTH) combined with hexamethylenetetramine (HMTA) or tirapazamine (TPZ). Squamous cell carcinoma (SCC VII) tumor-bearing mice were continuously administered 5-bromo-2'-deoxyuridine (BrdU) to label intratumor proliferating (P) cells....

journal_title：Experimental and therapeutic medicine

authors： Masunaga SI,Tano K,Nakamura J,Watanabe M,Kashino G,Suzuki M,Kinashi Y,Ono K

更新日期：2010-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) has become a significant public health risk. Long non-coding RNAs (lncRNAs) have been identified as important factors involved in the proliferation, apoptosis and inflammatory cytokine expression of lung cells. Peripheral blood samples from 66 subjects (18 non-smokers, 24 s...

journal_title：Experimental and therapeutic medicine

authors： Lei Z,Guo H,Zou S,Jiang J,Kui Y,Song J

更新日期：2021-01-01 00:00:00

abstract：:Effects of propofol, midazolam and dexmedetomidine on patients with sepsis in intensive care unit (ICU) and on arterial blood gas (ABG) were studied. In total 429 ICU patients with sepsis, admitted to Renji Hospital, School of Medicine, Shanghai Jiaotong University from May 2015 to January 2019, were selected as resea...

journal_title：Experimental and therapeutic medicine

authors： Ding J,Chen Y,Gao Y

更新日期：2019-12-01 00:00:00

abstract：:The aim of the present study was to investigate the expression levels of estrogen receptor (ER) α and β and human epidermal growth factor receptor-2 (Her-2), as well as the distribution of breast cancer molecular subtypes in Uygur and Han breast cancer patients. Cancer tissues were collected and analyzed from 709 brea...

journal_title：Experimental and therapeutic medicine

authors： Guo L,Hou X,Dilimina Y,Wang B

更新日期：2014-05-01 00:00:00

abstract：:Bacterial infection is a key factor in airway inflammation. The present study describes the time-dependent changes in the leukocyte counts and cytokine levels of the bronchoalveolar lavage fluid (BALF) following subacute airway inflammation induced by lipopolysaccharide (LPS), a major component of the outer membranes ...

journal_title：Experimental and therapeutic medicine

authors： Liu L,Chen L,Wang Y,Yang H,Chen Y,Xu X,Zhou H,Jiang F,Li T,Wang J

更新日期：2012-12-01 00:00:00

abstract：:Late spontaneous recanalization (SR) of an occluded internal carotid artery (ICA) has been rarely reported and the prognosis of affected patients remains elusive. In the present study, the incidence of late SR of atherosclerotic occlusion of the ICA and associated outcomes were assessed in a single center. A total of ...

journal_title：Experimental and therapeutic medicine

authors： Wu H,Liu Y,Li B,Zhang H,Liu C

更新日期：2018-11-01 00:00:00