Levodopa attenuates cellular apoptosis in steroid-associated necrosis of the femoral head.

abstract：:The aim of this study was to analyze the concentration changes of nuclear factor-κB (NF-κB) and the related inflammatory factors of pre-treatment and post-treatment in children with viral encephalitis, to examine the mechanism of NF-κB in the pathogenesis of child viral encephalitis. Twenty-two children with severe vi...

journal_title：Experimental and therapeutic medicine

authors： Zhang D,Zheng N,Liu X

更新日期：2017-06-01 00:00:00

abstract：:The present study aimed to evaluate the safety and efficiency of ciliary sulcus implantation of intraocular lens (IOL) in patients that had undergone manual small incision cataract surgery (MSICS) complicated by large posterior capsule rupture (LPCR). A total of 11 eyes taken from 11 patients in Brazzaville, Republic ...

journal_title：Experimental and therapeutic medicine

authors： Zhao J,Yu J,Wang T,Mban B

更新日期：2019-02-01 00:00:00

abstract：:In order to evaluate the efficacy and tolerability of oxycodone in moderate-severe cancer-related pain, we conducted a systematic review of randomized controlled trials (RCTs). Publications addressing the efficacy and tolerability of oxycodone in moderate-severe cancer-related pain were selected from the Cochrane libr...

journal_title：Experimental and therapeutic medicine

authors： Wang YM,Liu ZW,Liu JL,Zhang L

更新日期：2012-08-01 00:00:00

abstract：:Nuclear receptor related-1 protein (Nurr1) is a novel orphan member of the nuclear receptor superfamily (the NR4A family) involved in tumorigenesis. The aim of the present study was to investigate the expression and possible function of Nurr1 in pancreatic ductal adenocarcinoma (PDAC). The expression pattern of Nurr1 ...

journal_title：Experimental and therapeutic medicine

authors： Ji L,Gong C,Ge L,Song L,Chen F,Jin C,Zhu H,Zhou G

更新日期：2017-02-01 00:00:00

abstract：:In the present study, the thenar muscles were evaluated using magnetic resonance imaging (MRI), in addition, the correlations between thenar muscle changes, clinical findings and electrodiagnostic results from patients with carpal tunnel syndrome were investigated. The subjects were 13 patients (17 wrists) who were cl...

journal_title：Experimental and therapeutic medicine

authors： Dilokhuttakarn T,Naito K,Kinoshita M,Sugiyama Y,Goto K,Iwase Y,Kaneko K

更新日期：2017-09-01 00:00:00

abstract：:The study was conducted to evaluate the relationship between the blood lactic acid (BLA) level, serum procalcitonin (PCT), C-reactive protein (CRP) and the severity and prognosis of neonatal sepsis. A retrospective analysis was conducted on 90 children with sepsis admitted into the Intensive Care Unit (ICU) of the Hub...

journal_title：Experimental and therapeutic medicine

authors： Jia Y,Wang Y,Yu X

更新日期：2017-09-01 00:00:00

abstract：:The classical analgesic pathway of opioids by binding their receptors in the nervous system is well known. However, little is known regarding opioid analgesia through the anti-inflammatory pathway. The present study aimed to investigate the analgesic and anti-inflammatory effect of β-endorphin on inflammatory pain. A ...

journal_title：Experimental and therapeutic medicine

authors： He X,Huang L,Qiu S,Yin X,Shen Y,Wu Y,Jiang Y,Fang J

更新日期：2018-04-01 00:00:00

abstract：:The initiation and progression of various types of tumors, such as lung neoplasms, are driven by a population of cells with stem cell properties and their microenvironment. Bone marrow mesenchymal stem cells (BM-MSCs) in long-term in vitro culture may exhibit spontaneous changes in stem cell biological properties, inc...

journal_title：Experimental and therapeutic medicine

authors： Zhang YM,Zhang ZM,Guan QL,Liu YQ,Wu ZW,Li JT,Su Y,Yan CL,Luo YL,Qin J,Wang Q,Xie XD

更新日期：2017-10-01 00:00:00

abstract：:The aim of the present study was to summarize the clinical characteristics of nocardiosis caused by Nocardia otitidiscaviarum in order to improve the knowledge of nocardiosis. A case of dissemination nocardiosis caused by N. otitidiscaviarum in an immunocompetent host is reported and the associated literature reviewed...

journal_title：Experimental and therapeutic medicine

authors： Jiang Y,Huang A,Fang Q

更新日期：2016-11-01 00:00:00

abstract：:The status of the three retinoic acid receptors (RARs) α, β and γ in human colorectal cancer (CRC) has not as yet been examined. RARs are in part responsible for the actions of the retinoids (vitamin A and its derivatives), which are essential for human health and survival due to their extensive involvement in numerou...

journal_title：Experimental and therapeutic medicine

authors： Perraud A,Nouaille M,Akil H,Petit D,Labrousse F,Jauberteau MO,Mathonnet M

更新日期：2011-05-01 00:00:00

abstract：:The present study aimed to explore the effects of dexmedetomidine combined with etomidate on the expression levels of interleukin (IL)-17A and S-100β in rats with postoperative cognitive dysfunction (POCD). A total of 50 SD rats were randomly allocated into the control group, model group, etomidate group (Eto group), ...

journal_title：Experimental and therapeutic medicine

authors： Yu X,Xie Y

更新日期：2020-12-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/etm.2017.4943.]. ...

journal_title：Experimental and therapeutic medicine

authors： Li S,Xu G,Gao F,Bi J,Huo R

更新日期：2018-10-01 00:00:00

abstract：:Mitochondrial factor and cell cytokines play important roles in the incidence of vascular dementia (VD), but their correlations with inflammatory and mitochondrial factors and the role of both in the kidney essence deficiency pattern and phlegm turbidity blocking orifice pattern are not clear. This study was aimed at ...

journal_title：Experimental and therapeutic medicine

authors： Sun L

更新日期：2018-01-01 00:00:00

abstract：:Undaria pinnatifida (U. pinnatifida) polysaccharides (UPPS) are considered to be the major bioactive components of U. pinnatifida. The aim of the present study was to investigate the separation, sulfated modification, characterization and monosaccharide composition of UPPS. The optimal processing conditions were as fo...

journal_title：Experimental and therapeutic medicine

authors： Wang FL,Ji YB,Yang B

更新日期：2020-07-01 00:00:00

abstract：:Systemic therapy in patients with concurrent psoriasis and chronic hepatitis B is a challenging task for both dermatologists and gastroenterologists since there is a high risk for hepatitis B virus (HBV) reactivation and hepatic toxicity under biological therapy. The therapeutic management of a patient with psoriasis ...

journal_title：Experimental and therapeutic medicine

authors： Raducan A,Bucur S,Caruntu C,Constantin T,Nita IE,Manolache N,Constantin MM

更新日期：2019-08-01 00:00:00

abstract：:This study aimed to investigate the reliability of ultrasound two-dimensional speckle tracking imaging (2D-STI) for the evaluation of myocardial ischemia in familial hypercholesterolemia (FH) patients. We recruited 28 patients clinically diagnosed with homozygous familial hypercholesterolemia (HoFH) and subjected them...

journal_title：Experimental and therapeutic medicine

authors： Song Y,Zhang RF,Liu Y

更新日期：2017-08-01 00:00:00

abstract：:Nitrogen mustards are chemical agents that are similar to sulfur mustards, with similar toxicities. The present study describes a case of nitrogen mustard-induced acute respiratory failure and myelosuppression in a 33-year-old man. The patient, who was accidentally exposed to nitrogen mustard hydrochloride in a pharma...

journal_title：Experimental and therapeutic medicine

authors： Zhang X,Zhang Z,Chen S,Zhao D,Zhang F,Hu Z,Xiao F,Ma X

更新日期：2015-10-01 00:00:00

abstract：:Bacterial infection is a key factor in airway inflammation. The present study describes the time-dependent changes in the leukocyte counts and cytokine levels of the bronchoalveolar lavage fluid (BALF) following subacute airway inflammation induced by lipopolysaccharide (LPS), a major component of the outer membranes ...

journal_title：Experimental and therapeutic medicine

authors： Liu L,Chen L,Wang Y,Yang H,Chen Y,Xu X,Zhou H,Jiang F,Li T,Wang J

更新日期：2012-12-01 00:00:00

abstract：:Collecting duct carcinoma (CDC), which is also known as Bellini duct carcinoma, accounts for less than 1% of all renal cell carcinoma, which has a poor prognosis. Predominantly, clinicians recognize this disease due to past experience and case reports, and a standard treatment is yet to be established. The present cas...

journal_title：Experimental and therapeutic medicine

authors： Zhu L,Wang Z,Pan C,Peng R,Wei X,Zhong Z

更新日期：2016-08-01 00:00:00

abstract：:Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is an acute event characterized by the worsening of a patient's respiratory symptoms. To the best of our knowledge, few studies have investigated the computed tomography (CT) manifestation of AECOPD. Thus, the aim of the present study was to examine ...

journal_title：Experimental and therapeutic medicine

authors： Cheng T,Wan H,Cheng Q,Guo YI,Qian Y,Fan L,Feng Y,Song Y,Zhou M,Li Q,Shi G,Huang S

更新日期：2016-02-01 00:00:00

abstract：:Synovitis, acne, palmoplantar pustulosis, hyperostosis and osteitis syndrome (SAPHO) is a rare syndrome that affects the skin, bones and joints. Diagnosis of SAPHO syndrome is established on clinical appearance and imaging features. The present case report described the imaging features of three cases of SAPHO with st...

journal_title：Experimental and therapeutic medicine

authors： Duan N,Chen X,Liu Y,Wang J,Wang Z

更新日期：2016-10-01 00:00:00

abstract：:In Traditional Chinese Medicine, Polygonum multiflorum (PM) is known for its anti-aging properties. A previous study by our group showed that extracts of PM were able to prevent and treat bone loss in vivo, and the active components emodin and 2,3,5,4,-tetrahydroxystilbene-2-O-β-glucoside (TSG) promoted the osteogenic...

journal_title：Experimental and therapeutic medicine

authors： Zhou M,Li J,Wu J,Yang Y,Zeng X,Lv X,Cui L,Yao W,Liu Y

更新日期：2017-09-01 00:00:00

abstract：:Tumor-infiltrating lymphocytes (TILs) are produced by resecting tumor tissue and growing and expanding ex vivo large quantities of autologous T cells. Once the TILs are ready for infusion, the patient undergoes a non-myeloablative lympho-depleting course of chemotherapy and subsequent TIL infusion with high-dose bolus...

journal_title：Experimental and therapeutic medicine

authors： Zippel DB,Besser M,Shapira R,Ben-Nun A,Goitein D,Davidson T,Treves AJ,Markel G,Schachter J,Papa MZ

更新日期：2012-05-01 00:00:00

abstract：:The aim of the present study was to evaluate the protein expression level of human epidermal growth factor receptor 2 (HER-2) using immunohistochemistry (IHC), and assess the association with clinicopathological parameters and the prognosis of patients with colorectal cancer (CRC). In addition, the current study obser...

journal_title：Experimental and therapeutic medicine

authors： Tu J,Yu Y,Liu W,Chen S

更新日期：2015-01-01 00:00:00

abstract：:Mutations in keratin 5 (KRT5) or KRT14 genes are responsible for the most severe form of epidermolysis bullosa simplex (EBS), which is EBS generalized severe (EBS-gen sev). To date, only four pathogenic mutations (p.Arg165Ser and p.Lys199Asn in KRT5; p.Arg125Cys and p.Arg125His in KRT14) have been reported to be respo...

journal_title：Experimental and therapeutic medicine

authors： Zhang J,Yan M,Liang J,Li M,Yao Z

更新日期：2016-11-01 00:00:00

abstract：:Tumor hypoxia contributes to the development of resistance to chemotherapeutic drugs in several human cancer cell lines. Atovaquone, an anti-malaria drug approved by the US Food and Drug Administration, has recently demonstrated anti-cancer effects in vitro and in vivo in several cancer models. To assess the potential...

journal_title：Experimental and therapeutic medicine

authors： Fu C,Xiao X,Xu H,Lu W,Wang Y

更新日期：2020-12-01 00:00:00

abstract：:Postmenopausal osteoporosis is a degenerative disease caused by lack of estrogen whereby bone degeneration exceeds bone formation, resulting in loss of bone mass. Various drugs have been utilized in an attempt to ameliorate bone strength in such patients. The aim of the present study was to compare the effects of vita...

journal_title：Experimental and therapeutic medicine

authors： Huang Y

更新日期：2018-01-01 00:00:00

abstract：:In recent years accumulating evidence has indicated that tocotrienol exhibits an oxidation resistance function, decreased cholesterol function, inhibits cancer function and has unique physiological functions, including anti-inflammatory, anti-apoptotic and anti-oxidative properties. The present study investigated the ...

journal_title：Experimental and therapeutic medicine

authors： Xun C,Mamat M,Guo H,Mamati P,Sheng J,Zhang J,Xu T,Liang W,Cao R,Sheng W

更新日期：2017-07-01 00:00:00

abstract：:The present study described the characteristics of three cases of Creutzfeldt-Jakob disease (CJD) in China and analyzed their clinical presentations. The clinical information of the three cases was collected and analyzed. Blood and cerebrospinal fluid (CSF) specimens of the patients were collected for detection of the...

journal_title：Experimental and therapeutic medicine

authors： Wang X,Li N,Liu A,Ma L,Shan P,Jiang W,Zhang Q

更新日期：2017-09-01 00:00:00

abstract：:Single-port laparoscopic technology is effective in minimally invasive surgery. However, this technology requires expensive instrumentation. In the present study, an alternative minimally invasive technique, periumbilical laparoscopic surgery through triple channels using common instrumentation, is introduced. Increas...

journal_title：Experimental and therapeutic medicine

authors： Ge JY,Wang L,Zou H,Zhang XW

更新日期：2013-04-01 00:00:00