Prognosis of patients with late spontaneous recanalization of the atherosclerotic occlusion of internal carotid arteries: A pilot case series.

abstract：:Suppurative hidradenitis and pyoderma gangrenosum are rare disorders that can be seen isolated or even more rare, as part of different autoinflammatory syndromes: Pyoderma gangrenosum, acne, and hidradenitis suppurativa (PASH), pyoderma gangrenosum, acne, pyogenic arthritis, and hidradenitis suppurativa (PAPASH) or ps...

journal_title：Experimental and therapeutic medicine

authors： Turcu G,Ioana Nedelcu R,Teodora Nedelcu I,Hodorogea A,Balaban M,Brinzea A,Nichita L,Gabriela Popp C,Andrada Zurac S,Theodor Andrei R

更新日期：2020-07-01 00:00:00

abstract：:Transvaginal ultrasound (TVUS) is a standard imaging modality for differentiating patients with benign or malignant suspected adnexal mass. To date, numerous studies have assessed the diagnostic accuracy of TVUS in various settings but with variable results. Therefore, the purpose of the present study was to perform a...

journal_title：Experimental and therapeutic medicine

authors： Zhang X,Meng X,Dou T,Sun H

更新日期：2020-12-01 00:00:00

abstract：:The prognostic and predictive value of pre-treatment serum levels of carcinoembryonic antigen (CEA) and cytokeratin-19 fragments (CYFRA 21-1) were assessed in advanced non-small cell lung cancer (NSCLC) patients treated with gefitinib or erlotinib. Pre-treatment CEA and CYFRA 21-1 levels were measured in 123 advanced ...

journal_title：Experimental and therapeutic medicine

authors： Jung M,Kim SH,Lee YJ,Hong S,Kang YA,Kim SK,Chang J,Rha SY,Kim JH,Kim DJ,Cho BC

更新日期：2011-07-01 00:00:00

abstract：:In recent years accumulating evidence has indicated that tocotrienol exhibits an oxidation resistance function, decreased cholesterol function, inhibits cancer function and has unique physiological functions, including anti-inflammatory, anti-apoptotic and anti-oxidative properties. The present study investigated the ...

journal_title：Experimental and therapeutic medicine

authors： Xun C,Mamat M,Guo H,Mamati P,Sheng J,Zhang J,Xu T,Liang W,Cao R,Sheng W

更新日期：2017-07-01 00:00:00

abstract：:The aim of the present study was to investigate the effects of S-adenosyl methionine (SAMe) on infectious premature inflammatory factors and uterine contraction, and to further explore its mechanism of action via the transient receptor protein 3 (TRPC3)/protein kinase Cβ (PKCβ)/C-kinase-activated protein phosphatase-1...

journal_title：Experimental and therapeutic medicine

authors： Ge J,Han T,Li X,Shan L,Zhang J,Hong Y,Xia Y,Wang J,Hou M

更新日期：2018-07-01 00:00:00

abstract：:The activation of monocytes and macrophages is associated with steroid-resistant (SR) asthma. Interleukin-35 (IL-35) is an important anti-inflammatory cytokine, but its regulatory effects on monocytes in patients with SR asthma is not fully understood. Based on clinical response to oral prednisolone, 34 patients with ...

journal_title：Experimental and therapeutic medicine

authors： Qian L,Xu D,Xue F,Li M,Wang X,Liu G

更新日期：2020-05-01 00:00:00

abstract：:At present, the majority of patients with breast cancer are diagnosed at early stages of disease development. However, a considerable number of such cases develop secondary malignancies after a relatively short period of time. The presence of circulating tumor cells (CTCs) has been proposed as a strong biomarker to pr...

journal_title：Experimental and therapeutic medicine

authors： Serrano MJ,Rovira PS,Martínez-Zubiaurre I,Rodriguez MD,Fernández M,Lorente JA

更新日期：2012-07-01 00:00:00

abstract：:Non-adherence to psoriasis treatment has an important impact in controlling chronic disease evolution and the occurrence of systemic comorbidities. Biologic therapy represents a revolutionary treatment, many of the undesirable psychological and socio-economical consequences of conventional topical or systemic therapie...

journal_title：Experimental and therapeutic medicine

authors： Mocanu M,Toader MP,Rezus E,Taranu T

更新日期：2019-12-01 00:00:00

abstract：:The aim of the present study was to examine the effect of CCAAT enhancer binding protein β (C/EBPβ) on human breast cancer cells. The plasmids pCDH-C/EBPβ and pLKO.1-shC/EBPβ were constructed and were infected into MDA-MB-468 cells, to provide C/EBPβ overexpressing and C/EBPβ knockdown cells, respectively. Cell viabil...

journal_title：Experimental and therapeutic medicine

authors： Cao J,Wang M,Wang T

更新日期：2017-08-01 00:00:00

abstract：:The aim of the study was to investigate the effect of stromal cell-derived factor-1 (SDF-1) on myocardial apoptosis and cardiac function recovery in rats with acute myocardial infarction (AMI) and the mechanism of the Toll-like receptor (TLR)-4/nuclear factor-κB (NF-κB) signaling pathway. A total of 64 healthy male F3...

journal_title：Experimental and therapeutic medicine

authors： Liu Y,Gao S,Wang Z,Yang Y,Huo H,Tian X

更新日期：2016-11-01 00:00:00

abstract：:Endometriosis is a common reproductive disorder in women, with a global prevalence of 10-15%. Long noncoding RNAs (lncRNAs) are critical to gene transcription, cell cycle modulation and immune response. The lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) reportedly mediates autophagy of endometr...

journal_title：Experimental and therapeutic medicine

authors： Liu X,Zhang P,Li Y,Zhao N,Han H

更新日期：2021-01-01 00:00:00

abstract：:The hyper-IgM syndromes (HIGMs) are a group of primary immune deficiency diseases characterized by a normal or elevated serum level of IgM and low or absent serum levels of IgG, IgA and IgE. Here, we report a case of X-linked HIGM with a new CD40L gene mutation presenting with eosinophilia. The patient experienced rec...

journal_title：Experimental and therapeutic medicine

authors： Guo LI,Chen BO,Xu B,Lu M,Ning B,Chen Z

更新日期：2015-04-01 00:00:00

abstract：:Several molecules have been proven to be associated with responsiveness to chemotherapy. A clinical study on the expression of excision repair cross-complementing (ERCC)-1 and class III β-tubulin was conducted in advanced stage non-small cell lung cancer (NSCLC) patients. We investigated 34 resected stage III NSCLC pa...

journal_title：Experimental and therapeutic medicine

authors： Huang CL,Kadota K,Liu D,Ueno M,Nakasima N,Ishikawa S,Gotoh M,Misaki N,Chang SS,Yokomise H

更新日期：2010-05-01 00:00:00

abstract：:Periprosthetic joint infection (PJI) is a devastating condition and Staphylococcus spp. are the predominant pathogens responsible, particularly coagulase-negative staphylococci (CoNS) and Staphylococcus aureus. The aim of the present systematic review was to evaluate the distribution characteristics of specific Staphy...

journal_title：Experimental and therapeutic medicine

authors： Guo G,Wang J,You Y,Tan J,Shen H

更新日期：2017-06-01 00:00:00

abstract：:3-Hydroxy-3-methylglutaric aciduria (3-HMG, OMIN 246450) is a rare autosomal recessive metabolic disorder caused by a deficiency of 3-hydroxy-3-methylglutaryl-CoA lyase, a key enzyme in leucine metabolism and ketone body synthesis. Acute episodes of 3-HMG may be triggered by fasting or infection, and symptoms include ...

journal_title：Experimental and therapeutic medicine

authors： Hao X,Wang J,Liu S,Chen Y,Zhang Y,Hao Y

更新日期：2016-06-01 00:00:00

abstract：:The present study aimed to investigate changes in the levels of metabolites and appetite control factors caused by different dietary interventions in Sprague Dawley (SD) rats. A total of 35 male SD rats were weaned and immediately randomly assigned to five groups. The control group was given ad libitum access to a nor...

journal_title：Experimental and therapeutic medicine

authors： Lin B,Liu Y,Zhang W,Zou W

更新日期：2020-09-01 00:00:00

abstract：:The aim of the present study was to evaluate the expression of vascular endothelial growth factor (VEGF) and hypoxia inducible factor-1 (HIF-1), and to investigate the role of the HIF-1/VEGF signaling pathway following spinal cord injury (SCI). A total of 90 12-week-old Sprague Dawley rats were randomly divided into t...

journal_title：Experimental and therapeutic medicine

authors： Chen H,Li J,Liang S,Lin B,Peng Q,Zhao P,Cui J,Rao Y

更新日期：2017-03-01 00:00:00

abstract：:The aim of the present study was to investigate whether magnolol, the essential component of the traditional Chinese medicine, Magnolia officinalis, can pass through liver X receptor α (LXRα), to subsequently play an important role in the lipid metabolic balance. Using a HepG2 human hepatoma cell line, mammalian cellu...

journal_title：Experimental and therapeutic medicine

authors： Xie NA,Hu C,Guo A,Liang H,DU P,Yin G

更新日期：2015-05-01 00:00:00

abstract：:Steroid-induced avascular necrosis of the femoral head (SANFH) is a mainly bilateral complication of steroid therapy that involves extensive necrosis, and frequently occurs in young and middle-aged individuals, with a high disability rate. Autophagy is an intracellular lysosomal degradation process occurring in numero...

journal_title：Experimental and therapeutic medicine

authors： Li X,Li YS,Li LJ,Xie X,Yang Y,Deng ZH,Zeng C,Lei GH

更新日期：2017-07-01 00:00:00

abstract：:The aim of the present study was to investigate the safety of tirofiban alone and in combination with various treatments in acute ischemic stroke (AIS). A total of 120 patients with AIS were included in the study, and these patients were divided into three treatment groups: Group A (tirofiban alone, n=68), group B (ti...

journal_title：Experimental and therapeutic medicine

authors： Zhu YQ,Zhang YJ,Ruan HL,Liu Q,Zhan Q,Li Q

更新日期：2015-07-01 00:00:00

abstract：:The inactivation of the cyclin-dependent kinase inhibitor p16(INK4A) gene by hypermethylation is observed in numerous types of cancer. New findings indicate that DNA and histone methylation act in concert in gene silencing. In this study, we investigated the methylation status of the p16(INK4A) gene promoter and the h...

journal_title：Experimental and therapeutic medicine

authors： Yoruker EE,Mert U,Bugra D,Yamaner S,Dalay N

更新日期：2012-11-01 00:00:00

abstract：:The present study aimed to apply the best single-energy (SE) scanning in energy spectrum computed tomography (CT) to evaluate the usefulness of lower extremity arterial angiography imaging in patients with lower extremity arterial occlusive disease. A total of 64 patients diagnosed with lower extremity arterial occlus...

journal_title：Experimental and therapeutic medicine

authors： Wang G,Zhao D,Ling Z,Wang H,Yu S,Zhang J

更新日期：2019-08-01 00:00:00

abstract：:Icariin (ICA), the main active flavonoid glucoside isolated from Herba Epimedii, has been shown to prevent postmenopausal bone loss in vitro. However, the mechanisms by which ICA prevents bone loss in vivo remain poorly understood. In the present study, the effect of ICA in an ovariectomized (OVX) rat model of osteopo...

journal_title：Experimental and therapeutic medicine

authors： Chen G,Wang C,Wang J,Yin S,Gao H,Xiang LU,Liu H,Xiong Y,Wang P,Zhu X,Yang LI,Zhang R

更新日期：2016-07-01 00:00:00

abstract：:Following spinal cord injury in rats, FK506 is able to protect local nerve tissue, promote neural regeneration, reduce neuronal apoptosis and accelerate the recovery of spinal cord functions. Nerve growth factor (NGF) is important in the regulation of central and peripheral nerve cell regeneration, growth differentiat...

journal_title：Experimental and therapeutic medicine

authors： Chen G,Zhang Z,Wang S,Lv D

更新日期：2013-10-01 00:00:00

abstract：:B-cell lymphoma 6 (BCL6), a proto-oncogene, is an evolutionarily conserved zinc finger protein that functions as a transcriptional repressor. BCL6 is the master regulator of B-lymphocyte development, and it has been reported that BCL6 may serve an important role in breast cancer progression. The aim of the present stu...

journal_title：Experimental and therapeutic medicine

authors： Ang L,Zheng L,Wang J,Huang J,Hu HG,Zou Q,Zhao Y,Liu QM,Zhao M,Wu ZS

更新日期：2017-11-01 00:00:00

abstract：:Cisplatin (DDP) is a commonly used chemotherapy drug; however, the side effects associated with its use, particularly acute kidney injury (AKI), limit its clinical application. Puerarin is a natural flavonoid extracted from the Chinese medical herb Radix puerariae, which has been reported to alleviate DDP-induced neph...

journal_title：Experimental and therapeutic medicine

authors： Wu Z,Li C,Li Q,Li J,Lu X

更新日期：2020-10-01 00:00:00

abstract：:Microendoscopic discectomy (MED) is an established procedure used to treat lumbar central spinal stenosis (LCSS) and lateral recess stenosis (LRS). The Interlaminar Endoscopic Surgical System iLESSYS® Delta approach has been developed from the traditional interlaminar endoscopic technique for the treatment of LCSS and...

journal_title：Experimental and therapeutic medicine

authors： Wu B,Xiong C,Tan L,Zhao D,Xu F,Kang H

更新日期：2020-12-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a progressive disease with a high mortality rate. Previous studies have revealed the important function of the β3 adrenergic receptor (β3-AR) in cardiovascular diseases, and the potential beneficial effects of numerous β3-AR agonists on pulmonary vasodilation. Conversely, a num...

journal_title：Experimental and therapeutic medicine

authors： Sun J,Cheng J,Ding X,Chi J,Yang J,Li W

更新日期：2020-01-01 00:00:00

abstract：:Atherosclerosis is caused by various factors, and Glabridin may have protective effects on the cardiovascular system. The purpose of the present study was to evaluate the effects of Glabridin on atherosclerosis and evaluate whether Glabridin attenuates arteriosclerosis and endothelial permeability by suppressing the m...

journal_title：Experimental and therapeutic medicine

authors： Wang G,Sun G,Wang Y,Yu P,Wang X,Zhou B,Zhu H

更新日期：2019-01-01 00:00:00

abstract：:The present investigation explored the in vitro culture, isolation and characterization of hair follicle cell differentiation from umbilical cord blood mesenchymal stem cells (MSCs). Flow cytometry was used to obtain MSCs from the isolation and purification of human umbilical cord blood MSCs. Culture suspension of hai...

journal_title：Experimental and therapeutic medicine

authors： Bu ZY,Wu LM,Yu XH,Zhong JB,Yang P,Chen J

更新日期：2017-07-01 00:00:00