Local steroid injection versus wrist splinting for carpal tunnel syndrome: A randomized clinical trial.

Abstract:

AIM:We conducted a prospective randomized parallel clinical trial comparing the efficacy of local steroid injection and nocturnal wrist splinting in patients with carpal tunnel syndrome (CTS). METHODS:The well-validated and disease-specific Boston Carpal Tunnel Questionnaire (BCTQ) was employed and its score at 4 weeks after treatment was used as the primary outcome measure. Important secondary outcomes included patient satisfaction, the change of an objective finger dexterity test and the side effects. RESULTS:Twenty-five patients in the local steroid group and 25 patients in the wrist splinting group completed the study procedures. At 4 weeks after treatment, there was significant improvement of the BTCQ scores in both the steroid group and splinting group. There was improvement of the finger dexterity test only in the steroid group but not in the splinting group. However, there was no statistically significant difference in the changes of BTCQ scores between the two groups after treatment. Patient satisfaction score was higher in the steroid group. Patients in the steroid group took fewer painkillers after treatment. Four patients developed side effects after splinting and three after local steroid injection, which was not statistically significant. CONCLUSION:Although local steroid injection and nocturnal wrist splinting were equally effective in the treatment of patients with CTS, only the former improved objective hand function. Local steroid injection also resulted in better patient satisfaction and less painkiller use without causing more side effects.

journal_name

Int J Rheum Dis

authors

So H,Chung VCH,Cheng JCK,Yip RML

doi

10.1111/1756-185X.13162

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

102-107

issue

1

eissn

1756-1841

issn

1756-185X

journal_volume

21

pub_type

杂志文章,随机对照试验
  • Risk of hepatitis B reactivation in patients receiving anti-tumor necrosis factor-α therapy.

    abstract:OBJECTIVE:The purpose of this study was to determine hepatitis B virus (HBV) screening rates in patients receiving anti-tumor necrosis factor (TNF)-α therapy and the frequency of HBV reactivation in patients with resolved hepatitis B virus infection (hepatitis B surface antigen [HBsAg] negative, hepatitis B core antibo...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.14034

    authors: Fidan S,Capkın E,Arıca DA,Durak S,Okatan IE

    更新日期:2021-02-01 00:00:00

  • Effects of Arctium lappa L. (Burdock) root tea on inflammatory status and oxidative stress in patients with knee osteoarthritis.

    abstract:AIM:This study was designed to examine the effect of Burdock root tea on inflammatory markers and oxidative stress indicators in patients with knee osteoarthritis (OA). METHODS:Thirty-six patients (10 men and 26 women) aged 50-70 years old with knee osteoarthritis referred to the Physical Medicine and Rehabilitation D...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/1756-185X.12477

    authors: Maghsoumi-Norouzabad L,Alipoor B,Abed R,Eftekhar Sadat B,Mesgari-Abbasi M,Asghari Jafarabadi M

    更新日期:2016-03-01 00:00:00

  • Association between chest computed tomography findings and respiratory adverse events in rheumatoid arthritis patients undergoing long-term biological therapy.

    abstract:OBJECTIVE:This study aimed to assess the association between chest computed tomography (CT) findings and incidence of respiratory adverse events (RAEs), and to detect risk factors for RAEs, in RA patients treated with long-term biological therapy. METHODS:Clinical and radiological data of 332 RA patients who were trea...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13434

    authors: Matsumoto T,Iwano S,Takahashi N,Asai S,Watanabe T,Asai N,Sobue Y,Ito S,Ishiguro N,Kojima T

    更新日期:2019-04-01 00:00:00

  • Pilot study assessing the novel use of musculoskeletal ultrasound in patients with rheumatoid arthritis to improve patient attitudes and adherence to medication.

    abstract:OBJECTIVE:To determine if showing patients with rheumatoid arthritis (RA) ultrasound (US) images of their inflamed joints: (i) increased belief in the necessity of medication; (ii) encouraged patient activation, that is, confidence and understanding in managing their health; and (iii) facilitated medication adherence. ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12402

    authors: Joplin SK,van der Zwan R,Bagga H,Joshua F,Wong PK

    更新日期:2016-07-01 00:00:00

  • LncRNA GAS5 activates the AMPK pathway in peripheral blood mononuclear cells derived from rheumatoid arthritis patients.

    abstract:BACKGROUND:Rheumatoid arthritis (RA) is an inflammatory disease, which seriously affects human joints. This study aimed to detect the changes in the expression of long non-coding RNA growth arrest-specific transcript 5 (GAS5) in peripheral blood mononuclear cells (PBMCs) derived from patients with RA and healthy contro...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13930

    authors: Cao J,Lv X,Zhang Y,Xu A,Jiang T

    更新日期:2020-08-04 00:00:00

  • Total hip arthroplasty in patients with chronic autoimmune inflammatory arthroplasties.

    abstract:OBJECTIVE:Patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and ankylosing spondylitis (AS) often require total hip arthroplasties. We present a retrospective review of 32 total hip arthroplasties (THA) performed for patients with SLE, RA or AS from 2003 to 2008 in a tertiary hospital in Singa...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2010.01477.x

    authors: Chong RW,Chong CS,Lai CH

    更新日期:2010-08-01 00:00:00

  • The Gouty Joseph in Giulio Romano's 'Holy Family'.

    abstract::Joint diseases in antiquity and the Renaissance were generally known by the all-encompassing term, gout (podagra or gotta). Only in later centuries was there a differentiation in the types of joint diseases, distinguishing gout in the modern sense from other arthritic and rheumatic disorders. The present article illus...

    journal_title:International journal of rheumatic diseases

    pub_type: 传,历史文章,杂志文章

    doi:10.1111/j.1756-185X.2011.01622.x

    authors: Weisz GM,Albury WR,Lippi D,Matucci-Cerinic M

    更新日期:2011-08-01 00:00:00

  • Clinical profile of Filipino patients with osteoarthritis seen at two arthritis clinics.

    abstract:AIM:To describe a cohort of Filipinos with primary osteoarthritis (OA). METHOD:Charts with diagnosis of OA from two arthritis clinics (Philippine General Hospital and a private clinic) from January 2008 to May 2011, were reviewed for demographics, clinical presentation, risk factors and management. Descriptive statist...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2012.01758.x

    authors: Racaza GZ,Salido EO,Penserga EG

    更新日期:2012-08-01 00:00:00

  • Measuring bone density in axial spondyloarthropathy: Time to turn things on their side?

    abstract:AIM:Osteoporosis in axial spondyloarthropathy (axSpA) is difficult to accurately diagnose due to osteoproliferation of the spine interfering with conventional (anteroposterior, AP) dual-energy X-ray absorptiometry (DXA). This study compares AP and lateral projections of DXA when assessing bone mineral density (BMD) of ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1111/1756-185X.13765

    authors: Fitzgerald G,Anachebe T,McCarroll K,O'Shea F

    更新日期:2020-03-01 00:00:00

  • Efficacy and safety of tofacitinib in patients with active rheumatoid arthritis: review of key Phase 2 studies.

    abstract::Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Here, the safety and efficacy data from five Phase 2 studies of tofacitinib in patients with RA are summarized. Tofacitinib 1-30 mg twice daily was investigated, as monotherapy and in combination with methotrexate, in patient...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/1756-185X.12901

    authors: Fleischmann R,Kremer J,Tanaka Y,Gruben D,Kanik K,Koncz T,Krishnaswami S,Wallenstein G,Wilkinson B,Zwillich SH,Keystone E

    更新日期:2016-12-01 00:00:00

  • Cadmium, one of the villains behind the curtain: has exposure to cadmium helped to pull the strings of seropositive rheumatoid arthritis pathogenesis all along?

    abstract::Exposure to cadmium links smoking, the most import antetiological factor in the development of seropositive RA, and many of the other known contemporary risk factors. Epidemiological studies investigating the link between smoking, occupations, social class, region of residency and RA should consider cadmium exposure a...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12673

    authors: Hutchinson D

    更新日期:2015-06-01 00:00:00

  • The association between P selectin glycoprotein ligand 1 gene variable number of tandem repeats polymorphism and risk of thrombosis in Behçet's disease.

    abstract:OBJECTIVES:Behçet's disease (BD) has been recognized as an unclassified type of vasculitis with an accompanying tendency to thrombosis. No disease-specific pathology has been demonstrated so far to explain the prothrombotic state, and this predisposition is considered to be associated with endothelial activation/dysfun...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13151

    authors: Cosan F,Oku B,Gedar Totuk OM,Abaci N,Ustek D,Diz Kucukkaya R,Gul A

    更新日期:2018-12-01 00:00:00

  • Gout: an Asia-Pacific update.

    abstract::Even though, Hippocrates recognized gout as an affection of older men and a product of high living long back in 5th century BC, this painful condition promises to accompany humanity to the 21st century. The incidence is progressively rising and females are also affected in the modern era. There are also regional and e...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/1756-185X.13103

    authors: Paul BJ,James R

    更新日期:2017-04-01 00:00:00

  • The Role of 18F Fluorodeoxyglucose Positron Emission Tomography Scanning in the Diagnosis and Management of Systemic Vasculitis.

    abstract::Primary systemic vasculitis is a group of heterogeneous disorders, characterized by inflammation of blood vessels causing end organ damage from ischemia, aneurysm formation or dissection. Delay in the early diagnosis owing to non-specific symptoms, lack of definitive serological tests, limited availability of biopsy a...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/1756-185X.12713

    authors: Danve A,O'Dell J

    更新日期:2015-09-01 00:00:00

  • Body mass index and hand osteoarthritis susceptibility: an updated meta-analysis.

    abstract:AIM:Numerous epidemiologic studies have evaluated the association between overweight and hand osteoarthritis; However, the existing results are inconsistent. METHODS:Systematic searches were performed and reference lists from the retrieved trials were searched. This meta-analysis and meta-regression was executed to id...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/1756-185X.12895

    authors: Jiang L,Xie X,Wang Y,Wang Y,Lu Y,Tian T,Chu M,Shen Y

    更新日期:2016-12-01 00:00:00

  • No increased risk of herpes zoster in TNF inhibitor and non-TNF inhibitor users with rheumatoid arthritis: epidemiological study using the Japanese health insurance database.

    abstract:OBJECTIVE:It is controversial whether the use of biological disease-modifying antirheumatic drugs (DMARDs) increases the risk of herpes zoster (HZ). We aimed to evaluate the risks of HZ in tumor necrosis factor inhibitor (TNFI) and non-TNFI users with rheumatoid arthritis (RA) over 3 years in Japan. METHOD:Using the J...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13300

    authors: Sakai R,Kasai S,Hirano F,Harada S,Kihara M,Yokoyama W,Tsutsumino M,Nagasaka K,Koike R,Yamanaka H,Miyasaka N,Harigai M

    更新日期:2018-09-01 00:00:00

  • Association between COX-2 and 15-PGDH polymorphisms and SLE susceptibility.

    abstract:AIMS:Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease. Prostaglandins E2 (PGE2), the product of the cyclo-oxygenase 2 (COX-2) enzyme, has critical roles in the etiology of autoimmune diseases. PGE2 level is controlled by a balance between its synthesis mediator (COX-2 enzyme) and its cata...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13808

    authors: Sandoughi M,Saravani M,Rokni M,Nora M,Mehrabani M,Dehghan A

    更新日期:2020-05-01 00:00:00

  • Systemic lupus erythematosus complicated with posterior reversible encephalopathy syndrome and intracranial vasculopathy.

    abstract::Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic condition characterized by reversible vasogenic edema on neuroimaging. It is associated with various neurological manifestations, including headaches, vomiting, seizures, visual loss, altered mental status and focal neurological deficits. PRES mainly ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2010.01545.x

    authors: Chen HA,Lin YJ,Chen PC,Chen TY,Lin KC,Cheng HH

    更新日期:2010-10-01 00:00:00

  • Differential expression of natural killer activating and inhibitory receptors in patients with newly diagnosed systemic lupus erythematosus.

    abstract:AIM:Systemic lupus erythematosus (SLE) presents as the abnormal activation and over-proliferation of immune competent cells. Few studies have characterized the role of natural killer (NK) and NK T (NKT) cells in the pathogenesis of SLE, and therefore a consensus has not been reached as yet. METHOD:Thirty-two patients ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12289

    authors: Ye Z,Ma N,Zhao L,Jiang ZY,Jiang YF

    更新日期:2016-06-01 00:00:00

  • IL10 low-frequency variants in Behçet's disease patients.

    abstract:AIM:To explain the missing heritability after the genome-wide association studies era, sequencing studies allow the identification of low-frequency variants with a stronger effect on disease risk. Common variants in the interleukin 10 gene (IL10) have been consistently associated with Behçet's disease (BD) and the goal...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1111/1756-185X.12369

    authors: Matos M,Xavier JM,Abrantes P,Sousa I,Rei N,Davatchi F,Shahram F,Jesus G,Barcelos F,Vedes J,Salgado M,Abdollahi BS,Nadji A,Moraes-Fontes MF,Shafiee NM,Ghaderibarmi F,Vaz Patto J,Crespo J,Oliveira SA

    更新日期:2017-05-01 00:00:00

  • Superiority of laterally elevated wedged insoles to neutrally wedged insoles in medial knee osteoarthritis symptom relief.

    abstract:AIM:Knee osteoarthritis (OA), is the most common degenerative joint disease. Several non-pharmacological interventions have been used for this purpose such as insoles. There are contradictory data about the superiority and effectiveness of laterally wedged compared with neutrally wedged insoles. This study was designed...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/1756-185X.12036

    authors: Hatef MR,Mirfeizi Z,Sahebari M,Jokar MH,Mirheydari M

    更新日期:2014-01-01 00:00:00

  • A retrospective study on 158 Thai patients with juvenile idiopathic arthritis followed in a single center over a 15-year period.

    abstract:AIM:To determine the outcomes of juvenile idiopathic arthritis (JIA) in Thai children. METHODS:A retrospective cohort study. All JIA patients in a rheumatology clinic, Ramathibodi Hospital, between July 1997 and December 2012 were enrolled. The patient data were reviewed from medical records. At the most recent follow...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12637

    authors: Vilaiyuk S,Soponkanaporn S,Jaovisidha S,Benjaponpitak S,Manuyakorn W

    更新日期:2016-12-01 00:00:00

  • Role of glucocorticoids in Kawasaki disease.

    abstract::Although treatment with intravenous immunoglobulin (IVIg) with aspirin is the standard of care for children with Kawasaki disease (KD), 15-20% of patients fail to respond and experience persistent or recurrent fever after completion of IVIg administration. These IVIg non-responders are at high risk for coronary artery...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章,评审

    doi:10.1111/1756-185X.13209

    authors: Miura M

    更新日期:2018-01-01 00:00:00

  • Prognosis, complications and treatment response in systemic juvenile idiopathic arthritis patients: A single-center experience.

    abstract:AIM:Systemic juvenile idiopathic arthritis (sJIA) is a distinctive subtype of JIA characterized by systemic features and poor outcome. We aimed to investigate demographic and clinical features, long-term treatment response and disease complications in a large sJIA cohort. METHODS:Patients diagnosed with sJIA followed ...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13649

    authors: Barut K,Adrovic A,Sahin S,Tarcin G,Tahaoglu G,Koker O,Yildiz M,Kasapcopur O

    更新日期:2019-09-01 00:00:00

  • Health-related quality of life in rheumatoid arthritis: Systematic review and meta-analysis of EuroQoL (EQ-5D) utility scores from Asia.

    abstract:INTRODUCTION:Region-specific health-related quality of life (HRQoL) scores or utility values are representative and pivotal for economic evaluations as they are influenced by the value judgment of the local population. This study systematically reviewed and pooled EuroQoL-5 Dimension (EQ-5D) utility scores of rheumatoi...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.14066

    authors: Haridoss M,Bagepally BS,Natarajan M

    更新日期:2021-01-23 00:00:00

  • Histological analysis of synovium by treatment of etanercept for rheumatoid arthritis.

    abstract:AIMS:In order to investigate the histological change in effect attenuation cases of etanercept compared with methotrexate (MTX), we performed immunohistochemical examination by seven different molecules. METHODS:We histologically assessed synovial tissue from five MTX-treated rheumatoid arthritis (RA) patients as cont...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/j.1756-185X.2009.01372.x

    authors: Suzuki Y,Inoue K,Chiba J,Inoue Y,Kanbe K

    更新日期:2009-04-01 00:00:00

  • Associations between blood lead, cadmium, and mercury levels with hyperuricemia in the Korean general population: A retrospective analysis of population-based nationally representative data.

    abstract:AIM:An elevated serum uric acid level is associated with various diseases, such as gout, hypertension, renal impairment, and diabetes. Heavy metals, including lead and cadmium, are suspected to increase serum uric acid levels, but evidence regarding this is not sufficient, particularly in the Asian population. Therefor...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13632

    authors: Jung W,Kim Y,Lihm H,Kang J

    更新日期:2019-08-01 00:00:00

  • Effect of total knee arthroplasty on other joints in patients with rheumatoid arthritis evaluated by 18-FDG-PET.

    abstract:AIM:The objective of this study was to assess arthritis of the whole body before and after total knee arthroplasty (TKA) in patients with rheumatoid arthritis (RA) using positron emission tomography (PET). METHOD:Seventeen knees of 17 RA patients (median age 68 years) who underwent TKA were included in this study. Cli...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12855

    authors: Yonemoto Y,Okamura K,Kaneko T,Okura C,Kobayashi T,Suto T,Tsushima Y,Takagishi K

    更新日期:2017-06-01 00:00:00

  • Systemic sclerosis and malignancy.

    abstract:BACKGROUND:Systemic sclerosis (SSc) has increased risk of morbidity and mortality due to pulmonary fibrosis, pulmonary arterial hypertension, renal crisis, infections and malignancies. Chemical exposure, smoking and cytotoxic drugs increase the malignancy risk in rheumatic diseases including SSc. We aim to evaluate cha...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.13311

    authors: Sargin G,Senturk T,Cildag S

    更新日期:2018-05-01 00:00:00

  • Adiponectin: is it a biomarker for assessing the disease severity in knee osteoarthritis patients?

    abstract:AIM:The results of previous studies regarding the role of adiponectin in the pathogenesis of osteoarthritis (OA) are controversial. The aim of this study is to investigate the relation of plasma adiponectin levels with clinical and radiological disease severity in knee OA patients. METHOD:Sixty patients with knee OA a...

    journal_title:International journal of rheumatic diseases

    pub_type: 杂志文章

    doi:10.1111/1756-185X.12790

    authors: Cuzdan Coskun N,Ay S,Evcik FD,Oztuna D

    更新日期:2017-12-01 00:00:00