Efficacy and safety of tofacitinib in patients with active rheumatoid arthritis: review of key Phase 2 studies.

abstract：AIM:The use of healthcare resources by rheumatoid arthritis (RA) patients can be related to the presence of disease, comorbid conditions, use of steroids, and the combined use of immunosuppressants. This study evaluated the risk factors associated with infection and hospitalization in RA. METHODS:This multicenter, cro...

journal_title：International journal of rheumatic diseases

authors： Chandrashekara S,Shobha V,Dharmanand BG,Jois R,Kumar S,Mahendranath KM,Haridas V,Prasad S,Singh Y,Daware MA,Swamy A,Subramanian R,Somashekar SA,Shanthappa AM,Anupama KR

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the disease activity and current pharmacological interventions used to achieve remission in rheumatoid arthritis (RA) patients in Australia. METHODS:Rheumatoid arthritis patients treated in participating Australian clinics were included in the study. Patient demographics, disease onset, medicati...

journal_title：International journal of rheumatic diseases

authors： Littlejohn G,Roberts L,Arnold M,Bird P,Burnet S,de Jager J,Griffiths H,Nicholls D,Scott J,Zochling J,Tymms KE

更新日期：2013-10-01 00:00:00

abstract：AIMS:Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease. Prostaglandins E2 (PGE2), the product of the cyclo-oxygenase 2 (COX-2) enzyme, has critical roles in the etiology of autoimmune diseases. PGE2 level is controlled by a balance between its synthesis mediator (COX-2 enzyme) and its cata...

journal_title：International journal of rheumatic diseases

authors： Sandoughi M,Saravani M,Rokni M,Nora M,Mehrabani M,Dehghan A

更新日期：2020-05-01 00:00:00

abstract：AIM:This study investigated the prognostic factors of cardiac death or cardiac failure using cardiac scintigraphy, echocardiography (UCG), and magnetic resonance imaging (MRI) in asymptomatic systemic sclerosis (SSc) patients. METHODS:We retrospectively evaluated SSc patients who had undergone cardiac scintigraphy usi...

journal_title：International journal of rheumatic diseases

authors： Iida H,Hanaoka H,Okada Y,Kiyokawa T,Takakuwa Y,Yamada H,Okazaki T,Ozaki S,Yamaguchi K,Nakajima Y,Kawahata K

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety of tumor necrosis factor-α (TNF-α) monoclonal antibody (infliximab) therapy in patients with rheumatoid arthritis (RA) and previous exposure to hepatitis B virus (HBV) who had normal liver function. METHODS:This is a retrospective study from a 26-week, prospective, multicenter trial in...

journal_title：International journal of rheumatic diseases

authors： Zhang X,Zhang F,Wu D,Bao C,Zhu P,Zhang X,Huang C,He D,Tao Y,Fang Y,Gu J,Wu H,Sun L,Yang X,Huang F,Xu H,Zhao D,Zhang M,Zheng Y,Li Z

更新日期：2013-08-01 00:00:00

abstract：AIM:To determine the outcomes of juvenile idiopathic arthritis (JIA) in Thai children. METHODS:A retrospective cohort study. All JIA patients in a rheumatology clinic, Ramathibodi Hospital, between July 1997 and December 2012 were enrolled. The patient data were reviewed from medical records. At the most recent follow...

journal_title：International journal of rheumatic diseases

authors： Vilaiyuk S,Soponkanaporn S,Jaovisidha S,Benjaponpitak S,Manuyakorn W

更新日期：2016-12-01 00:00:00

abstract：:Loss of B-cell tolerance is a hallmark feature of the pathogenesis in systemic lupus erythematosus (SLE), an autoimmune disease that is characterized by hypergammaglobulinemia and autoantibody production. These autoantibodies lead to formation of immune-complex deposition in internal organs causing inflammation and da...

journal_title：International journal of rheumatic diseases

authors： Mok MY

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of vitamin D inadequacy in a group of Filipino post-menopausal women with osteoporosis. METHODS:Seventy otherwise healthy post-menopausal Filipino women seen at the University of Santo Tomas Hospital, Section of Rheumatology, were diagnosed with osteoporosis by central dual-energy...

journal_title：International journal of rheumatic diseases

authors： Raso AA,Navarra SV,Li-Yu J,Torralba TP

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To investigate the association of core stability with physical function and functional performance in patients with systemic sclerosis (SSc). METHODS:Forty patients who met the American College of Rheumatology / European League Against Rheumatism 2013 classification criteria for SSc were included in the cros...

journal_title：International journal of rheumatic diseases

authors： Yakut H,Özalevli S,Birlik AM

更新日期：2021-01-19 00:00:00

abstract：AIM:To evaluate the prevalence and severity of periodontal disease in patients with rheumatoid arthritis (RA) who attended a rheumatology clinic in a university hospital. METHODS:All consecutive patients with RA who attended the rheumatology clinic between June 2009 and January 2010 were asked to enroll in this study....

journal_title：International journal of rheumatic diseases

authors： Khantisopon N,Louthrenoo W,Kasitanon N,Sivasomboon C,Wangkaew S,Sang-In S,Jotikasthira N,Bandhaya P

更新日期：2014-06-01 00:00:00

abstract：AIM:This study aimed to evaluate the relationship between circulating adiponectin and visfatin levels and rheumatoid arthritis (RA) and to establish a correlation between serum adipokine levels and RA activity. METHODS:We conducted meta-analyses on serum/plasma adiponectin or visfatin levels in patients with RA and co...

journal_title：International journal of rheumatic diseases

authors： Lee YH,Bae SC

更新日期：2018-03-01 00:00:00

abstract：AIM:Pulmonary arterial hypertension (PAH) is a complex and devastating complication of systemic lupus erythematosus (SLE). We sought to describe the baseline characteristics of right heart catheterization (RHC)-confirmed SLE-associated PAH and identify risk factors for PAH in SLE patients. METHODS:A multicenter, cross...

journal_title：International journal of rheumatic diseases

authors： Zhang N,Li M,Qian J,Wang Q,Zhao J,Yang Z,Tian Z,Zhang X,Zuo X,Zhang M,Zhu P,Ye S,Zhang W,Zheng Y,Qi W,Li Y,Zhang Z,Ding F,Gu J,Liu Y,Wei W,Zeng X

更新日期：2019-05-01 00:00:00

abstract：AIM:Systemic lupus erythematosus (SLE) is an autoimmune disease that is associated with genetic and environmental factors and microbial infection. With respect to microbial infection, the Epstein-Barr virus (EBV) has been a widely discussed issue in recent decades. Human herpesvirus 8 (HHV-8) belongs to the same γ-herp...

journal_title：International journal of rheumatic diseases

authors： Tung YC,Ke LY,Tsai SM,Lu PL,Tsai WC

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:Remission is an ideal target in the management of rheumatoid arthritis (RA). We compared American College of Rheumatology (ACR) 1981 preliminary definition of remission, European League Against Rheumatism (EULAR) disease activity score of 28 joints - C-reactive protein (DAS28 (3)-CRP) and DAS28 (3)-ESR (eryth...

journal_title：International journal of rheumatic diseases

authors： Chandrashekara S,Priyanka BU

更新日期：2013-06-01 00:00:00

abstract：AIM:To describe the clinical features, treatment and long-term outcomes in north Indian patients with granulomatosis with polyangiitis (GPA). METHODS:Clinical details, Birmingham Vasculitis Activity Score (BVAS-v3), laboratory data, histopathology findings, treatment details and outcomes of all consecutive patients di...

journal_title：International journal of rheumatic diseases

authors： Sharma A,Naidu GSRSNK,Rathi M,Verma R,Modi M,Pinto B,Sharma K,Dhir V,Singhal M,Prakash M,Nada R,Panda NK,Minz RW

更新日期：2018-01-01 00:00:00

abstract：:Psoriatic arthritis (PsA) is a common, chronic inflammatory disease with complex pathogenesis. In recent years, a number of susceptibility non-human leukocyte antigen (HLA) genes of PsA have been revealed, which also act as important factors in the pathogenesis of PsA as well as HLA genes. By searching the databases N...

journal_title：International journal of rheumatic diseases

authors： Chen J,Yuan F,Fan X,Wang Y

更新日期：2020-08-06 00:00:00

abstract：AIM:To study the profile of autoantibodies on long-term follow-up of children with Kawasaki disease (KD). PATIENTS AND METHODS:In this single-center observational cohort study, 50 children who had been diagnosed and treated for KD with a minimum follow-up period of 3 years were enrolled. The organ-specific autoantibod...

journal_title：International journal of rheumatic diseases

authors： Basha A,Rawat A,Jindal AK,Gupta A,Anand S,Garg R,Minz RW,Singh S

更新日期：2018-11-01 00:00:00

abstract：:We discuss recent and prospective research in small and large vessel vasculitis. Large cohorts of Takayasu arteritis (TA) have been recently published from across the world, clarifying our understanding of this uncommon disease. Novel open-ended approaches like large-scale genotyping, proteomics and metabolomics have ...

journal_title：International journal of rheumatic diseases

authors： Misra DP,Naidu GSRSNK,Agarwal V,Sharma A

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Kawasaki disease (KD) is an acute systemic vasculitis. Activation of the immune system is a central feature of KD. Some KD patients are resistant to initial high-dose intravenous immunoglobulin (IVIG) treatment. The study aimed to determine the predictors of IVIG resistance. METHOD:A single-center, retrospe...

journal_title：International journal of rheumatic diseases

authors： Sato S,Kawashima H,Kashiwagi Y,Hoshika A

更新日期：2013-04-01 00:00:00

abstract：AIM:Inflammatory joint diseases (IJDs) are chronic arthritis, but frequently present with co-morbidities of other organs and systems, which is known as extra-articular manifestations (EAMs). It is still unclear which clinical characteristics or bio-markers can predict the development of EAMs. The aim of this study was ...

journal_title：International journal of rheumatic diseases

authors： Yan S,Cui Y,Zhang X,Zhang G,Dong G,Feng Y,Song Y

更新日期：2019-09-01 00:00:00

abstract：AIM:Colchicine prophylaxis is the single most important factor in ameliorating familial Mediterranean fever (FMF) for the prevention of both attacks and secondary amyloidosis. The aim of the present study was to evaluate the exact proportion of those patients who do not respond to colchicine and to characterize their d...

journal_title：International journal of rheumatic diseases

authors： Melikoglu MA,Senel K

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:To measure serial interleukin (IL)-6 levels in newly diagnosed patients with giant cell arteritis (GCA), treated in a randomized controlled trial of modified-release prednisone (MR) vs immediate-release prednisolone (IR) used in a tapering regimen conforming to British Society for Rheumatology GCA guidelines...

journal_title：International journal of rheumatic diseases

authors： Miler E,Stapleton PP,Mapplebeck S,Mackerness C,Gayford D,Aung T,Wilson L,Schofield P,Dasgupta B

更新日期：2019-10-01 00:00:00

abstract：AIM:To develop a translated and culturally adapted Bengali version of the WHO Fracture Risk Assessment Tool (FRAX(®) ) and to test its feasibility, content validity and reliability. METHOD:The English FRAX was translated and culturally adapted for use in Bangladeshi populations following established forward-backward t...

journal_title：International journal of rheumatic diseases

authors： Islam MN,Ferdous N,Ten Klooster PM,Uddin MS,Nasrin S,Pal B,Rasker JJ

更新日期：2015-03-01 00:00:00

abstract：:We report a rare case of antisynthase syndrome (ASS) complicated with Kaposi sarcoma, analyze its clinical characteristics, and review the literature on the topic. An 80-year-old male patient developed fever, cough, and shortness of breath. Lung high-resolution computed tomography showed nonspecific interstitial pneum...

journal_title：International journal of rheumatic diseases

authors： He N,Lu D,Xue J,Wang X

更新日期：2020-06-01 00:00:00

abstract：AIM:The aim of this article is two-fold: (i) to demonstrate the relation between vitamin D deficiency and dry eye and impaired tear function; and (ii) to investigate the possible associations among clinical parameters of hypovitaminosis D with dry eye parameters. METHOD:Fifty premenopausal women with vitamin D deficie...

journal_title：International journal of rheumatic diseases

authors： Yildirim P,Garip Y,Karci AA,Guler T

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine the effect of active immunization of interleukin (IL)-17A to inhibit B cell functions and monitor the risk of infection in a pristane-induced lupus mice model. METHODS:Female Balb/c mice were given a single intraperitoneal injection of 0.5 mL pristane. IL-17A was coupled ...

journal_title：International journal of rheumatic diseases

authors： Handono K,Pratama MZ,Sari DK,Hermawan HO,Agdana HM,Kawuningan KB,Nur'aini N,Hasanah D,Kalim H

更新日期：2018-06-01 00:00:00

abstract：AIM:In rheumatoid arthritis (RA) hands, we applied high-resolution peripheral quantitative computed tomography (HR-pQCT) and 3 Tesla (3 T) magnetic resonance imaging (MRI), which are new methods for erosion detection and bone marrow edema (BME) quantification. We compared the erosion measurements between these techniqu...

journal_title：International journal of rheumatic diseases

authors： Lee CH,Srikhum W,Burghardt AJ,Virayavanich W,Imboden JB,Link TM,Li X

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:It is controversial whether the use of biological disease-modifying antirheumatic drugs (DMARDs) increases the risk of herpes zoster (HZ). We aimed to evaluate the risks of HZ in tumor necrosis factor inhibitor (TNFI) and non-TNFI users with rheumatoid arthritis (RA) over 3 years in Japan. METHOD:Using the J...

journal_title：International journal of rheumatic diseases

authors： Sakai R,Kasai S,Hirano F,Harada S,Kihara M,Yokoyama W,Tsutsumino M,Nagasaka K,Koike R,Yamanaka H,Miyasaka N,Harigai M

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:To investigate the causes and risk of death in a large cohort of Korean patients with rheumatoid arthritis (RA). METHODS:Patients in the Hanyang BAE (Bae registry of Autoimmune diseases for Epidemiology) RA cohort who fulfilled the American College of Rheumatology criteria were analyzed. A total of 2355 pat...

journal_title：International journal of rheumatic diseases

authors： Lee YK,Ahn GY,Lee J,Shin JM,Lee TH,Park DJ,Song YJ,Kim MK,Bae SC

更新日期：2021-01-19 00:00:00

abstract：AIM:To review the clinical features of brachial synovial cyst. METHOD:A case of bilateral brachial synovial cysts is described in a child suffering from systemic juvenile idiopathic arthritis during a relapse. Magnetic resonance imaging and ultrasonography were conducted to further evaluate the nature of the cysts. Th...

journal_title：International journal of rheumatic diseases

authors： Zheng Q,Lu M

更新日期：2019-08-01 00:00:00