Abstract:
:Evolution of resistance threatens sustainability of transgenic crops producing insecticidal proteins from the bacterium Bacillus thuringiensis (Bt). The fall armyworm (Spodoptera frugiperda) is a devastating pest of corn in the Western Hemisphere initially controlled by transgenic Bt corn producing the Cry1Fa insecticidal protein (event TC1507). However field-evolved resistance to TC1507 was observed in Puerto Rico in 2007 and has subsequently been reported in a number of locations in North and South America. Early studies on Puerto Rico fall armyworm populations found that the resistance phenotype was associated with reduced expression of alkaline phosphatase. However, in this work we show that field-evolved resistance to Cry1Fa Bt corn in Puerto Rico is closely linked to a mutation in an ATP Binding Cassette subfamily C2 (ABCC2) gene that functions as a Cry1Fa receptor in susceptible insects. Furthermore, we report a DNA-based genotyping test used to demonstrate the presence of the resistant (SfABCC2mut) allele in Puerto Rico populations in 2007, coincident with the first reports of damage to TC1507 corn. These DNA-based field screening data provide strong evidence that resistance to TC1507 in fall armyworm maps to the SfABCC2 gene and provides a useful molecular marker for detecting the SfABCC2mut allele in resistant fall armyworm.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Banerjee R,Hasler J,Meagher R,Nagoshi R,Hietala L,Huang F,Narva K,Jurat-Fuentes JLdoi
10.1038/s41598-017-09866-ysubject
Has Abstractpub_date
2017-09-07 00:00:00pages
10877issue
1issn
2045-2322pii
10.1038/s41598-017-09866-yjournal_volume
7pub_type
杂志文章abstract::Standard electroporation with pulses in milliseconds has been used as an effective tool to deliver drugs or genetic probes into cells, while irreversible electroporation with nanosecond pulses is explored to alter intracellular activities for pulse-induced apoptosis. A combination treatment, long nanosecond pulses fol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63172-8
更新日期:2020-04-08 00:00:00
abstract::The mechanisms underlying bladder contractile disorders such as overactive bladder are not fully understood, and there is limited understanding of the receptor systems modulating spontaneous bladder contractions. We investigated the potential for histamine to have a role in mediating contractility of the urothelium wi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40384-1
更新日期:2019-03-07 00:00:00
abstract::To obtain high performance CH3NH3PbI3 perovskite solar cells, it is highly important to realise a high open-circuit voltage. Calculation results based on a modified diode model have indicated that a low bare ratio ϕ of the perovskite film is the most important factor determining the open-circuit voltage, where ϕ is de...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46141
更新日期:2017-04-12 00:00:00
abstract::Responses of ecosystems to human-induced stress vary in space and time, because both stressors and ecosystem vulnerabilities vary in space and time. Presently, ecosystem impact assessments mainly take into account variation in stressors, without considering variation in ecosystem vulnerability. We developed a method t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09573-8
更新日期:2017-08-24 00:00:00
abstract::This study investigated interactive effects of CYP2B6 genotypes and liver metastasis on the prognosis of metastatic breast cancer patients who received combined chemotherapy of docetaxel and thiotepa. Totally 153 patients were retrospectively genotyped rs8192719 (c.1294 + 53C > T) and rs2279343 (c.785A > G). Kaplan-Me...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/srep16775
更新日期:2015-11-25 00:00:00
abstract::What is intuitive: pro-social or anti-social behaviour? To answer this fundamental question, recent studies analyse decision times in game theory experiments under the assumption that intuitive decisions are fast and that deliberation is slow. These analyses keep track of the average time taken to make decisions under...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52359-3
更新日期:2019-11-19 00:00:00
abstract::Due to chromatic aberration, blue images are defocused when the eye is focused to the middle of the visible spectrum, yet we normally are not aware of chromatic blur. The eye suffers from monochromatic aberrations which degrade the optical quality of all images projected on the retina. The combination of monochromatic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79911-w
更新日期:2021-01-11 00:00:00
abstract::Our previous studies indicated that combination of Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and PPARγ ligand Troglitazone (TZD), can induce significant apoptosis in various TRAIL-resistant prostate and hepatocellular carcinoma (HCC) cells. These also suggested serine/threonine kinase AMP-activat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23780-x
更新日期:2018-04-03 00:00:00
abstract::Post-transplant cyclophosphamide has become a promising medical option after allogeneic HSCT. In this study we aimed to evaluate the efficacy of cyclophosphamide and cyclosporine combination in acute and chronic graft-versus-host disease (GvHD) prophylaxis in acute myeloid leukemia (AML) cases scheduled for allogeneic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38644-1
更新日期:2019-02-14 00:00:00
abstract::Blueberry juice is a healthy and nutritious food that has become increasingly popular worldwide. However, little is known about the microbial groups of this juice that can cause its spoilage. This study aimed to identify the main spoilage microorganisms in blueberry juice and explore whether a microchip pulsed electri...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-26513-2
更新日期:2018-05-25 00:00:00
abstract::Chronic suppurative otitis media (CSOM) is one of the most common infectious diseases of the middle ear especially affecting children, leading to delay in language development and communication. Although Staphylococcus aureus is the most common pathogen associated with CSOM, its interaction with middle ear epithelial ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47079-7
更新日期:2019-07-25 00:00:00
abstract::Attaching Unique Molecular Identifiers (UMI) to RNA molecules in the first step of sequencing library preparation establishes a distinct identity for each input molecule. This makes it possible to eliminate the effects of PCR amplification bias, which is particularly important where many PCR cycles are required, for e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31064-7
更新日期:2018-09-03 00:00:00
abstract::A generation of reactive oxygen species (ROS) from TiO2 under solar light has been long sought since the ROS can disinfect organic pollutants. We found that newly developed crystalline/amorphous reduced TiO2 (rTiO2) that has low energy bandgap can effectively generate ROS under solar light and successfully remove a bl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25212
更新日期:2016-04-28 00:00:00
abstract::Japan has often been viewed as an Asian country that possesses a genetically homogenous community. The basis for partitioning the country into prefectures has largely been geographical, although cultural and linguistic differences still exist between some of the districts/prefectures, especially between Okinawa and th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep17855
更新日期:2015-12-09 00:00:00
abstract::Bursaphelenchus xylophilus is a quarantined migratory endoparasite known to cause severe economic losses in pine forest ecosystems. The study presents the nematicidal effects of halogenated indoles on B. xylophilus and their action mechanisms. 5-Iodoindole and abamectin (positive control) at low concentration (10 µg/m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-07074-2
更新日期:2017-07-28 00:00:00
abstract::Decline in episodic memory performance usually causes the first clinical symptoms of Alzheimer's disease. At present, Alzheimer's disease can only be diagnosed at a very late stage when neurodegeneration and cognitive impairment is already irreversible. New early disease markers are needed for earlier and more efficie...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71239-9
更新日期:2020-08-25 00:00:00
abstract::Recruitment via settlement of pelagic larvae is critical for the persistence of benthic marine populations. For many benthic invertebrates, larval settlement occurs in response to surface microbial films. Larvae of the serpulid polychaete Hydroides elegans can be induced to settle by single bacterial species. Until no...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42557
更新日期:2017-02-14 00:00:00
abstract::The significant risk of disease transmission has selected for effective immune-defense strategies in insect societies. Division of labour, with individuals specialized in immunity-related tasks, strongly contributes to prevent the spread of diseases. A trade-off, however, may exist between phenotypic specialization to...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65780-w
更新日期:2020-06-02 00:00:00
abstract::The PDZ domain-containing scaffold protein, syntenin-1, binds to the transmembrane proteoglycan, syndecan-4, but the molecular mechanism/function of this interaction are unknown. Crystal structure analysis of syntenin-1/syndecan-4 cytoplasmic domains revealed that syntenin-1 forms a symmetrical pair of dimers anchored...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36818
更新日期:2016-11-10 00:00:00
abstract::Academic research on dinoflagellate, the primary causative agent of harmful algal blooms (HABs), is often hindered by the coexistence with bacteria in laboratory cultures. The development of axenic dinoflagellate cultures is challenging and no universally accepted method suit for different algal species. In this study...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80638-x
更新日期:2021-01-08 00:00:00
abstract::The knowledge of diffusion processes in semiconducting alloys is very important both technologically and from a theoretical point of view. Here we show that, self-diffusion in Si1-x Ge x alloys as a function of temperature and Ge concentration can be described by the cBΩ thermodynamic model. This model connects the ac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01301-6
更新日期:2017-05-02 00:00:00
abstract::A typical assumption made in the existing opinion formation models is that two individuals can communicate with each other only if the distance between their opinions is less than a threshold called bound of confidence. However, in the real world it is quite possible that people may also have a few friends with quite ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02968
更新日期:2013-10-17 00:00:00
abstract::Features from Electrovestibulography (EVestG) recordings have been used to classify and measure the severity of both persistent post-concussion syndrome (PCS) and major depressive disorder. Herein, we examined the effect of comorbid depression on the detection of persistent PCS using EVestG. To validate our previously...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/s41598-018-32808-1
更新日期:2018-09-27 00:00:00
abstract::Worldwide, Bartonella infections are known to inflict a wide range of mammals and, within rodents alone, more than 20 Bartonella species have been detected. There is, however, a lack of studies on the presence of Bartonella spp. in rodents in the Baltic region. We analysed 580 individuals belonging to eight small rode...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48715-y
更新日期:2019-08-26 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-42219-5
更新日期:2019-04-16 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-72921-8
更新日期:2020-09-24 00:00:00
abstract::The combination of navigation and robotics in spine surgery has the potential to accurately identify and maintain bone entry position and planned trajectory. The goal of this study was to examine the feasibility, accuracy and efficacy of a new robot-guided system for semi-automated, minimally invasive, pedicle screw p...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64462-x
更新日期:2020-05-05 00:00:00
abstract::Marine pollution is a significant issue in recent decades, with the increase in industries and their waste harming the environment and ecosystems. Notably, the rise in shellfish industries contributes to tons of shellfish waste composed of up to 58% chitin. Chitin, the second most ample polymer next to cellulose, is i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68772-y
更新日期:2020-07-17 00:00:00
abstract::The involvement of the immune system, particularly the role of T-cells, in sarcoidosis is unclear. The existence of higher CD4+ T-cells and increased CD4/CD8 ratio may indicate a pathogenic role of T-cells in the disease. In this study, we quantified the contribution of T-cells associated variants and of CD4/CD8 ratio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05754-7
更新日期:2017-07-17 00:00:00
abstract::Fluorescence-based western blots are quantitative in principal, but require determining linear range for each antibody. Here, we use microwestern array to rapidly evaluate suitable conditions for quantitative western blotting, with up to 192 antibody/dilution/replicate combinations on a single standard size gel with a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29436-0
更新日期:2018-07-27 00:00:00