The Combined Effect of Oseltamivir and Favipiravir on Influenza A Virus Evolution.

abstract：:Sex determination systems are exceptionally diverse and have undergone multiple and independent evolutionary transitions among species, particularly reptiles. However, the mechanisms underlying these transitions have not been established. Here, we tested for differences in sex-linked markers in the only known reptile ...

journal_title：Genome biology and evolution

authors： Hill PL,Burridge CP,Ezaz T,Wapstra E

更新日期：2018-04-01 00:00:00

abstract：:Bartonella is a genetically diverse group of vector-borne bacteria. Over 40 species have been characterized to date, mainly from mammalian reservoirs and arthropod vectors. Rodent reservoirs harbor one of the largest Bartonella diversity described to date, and novel species and genetic variants are continuously identi...

journal_title：Genome biology and evolution

authors： Gutiérrez R,Markus B,Carstens Marques de Sousa K,Marcos-Hadad E,Mugasimangalam RC,Nachum-Biala Y,Hawlena H,Covo S,Harrus S

更新日期：2018-11-01 00:00:00

abstract：:Gene duplication generates new genetic material, which has been shown to lead to major innovations in unicellular and multicellular organisms. A whole-genome duplication occurred in the ancestor of Saccharomyces yeast species but 92% of duplicates returned to single-copy genes shortly after duplication. The persisting...

journal_title：Genome biology and evolution

authors： Fares MA,Sabater-Muñoz B,Toft C

更新日期：2017-05-01 00:00:00

abstract：:Orphan genes are defined as genes that lack detectable similarity to genes in other species and therefore no clear signals of common descent (i.e., homology) can be inferred. Orphans are an enigmatic portion of the genome because their origin and function are mostly unknown and they typically make up 10% to 30% of all...

journal_title：Genome biology and evolution

authors： Wissler L,Gadau J,Simola DF,Helmkampf M,Bornberg-Bauer E

更新日期：2013-01-01 00:00:00

abstract：:Glycosaminoglycans are sulfated polysaccharide molecules, essential for many biological processes. The 6-O sulfation of glycosaminoglycans is carried out by carbohydrate 6-O sulfotransferases (C6OSTs), previously named Gal/GalNAc/GlcNAc 6-O sulfotransferases. Here, for the first time, we present a detailed phylogeneti...

journal_title：Genome biology and evolution

authors： Ocampo Daza D,Haitina T

更新日期：2020-07-01 00:00:00

abstract：:Immunity genes have repeatedly experienced natural selection during mammalian evolution. Galectins are carbohydrate-binding proteins that regulate diverse immune responses, including maternal-fetal immune tolerance in placental pregnancy. Seven human galectins, four conserved across vertebrates and three specific to p...

journal_title：Genome biology and evolution

authors： Ely ZA,Moon JM,Sliwoski GR,Sangha AK,Shen XX,Labella AL,Meiler J,Capra JA,Rokas A

更新日期：2019-09-01 00:00:00

abstract：:Cytoplasmic male sterility (MS) in plants is caused by MS-inducing mitochondria, which have emerged frequently during plant evolution. Nuclear restorer-of-fertility (Rf)genes can suppress their cognate MS-inducing mitochondria. Whereas many Rfs encode a class of RNA-binding protein, the sugar beet (Caryophyllales) Rf ...

journal_title：Genome biology and evolution

authors： Arakawa T,Kagami H,Katsuyama T,Kitazaki K,Kubo T

更新日期：2020-12-06 00:00:00

abstract：:Chaperonins promote protein folding and are known to play a role in the maintenance of cellular stability under stress conditions. The group I bacterial chaperonin complex comprises GroEL, that forms a barrel-like oligomer, and GroES that forms the lid. In most eubacteria the GroES/GroEL chaperonin is encoded by a sin...

journal_title：Genome biology and evolution

authors： Weissenbach J,Ilhan J,Bogumil D,Hülter N,Stucken K,Dagan T

更新日期：2017-01-01 00:00:00

abstract：:The predominantly aquatic order Alismatales, which includes approximately 4,500 species within Araceae, Tofieldiaceae, and the core alismatid families, is a key group in investigating the origin and early diversification of monocots. Despite their importance, phylogenetic ambiguity regarding the root of the Alismatale...

journal_title：Genome biology and evolution

authors： Luo Y,Ma PF,Li HT,Yang JB,Wang H,Li DZ

更新日期：2016-04-06 00:00:00

abstract：:By comparing the patterns of evolution in the coding and upstream noncoding regions of yeast ribosomal protein (RP) genes duplicated in a genome duplication, we find that although nonsynonymous sites in the coding sequences show strong evidence for the fixation of recent gene conversion events, similar patterns are le...

journal_title：Genome biology and evolution

authors： Evangelisti AM,Conant GC

更新日期：2010-01-01 00:00:00

abstract：:Explaining the evolution of animals requires ecological, developmental, paleontological, and phylogenetic considerations because organismal traits are affected by complex evolutionary processes. Modeling a plurality of processes, operating at distinct time-scales on potentially interdependent traits, can benefit from ...

journal_title：Genome biology and evolution

authors： Lord E,Pathmanathan JS,Corel E,Makarenkov V,Lopez P,Bouchard F,Bhattacharya D,Antoine PO,Le Guyader H,Lapointe FJ,Bapteste E

更新日期：2019-09-01 00:00:00

abstract：:Neotropical primates (NP) are presently distributed in the New World from Mexico to northern Argentina, comprising three large families, Cebidae, Atelidae, and Pitheciidae, consequently to their diversification following their separation from Old World anthropoids near the Eocene/Oligocene boundary, some 40 Ma. The ev...

journal_title：Genome biology and evolution

authors： Schrago CG,Menezes AN,Furtado C,Bonvicino CR,Seuanez HN

更新日期：2014-11-05 00:00:00

abstract：:Rieske/cytochrome b (Rieske/cytb) complexes are proton pumping quinol oxidases that are present in most bacteria and Archaea. The phylogeny of their subunits follows closely the 16S-rRNA phylogeny, indicating that chemiosmotic coupling was already present in the last universal common ancestor of Archaea and bacteria. ...

journal_title：Genome biology and evolution

authors： Baymann F,Schoepp-Cothenet B,Lebrun E,van Lis R,Nitschke W

更新日期：2012-01-01 00:00:00

abstract：:Horizontal gene transfer is a common mechanism in Bacteria that has contributed to the genomic content of existing organisms. Traditional methods for estimating bacterial phylogeny, however, assume only vertical inheritance in the evolution of homologous genes, which may result in errors in the estimated phylogenies. ...

journal_title：Genome biology and evolution

authors： Coimbra NDR,Goes-Neto A,Azevedo V,Ouangraoua A

更新日期：2020-04-01 00:00:00

abstract：:All living organisms require protein degradation to terminate biological processes and remove damaged proteins. One such machine is the 20S proteasome, a specialized barrel-shaped and compartmentalized multicatalytic protease. The activity of the 20S proteasome generally requires the binding of regulators/proteasome a...

journal_title：Genome biology and evolution

authors： Fort P,Kajava AV,Delsuc F,Coux O

更新日期：2015-05-04 00:00:00

abstract：:Tandem repeats (TRs) are highly dynamic regions of the genome. Mutations at these loci represent a significant source of genetic variation and can facilitate rapid adaptation. Bumblebees are important pollinating insects occupying a wide range of habitats. However, to date, molecular mechanisms underlying the potentia...

journal_title：Genome biology and evolution

authors： Zhao X,Su L,Schaack S,Sadd BM,Sun C

更新日期：2018-12-01 00:00:00

abstract：:Acquisition of Elizabethkingia infections in intensive care units (ICUs) has risen in the past decade. Treatment of Elizabethkingia infections is challenging due to the lack of effective therapeutic regimens, leading to a high mortality rate. Elizabethkingia infections have long been attributed to Elizabethkingia meni...

journal_title：Genome biology and evolution

authors： Teo J,Tan SY,Liu Y,Tay M,Ding Y,Li Y,Kjelleberg S,Givskov M,Lin RT,Yang L

更新日期：2014-05-06 00:00:00

abstract：:Recently, a new Chlamydia-related organism, Protochlamydia naegleriophila KNic, was discovered within a Naegleria amoeba. To decipher the mechanisms at play in the modeling of genomes from the Protochlamydia genus, we sequenced the full genome of Pr. naegleriophila, which includes a 2,885,090 bp chromosome and a 145,2...

journal_title：Genome biology and evolution

authors： Bertelli C,Cissé OH,Rusconi B,Kebbi-Beghdadi C,Croxatto A,Goesmann A,Collyn F,Greub G

更新日期：2016-08-25 00:00:00

abstract：:Nemerteans are one of few animal groups that have evolved the ability to utilize toxins for both defense and subduing prey, but little is known about specific nemertean toxins. In particular, no study has identified specific toxin genes even though peptide toxins are known from some nemertean species. Information abou...

journal_title：Genome biology and evolution

authors： Whelan NV,Kocot KM,Santos SR,Halanych KM

更新日期：2014-11-27 00:00:00

abstract：:RNA editing occurs in the organellar mRNAs of all land plants but the marchantioid liverworts, making liverworts a perfect group for studying the evolution of RNA editing. Here, we profiled the RNA editing of 42 exemplars spanning the ordinal phylogenetic diversity of liverworts, and screened for the nuclear-encoded p...

journal_title：Genome biology and evolution

authors： Dong S,Zhao C,Zhang S,Wu H,Mu W,Wei T,Li N,Wan T,Liu H,Cui J,Zhu R,Goffinet B,Liu Y

更新日期：2019-11-01 00:00:00

abstract：:Klebsiella pneumoniae clonal group (CG) 258, comprising sequence types (STs) 258, 11, and closely related variants, is associated with dissemination of the K. pneumoniae carbapenemase (KPC). Hospital outbreaks of KPC CG258 infections have been observed globally and are very difficult to treat. As a consequence, there ...

journal_title：Genome biology and evolution

authors： Wyres KL,Gorrie C,Edwards DJ,Wertheim HF,Hsu LY,Van Kinh N,Zadoks R,Baker S,Holt KE

更新日期：2015-04-10 00:00:00

abstract：:Gene duplication may be an important mechanism for the evolution of new functions and for the adaptive modulation of gene expression via dosage effects. Here, we analyzed the fate of gene duplicates for two strains of a novel group of cyanobacteria (genus Acaryochloris) that produces the far-red light absorbing chloro...

journal_title：Genome biology and evolution

authors： Miller SR,Wood AM,Blankenship RE,Kim M,Ferriera S

更新日期：2011-01-01 00:00:00

abstract：:Transposable elements (TEs) constitute a substantial portion of many eukaryotic genomes, and can in principle contribute to evolutionary innovation as well as genomic deterioration. Daphnia pulex serves as a useful model for studying TE dynamics as a potential cause and/or consequence of asexuality. We analyzed insert...

journal_title：Genome biology and evolution

authors： Jiang X,Tang H,Ye Z,Lynch M

更新日期：2017-02-01 00:00:00

abstract：:Olfactory receptors (ORs) are membrane proteins that mediate the detection of odorants in the environment, and are the largest vertebrate gene family. Comparative studies of mammalian genomes indicate that OR repertoires vary widely, even between closely related lineages, as a consequence of frequent OR gains and loss...

journal_title：Genome biology and evolution

authors： Vandewege MW,Mangum SF,Gabaldón T,Castoe TA,Ray DA,Hoffmann FG

更新日期：2016-02-09 00:00:00

abstract：:The root-knot nematodes (genus Meloidogyne) are important plant parasites causing substantial agricultural losses. The Meloidogyne incognita group (MIG) of species, most of which are obligatory apomicts (mitotic parthenogens), are extremely polyphagous and important problems for global agriculture. While understanding...

journal_title：Genome biology and evolution

authors： Szitenberg A,Salazar-Jaramillo L,Blok VC,Laetsch DR,Joseph S,Williamson VM,Blaxter ML,Lunt DH

更新日期：2017-10-01 00:00:00

abstract：:The main genomic changes in the evolution of host-restricted microbial symbionts are ongoing inactivation and loss of genes combined with rapid sequence evolution and extreme structural stability; these changes reflect high levels of genetic drift due to small population sizes and strict clonality. This genomic erosio...

journal_title：Genome biology and evolution

authors： McCutcheon JP,Moran NA

更新日期：2010-01-01 00:00:00

abstract：:The process of transcription is highly stochastic leading to cell-to-cell variations and noise in gene expression levels. However, key essential genes have to be precisely expressed at the correct amount and time to ensure proper cellular development and function. Studies in yeast and bacterial systems have shown that...

journal_title：Genome biology and evolution

authors： Vance KW,Woodcock DJ,Reid JE,Bretschneider T,Ott S,Koentges G

更新日期：2015-09-04 00:00:00

abstract：:The identification of conserved syntenic regions enables discovery of predicted locations for orthologous and homeologous genes, even when no such gene is present. This capability means that synteny-based methods are far more effective than sequence similarity-based methods in identifying true-negatives, a necessity f...

journal_title：Genome biology and evolution

authors： Tang H,Bomhoff MD,Briones E,Zhang L,Schnable JC,Lyons E

更新日期：2015-11-11 00:00:00

abstract：:Retrotransposons, DNA sequences capable of creating copies of themselves, compose about half of the human genome and played a central role in the evolution of mammals. Their current position in the host genome is the result of the retrotranscription process and of the following host genome evolution. We apply a model ...

journal_title：Genome biology and evolution

authors： Riba A,Fumagalli MR,Caselle M,Osella M

更新日期：2020-11-03 00:00:00

abstract：:The globin gene family encodes oxygen-binding hemeproteins conserved across the major branches of multicellular life. The origins and evolutionary histories of complete globin repertoires have been established for many vertebrates, but there remain major knowledge gaps for ray-finned fish. Therefore, we used phylogene...

journal_title：Genome biology and evolution

authors： Gallagher MD,Macqueen DJ

更新日期：2017-01-01 00:00:00