Genome Mutational and Transcriptional Hotspots Are Traps for Duplicated Genes and Sources of Adaptations.

abstract：:Thousands of candidate human-specific regulatory sequences (HSRS) have been identified, supporting the hypothesis that unique to human phenotypes result from human-specific alterations of genomic regulatory networks. Collectively, a compendium of multiple diverse families of HSRS that are functionally and structurally...

journal_title：Genome biology and evolution

authors： Glinsky GV

更新日期：2016-09-19 00:00:00

abstract：:piRNA clusters are thought to repress transposable element (TE) activity in mammals and invertebrates. Here, we show that a simple population genetics model reveals a constraint on the size of piRNA clusters: The total size of the piRNA clusters of an organism must exceed 0.2% of a genome to repress TE invasions. More...

journal_title：Genome biology and evolution

authors： Kofler R

更新日期：2020-05-01 00:00:00

abstract：:Whole-genome duplications are radical evolutionary events that have driven speciation and adaptation in many taxa. Higher-order polyploids have complex histories often including interspecific hybridization and dynamic genomic changes. This chromosomal reshuffling is poorly understood for most polyploid species, despit...

journal_title：Genome biology and evolution

authors： Tennessen JA,Govindarajulu R,Ashman TL,Liston A

更新日期：2014-12-04 00:00:00

abstract：:Organisms show striking differences in genome structure; however, the functional implications and fundamental forces that govern these differences remain obscure. The intron-exon organization of nuclear genes is involved in a particularly large variety of structures and functional roles. We performed a 22-species stud...

journal_title：Genome biology and evolution

authors： Irimia M,Maeso I,Burguera D,Hidalgo-Sánchez M,Puelles L,Roy SW,Garcia-Fernàndez J,Ferran JL

更新日期：2011-01-01 00:00:00

abstract：:Allopolyploidization plays an important role in speciation, and some natural or synthetic allopolyploid fishes have been extensively applied to aquaculture. Although genetic and epigenetic inheritance and variation associated with plant allopolyploids have been well documented, the relative research in allopolyploid a...

journal_title：Genome biology and evolution

authors： Shao GM,Li XY,Wang Y,Wang ZW,Li Z,Zhang XJ,Zhou L,Gui JF

更新日期：2018-09-01 00:00:00

abstract：:The extent of genome divergence and the evolutionary events leading to speciation of marine bacteria have mostly been studied for (locally) abundant, free-living groups. The genus Phaeobacter is found on different marine surfaces, seems to occupy geographically disjunct habitats, and is involved in different biotic in...

journal_title：Genome biology and evolution

authors： Freese HM,Sikorski J,Bunk B,Scheuner C,Meier-Kolthoff JP,Spröer C,Gram L,Overmann J

更新日期：2017-12-01 00:00:00

abstract：:Klebsiella pneumoniae clonal group (CG) 258, comprising sequence types (STs) 258, 11, and closely related variants, is associated with dissemination of the K. pneumoniae carbapenemase (KPC). Hospital outbreaks of KPC CG258 infections have been observed globally and are very difficult to treat. As a consequence, there ...

journal_title：Genome biology and evolution

authors： Wyres KL,Gorrie C,Edwards DJ,Wertheim HF,Hsu LY,Van Kinh N,Zadoks R,Baker S,Holt KE

更新日期：2015-04-10 00:00:00

abstract：:Taeniid cestodes (including the human parasites Echinococcus spp. and Taenia solium) have very few mobile genetic elements (MGEs) in their genome, despite lacking a canonical PIWI pathway. The MGEs of these parasites are virtually unexplored, and nothing is known about their expression and silencing. In this work, we ...

journal_title：Genome biology and evolution

authors： Koziol U,Radio S,Smircich P,Zarowiecki M,Fernández C,Brehm K

更新日期：2015-07-01 00:00:00

abstract：:Bacteria of the genus Xenorhabdus are symbionts of soil entomopathogenic nematodes of the genus Steinernema. This symbiotic association constitutes an insecticidal complex active against a wide range of insect pests. Unlike other Xenorhabdus species, Xenorhabdus poinarii is avirulent when injected into insects in the ...

journal_title：Genome biology and evolution

authors： Ogier JC,Pagès S,Bisch G,Chiapello H,Médigue C,Rouy Z,Teyssier C,Vincent S,Tailliez P,Givaudan A,Gaudriault S

更新日期：2014-06-05 00:00:00

abstract：:The evolution of a mechanically resilient epidermis was a key adaptation in the transition of amniotes to a fully terrestrial lifestyle. Skin appendages usually form via a specialized type of programmed cell death known as cornification which is characterized by the formation of an insoluble cornified envelope (CE). M...

journal_title：Genome biology and evolution

authors： Davis AC,Greenwold MJ,Sawyer RH

更新日期：2019-03-01 00:00:00

abstract：:Macroevolutionary trends exhibited by retroviruses are complex and not entirely understood. The sloth endogenized foamy-like retrovirus (SloEFV), which demonstrates incongruence in virus-host evolution among extant sloths (Order Folivora), has not been investigated heretofore in any extinct sloth lineages and its prem...

journal_title：Genome biology and evolution

authors： Slater GJ,Cui P,Forasiepi AM,Lenz D,Tsangaras K,Voirin B,de Moraes-Barros N,MacPhee RD,Greenwood AD

更新日期：2016-02-14 00:00:00

abstract：:The presence of spliceosomal introns in eukaryotic genes poses a major puzzle for the study of genome evolution. Intron densities vary enormously among distant lineages. However, the mechanisms driving intron gains are poorly understood and very few intron gains and losses have been documented over short evolutionary ...

journal_title：Genome biology and evolution

authors： Croll D,McDonald BA

更新日期：2012-01-01 00:00:00

abstract：:Clashes between transcription and replication complexes can cause point mutations and chromosome rearrangements on heavily transcribed genes. In eukaryotic ribosomal RNA genes, the system that prevents transcription-replication conflicts also causes frequent copy number variation. Such fast mutational dynamics do not ...

journal_title：Genome biology and evolution

authors： Colizzi ES,Hogeweg P

更新日期：2019-11-01 00:00:00

abstract：:Rieske/cytochrome b (Rieske/cytb) complexes are proton pumping quinol oxidases that are present in most bacteria and Archaea. The phylogeny of their subunits follows closely the 16S-rRNA phylogeny, indicating that chemiosmotic coupling was already present in the last universal common ancestor of Archaea and bacteria. ...

journal_title：Genome biology and evolution

authors： Baymann F,Schoepp-Cothenet B,Lebrun E,van Lis R,Nitschke W

更新日期：2012-01-01 00:00:00

abstract：:Dosage compensation--equalizing gene expression levels in response to differences in gene dose or copy number--is classically considered to play a critical role in the evolution of heteromorphic sex chromosomes. As the X and Y diverge through degradation and gene loss on the Y (or the W in female-heterogametic ZW taxa...

journal_title：Genome biology and evolution

authors： Walters JR,Hardcastle TJ

更新日期：2011-01-01 00:00:00

abstract：:Colonization of new habitats often reduces population sizes and may result in the accumulation of deleterious mutations by genetic drift. Compared with the genomic basis for adaptation to new environments, genome-wide analysis of deleterious mutations in isolated populations remains limited. In the present study, we i...

journal_title：Genome biology and evolution

authors： Yoshida K,Ravinet M,Makino T,Toyoda A,Kokita T,Mori S,Kitano J

更新日期：2020-04-01 00:00:00

abstract：:Dinoflagellates are a group of unicellular protists with immense ecological and evolutionary significance and cell biological diversity. Of the photosynthetic dinoflagellates, the majority possess a plastid containing the pigment peridinin, whereas some lineages have replaced this plastid by serial endosymbiosis with ...

journal_title：Genome biology and evolution

authors： Klinger CM,Paoli L,Newby RJ,Wang MY,Carroll HD,Leblond JD,Howe CJ,Dacks JB,Bowler C,Cahoon AB,Dorrell RG,Richardson E

更新日期：2018-04-01 00:00:00

abstract：:Prokaryote genomes are the result of a dynamic flux of genes, with increases achieved via horizontal gene transfer and reductions occurring through gene loss. The ecological and selective forces that drive this genomic flexibility vary across species. Bacillus subtilis is a naturally competent bacterium that occupies ...

journal_title：Genome biology and evolution

authors： Brito PH,Chevreux B,Serra CR,Schyns G,Henriques AO,Pereira-Leal JB

更新日期：2018-01-01 00:00:00

abstract：:Different genes and proteins evolve at very different rates. To identify the factors that explain these differences is an important aspect of research in molecular evolution. One such factor is the role a protein plays in a large molecular network. Here, we analyze the evolutionary rates of enzyme-coding genes in the ...

journal_title：Genome biology and evolution

authors： Aguilar-Rodríguez J,Wagner A

更新日期：2018-11-01 00:00:00

abstract：:Many organisms have a global mechanism for dosage compensation (DC) operating along the entire male X chromosome, which equalizes gene expression on the male X with that on the two Xs in females and/or on autosomes. At the initial stage of sex chromosome evolution, however, gene-by-gene (or localized) DC may also be n...

journal_title：Genome biology and evolution

authors： Nozawa M,Ikeo K,Gojobori T

更新日期：2018-08-01 00:00:00

abstract：:The Bateson-Dobzhansky-Muller (BDM) model of reproductive isolation by genetic incompatibility is a widely accepted model of speciation. Because of the exceptionally rich biological information about the budding yeast Saccharomyces cerevisiae, the identification of BDM incompatibilities in yeast would greatly deepen o...

journal_title：Genome biology and evolution

authors： Li C,Wang Z,Zhang J

更新日期：2013-01-01 00:00:00

abstract：:Most land plant plastomes contain two copies of a large inverted repeat (IR) that promote high-frequency homologous recombination to generate isomeric genomic forms. Among conifer plastomes, this canonical IR is highly reduced in Pinaceae and completely lost from cupressophytes. However, both lineages have acquired sh...

journal_title：Genome biology and evolution

authors： Guo W,Grewe F,Cobo-Clark A,Fan W,Duan Z,Adams RP,Schwarzbach AE,Mower JP

更新日期：2014-03-01 00:00:00

abstract：:MicroRNAs (miRNAs) are short endogenous RNA molecules that regulate gene expression at the posttranscriptional level and have been shown to play critical roles during animal development. The identification and comparison of miRNAs in metazoan species are therefore paramount for our understanding of the evolution of bo...

journal_title：Genome biology and evolution

authors： Marco A,Hui JH,Ronshaugen M,Griffiths-Jones S

更新日期：2010-01-01 00:00:00

abstract：:Immunity genes have repeatedly experienced natural selection during mammalian evolution. Galectins are carbohydrate-binding proteins that regulate diverse immune responses, including maternal-fetal immune tolerance in placental pregnancy. Seven human galectins, four conserved across vertebrates and three specific to p...

journal_title：Genome biology and evolution

authors： Ely ZA,Moon JM,Sliwoski GR,Sangha AK,Shen XX,Labella AL,Meiler J,Capra JA,Rokas A

更新日期：2019-09-01 00:00:00

abstract：:Evolution of prokaryotes involves extensive loss and gain of genes, which lead to substantial differences in the gene repertoires even among closely related organisms. Through a wide range of phylogenetic depths, gene frequency distributions in prokaryotic pangenomes bear a characteristic, asymmetrical U-shape, with a...

journal_title：Genome biology and evolution

authors： Lobkovsky AE,Wolf YI,Koonin EV

更新日期：2013-01-01 00:00:00

abstract：:The large repABC plasmids of the order Rhizobiales with Class I quorum-regulated conjugative transfer systems often define the nature of the bacterium that harbors them. These otherwise diverse plasmids contain a core of highly conserved genes for replication and conjugation raising the question of their evolutionary ...

journal_title：Genome biology and evolution

authors： Wetzel ME,Olsen GJ,Chakravartty V,Farrand SK

更新日期：2015-11-19 00:00:00

abstract：:The plastid genomes of four related carnivorous plants (Drosera regia, Drosera erythrorhiza, Aldrovanda vesiculosa, and Dionaea muscipula) were sequenced to examine changes potentially induced by the transition to carnivory. The plastid genomes of the Droseraceae show multiple rearrangements, gene losses, and large ex...

journal_title：Genome biology and evolution

authors： Nevill PG,Howell KA,Cross AT,Williams AV,Zhong X,Tonti-Filippini J,Boykin LM,Dixon KW,Small I

更新日期：2019-02-01 00:00:00

abstract：:Lycopodiophyta-consisting of three orders, Lycopodiales, Isoetales and Selaginellales, with different types of shoot apical meristems (SAMs)-form the earliest branch among the extant vascular plants. They represent a sister group to all other vascular plants, from which they differ in that their leaves are microphylls...

journal_title：Genome biology and evolution

authors： Evkaikina AI,Berke L,Romanova MA,Proux-Wéra E,Ivanova AN,Rydin C,Pawlowski K,Voitsekhovskaja OV

更新日期：2017-09-01 00:00:00

abstract：:Gene duplications and novel genes have been shown to play a major role in helminth adaptation to a parasitic lifestyle because they provide the novelty necessary for adaptation to a changing environment, such as living in multiple hosts. Here we present the de novo sequenced and annotated genome of the parasitic trema...

journal_title：Genome biology and evolution

authors： Zajac N,Zoller S,Seppälä K,Moi D,Dessimoz C,Jokela J,Hartikainen H,Glover N

更新日期：2021-01-23 00:00:00

abstract：:We previously discovered that lagging strand genes evolve faster in Bacillus subtilis (and potentially other bacteria). Lagging strand genes are transcribed in the head-on orientation with respect to DNA replication, leading to collisions between the two machineries that stall replication and can destabilize genomes. ...

journal_title：Genome biology and evolution

authors： Merrikh CN,Weiss E,Merrikh H

更新日期：2016-12-01 00:00:00