Corrigendum: Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles.

abstract：:Selective inhibition of function-specific β-GlcNAcase has great potential in terms of drug design and biological research. The symmetrical bis-naphthalimide M-31850 was previously obtained by screening for specificity against human glycoconjugate-lytic β-GlcNAcase. Using protein-ligand co-crystallization and molecular...

journal_title：Scientific reports

authors： Liu T,Guo P,Zhou Y,Wang J,Chen L,Yang H,Qian X,Yang Q

更新日期：2014-08-26 00:00:00

abstract：:We demonstrated tailored plasmon-induced transparency (PIT) in a metal (Au)-insulator (SiO2)-metal (Ag) (MIM) structure, where the Fano interference between the MIM waveguide mode and the surface plasmon polariton (SPP) resonance mode induced a transparency window in an otherwise opaque wavenumber (k) region. A series...

journal_title：Scientific reports

authors： Matsunaga K,Hirai Y,Neo Y,Matsumoto T,Tomita M

更新日期：2017-12-19 00:00:00

abstract：:Antidiabetic medication may modify the incidence of hepatocellular carcinoma (HCC). We aimed to compare the use of different antidiabetic strategies and the incidence of HCC. PubMed, Embase.com and Cochrane Library databases were searched up to 31 October 2015 and randomized controlled trials (RCTs), cohort studies or...

journal_title：Scientific reports

authors： Zhou YY,Zhu GQ,Liu T,Zheng JN,Cheng Z,Zou TT,Braddock M,Fu SW,Zheng MH

更新日期：2016-09-19 00:00:00

abstract：:Juvenile hormone (JH) plays crucial roles in many aspects of the insect life. All the JH actions are initiated by transport of JH in the hemolymph as a complex with JH-binding protein (JHBP) to target tissues. Here, we report structural mechanism of JH delivery by JHBP based upon the crystal and solution structures of...

journal_title：Scientific reports

authors： Suzuki R,Fujimoto Z,Shiotsuki T,Tsuchiya W,Momma M,Tase A,Miyazawa M,Yamazaki T

更新日期：2011-01-01 00:00:00

abstract：:Continuous solidification experiments were carried out with Cu-Bi-Sn alloys under the effects of Electric Current Pulses (ECPs). A model describing the microstructure evolution was developed. The formation of the microstructure in the continuously solidified alloys was calculated. The calculations demonstrated that EC...

journal_title：Scientific reports

authors： Hongxiang J,Jie H,Jiuzhou Z

更新日期：2015-07-31 00:00:00

abstract：:Unimolecular dual agonists for the glucagon-like peptide 1 receptor (GLP1R) and glucagon receptor (GCGR) are emerging as a potential new class of important therapeutics in type 2 diabetes (T2D). Reliable and quantitative assessments of in vivo occupancy on each receptor would improve the understanding of the efficacy ...

journal_title：Scientific reports

authors： Eriksson O,Haack T,Hijazi Y,Teichert L,Tavernier V,Laitinen I,Berglund JE,Antoni G,Velikyan I,Johansson L,Pierrou S,Wagner M,Tillner J

更新日期：2020-10-07 00:00:00

abstract：:Recent work reveals that the extinction of conditioned fear depends upon the interval between conditioning and extinction. Extinction training that takes place within minutes to hours after fear conditioning fails to produce a long-term extinction memory, a phenomenon known as the immediate extinction deficit (IED). N...

journal_title：Scientific reports

authors： Totty MS,Payne MR,Maren S

更新日期：2019-07-01 00:00:00

abstract：:Energetic ions have been widely used to evaluate the irradiation tolerance of structural materials for nuclear power applications and to modify material properties. It is important to understand the defect production, annihilation and migration mechanisms during and after collision cascades. In this study, single crys...

journal_title：Scientific reports

authors： Lu C,Jin K,Béland LK,Zhang F,Yang T,Qiao L,Zhang Y,Bei H,Christen HM,Stoller RE,Wang L

更新日期：2016-02-01 00:00:00

abstract：:Understanding the drivers of animal movement is significant for ecology and biology. Yet researchers have so far been unable to fully understand these drivers, largely due to low data resolution. In this study, we analyse a high-frequency movement dataset for a group of grazing cattle and investigate their spatiotempo...

journal_title：Scientific reports

authors： Zhao K,Jurdak R

更新日期：2016-08-24 00:00:00

abstract：:Although electroporation has been widely accepted as the main gene transfer tool, there is still considerable scope to improve the electroporation efficiency of exogenous DNAs into primary cells. Here, we developed a square-wave pulsing protocol using OptiMEM-GlutaMAX for highly efficient transfection of murine embryo...

journal_title：Scientific reports

authors： Eghbalsaied S,Hyder I,Kues WA

更新日期：2020-08-07 00:00:00

abstract：:To demonstrate the identification of corneal diseases using a novel deep learning algorithm. A novel hierarchical deep learning network, which is composed of a family of multi-task multi-label learning classifiers representing different levels of eye diseases derived from a predefined hierarchical eye disease taxonomy...

journal_title：Scientific reports

authors： Gu H,Guo Y,Gu L,Wei A,Xie S,Ye Z,Xu J,Zhou X,Lu Y,Liu X,Hong J

更新日期：2020-10-20 00:00:00

abstract：:Insects harbor a wide variety of microorganisms that form complex and changing communities and play an important role in the biology and evolution of their hosts. Aphids have been used as model organisms to study microorganism-insect interactions. Almost all aphids are infected with the obligate endosymbiont Buchnera ...

journal_title：Scientific reports

authors： Gallo-Franco JJ,Duque-Gamboa DN,Toro-Perea N

更新日期：2019-04-08 00:00:00

abstract：:We investigated a high-quality MgB2 thin film with a thickness of ~1000 nm on an Al2O3 substrate using optical spectroscopy. We measured the reflectance spectra of the film at various temperatures both below, and above, the superconducting transition temperature, T c   [Formula: see text] 40 K. An earlier study showed...

journal_title：Scientific reports

authors： Seo YS,Lee JH,Kang WN,Hwang J

更新日期：2017-08-21 00:00:00

abstract：:Mechanistic studies of deregulated ERG in prostate cancer and other cancers continue to enhance its role in cancer biology and its utility as a biomarker and therapeutic target. Here, we show that ERG, through its physical interaction with androgen receptor, induces AR aggregation and endoplasmic reticulum stress in t...

journal_title：Scientific reports

authors： Sreenath TL,Macalindong SS,Mikhalkevich N,Sharad S,Mohamed A,Young D,Borbiev T,Xavier C,Gupta R,Jamal M,Babcock K,Tan SH,Nevalainen MT,Dobi A,Petrovics G,Sesterhenn IA,Rosner IL,Bieberich CJ,Nelson P,Vasioukhin V,

更新日期：2017-04-24 00:00:00

abstract：:The ubiquitin-proteasomal degradation mechanism has gained the attention over the past decade. The E2 ubiquitin conjugating enzymes are the crucial part of ubiquitination mechanism and they are believed to hold imperative association for plant development. It accepts ubiquitin from the E1 enzyme and interacts with the...

journal_title：Scientific reports

authors： Sharma B,Bhatt TK

更新日期：2017-08-17 00:00:00

abstract：:Current literature suggests that epigenetically regulated super-enhancers (SEs) are drivers of aberrant gene expression in cancers. Many tumor types are still missing chromatin data to define cancer-specific SEs and their role in carcinogenesis. In this work, we develop a simple pipeline, which can utilize chromatin d...

journal_title：Scientific reports

authors： Flam EL,Danilova L,Kelley DZ,Stavrovskaya E,Guo T,Considine M,Qian J,Califano JA,Favorov A,Fertig EJ,Gaykalova DA

更新日期：2019-10-21 00:00:00

abstract：:To investigate the concentrations of rare earth elements in cereals and assess human health risk through cereal consumption, a total of 327 cereal samples were collected from rare earth mining area and control area in Shandong, China. The contents of 14 rare earth elements were determined by Inductively Coupled Plasma...

journal_title：Scientific reports

authors： Zhuang M,Wang L,Wu G,Wang K,Jiang X,Liu T,Xiao P,Yu L,Jiang Y,Song J,Zhang J,Zhou J,Zhao J,Chu Z

更新日期：2017-08-29 00:00:00

abstract：:Deformable elastomeric spheres are evaluated experimentally as they skip multiple times over a lake surface. Some spheres are embedded with small inertial measurement units to measure the acceleration experienced during water surface impact. A model for multiple impact events shows good agreement between measured acce...

journal_title：Scientific reports

authors： Hurd RC,Belden J,Bower AF,Holekamp S,Jandron MA,Truscott TT

更新日期：2019-04-15 00:00:00

abstract：:Lipid lateral diffusion in membrane bilayers is a fundamental process exploited by cells to enable complex protein structural and dynamic reorganizations. For its importance, lipid mobility in both cellular and model bilayers has been extensively investigated in recent years, especially through the application of time...

journal_title：Scientific reports

authors： Jan Akhunzada M,D'Autilia F,Chandramouli B,Bhattacharjee N,Catte A,Di Rienzo R,Cardarelli F,Brancato G

更新日期：2019-02-06 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is an important risk factor for the development of type 2 diabetes mellitus. Interferon gamma-induced protein 10 (IP-10), a proinflammatory chemokine, plays a crucial role in inflammatory diseases. This cross-sectional pilot study investigated whether circulating IP-10 is assoc...

journal_title：Scientific reports

authors： Chang CC,Wu CL,Su WW,Shih KL,Tarng DC,Chou CT,Chen TY,Kor CT,Wu HM

更新日期：2015-05-11 00:00:00

abstract：:Complex Semi-Definite Programming (SDP) is introduced as a novel approach to phase retrieval enabled control of monochromatic light transmission through highly scattering media. In a simple optical setup, a spatial light modulator is used to generate a random sequence of phase-modulated wavefronts, and the resulting i...

journal_title：Scientific reports

authors： N'Gom M,Lien MB,Estakhri NM,Norris TB,Michielssen E,Nadakuditi RR

更新日期：2017-05-31 00:00:00

abstract：:Estradiol derived from neural aromatization of testosterone plays a key role in the organization and activation of neural structures underlying male behaviors. This study evaluated the contribution of the estrogen receptor (ER) β in estradiol-induced modulation of social and mood-related behaviors by using mice lackin...

journal_title：Scientific reports

authors： Dombret C,Naulé L,Trouillet AC,Parmentier C,Hardin-Pouzet H,Mhaouty-Kodja S

更新日期：2020-04-10 00:00:00

abstract：:Defense mechanisms of plant genomes can epigenetically inactivate repetitive sequences and exogenous transgenes. Loss of mutant phenotypes in intronic T-DNA insertion lines by interaction with another T-DNA locus, termed T-DNA suppression, has been observed in Arabidopsis thaliana, although the molecular basis of esta...

journal_title：Scientific reports

authors： Osabe K,Harukawa Y,Miura S,Saze H

更新日期：2017-03-24 00:00:00

abstract：:Kinkarakawa-gami wallpapers are unique works of art produced in Japan between 1870 and 1905 and exported in European countries, although only few examples are nowadays present in Europe. So far, neither the wallpapers nor the composing materials have been characterised, limiting the effective conservation-restoration ...

journal_title：Scientific reports

authors： Piacenza E,Presentato A,Di Salvo F,Alduina R,Ferrara V,Minore V,Giannusa A,Sancataldo G,Chillura Martino DF

更新日期：2020-10-02 00:00:00

abstract：:This study aimed to explore the effects of radiochemotherapy on the neurocognitive function of patients with high-grade gliomas (HGG). The mini-mental state examination (MMSE), Montreal Cognitive Assessment (MoCA), event-related potential P300 (ERP-P300), and specific MRI parameters were compared, and the associations...

journal_title：Scientific reports

authors： Bian Y,Meng L,Peng J,Li J,Wei R,Huo L,Yang H,Wang Y,Fu J,Shen L,Hong J

更新日期：2019-04-12 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is an EBV-associated epithelial malignancy prevalent in southern China. Presence of treatment-resistant cancer stem cells (CSC) may associate with tumor relapse and metastasis in NPC. ICG-001 is a specific CBP/β-catenin antagonist that can block CBP/β-catenin-mediated transcription of st...

journal_title：Scientific reports

authors： Chan KC,Chan LS,Ip JC,Lo C,Yip TT,Ngan RK,Wong RN,Lo KW,Ng WT,Lee AW,Tsao GS,Kahn M,Lung ML,Mak NK

更新日期：2015-04-21 00:00:00

abstract：:Appropriate isolation methods are essential for unravelling the relative contribution of extracellular vesicles (EVs) and the EV-free secretome to homeostasis and disease. We hypothesized that ultrafiltration followed by size exclusion chromatography (UF-SEC) provides well-matched concentrates of EVs and free secreted...

journal_title：Scientific reports

authors： Benedikter BJ,Bouwman FG,Vajen T,Heinzmann ACA,Grauls G,Mariman EC,Wouters EFM,Savelkoul PH,Lopez-Iglesias C,Koenen RR,Rohde GGU,Stassen FRM

更新日期：2017-11-10 00:00:00

abstract：:Nuclear receptor corepressor 1 (NCOR1) is a transcriptional regulator bridging repressive chromatin modifying enzymes with transcription factors. NCOR1 regulates many biological processes, however its role in T cells is not known. Here we show that Cd4-Cre-mediated deletion of NCOR1 (NCOR1 cKOCd4) resulted in a reduct...

journal_title：Scientific reports

authors： Müller L,Hainberger D,Stolz V,Hamminger P,Hassan H,Preglej T,Boucheron N,Sakaguchi S,Wiegers GJ,Villunger A,Auwerx J,Ellmeier W

更新日期：2017-11-21 00:00:00

abstract：:On-chip integration of optical detection units into the microfluidic systems for online monitoring is highly desirable for many applications and is also well in line with the spirit of optofluidics technology-fusion of optics and microfluidics for advanced functionalities. This paper reports the construction of a UV-V...

journal_title：Scientific reports

authors： Wang N,Tan F,Zhao Y,Tsoi CC,Fan X,Yu W,Zhang X

更新日期：2016-06-29 00:00:00

abstract：:In this work, we propose the concept to use the hydrophilic or neutral surface for condensation heat transfer and to use the superhydrophobic surface for enhancement by self-shedding and sweeping of condensate. Molecular dynamics simulation results show that no matter the vapor condenses on the solid surface in dropwi...

journal_title：Scientific reports

authors： Sun J,Wang HS

更新日期：2017-08-17 00:00:00