Abstract:
:The chitosan based on purified regeneration could be dissolved in 6wt% aqueous NaOH without freeze-thawing cycles and acetylation processing, and such a solution system was effective and different from other dissolving methods Upon heating, a tough hydrogel was constructed from the chitosan (purified regeneration) alkaline solution. The results of XRD, TEM, SEM and rheology analysis proved that chitosan easily aggregated in the solution and formed a nanofibers network to gelate at elevated temperature and concentration. The merely chitosan hydrogel had a uniform network structure and its (5wt%) compressive fracture stress could reach 0.2MPa. Furthermore, the hydrogels exhibited excellent biodegradability, blood compatibility and cellular compatibility. Therefore, the tough chitosan hydrogels may have a wide range of applications in biomedicine.
journal_name
Int J Biol Macromoljournal_title
International journal of biological macromoleculesauthors
Bi S,Bao Z,Bai X,Hu S,Cheng X,Chen Xdoi
10.1016/j.ijbiomac.2017.06.017subject
Has Abstractpub_date
2017-11-01 00:00:00pages
224-231issue
Pt Aeissn
0141-8130issn
1879-0003pii
S0141-8130(16)32764-7journal_volume
104pub_type
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