Type 2 diabetes alters hippocampal gamma oscillations: A potential mechanism behind impaired cognition.

Abstract:

:Type 2 diabetes (T2D) has been associated with cognitive decline, dementia and Alzheimer's disease (AD). Remarkably, the pathophysiological mechanisms behind this are still mostly unknown. Cognition and memory formation are associated with gamma oscillations in hippocampal neuronal networks and fast-spiking, parvalbumin-expressing interneurons (PV+ IN) play a key role in these processes.

journal_title

Psychoneuroendocrinology

authors

Lietzau G,Darsalia V,Pintana H,Östenson CG,Nyström T,Fisahn A,Patrone C

doi

10.1016/j.psyneuen.2017.04.012

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

46-50

eissn

0306-4530

issn

1873-3360

pii

S0306-4530(17)30181-6

journal_volume

82

pub_type

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