Abstract:
Objectives:To evaluate pediatric intensive care unit (PICU) needs, outcome and predictors of mortality in post-neonatal tetanus. Materials and methods:Review of 30 consecutive post-neonatal tetanus cases aged 1 months to 12 years admitted to a PICU in north India over a period of 10 years (January 2006 to December 2015). Results:Chronic suppurative otitis media was the commonest portal of entry. All received tetanus toxoid, human tetanus immunoglobulin (HTIG) and appropriate antibiotics; 7 (23.3%) received intrathecal HTIG. Common complications were respiratory failure, rhabdomyolysis, autonomic dysfunction, acute kidney injury and healthcare-associated infections. PICU needs were as follows: ventilation; benzodiazepine, morphine and magnesium sulfate infusion; neuromuscular blockers, inotropes, tracheostomy and renal replacement therapy. Mortality rate was 40%; severity Grade IIIb, autonomic dysfunction, use of vasoactive drugs and those who did not receive intrathecal HTIG were significantly associated with mortality. Conclusion:Post-neonatal tetanus is associated with high mortality, and PICU needs include management of spasms, autonomic dysfunction and complications and cardiorespiratory support.
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
Angurana SK,Jayashree M,Bansal A,Singhi S,Nallasamy Kdoi
10.1093/tropej/fmx020subject
Has Abstractpub_date
2018-02-01 00:00:00pages
15-23issue
1eissn
0142-6338issn
1465-3664pii
3778349journal_volume
64pub_type
杂志文章abstract:BACKGROUND:Results in neonatal screening programs aiming at detection of congenital adrenal hyperplasia (CAH) can only report elevated levels of 17-hydroxy-progesterone (17-OHP), without being able to differentiate presence or absence of salt loss. AIM:To predict presence or absence of salt loss in newborn infants wit...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00
abstract::The aim of the study was to explore the relationship between protein nutritional status and the development of rickets in children living in northern Nigeria. The diagnosis of rickets in 16 children between the ages of 10 months and 7 years was confirmed using established, and recently developed clinical and biochemic...
journal_title:Journal of tropical pediatrics
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abstract::A review of case histories of mother-infant pairs who attended a lactation clinic between January and December, 1989 is presented. The results show that the majority of mothers consulting the clinic perceive their lactation problems as 'insufficient breast milk production'. Factors which might have contributed to earl...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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abstract::Congenital anomalies exist all over the world. The management and outcome, however, vary considerably between the developed and the developing countries. This study looks at the impediments to the management of surgically correctable anomalies in South-east Nigeria. A prospective study was undertaken on 223 children w...
journal_title:Journal of tropical pediatrics
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abstract::India has recently completed 2 years without single case of poliomyelitis on 13 January 2013. This has brought South East Asian Region closer to eradication. Recently, India is being regarded as a role model for polio eradication efforts in other low-income endemic countries-Pakistan, Nigeria and Afghanistan. However,...
journal_title:Journal of tropical pediatrics
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abstract::We reported the case of a boy who fled from Chechnya to Belgium. He was diagnosed with a human immune deficiency virus (HIV)/Visceral leishmaniasis (VL) coinfection. In both countries, the prevalence of HIV-infected children is low and VL is not endemic. Migration of people results in confrontation with diseases that ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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abstract::A community-based study was undertaken to determine the prevalence and types of intestinal parasites in the pediatric population of Al-Baha region, Saudi Arabia. Stool samples were randomly collected from 19,939 children of whom 4208 (21.1%) were found to harbour intestinal parasites. The most affected age group was 5...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/41.1.47
更新日期:1995-02-01 00:00:00
abstract::Healthy children contacts of leprosy patients had their humoral and cell-mediated immunological status assessed using the Fluorescent Leprosy Antibody Absorption Technique (FLA-ABS) and the Lepromin test, respectively. Subsequently, they were followed up for 2 1/2 years to study the development of overt disease. Two-h...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/37.6.310
更新日期:1991-12-01 00:00:00
abstract::HIV/AIDS is an infection characterized by immune cell dysfunction and subsequent immunodeficiency, as well as intestinal disorder. Probiotics are live microbial feed supplements that beneficially affect the host animal by improving intestinal microbial balance and promoting health benefits. The goals of this study wer...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
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更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of therapeutic hypothermia (TH) using gel packs in reducing mortality and morbidity in term neonates with HIE and study the associated problems with TH. METHODS:Hypoxic ischaemic encephalopathy babies were randomized into TH and control group. Babies in TH group were cooled for first...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
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更新日期:2012-10-01 00:00:00
abstract::This study evaluates the impact of a milk-based cornstarch porridge fortified with iron, in 4-year olds, compared with control on hemoglobin levels and anemia prevalence. This trial was a cluster-randomized, double-blind one, and used milk-based cornstarch porridge fortified with 10 mg elemental iron (FeSO(4)), daily,...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
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更新日期:2012-10-01 00:00:00
abstract::We have compared intravenous magnesium sulphate vs. inhaled nitric oxide in the therapy of moderate persistent pulmonary hypertension of the neonate. A retrospective collection of clinical data from 58 neonates was carried out in six neonatal intensive care units of Southern Italy sharing the same operational protocol...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:1999-10-01 00:00:00
abstract::Quantity as well as quality of survivals determine the performance of a neonatal centre. Our centre has succeeded in improving survival with low cost technology without compromising the quality. Neurodevelopmental handicap was low on a 1-year follow-up. No baby had retinopathy of prematurity or hearing deficit. Dropou...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/37.5.250
更新日期:1991-10-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/46.3.172
更新日期:2000-06-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmr102
更新日期:2012-10-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/42.6.342
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the importance of food supplementation as incentive in improving preantiretroviral therapy (pre-ART) adherence, and second its impact on health of HIV-infected children by a clinic-based observational study. METHODS:HIV-seropositive children aged between 2 and 12 years were followed-up sequential...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmr026
更新日期:2012-02-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/46.6.365
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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更新日期:2010-12-01 00:00:00
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journal_title:Journal of tropical pediatrics
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更新日期:2004-10-01 00:00:00
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journal_title:Journal of tropical pediatrics
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doi:10.1093/tropej/42.2.85
更新日期:1996-04-01 00:00:00
abstract::This study evaluated the influence of iron supplementation in pregnancy and breastfeeding on iron status of lactating women from a Brazilian Human Milk Bank. Blood and mature breast milk samples were collected from 145 women for assessment of iron status, as well as copper and zinc status. Haemoglobin, serum iron and ...
journal_title:Journal of tropical pediatrics
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更新日期:2013-04-01 00:00:00
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journal_title:Journal of tropical pediatrics
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doi:10.1093/tropej/40.6.351
更新日期:1994-12-01 00:00:00
abstract::The association between the clinical outcome of chloroquine treatment and mutations in the putative Plasmodium falciparum chloroquine resistance transporter (Pfcrt) gene at codon 76 and multidrug resistance gene 1 (Pf mdr1) at codon 86 were investigated among 406 children with uncomplicated malaria presenting at five ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:2007-02-01 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 信件
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更新日期:2014-06-01 00:00:00
abstract::This study aims to evaluate the prevalence and sociodemographic factors of anemia in children <36 months old in China. In this study, data of 24 235 children were investigated from 32 primary health care (PHC) facilities in 11 province-level regions. Pearson χ2-test and logistic regression model were used to estimate ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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更新日期:2017-02-01 00:00:00