Therapeutic hypothermia using gel packs for term neonates with hypoxic ischaemic encephalopathy in resource-limited settings: a randomized controlled trial.

Abstract:

OBJECTIVE:To evaluate the efficacy of therapeutic hypothermia (TH) using gel packs in reducing mortality and morbidity in term neonates with HIE and study the associated problems with TH. METHODS:Hypoxic ischaemic encephalopathy babies were randomized into TH and control group. Babies in TH group were cooled for first 72 h of birth using cloth covered cooling gel packs to maintain target rectal temperature of 33-34°C. Infants were followed up to 6 months and were assessed using Baroda Developmental Screening Test. RESULTS:There were no significant differences in baseline parameters. TH group showed significant reduction in the combined rate of death or developmental delay at 6 months of age by 21% (8.1% in the TH group vs. 29% in the control, RR 0.28, 95% CI: 0.11-0.70; p = 0.003). CONCLUSIONS:TH using gel packs reduces the risk of death or developmental delay at 6 months of age in infants with HIE.

journal_name

J Trop Pediatr

authors

Bharadwaj SK,Bhat BV

doi

10.1093/tropej/fms005

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

382-8

issue

5

eissn

0142-6338

issn

1465-3664

pii

fms005

journal_volume

58

pub_type

杂志文章,随机对照试验
  • Treatment of COVID-19 with Chloroquine: Implication for Malaria Chemotherapy Using ACTs in Disease Endemic Countries.

    abstract::Based on reports of parasite resistance and on World Health Organization recommendation, chloroquine was replaced with the artemisinin-based combination therapies (ACTs) as the first choice of drugs for the treatment of uncomplicated malaria. Disuse of chloroquine led to restoration of drug-sensitive parasite to some ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmaa089

    authors: Quashie NB,Duah-Quashie NO

    更新日期:2020-12-27 00:00:00

  • Breast feeding of infants between 0-6 months old in 20 provinces, municipalities and autonomous regions in the People's Republic of China. National Coordinating Working Group for Breastfeeding Surveillance.

    abstract::This investigation was designed as an overall study of breast feeding rates and corresponding influencing factors in urban and rural communities in the People's Republic of China. In all 95,578 infants between 0 and 6 months old who lived within 20 different provinces or autonomous regions were subjects for the study ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/35.6.277

    authors: Yun YP,Kang ZS,Ling LJ,Xin QC

    更新日期:1989-12-01 00:00:00

  • The echocardiographic findings in kwashiorkor.

    abstract::Echocardiography (ECHO), electrocardiography (ECG), and chest radiography (CXR) were performed in 44 children with kwashiorkor, and 44 age- and sex-matched controls. In patients with kwashiorkor, mean values obtained for end diastolic dimension (29.2 +/- 3.8 mm), end systolic dimension (20.9 +/- 2.8 mm), posterior ven...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/41.2.74

    authors: Olowonyo MT,Ogunkunle OO,Akinbami FO,Jaiyesimi F

    更新日期:1995-04-01 00:00:00

  • Causes of malnutrition in young children: Gilan, Iran.

    abstract::Causes of malnutrition were investigated in agricultural area of Gilan, Iran. Family food availability and adult food intakes were adequate, but intakes of young children were deficient, in all socioeconomic groups, reflected in growth deficits. Associated factors were: late introduction and small quantities of solid ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/36.4.165

    authors: Rabiee F,Geissler C

    更新日期:1990-08-01 00:00:00

  • Vitamin A status and nutritional intake of carotenoids of preschool children in Ijaye Orile community in Nigeria.

    abstract::This study was carried out to determine the vitamin A status and nutritional intake of carotenoids of 213 children between the ages of 6 months and 6 years in a rural community in Nigeria. There were 109 males and 104 females. A total of 57 (26.8 per cent) children were deficient in serum retinol levels (< 10 microg/d...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/49.1.42

    authors: Oso OO,Abiodun PO,Omotade OO,Oyewole D

    更新日期:2003-02-01 00:00:00

  • Euthermia in Stable Preterm Babies: 'Cocooning' for Warmth! - A Randomized Controlled Trial.

    abstract::Very preterm babies, after their initial need for rigorous supports, remain in intensive care units for maintaining euthermia. We compared proportion of 'hypothermia OR hyperthermia episodes(HHE)'; physiological instability events; and weight gain in stable preterm babies between 29 and 32 weeks nursed in Cocoon warme...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/tropej/fmz025

    authors: Vijayan S,Pournami F,Prabhakar J,Jain N

    更新日期:2020-02-01 00:00:00

  • Is presence of hypertension in obese children correlate with the criteria of metabolic syndrome?

    abstract::In this article, we will describe the presence of metabolic syndrome and its components in a group of hypertensive and obese adolescents. The study presented here was conducted on 20 patients (10 boys) presented with complaints of obesity and hypertension who were diagnosed as metabolic syndrome. In 20 patients who we...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmm057

    authors: Mir S,Tabel Y,Darcan S

    更新日期:2007-12-01 00:00:00

  • Circulating growth hormone (GH), insulin-like growth factor-I (IGF-I) and free thyroxine, GH response to clonidine provocation and CT scanning of the hypothalamic-pituitary area in children with sickle cell disease.

    abstract::Serum growth hormone (GH), cortisol, free thyroxine (FT4), thyroid-stimulating hormone (TSH), and insulin like growth factor I (IGF-I) concentrations were measured in 15 children with sickle cell disease (SCD) together with their heights < 5th percentile for age and gender, and in 15 healthy age-matched children who h...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/41.5.285

    authors: Soliman AT,Darwish A,Mohammed SH,Bassiony MR,el Banna N,Asfour M

    更新日期:1995-10-01 00:00:00

  • Age-related weight-for-height charts for south Iranian school children.

    abstract::Analysis of data from the Shiraz (Iran) growth study requires to take age into account when assessing weight-for-height of school children aged 6-12. A unified structure standard score method is used to construct age-related weight-for-height. Weight-for-height charts were drawn for each age-sex category of children. ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/41.3.181

    authors: Ayatollahi SM

    更新日期:1995-06-01 00:00:00

  • Assessment of cardiac functions in sickle cell anemia with Doppler myocardial performance index.

    abstract:BACKGROUND:The purpose of this study was to evaluate left and right ventricular functions by using the Doppler myocardial performance index (MPI), in children with sickle cell anemia (SCA). METHODS:We examined 32 patients with SCA and 30 age-matched healthy children. Echocardiography and Doppler examinations were comp...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmp094

    authors: Arslankoylu AE,Hallioglu O,Yilgor E,Duzovali O

    更新日期:2010-06-01 00:00:00

  • Topical Oil Application and Trans-Epidermal Water Loss in Preterm Very Low Birth Weight Infants-A Randomized Trial.

    abstract:OBJECTIVE:Topical emollient application reduces trans-epidermal water loss (TEWL) in preterm neonates. Coconut oil used traditionally for infant massage in India has not been evaluated for the same. PATIENTS AND METHODS:Very low birth weight (VLBW) neonates were randomized at 12 h of age to Oil (n = 37) or Control (n ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/tropej/fmv049

    authors: Nangia S,Paul VK,Deorari AK,Sreenivas V,Agarwal R,Chawla D

    更新日期:2015-12-01 00:00:00

  • Thrombocytopoenia as marker for HIV exposure in the neonate.

    abstract::Thrombocytopoenia is a well-described marker of human immunedeficiency virus type 1 (HIV) infection of children. After documenting thrombocytopoenia in a HIV-exposed neonate, who was subsequently shown not to be infected, we evaluated thrombocytopoenia (platelets < 150 x 10(9)/l) as a marker for HIV exposure in newbor...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/47.4.208

    authors: Roux W,Pieper C,Cotton M

    更新日期:2001-08-01 00:00:00

  • Facility-Based Newborn Deaths at a Referral Tertiary Hospital in North-Central Nigeria during the Sustainable Development Goal Era: A Retrospective Cohort Analysis.

    abstract:BACKGROUND:Nigeria has the largest number of global under-five deaths and almost half of these occur in the newborn period in an almost 50:50 ratio across hospital facilities and communities. We examine and describe risk factors for newborn mortality at a busy neonatal unit of a referral tertiary hospital in North-cent...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmaa126

    authors: Ogunkunle TO,Gabriel TY,Bello SO,Abdullahi Y,Bulus J,Ozhe SI,Imam A

    更新日期:2021-01-09 00:00:00

  • Bacteremia and malaria in Tanzanian children hospitalized for acute febrile illness.

    abstract::We recorded the reason for presentation to a rural hospital in an area endemic for malaria in 909 children between January 2006 and March 2009. Blood smears were examined for Plasmodium falciparum parasites, and blood spots dried on filter paper were prepared for 464 children. A PCR assay utilizing the stored blood sp...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmu069

    authors: Lundgren IS,Heltshe SL,Smith AL,Chibwana J,Fried MW,Duffy PE

    更新日期:2015-04-01 00:00:00

  • Effect of a school feeding programme on nutritional status and anaemia in an urban slum: a preliminary evaluation in Kenya.

    abstract::To reduce malnutrition and improve child survival, school feeding programmes have been established in many parts of Africa, although prevalence of child malnutrition and anaemia remains high, especially in urban slums. The objective of this study is to evaluate the effect of a school feeding programme in the slums of ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fms070

    authors: Neervoort F,von Rosenstiel I,Bongers K,Demetriades M,Shacola M,Wolffers I

    更新日期:2013-06-01 00:00:00

  • Xerophthalmia, vitamin A supplementation and morbidity in children.

    abstract::The relationship between ocular manifestation of vitamin A deficiency and children's anaemic/morbidity status as well as the efficacy of vitamin A prophylaxis in preventing these conditions was determined. The prevalence of xerophthalmia in morbid children with anaemia and history of worm infestation, measles, and dia...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/39.2.89

    authors: Gujral S,Abbi R,Gopaldas T

    更新日期:1993-04-01 00:00:00

  • Role of Vitamin-D Deficiency in Term Neonates with Late-Onset Sepsis: A Case-Control Study.

    abstract:OBJECTIVE:To find the relationship between vitamin-D levels and late-onset sepsis (LOS) in term neonates. METHODS:This case-control study was conducted in neonatal intensive care unit of a tertiary care teaching institution in central India. Full-term neonates with culture-proven LOS were taken as cases. Maternal and ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmz021

    authors: Agrawal A,Gupta A,Shrivastava J

    更新日期:2019-12-01 00:00:00

  • Giardia duodenalis and soil-transmitted helminths infections in children in São Tomé and Príncipe: do we think Giardia when addressing parasite control?

    abstract::Giardia duodenalis prevalence is commonly as high as soil-transmitted helminths (STH), nevertheless is not considered for large-scale chemotherapy through mass drug administration (MDA) due to its short incubation period and frequent reinfections, its control being associated to improving access to water and sanitatio...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmu078

    authors: Ferreira FS,Baptista-Fernandes T,Oliveira D,Rodrigues R,Neves E,Lima A,Garrido E,Afonso G,Zaky A,Telles de Freitas P,Atouguia J,Centeno-Lima S

    更新日期:2015-04-01 00:00:00

  • Caregivers' understanding of pediatric medication in central Malawi.

    abstract:OBJECTIVE:To investigate caregivers' understanding of prescriptions of antibiotics and antimalarials for children in Malawi. METHOD:A cross-sectional study using interviews with 513 caregivers was undertaken in three different medical settings in two districts in Malawi for their understanding of medication defined as...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmu057

    authors: Sasaki E,Kamiya Y

    更新日期:2015-02-01 00:00:00

  • Improved pediatric weighing device for use with portable hanging scales.

    abstract::Portable hanging scales are a common means of weighing young children. Weighing trousers used to suspend children from a hanging scale are uncomfortable and require insertion of the child's legs through the trousers. The 'weighing seat' holds the child in a more natural, comfortable, and secure position, thus increasi...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/46.2.117

    authors: Murãmoto ML

    更新日期:2000-04-01 00:00:00

  • A study of feeding patterns in young infants.

    abstract::With the aim of studying the feeding patterns in infants under 6 months of age, 451 mothers attending the children's clinic in two university hospitals in the north of Tehran were interviewed. All babies had been born in hospital and > 98 per cent had been breastfed during the first few hours of birth. The rate of ful...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/49.2.89

    authors: Shiva F,Nasiri M

    更新日期:2003-04-01 00:00:00

  • Pediatric Antiretroviral Therapeutic Drug Monitoring: A Five and a Half Year Experience from a South African Tertiary Hospital.

    abstract:INTRODUCTION:Antiretroviral therapeutic drug monitoring (TDM) is not routinely used in the management of human immunodeficiency virus, but may be useful in pediatric patients who are prone to altered pharmacokinetics. Data on the routine use of antiretroviral TDM in pediatrics are sparse especially data from sub-Sahara...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmz077

    authors: Engelbrecht AE,Wiesner L,Norman J,Rabie H,Decloedt EH

    更新日期:2020-08-01 00:00:00

  • Severe vitamin B12 deficiency in a breast fed infant with pancytopenia.

    abstract::We report the case of a 7-month-old breast fed infant who presented with a nose bleed and bruises. Investigation showed severe nutritional B12 deficiency anemia with a pancytopenia. It is important to take the nutritional history of both the infant and the mother for early prevention and treatment. ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmp039

    authors: Citak FE,Citak EC

    更新日期:2011-02-01 00:00:00

  • Cytomegalovirus infection in preterm triplets transmitted via breast milk.

    abstract::Cytomegalovirus (CMV) may transmit perinatally or from breast milk. The risk for development of symptomatic CMV disease in very-low-birth-weight premature infants after transmission from maternal breast milk is not clear. There are scarce data in the literature about congenital CMV infection in multiple pregnancies, b...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmt087

    authors: Demirel G,Celik IH,Canpolat FE,Dilmen U

    更新日期:2014-04-01 00:00:00

  • Clinical correlates of CT abnormality in generalized childhood epilepsy in India.

    abstract::The CT scan gives valuable insight into the aetiology of epilepsy. Studies done so far in India suggest that the causes are quite different from the West. CT scan has become available in larger cities in India, but is expensive. Information about clinical features that may 'predict' a CT abnormality would be useful to...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/43.4.199

    authors: Kumar R,Navjivan S,Kohli N,Sharma B

    更新日期:1997-08-01 00:00:00

  • A visual dosing aid for first-line pediatric antiretroviral treatment in resource-poor settings.

    abstract::The visual dosing aid (VDA) was developed to facilitate dosing calculations in response to children's; growth and weight during antiretroviral treatment. The theoretical accuracy of the VDA was assessed using anthropometric data from 55 children receiving care in the USA and 324 children in the Democratic Republic of ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmn095

    authors: Callens SF,Westreich D,Kitetele F,Lusiama J,Shabani N,Belhorn T,Colebunders R,Behets F,Van Rie A

    更新日期:2009-04-01 00:00:00

  • Effectiveness of phototherapy units in Cameroon.

    abstract::Neonatal hyperbilirubinemia continues to be a leading cause of morbidity and mortality in resource-limited countries. The aim of this study was to measure the effectiveness of existing phototherapy units at a local hospital in Cameroon using an irradiance meter. Phototherapy units (n = 4) in one newborn nursery in Cam...

    journal_title:Journal of tropical pediatrics

    pub_type: 信件

    doi:10.1093/tropej/fmt110

    authors: Satrom K,Slusher T,Satrom J

    更新日期:2014-06-01 00:00:00

  • Clinical spectrum of cerebral palsy in north India--an analysis of 1,000 cases.

    abstract::One thousand children with cerebral palsy (CP) were reviewed to study their clinical profile, etiological factors and associated problems. Spastic quadriplegia constituted the predominant group (61 per cent), followed by spastic diplegia (22 per cent). Dyskinetic CP was present in 7.8 per cent of the cases. Acquired C...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/48.3.162

    authors: Singhi PD,Ray M,Suri G

    更新日期:2002-06-01 00:00:00

  • Renal function in acute malaria in children.

    abstract::Tests for renal function were performed in 75 smear positive children with acute malaria together with 10 control children. Plasmodium vivax and Plasmodium falciparum accounted for 52 and 46 per cent cases, respectively. Renal impairment in the form of decreased endogenous creatine clearance (less than 65 ml/min/m2) w...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/35.6.291

    authors: Ahmad SH,Danish T,Faridi MM,Ahmad AJ,Fakhir S,Khan AS

    更新日期:1989-12-01 00:00:00

  • Etiological spectrum of localization-related epilepsies in childhood and the need for CT scan in children with partial seizures with no obvious causation--a study from south India.

    abstract::The etiological spectrum of 558 children (< 16 years) with partial seizures seen in a university hospital in south India, was analysed using syndromic classification proposed by the International League Against Epilepsy (ILAE). Partial seizures accounted for 57 per cent of childhood epilepsies. Idiopathic localization...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/46.4.202

    authors: Murthy JM,Yangala R

    更新日期:2000-08-01 00:00:00