Abstract:
OBJECTIVE:To evaluate the importance of food supplementation as incentive in improving preantiretroviral therapy (pre-ART) adherence, and second its impact on health of HIV-infected children by a clinic-based observational study. METHODS:HIV-seropositive children aged between 2 and 12 years were followed-up sequentially for 2 years without and with food supplementation, respectively, with monitoring of disease parameters. The outcome morbidity parameters were compared and correlated. RESULT:Study showed significant improvement in clinic adherence (r = 0.165, p = 0.027) along with increased mean clinic visit (6.65 ± 1.43 vs. 8.01 ± 1.52, p = 0.000) and mean CD4 count (p = 0.028) with incentive. Provision of incentive correlated well (Pearson's r = 0.345) with number of visits which in turn had strong correlation with weight gain (r = 0.548), episodes of AIDS-defining illnesses (r = -0.412), hospitalization (r = -0.279). CONCLUSION:Food incentive could enhance pre-ART phase clinic adherence that decreases disease-related morbidities, setting the stage for improved treatment and care of seropositive children in future.
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
Kundu CK,Samanta M,Sarkar M,Bhattacharyya S,Chatterjee Sdoi
10.1093/tropej/fmr026subject
Has Abstractpub_date
2012-02-01 00:00:00pages
31-7issue
1eissn
0142-6338issn
1465-3664pii
fmr026journal_volume
58pub_type
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abstract::Iodine deficiency disorders IDD are major public health problems in India, including West Bengal. Existing programme to control IDD needs to be continuously monitored through recommended methods and indicators. The objective of this study was to assess the prevalence of goitre, status of urinary iodine excretion UIE l...
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更新日期:1991-08-01 00:00:00
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journal_title:Journal of tropical pediatrics
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更新日期:2006-10-01 00:00:00
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journal_title:Journal of tropical pediatrics
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pub_type: 杂志文章,随机对照试验
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journal_title:Journal of tropical pediatrics
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更新日期:1999-02-01 00:00:00
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更新日期:2020-11-14 00:00:00
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
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abstract::Hunter syndrome (or Mucopolysaccharidosis type II, MPS II) is an X-linked recessive disorder due to the deficiency of the iduronate-2-sulfatase (IDS) enzyme, resulting in the accumulation of heparan and dermatan sulfates in the lysosomes. The heterogeneity of clinical phenotypes, ranging from mild-to-severe forms, is ...
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