Vitamin A deficiency and T-cell subpopulations in children with meningococcal disease.

Abstract:

:Although group A meningococcal disease is a major cause of child morbidity and mortality in sub-Saharan Africa, little is known about vitamin A status and T-cell subpopulations in affected children. A prospective study of vitamin A levels and T-cell subpopulations was conducted in 41 children hospitalized for meningococcal meningitis in Butare, Rwanda, during an epidemic from September through November, 1992. The mean age of cases was 3.6 +/- 2.7 years (range 0.5-16 years). The case-fatality rate was 20 per cent; 73 per cent of the children had serum vitamin A levels consistent with subclinical deficiency (< 0.7 mumol/l), and 27 per cent had levels consistent with severe deficiency (< 0.35 mumol/l). Mean CD4 per cent was higher and CD8 per cent was lower among children with meningitis compared with known reference populations. These results suggest that meningococcal disease is characterized by T-cell subpopulation alterations and vitamin A deficiency.

journal_name

J Trop Pediatr

authors

Semba RD,Bulterys M,Munyeshuli V,Gatsinzi T,Saah A,Chao A,Dushimimana A

doi

10.1093/tropej/42.5.287

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

287-90

issue

5

eissn

0142-6338

issn

1465-3664

journal_volume

42

pub_type

杂志文章
  • The echocardiographic findings in kwashiorkor.

    abstract::Echocardiography (ECHO), electrocardiography (ECG), and chest radiography (CXR) were performed in 44 children with kwashiorkor, and 44 age- and sex-matched controls. In patients with kwashiorkor, mean values obtained for end diastolic dimension (29.2 +/- 3.8 mm), end systolic dimension (20.9 +/- 2.8 mm), posterior ven...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/41.2.74

    authors: Olowonyo MT,Ogunkunle OO,Akinbami FO,Jaiyesimi F

    更新日期:1995-04-01 00:00:00

  • Angiopoietin-1 and endostatin levels in cord plasma predict the development of bronchopulmonary dysplasia in preterm infants.

    abstract:OBJECTIVE:To determine whether angiopoietin-1 and endostatin levels in the cord blood could predict the subsequent development of bronchopulmonary dysplasia (BPD) in preterm infants. PATIENTS AND METHODS:A total of 102 preterm (gestational age ≤ 32 weeks) infants (28 infants developed BPD and 74 had no BPD) were enrol...

    journal_title:Journal of tropical pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1093/tropej/fmq112

    authors: Mohamed WA,Niyazy WH,Mahfouz AA

    更新日期:2011-10-01 00:00:00

  • Role of HCV coinfection towards disease progression and survival in HIV-1 infected children: a follow-up study of 10 years.

    abstract::The present study was taken up to evaluate the pattern of disease progression and survival in a group of HIV-1 positive children, coinfected with HCV infection (n=25) in comparison to those without such coinfection (n=23). There was a significant negative correlation between the rate of decline of the CD4 + T cell per...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmi103

    authors: Shivraj SO,Chattopadhya D,Grover G,Kumar A,Baveja UK

    更新日期:2006-06-01 00:00:00

  • Death in a diarrhoeal cohort of infants and young children soon after discharge from hospital: risk factors and causes by verbal autopsy.

    abstract::Assessing mortality pattern of children after discharge from hospital is important to guide appropriate management policy. We studied young children aged 1-23 months, who were discharged from an urban Diarrhoea Treatment Hospital. Children were enrolled on discharge from the hospital, and followed at home after 6 and ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/42.6.342

    authors: Islam MA,Rahman MM,Mahalanabis D,Rahman AK

    更新日期:1996-12-01 00:00:00

  • Procalcitonin: a marker of neonatal sepsis.

    abstract::This study was designed to assess the value of procalcitonin in establishing the diagnosis and evaluating the prognosis of neonatal sepsis. Thirty-four infants with neonatal sepsis were included in the study. Procalcitonin values of the cases with sepsis were (2.21 +/- 2.48 ng/ml) significantly higher than the values ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/48.1.10

    authors: Athhan F,Akagündüz B,Genel F,Bak M,Can D

    更新日期:2002-02-01 00:00:00

  • Idiopathic pulmonary haemosiderosis.

    abstract::Idiopathic pulmonary haemosiderosis (IPH) is a rare disorder characterized by recurrent bouts of haemoptysis, iron deficiency anaemia, and pulmonary infiltrates on chest radiograph. We present such a case and believe that it is the first report from the Middle East. ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/46.4.243

    authors: Paul G,Bhatnagar SK,al Maskary S,Kuruvilla S,Kurien S

    更新日期:2000-08-01 00:00:00

  • Weight, length, ponderal index, and intrauterine growth retardation in Brazil.

    abstract::The objective of this study was to classify intrauterine growth-retarded (IUGR) newborn babies from an urban region in Brazil into four different subtypes, according to their weight, length, and ponderal index (PI). Three hundred and fifty-six (356) babies were differentiated by this classification into IUGR subtypes ...

    journal_title:Journal of tropical pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1093/tropej/44.6.355

    authors: Rondó PH

    更新日期:1998-12-01 00:00:00

  • Analysis of Pathogen Distribution and Its Antimicrobial Resistance in Bloodstream Infections in Hospitalized Children in East China, 2015-2018.

    abstract::This study analyzed the pathogen distribution in bloodstream-infected (BSI) children hospitalized in Shandong Province from 2015 to 2018, to identify prevention strategies and select empiric antimicrobial therapy for BSI in children. Blood sample data from 14 107 children from 162 hospitals of Shandong Province were o...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmaa077

    authors: Wang C,Hao W,Yu R,Wang X,Zhang J,Wang B

    更新日期:2020-12-25 00:00:00

  • Assessment of chloroquine resistance of Plasmodium falciparum in children of Wad Medani (Central Sudan).

    abstract::The study reports on chloroquine resistance of Plasmodium falciparum among Sudanese children (6 month to 16 years) living at Wad Medani, Central Sudan. All RI-III levels of resistant response were confirmed, while in vitro sensitivity test indicated that 25 per cent of P. falciparum isolates examined had exhibited mat...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/38.4.162

    authors: Ibrahim AM,Ali FR,Ali ME

    更新日期:1992-08-01 00:00:00

  • Disseminated Cryptococcosis Presenting as Miliary Lung Shadows in an Immunocompetent Child.

    abstract::Disseminated cryptococcosis is infrequent in immunocompetent children. Pulmonary and central nervous system are the commonly involved sites of infection in an immunocompromised host. We report a fatal case of disseminated cryptococcosis in an immunocompetent host presenting as fever of unknown origin with miliary shad...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmx083

    authors: Ismail J,Chidambaram M,Sankar J,Agarwal S,Lodha R

    更新日期:2018-10-01 00:00:00

  • Identification of factors associated with the growth of schoolchildren in southern Iran.

    abstract::The effects of socio-economic/cultural factors on the growth of school children in the city of Shiraz (Southern Iran) are examined by using univariate and multivariate analysis (ANOVA and MANOVA). Districts of residence and fathers' level of education are identified as the factors affecting the growth of children afte...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/39.2.111

    authors: Ayatollahi SM

    更新日期:1993-04-01 00:00:00

  • Severe Necrotizing Pneumonia in Children: A Challenge to Intensive Care Specialist.

    abstract:OBJECTIVE:Necrotizing pneumonia (NP) is recently recognized as a complication of pneumonia. The data on NP are scant from developing world and we aimed to describe the characteristic features of NP in our children. STUDY DESIGN:Single center retrospective cohort analysis. PATIENT SELECTION:Institutional database of c...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmaa027

    authors: Sharma PK,Vinayak N,Aggarwal GK,Srivastava RD,Aggarwal PK,Kushwaha AS

    更新日期:2020-12-01 00:00:00

  • Cell-mediated immune responses in malnourished host.

    abstract::One hundred children in the age group 6 months to 5 years were investigated for cell-mediated immune response in relation to their nutrition. The nutritional status was assessed by the Wellcome classification. The majority (54 per cent) of children had marasmus. Absolute lymphocyte count was found to be significantly ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/35.4.175

    authors: Fakhir S,Ahmad P,Faridi MA,Rattan A

    更新日期:1989-08-01 00:00:00

  • Ten days vs. 14 days antibiotic therapy in culture-proven neonatal sepsis.

    abstract:BACKGROUND:There are no evidence-based guidelines for the treatment of neonatal sepsis although standard text books recommend 14 days of antibiotics for blood culture-proven neonatal sepsis. OBJECTIVE:The present study compared the effectiveness of a 10-day course of antibiotic therapy with the conventional 14-day cou...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/tropej/fmq012

    authors: Gathwala G,Sindwani A,Singh J,Choudhry O,Chaudhary U

    更新日期:2010-12-01 00:00:00

  • Adenosine deaminase in childhood pulmonary tuberculosis: diagnostic value in serum.

    abstract::The diagnostic value of serum adenosine deaminase (ADA) activity was evaluated in childhood pulmonary tuberculosis. Serum ADA levels were measured in 20 children diagnosed with pulmonary tuberculosis (group 1) and 150 children (group 2) including 128 with tuberculosis infection (Mantoux test positive) and 22 healthy c...

    journal_title:Journal of tropical pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1093/tropej/45.4.245

    authors: Kuyucu N,Karakurt C,Bilaloğlu E,Karacan C,Teziç T

    更新日期:1999-08-01 00:00:00

  • Testicular Schistosomiasis Mimicking Malignancy in a Child: A Case Report.

    abstract::Schistosomiasis is an important communicable disease in the developing world. However, testicular schistosomiasis is an extremely rare condition. We report a case of testicular schistosomiasis mimicking testicular tumour in a 13 year old who presented with huge unilateral testicular mass. The dilemma encountered in th...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmv041

    authors: Ekenze SO,Modekwe VO,Nzegwu MA,Ekpemo SC,Ezomike UO

    更新日期:2015-08-01 00:00:00

  • Heated Humidified High-Flow Nasal Cannula vs. Nasal Continuous Positive Airway Pressure for Post-extubation Respiratory Support in Preterm Infants: A Randomized Controlled Trial.

    abstract:OBJECTIVE:The objective of this study was to compare the efficacy and safety of heated humidified high-flow nasal cannula (HHHFNC) and nasal continuous positive airway pressure (nCPAP) for prevention of extubation failure in preterm infants. METHODS:Preterm infants (gestation ≥28 weeks) were randomized to HHHFNC or nC...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmaa082

    authors: Yengkhom R,Suryawanshi P,Gupta B,Deshpande S

    更新日期:2020-11-11 00:00:00

  • Management of malnourished children with acute diarrhoea and sugar intolerance.

    abstract::A protocol of nutritional rehabilitation using fermented milk, vegetable oil, and castor sugar has been tested on 54 Senegalese children age 6-36 months admitted with acute diarrhoea and malnutrition. At time of admission, 39 per cent of children were dehydrated and 26 per cent had sugar intolerance. In the course of ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/35.6.281

    authors: Beau JP,Fontaine O,Garenne M

    更新日期:1989-12-01 00:00:00

  • Myocarditis Prevalence in Paediatric Dengue Infection: A Prospective Study in Tertiary Hospital in Yogyakarta, Indonesia.

    abstract::Awareness of cardiac involvement in dengue infection has potentially valuable management implications. To determine the prevalence of myocarditis in dengue severity, we conducted prospective study of paediatric dengue illness at Dr. Sardjito General Hospital, a tertiary hospital in Yogyakarta, Indonesia, from period o...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmz020

    authors: Buntubatu S,Prawirohartono EP,Arguni E

    更新日期:2019-12-01 00:00:00

  • Detecting malnutrition at age 6-12 months: international comparisons of arm circumference v. standard anthropometry.

    abstract::Growth faltering, which may herald protein-energy malnutrition (PEM) usually begins between ages 6 and 12 months. However, arm circumference (AC or MUAC) has mainly been used to screen for PEM between 12 and 60 months of age, when AC is age-independent. This study of 378 infants aged 6-12 months in Pakistan, Nepal, Si...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/38.5.240

    authors: Pust R,Johnson P,Lautenschlager J

    更新日期:1992-10-01 00:00:00

  • Prevalence and Outcome of Sepsis-induced Myocardial Dysfunction in Children with 'Sepsis' 'With' and 'Without Shock'-A Prospective Observational Study.

    abstract:Objective:To estimate the prevalence and effects of sepsis-induced myocardial dysfunction (SIMD) in children with septic shock. Methodology:Enrolled children with septic shock (n = 31) and sepsis (n = 30) underwent echocardiography and cardiac troponin-I (cTnI) estimation within first 3 h. SIMD was defined as presence...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmx105

    authors: Jain A,Sankar J,Anubhuti A,Yadav DK,Sankar MJ

    更新日期:2018-12-01 00:00:00

  • Early detection of leprosy in children.

    abstract::Healthy children contacts of leprosy patients had their humoral and cell-mediated immunological status assessed using the Fluorescent Leprosy Antibody Absorption Technique (FLA-ABS) and the Lepromin test, respectively. Subsequently, they were followed up for 2 1/2 years to study the development of overt disease. Two-h...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/37.6.310

    authors: Dayal R

    更新日期:1991-12-01 00:00:00

  • Biparietal diameter, fetal maturity, and body weight in rural Tanzanian newborns.

    abstract::The biparietal diameter (BPD) in 202 rural Tanzanian newborns was measured and correlated to maturity and body weight. The mean BPD at birth was 9.0 cm. The average body weight was 2642 g. Fetal maturity was determined by Petrussa score, serving as an estimate for gestational age. The mean gestational age of the 202 n...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/44.2.66

    authors: Gutknecht JH

    更新日期:1998-04-01 00:00:00

  • Seroepidemiology of rubella in Saudi Arabia.

    abstract::The seroepidemiology of infection due to rubella virus in Saudi Arabia was investigated in various age groups including unvaccinated children (newborn to 15 years of age) using a newer rubella antibody test system, the ELISA with maximum sensitivity and reliability. The assessment of the immune status indicated the lo...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/35.4.169

    authors: Hossain A

    更新日期:1989-08-01 00:00:00

  • Iron supplementation in pregnancy and breastfeeding and iron, copper and zinc status of lactating women from a human milk bank.

    abstract::This study evaluated the influence of iron supplementation in pregnancy and breastfeeding on iron status of lactating women from a Brazilian Human Milk Bank. Blood and mature breast milk samples were collected from 145 women for assessment of iron status, as well as copper and zinc status. Haemoglobin, serum iron and ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fms055

    authors: Mello-Neto J,Rondó PH,Oshiiwa M,Morgano MA,Zacari CZ,dos Santos ML

    更新日期:2013-04-01 00:00:00

  • Assessing the performance of nurses in the management of malaria patients in Tanzania.

    abstract:BACKGROUND:In Tanzania, nurses play an important role in the management of patients with malaria. The study was conducted to identify the current status of the performance of nurses in the management of malaria patients, in order to provide the baseline data before the training intervention. METHODS:The study was cond...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmq100

    authors: Kanamori S,Kohi TW,Nyamhanga T,Mkude S

    更新日期:2011-10-01 00:00:00

  • Thrombocytopoenia as marker for HIV exposure in the neonate.

    abstract::Thrombocytopoenia is a well-described marker of human immunedeficiency virus type 1 (HIV) infection of children. After documenting thrombocytopoenia in a HIV-exposed neonate, who was subsequently shown not to be infected, we evaluated thrombocytopoenia (platelets < 150 x 10(9)/l) as a marker for HIV exposure in newbor...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/47.4.208

    authors: Roux W,Pieper C,Cotton M

    更新日期:2001-08-01 00:00:00

  • Reduction in Rotavirus Disease and Sustained Predominance of G2P[4] Rotavirus Strain following Introduction of Rotavirus Vaccine in Recife, Brazil.

    abstract::Rotavirus vaccination was introduced in Brazil in March 2006. We describe the distribution of rotavirus genotypes in children with acute gastroenteritis in a hospital in Recife, Brazil, during pre- and post-vaccination periods. There was a 43.8% reduction in the proportion of diarrhea episodes due to rotavirus. Nevert...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmv006

    authors: Montenegro FM,Falbo AR,Germano EM,Correia NB,Souza Eda S,Nakagomi O,Nakagomi T,Cuevas LE,Cunliffe NA,Correia JB

    更新日期:2015-06-01 00:00:00

  • Kangaroo mother care: a randomized controlled trial on effectiveness of early kangaroo mother care for the low birthweight infants in Addis Ababa, Ethiopia.

    abstract::A randomized controlled trial was conducted over a 1-year period (November 2001-November 2002) in Addis Ababa to study the effectiveness of early Kangaroo mother care before stabilization of low birthweight infants as compared with the conventional method of care. There were 259 babies weighing less than 2000 g during...

    journal_title:Journal of tropical pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/tropej/fmh085

    authors: Worku B,Kassie A

    更新日期:2005-04-01 00:00:00

  • Post-neonatal Tetanus in a PICU of a Developing Economy: Intensive Care Needs, Outcome and Predictors of Mortality.

    abstract:Objectives:To evaluate pediatric intensive care unit (PICU) needs, outcome and predictors of mortality in post-neonatal tetanus. Materials and methods:Review of 30 consecutive post-neonatal tetanus cases aged 1 months to 12 years admitted to a PICU in north India over a period of 10 years (January 2006 to December 201...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmx020

    authors: Angurana SK,Jayashree M,Bansal A,Singhi S,Nallasamy K

    更新日期:2018-02-01 00:00:00