Abstract:
:The present study was taken up to evaluate the pattern of disease progression and survival in a group of HIV-1 positive children, coinfected with HCV infection (n=25) in comparison to those without such coinfection (n=23). There was a significant negative correlation between the rate of decline of the CD4 + T cell percentage and the duration of the AIDS-free interval in most (80.0 per cent) of the HCV seropositive children showing such decline (r=-0.588; p=0.005). The HCV seropositive children had twofold higher risk of progression to development of AIDS than HCV seronegatives (RR=2.51; 95 per cent CI:1.34-4.69; p=0.004). There was a significant negative correlation between the rate of decline of CD4 + T cell percentage and overall survival duration for HCV seropositive group (r=-0.609; p=0.003). Moreover, children coinfected with HCV had more than twofold higher risks of death than those without HCV (RR=2.39; 95 per cent CI:1.17-4.89; p<0.01). It appears that HCV infection may be an important contributor to the rapid disease progression and increase in mortality in HCV-HIV-1 coinfected children of thalassemia major.
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
Shivraj SO,Chattopadhya D,Grover G,Kumar A,Baveja UKdoi
10.1093/tropej/fmi103keywords:
subject
Has Abstractpub_date
2006-06-01 00:00:00pages
206-11issue
3eissn
0142-6338issn
1465-3664pii
fmi103journal_volume
52pub_type
杂志文章abstract:OBJECTIVE:To investigate causes of and contributors to newborn deaths in rural Haryana using a three delays audit approach. METHODS:The study was conducted in 28 villages under the rural field practice area of the Comprehensive Rural Health Services Project, All India Institute of Medical Sciences situated in Ballabga...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fms060
更新日期:2013-04-01 00:00:00
abstract::A review of case histories of mother-infant pairs who attended a lactation clinic between January and December, 1989 is presented. The results show that the majority of mothers consulting the clinic perceive their lactation problems as 'insufficient breast milk production'. Factors which might have contributed to earl...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/38.2.78
更新日期:1992-04-01 00:00:00
abstract::One hundred children in the age group 6 months to 5 years were investigated for cell-mediated immune response in relation to their nutrition. The nutritional status was assessed by the Wellcome classification. The majority (54 per cent) of children had marasmus. Absolute lymphocyte count was found to be significantly ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.4.175
更新日期:1989-08-01 00:00:00
abstract:BACKGROUND:Neonatal mortality continues to be a significant problem in the Indian setting, especially in very low birth weight (VLBW) neonates. Selenium (Se) has been shown to possess antioxidant properties, and some recent studies have shown a reduction in the sepsis-attributable neonatal mortality with its use. India...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmv096
更新日期:2016-06-01 00:00:00
abstract::Schistosomiasis is an important communicable disease in the developing world. However, testicular schistosomiasis is an extremely rare condition. We report a case of testicular schistosomiasis mimicking testicular tumour in a 13 year old who presented with huge unilateral testicular mass. The dilemma encountered in th...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmv041
更新日期:2015-08-01 00:00:00
abstract::The effects of iron deficiency anemia (IDA) on nerve conduction and efficiency of iron therapy were investigated by peripheral nerve-electrophysiological measurements. Eighteen children (10 boys, eight girls; mean age 31 +/- 1.3 months) with IDA and 12 healthy children (six boys, six girls; mean age 29 +/- 1.3 months)...
journal_title:Journal of tropical pediatrics
pub_type: 临床试验,杂志文章
doi:10.1093/tropej/48.4.204
更新日期:2002-08-01 00:00:00
abstract::Ninety-three females in the age group 14-18 years were randomly selected from three schools in Colombo. Their iron and nutritional status was assessed using clinical, anthropometric, haematological, and biochemical parameters. Haemoglobin levels less than 12 g/dl were seen in 3.7 per cent of adolescent females. Free e...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/36.6.316
更新日期:1990-12-01 00:00:00
abstract:BACKGROUND:Because of the different genetic backgrounds, living environments and economic conditions, the epidemiologic, clinical characteristics and risk factors for coronary artery abnormalities (CAAs) in the Chinese population may differ among different parts of China. METHODS:We did a retrospective study to explor...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmv077
更新日期:2016-04-01 00:00:00
abstract::Very preterm babies, after their initial need for rigorous supports, remain in intensive care units for maintaining euthermia. We compared proportion of 'hypothermia OR hyperthermia episodes(HHE)'; physiological instability events; and weight gain in stable preterm babies between 29 and 32 weeks nursed in Cocoon warme...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmz025
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:To evaluate vitamin D status of preterm and term low birthweight (LBW) and term normal birth weight (NBW; weight ≥ 2500 g) infants at birth and in early infancy. METHODS:We enrolled 220 LBW and 119 NBW infants along with their mothers. Blood samples of both infants and mothers were taken within 48 h of birth...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fms013
更新日期:2012-12-01 00:00:00
abstract::The care of very low birth weight (VLBW) neonates may impose an enormous burden on professional resources and finances of caregivers. This study seeks to evaluate the immediate cost of care of VLBW babies in a developing economy. Twenty-four hospital case records VLBW babies who survived till discharge over a 1 year p...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmn107
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate left and right ventricular functions by using the Doppler myocardial performance index (MPI), in children with sickle cell anemia (SCA). METHODS:We examined 32 patients with SCA and 30 age-matched healthy children. Echocardiography and Doppler examinations were comp...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmp094
更新日期:2010-06-01 00:00:00
abstract::Serum immunoglobulin E (IgE) and absolute eosinophil count (AEC) were assayed in 48 children with idiopathic nephrotic syndrome and 20 controls. The mean serum IgE (p < 0.001) and AEC (p < 0.05) were significantly raised in active nephrotic syndrome compared with controls. The mean values of IgE and AEC in nephrotic p...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/50.3.149
更新日期:2004-06-01 00:00:00
abstract::Japanese encephalitis virus is a common cause of encephalitis in Asian children; therefore, maintenance of immunity against Japanese encephalitis virus is essential. Although many countries recommend booster vaccination, some trials have concluded that administration of one or two vaccinations is sufficient. The curre...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmt043
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the importance of food supplementation as incentive in improving preantiretroviral therapy (pre-ART) adherence, and second its impact on health of HIV-infected children by a clinic-based observational study. METHODS:HIV-seropositive children aged between 2 and 12 years were followed-up sequential...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmr026
更新日期:2012-02-01 00:00:00
abstract::Cassia occidentalis toxicity is thought to be uncommon; however, several cases have been described with acute hepatomyoencephalopathy with a high-mortality rate. We report a previously healthy, 2-year-old girl who developed acute liver failure after fresh seed ingestion. Without a specific antidote, we decided to impl...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmaa087
更新日期:2020-11-23 00:00:00
abstract::Social factors influencing diarrhoea prevalence rates, in Saudi communities, were studied during 1991 taking statistically representative samples from the whole population. The factors included mother's age, child's age, birth order, parent's education, feeding pattern, and urban, rural, and regional residences. This ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/41.supplement_1.45
更新日期:1995-01-01 00:00:00
abstract::Lymphocyte subsets, activation markers and apoptosis were assessed in 20 HIV-exposed noninfected (ENI) children born to HIV-infected women who were or not exposed to antiretroviral (ARV) drugs during pregnancy and early infancy. ENI children and adolescents were aged 6-18 years and they were compared to 25 age-matched...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmq024
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:Necrotizing pneumonia (NP) is recently recognized as a complication of pneumonia. The data on NP are scant from developing world and we aimed to describe the characteristic features of NP in our children. STUDY DESIGN:Single center retrospective cohort analysis. PATIENT SELECTION:Institutional database of c...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmaa027
更新日期:2020-12-01 00:00:00
abstract::The seroepidemiology of infection due to rubella virus in Saudi Arabia was investigated in various age groups including unvaccinated children (newborn to 15 years of age) using a newer rubella antibody test system, the ELISA with maximum sensitivity and reliability. The assessment of the immune status indicated the lo...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.4.169
更新日期:1989-08-01 00:00:00
abstract:Background:The aim of the study was to assess the effect of early-onset neutropenia (EON) on the development of candidemia in premature infants and evaluate other risk factors. Materials and Methods:This prospective study was carried out in a neonatal intensive care unit of Cairo University Hospital. Fifty neutropenic...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmx029
更新日期:2018-02-01 00:00:00
abstract::Healthy children contacts of leprosy patients had their humoral and cell-mediated immunological status assessed using the Fluorescent Leprosy Antibody Absorption Technique (FLA-ABS) and the Lepromin test, respectively. Subsequently, they were followed up for 2 1/2 years to study the development of overt disease. Two-h...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/37.6.310
更新日期:1991-12-01 00:00:00
abstract::This study was undertaken with the aim of providing adequate calories for optimal growth in low birth weight (LBW) by fortifying human milk with medium chain triglycerides and sugar. Twenty-one LBW babies with birth weight between 1.0 and 1.75 kg and gestational age 28-36 weeks constituted the study material. They wer...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.2.77
更新日期:1989-04-01 00:00:00
abstract::Haemophilus influenzae type B (Hib) vaccine, pneumococcal conjugate vaccine (PCV) and rotavirus (RV) vaccine are available in the private market in India, but, except for Hib in eight states, are not included in India's Universal Immunization Program (UIP). Pediatricians were surveyed about administering non-UIP vacci...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmu012
更新日期:2014-08-01 00:00:00
abstract::The aim of this article is to investigate the prevalence of Glucose-6-phosphate dehydrogenase (G6PD) deficiency in neonatal hyperbilirubinemia and to compare the clinical presentation and course of G6PD-deficient and normal patients. This study included a total of 624 term neonates with indirect hyperbilirubinemia fro...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmi042
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To determine whether angiopoietin-1 and endostatin levels in the cord blood could predict the subsequent development of bronchopulmonary dysplasia (BPD) in preterm infants. PATIENTS AND METHODS:A total of 102 preterm (gestational age ≤ 32 weeks) infants (28 infants developed BPD and 74 had no BPD) were enrol...
journal_title:Journal of tropical pediatrics
pub_type: 临床试验,杂志文章
doi:10.1093/tropej/fmq112
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Results in neonatal screening programs aiming at detection of congenital adrenal hyperplasia (CAH) can only report elevated levels of 17-hydroxy-progesterone (17-OHP), without being able to differentiate presence or absence of salt loss. AIM:To predict presence or absence of salt loss in newborn infants wit...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmv078
更新日期:2016-04-01 00:00:00
abstract::Free radicals have been implicated in the pathogenesis of neonatal septicemia. The present study was planned to estimate the lipid peroxidation and antioxidant status in neonatal septicemia. The study was done to evaluate the lipid peroxidation and antioxidant status, both enzymatic and non-enzymatic in neonates with ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fml013
更新日期:2006-10-01 00:00:00
abstract::Cytomegalovirus (CMV) may transmit perinatally or from breast milk. The risk for development of symptomatic CMV disease in very-low-birth-weight premature infants after transmission from maternal breast milk is not clear. There are scarce data in the literature about congenital CMV infection in multiple pregnancies, b...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmt087
更新日期:2014-04-01 00:00:00
abstract::Based on reports of parasite resistance and on World Health Organization recommendation, chloroquine was replaced with the artemisinin-based combination therapies (ACTs) as the first choice of drugs for the treatment of uncomplicated malaria. Disuse of chloroquine led to restoration of drug-sensitive parasite to some ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmaa089
更新日期:2020-12-27 00:00:00