Abstract:
Background:The aim of the study was to assess the effect of early-onset neutropenia (EON) on the development of candidemia in premature infants and evaluate other risk factors. Materials and Methods:This prospective study was carried out in a neonatal intensive care unit of Cairo University Hospital. Fifty neutropenic premature infants were matched to 50 non-neutropenics. Subjects were then regrouped into candidemics and non-candidemics to study other risk factors such as central venous catheters, mechanical ventilation, parenteral nutrition, drugs as corticosteroids and others. Candidemia was assessed by Bactec and then seminested polymerase chain reaction for culture negatives. Results:Candidemia developed in 28 neutropenic preterms and in 8 non-neutropenics (odds ratio = 6.68, 95% confidence interval = 2.61-17.1, p <0.001). Risk factors for invasive fungal infection in univariate analysis included bacterial septicemia, mechanical ventilation, parenteral nutrition and steroid therapy. Independent predictors of candidemia in multivariate regression analysis included EON, mechanical ventilation and steroid therapy. Conclusion:EON is an independent risk factor for candidemia in premature infants.
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
Ramy N,Hashim M,Abou Hussein H,Sawires H,Gaafar M,El Maghraby Adoi
10.1093/tropej/fmx029subject
Has Abstractpub_date
2018-02-01 00:00:00pages
51-59issue
1eissn
0142-6338issn
1465-3664pii
3749648journal_volume
64pub_type
杂志文章abstract::The aim of this article is to investigate the prevalence of Glucose-6-phosphate dehydrogenase (G6PD) deficiency in neonatal hyperbilirubinemia and to compare the clinical presentation and course of G6PD-deficient and normal patients. This study included a total of 624 term neonates with indirect hyperbilirubinemia fro...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmi042
更新日期:2006-02-01 00:00:00
abstract::We assessed the sensitivity, specificity and likelihood ratio of a low cost liquid crystal strip thermometer (LCT) compared with axillary mercury thermometry for the detection of neonatal hypothermia in Nepal. The subjects were 76 healthy newborns in the government maternity hospital of Kathmandu, Nepal in winter. The...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/44.1.15
更新日期:1998-02-01 00:00:00
abstract::The knowledge, attitude, and practices regarding breastfeeding of 310 mothers in five rural communities in Toto Local Government in Nassarawa State, Nigeria were investigated using a questionnaire. One hundred and sixty-two (52.3 per cent) mothers were illiterate while 148 (47.7 per cent) had either primary or seconda...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/45.6.323
更新日期:1999-12-01 00:00:00
abstract::Thrombocytopoenia is a well-described marker of human immunedeficiency virus type 1 (HIV) infection of children. After documenting thrombocytopoenia in a HIV-exposed neonate, who was subsequently shown not to be infected, we evaluated thrombocytopoenia (platelets < 150 x 10(9)/l) as a marker for HIV exposure in newbor...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/47.4.208
更新日期:2001-08-01 00:00:00
abstract:OBJECTIVES:We sought to investigate the dynamics of Mycoplasma pneumoniae (Mp) RNA in hospitalized young children with community-acquired pneumonia (CAP) and to explore whether Mp RNA clearance differed for wheezy and non-wheezy group after the onset of azithromycin treatment. METHODS:We included hospitalized young ch...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmaa109
更新日期:2020-12-04 00:00:00
abstract::Cardiac complications of 32 children with scorpion envenomation, during a 1-year period from August 1990 to August 1991 were studied. Sixteen children (50 per cent) were diagnosed as having myocarditis; of these in four children the presentation was subclinical. ECG changes were seen in 63 per cent of children envenom...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/41.6.338
更新日期:1995-12-01 00:00:00
abstract::The values of erythrocyte protoporphyrin, ferritin and mean corpuscular volume (MCV) measurements in diagnosing iron deficiency anemia were investigated in 72 iron deficient and in 25 healthy control infants. Receiver operator curve, sensitivity and specificity of erythrocyte protoporphyrin, ferritin and mean corpuscu...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/46.6.323
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:To compare the effectiveness of two antibiotic regimens among neonates with late onset sepsis (LOS). METHODS:This randomized controlled trial conducted in a tertiary care teaching hospital, South India, included 90 babies with LOS. Detailed history, examination and appropriate investigations were done for al...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmt080
更新日期:2014-02-01 00:00:00
abstract::Validity of naked eye single tube red cell osmotic fragility test ('Nestroft') was evaluated on 253 individuals divided into two groups. The HbA2 values estimated in each child was taken as gold standard. Group I comprised of 93 individuals belonging to families in which at least one of the children was suffering from...
journal_title:Journal of tropical pediatrics
pub_type: 临床试验,杂志文章
doi:10.1093/tropej/43.6.363
更新日期:1997-12-01 00:00:00
abstract::Fasciolosis is a chronic parasitic disease caused by two species of liver trematodes, Fasciola hepatica and Fasciola gigantica, which infest ruminants and rarely humans. The disease is spread all over the world, but more common in Asia in areas with extensive livestock farming and can be imported cases in Europe and A...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmz043
更新日期:2020-04-01 00:00:00
abstract::The aim of this study was to identify the reasons for hospitalization associated with abortion and pregnancy termination among women attending the Maternity Unit of IMIP, Recife, Brazil. In a case-control study, 230 women who were hospitalized consecutively between August 1994 and June 1995 due to causes related to pr...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/45.1.31
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:Preterm constitutes a major part of neonatal mortality, particularly in India. Due to dermal immaturity, preterm neonates are susceptible to various complications like infection, hypothermia, etc. Emollient application is a traditional practice in our subcontinent. AIMS:To find out the efficacy of coconut o...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmz041
更新日期:2020-04-01 00:00:00
abstract::The present study was taken up to evaluate the pattern of disease progression and survival in a group of HIV-1 positive children, coinfected with HCV infection (n=25) in comparison to those without such coinfection (n=23). There was a significant negative correlation between the rate of decline of the CD4 + T cell per...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmi103
更新日期:2006-06-01 00:00:00
abstract:INTRODUCTION:Antiretroviral therapeutic drug monitoring (TDM) is not routinely used in the management of human immunodeficiency virus, but may be useful in pediatric patients who are prone to altered pharmacokinetics. Data on the routine use of antiretroviral TDM in pediatrics are sparse especially data from sub-Sahara...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmz077
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of bovine colostrum (BC) on the treatment of children with acute diarrhea attending the outpatient clinic. METHODS:This double-blind randomized controlled trial was conducted on 160 children with diarrhea; 80 cases were randomly treated with BC group and 80 cases randomly received pla...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmz029
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Neonatal mortality continues to be a significant problem in the Indian setting, especially in very low birth weight (VLBW) neonates. Selenium (Se) has been shown to possess antioxidant properties, and some recent studies have shown a reduction in the sepsis-attributable neonatal mortality with its use. India...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmv096
更新日期:2016-06-01 00:00:00
abstract::Lymphocyte subsets, activation markers and apoptosis were assessed in 20 HIV-exposed noninfected (ENI) children born to HIV-infected women who were or not exposed to antiretroviral (ARV) drugs during pregnancy and early infancy. ENI children and adolescents were aged 6-18 years and they were compared to 25 age-matched...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmq024
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Early data regarding the outcome of human immunodeficiency virus (HIV)-infected children in paediatric intensive care units (PICU) suggested mortality as high as 100%. Recent studies report mortality of 38%. Survival depends on the indication for admission. OBJECTIVES:To describe the prevalence, duration of...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmm036
更新日期:2007-08-01 00:00:00
abstract::Preliminary to the development a new program supporting perinatal HIV prevention, this assessment was conducted to evaluate Vietnam's national prevention of mother-to-child HIV transmission (PMTCT) program by estimating HIV prevalence among prenatal women and analyzing the healthcare system capacity to deliver service...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1093/tropej/fmm112
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Because of the different genetic backgrounds, living environments and economic conditions, the epidemiologic, clinical characteristics and risk factors for coronary artery abnormalities (CAAs) in the Chinese population may differ among different parts of China. METHODS:We did a retrospective study to explor...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmv077
更新日期:2016-04-01 00:00:00
abstract::Very preterm babies, after their initial need for rigorous supports, remain in intensive care units for maintaining euthermia. We compared proportion of 'hypothermia OR hyperthermia episodes(HHE)'; physiological instability events; and weight gain in stable preterm babies between 29 and 32 weeks nursed in Cocoon warme...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmz025
更新日期:2020-02-01 00:00:00
abstract::Abdominal pain-predominant functional gastrointestinal diseases (AP-FGD) are common in children and commonly attributed to exposure to child abuse. However, this relationship has not been studied in teenagers, and the main objective of the current study was to assess it. Teenagers were recruited from four randomly sel...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmu035
更新日期:2014-10-01 00:00:00
abstract::During a 4-year period, March 1989 to February 1993, 22 children with proven urinary tract infections (UTI) due to Pseudomonas aeruginosa were studied retrospectively. The infections were more common in males (59 per cent), with the highest number of cases 10 (46 per cent) occurring in the 1-4 year age group. Sixty-ei...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/44.5.315
更新日期:1998-10-01 00:00:00
abstract::Burkitt's lymphoma is the most common childhood cancer in Africa. Most prevalent in areas endemic for malaria, the disease, a malignant growth of lymphoid tissue, usually presents itself as a large tumour of the jaw. When first characterized in the 1950s, the lymphoma was thought to spread by some infectious agent. Su...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,评审
doi:10.1093/tropej/36.3.114
更新日期:1990-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the importance of food supplementation as incentive in improving preantiretroviral therapy (pre-ART) adherence, and second its impact on health of HIV-infected children by a clinic-based observational study. METHODS:HIV-seropositive children aged between 2 and 12 years were followed-up sequential...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmr026
更新日期:2012-02-01 00:00:00
abstract::Idiopathic pulmonary haemosiderosis (IPH) is a rare disorder characterized by recurrent bouts of haemoptysis, iron deficiency anaemia, and pulmonary infiltrates on chest radiograph. We present such a case and believe that it is the first report from the Middle East. ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/46.4.243
更新日期:2000-08-01 00:00:00
abstract::We evaluated the effects of high-dose intravenous immunoglobulin (IVIG) administration on various protein parameters, including inflammatory profiles, in children with Kawasaki disease (KD). Sixty-three children with KD were treated with IVIG at 2 g/kg over 12 h. Serial examinations of laboratory indices were performe...
journal_title:Journal of tropical pediatrics
pub_type: 临床试验,杂志文章
doi:10.1093/tropej/fmh087
更新日期:2005-04-01 00:00:00
abstract::The present study describes the use of a home-based antenatal card in a sample of 120 consecutive women who were giving birth at a large teaching hospital in the city of León, Nicaragua. Information was obtained by interviews with the women before leaving hospital and all data on their antenatal cards and regarding de...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/40.3.133
更新日期:1994-06-01 00:00:00
abstract::A study of 128 jaundiced term neonates showed that 28 (22 per cent) had hearing loss based on brain stem-evoked response. There was no significant difference in the percentage of neonates with hearing loss between those with peak serum bilirubin levels of less than 340 mumol/l (16 per cent) and those with hyperbilirub...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/40.4.194
更新日期:1994-08-01 00:00:00
abstract::In an industrial hospital in India, a 23 per cent prevalence of low birth weight (LBW) was detected, of which 76 per cent were full term small for date (SFD) babies. Hypertensive disorders of pregnancy (HDP) comprised the single most common obstetrical problem associated with term SFD births (31 per cent). Age, parity...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/41.6.374
更新日期:1995-12-01 00:00:00