Procalcitonin: a marker of neonatal sepsis.

Abstract:

:This study was designed to assess the value of procalcitonin in establishing the diagnosis and evaluating the prognosis of neonatal sepsis. Thirty-four infants with neonatal sepsis were included in the study. Procalcitonin values of the cases with sepsis were (2.21 +/- 2.48 ng/ml) significantly higher than the values in the control group (0.71 +/- 0.5 ng/ml; p = 0.01). On the 7th day of therapy neonates who had achieved clinical recovery had a significant decrease of procalcitonin levels (0.55 +/- 0.27 ng/ml) compared to the initial values (p = 0.001). Initial mean procalcitonin levels of the cases resulting in death were 4.31 +/- 3.66 g/ml. This was significantly higher than the initial values of the patients who had clinical recovery (1.18 +/- 1.24 ng/ml;p = 0.02). Procalcitonin is a valuable marker for diagnosis, for evaluating prognosis and response to therapy in neonatal sepsis.

journal_name

J Trop Pediatr

authors

Athhan F,Akagündüz B,Genel F,Bak M,Can D

doi

10.1093/tropej/48.1.10

keywords:

subject

Has Abstract

pub_date

2002-02-01 00:00:00

pages

10-4

issue

1

eissn

0142-6338

issn

1465-3664

journal_volume

48

pub_type

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