Severe Multisystem Involvement of Chronic Granulomatous Disease in a Pediatric Patient.


:Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder identified by recurrent pyogenic and fungal infections infections secondary to defective nicotinamide adenine dinucleotide phosphate oxidase enzyme. In the present study, we demonstrated a case with a history of multiple segmental lung resections because of invasive bronchopulmonary aspergillosis, multifocal hepatic and splenic granulomas, bilateral adnexal calcific foci presumed to be related with old granulomatous infection and finally gastric outlet obstruction secondary to the involvement of the stomach wall thickening with granulomatous tissue. This is an extremely severe case of CGD with multiorgan involvement within a 10-year period after the diagnosis. Gastric antral involvement may mimic inflammatory bowel diseases in such cases, and intestinal involvement can reliably be demonstrated via ultrasonography. Spontaneous resolution of the antral involvement was observed in the follow-up.


J Trop Pediatr


Bayramoglu Z,Adaletli I,Caliskan E,Acar M,Hancerli Torun S,Somer A




Has Abstract


2019-04-01 00:00:00














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    journal_title:Journal of tropical pediatrics

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    authors: Paul G,Bhatnagar SK,al Maskary S,Kuruvilla S,Kurien S

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  • Assessment of drinking water fortification with iron plus ascorbic Acid or ascorbic Acid alone in daycare centers as a strategy to control iron-deficiency anemia and iron deficiency: a randomized blind clinical study.

    abstract:OBJECTIVE:Assess drinking water fortification with iron and/or ascorbic acid as a strategy to control iron-deficiency anemia and iron deficiency. METHODS:Randomized blind clinical study, fortifying drinking water to 153 pre-school children during 3 months, with iron and ascorbic acid (A), ascorbic acid (B) or plain wa...

    journal_title:Journal of tropical pediatrics

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    authors: de Almeida CA,De Mello ED,Ramos AP,João CA,João CR,Dutra-de-Oliveira JE

    更新日期:2014-02-01 00:00:00

  • Iron status of adolescent females in three schools in an urban area of Sri Lanka.

    abstract::Ninety-three females in the age group 14-18 years were randomly selected from three schools in Colombo. Their iron and nutritional status was assessed using clinical, anthropometric, haematological, and biochemical parameters. Haemoglobin levels less than 12 g/dl were seen in 3.7 per cent of adolescent females. Free e...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章


    authors: Atukorala TM,de Silva LD

    更新日期:1990-12-01 00:00:00

  • Unusual Clinical Manifestations and Outcome of Multisystem Inflammatory Syndrome in Children (MIS-C) in a Tertiary Care Hospital of North India.

    abstract::Till date, there is paucity of published literature on clinical manifestations of Coronavirus disease 2019 (COVID-19) in children from low-middle-income countries (LMIC). Most of the reports are from Europe, USA or China. Our study aimed to capture data on varied and unusual clinical presentation and management of MIS...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章


    authors: Gupta Dch S,Chopra Md N,Singh Md A,Gera R,Chellani Md H,Pandey PhD R,Arora Md BS

    更新日期:2021-01-29 00:00:00

  • High cost is the primary barrier reported by physicians who prescribe vaccines not included in India's Universal Immunization Program.

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    journal_title:Journal of tropical pediatrics

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    authors: Kahn GD,Thacker D,Nimbalkar S,Santosham M

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    abstract::With the aim of studying the feeding patterns in infants under 6 months of age, 451 mothers attending the children's clinic in two university hospitals in the north of Tehran were interviewed. All babies had been born in hospital and > 98 per cent had been breastfed during the first few hours of birth. The rate of ful...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章


    authors: Shiva F,Nasiri M

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    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章,随机对照试验


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    更新日期:2003-10-01 00:00:00

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    journal_title:Journal of tropical pediatrics

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  • Effect of a school feeding programme on nutritional status and anaemia in an urban slum: a preliminary evaluation in Kenya.

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    authors: Neervoort F,von Rosenstiel I,Bongers K,Demetriades M,Shacola M,Wolffers I

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  • Aspergillus fumigatus specific antibodies in multitransfused children with human immunodeficiency virus (HIV) infection in relation to serum levels of Interleukin-2, gamma Interferon and tumour necrosis factor.

    abstract::Anti-Aspergillus fumigatus antibodies (IgG and IgE class) and serum levels of cytokines (gamma Interferon, Interleukin-2 and tumour necrosis factor-alpha) were studied in multitransfused (MT) children in relation to human immunodeficiency virus (HIV) infection. The specific antibodies to Aspergillus fumigatus were pre...

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    pub_type: 杂志文章


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    journal_title:Journal of tropical pediatrics

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    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章


    authors: Todd CH,Sanders D

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    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章


    authors: Gallego-Marín C,Henao AC,Gómez-Marín JE

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    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章


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    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章


    authors: Hoque SS,Faruque AS,Mahalanabis D,Hasnat A

    更新日期:1994-12-01 00:00:00

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    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章,随机对照试验


    authors: Uslu S,Kumtepe S,Bulbul A,Comert S,Bolat F,Nuhoglu A

    更新日期:2011-08-01 00:00:00

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    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章


    authors: Ssenyonga R,Muwonge R,Nankya I

    更新日期:2004-12-01 00:00:00

  • Nutritional status, migration, mortality, and measles vaccine coverage during the 1983-1985 drought period: Timbuktu, Mali.

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    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章


    authors: Carnell MA,Guyon AB

    更新日期:1990-06-01 00:00:00