Severe Multisystem Involvement of Chronic Granulomatous Disease in a Pediatric Patient.

Abstract:

:Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder identified by recurrent pyogenic and fungal infections infections secondary to defective nicotinamide adenine dinucleotide phosphate oxidase enzyme. In the present study, we demonstrated a case with a history of multiple segmental lung resections because of invasive bronchopulmonary aspergillosis, multifocal hepatic and splenic granulomas, bilateral adnexal calcific foci presumed to be related with old granulomatous infection and finally gastric outlet obstruction secondary to the involvement of the stomach wall thickening with granulomatous tissue. This is an extremely severe case of CGD with multiorgan involvement within a 10-year period after the diagnosis. Gastric antral involvement may mimic inflammatory bowel diseases in such cases, and intestinal involvement can reliably be demonstrated via ultrasonography. Spontaneous resolution of the antral involvement was observed in the follow-up.

journal_name

J Trop Pediatr

authors

Bayramoglu Z,Adaletli I,Caliskan E,Acar M,Hancerli Torun S,Somer A

doi

10.1093/tropej/fmy022

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

192-195

issue

2

eissn

0142-6338

issn

1465-3664

pii

4993394

journal_volume

65

pub_type

杂志文章
  • Pattern of Congenital Anomalies in Newborn: A 4-Year Surveillance of Newborns Delivered in a Tertiary Healthcare Facility in the South-East Nigeria.

    abstract::Congenital abnormalities are important causes of morbidity and mortality in children and significantly add to the burdens on healthcare in developing countries. Unfortunately, there remains a paucity of information on congenital birth defects in most developing countries. This is a 4-year prospective study that assess...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmx067

    authors: Ekwochi U,Asinobi IN,Osuorah DCI,Ndu IK,Ifediora C,Amadi OF,Sunday Mba G

    更新日期:2018-08-01 00:00:00

  • Helicobacter pylori infection and recurrent abdominal pain in children.

    abstract::The association of Helicobacter pylori infection with recurrent abdominal pain (RAP) was studied in 65 children aged between 3 and 12 years. Cases with a specific cause for abdominal pain were excluded from the study. All the patients were subjected to upper gastrointestinal endoscopy and antral biopsy. The biopsy spe...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/49.4.250

    authors: Das BK,Kakkar S,Dixit VK,Kumar M,Nath G,Mishra OP

    更新日期:2003-08-01 00:00:00

  • Atypical kawasaki disease presenting with symptoms from the genitourinary system: an autopsy report.

    abstract::Symptoms from the genitourinary system are unusual in Kawasaki disease (KD). Renal involvement is even rarer and it is confirmed by biopsy when the person is alive. We describe the case of an 11-year-old boy admitted to the hospital complaining about prolonged fever (5 days) and hematuria. His urinalysis showed also p...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmn065

    authors: Papadodima SA,Sakelliadis EI,Goutas ND,Vlachodimitropoulos DG,Spiliopoulou CA

    更新日期:2009-02-01 00:00:00

  • Seroepidemiology of rubella in Saudi Arabia.

    abstract::The seroepidemiology of infection due to rubella virus in Saudi Arabia was investigated in various age groups including unvaccinated children (newborn to 15 years of age) using a newer rubella antibody test system, the ELISA with maximum sensitivity and reliability. The assessment of the immune status indicated the lo...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/35.4.169

    authors: Hossain A

    更新日期:1989-08-01 00:00:00

  • Treatment of COVID-19 with Chloroquine: Implication for Malaria Chemotherapy Using ACTs in Disease Endemic Countries.

    abstract::Based on reports of parasite resistance and on World Health Organization recommendation, chloroquine was replaced with the artemisinin-based combination therapies (ACTs) as the first choice of drugs for the treatment of uncomplicated malaria. Disuse of chloroquine led to restoration of drug-sensitive parasite to some ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmaa089

    authors: Quashie NB,Duah-Quashie NO

    更新日期:2020-12-27 00:00:00

  • Reduction in Rotavirus Disease and Sustained Predominance of G2P[4] Rotavirus Strain following Introduction of Rotavirus Vaccine in Recife, Brazil.

    abstract::Rotavirus vaccination was introduced in Brazil in March 2006. We describe the distribution of rotavirus genotypes in children with acute gastroenteritis in a hospital in Recife, Brazil, during pre- and post-vaccination periods. There was a 43.8% reduction in the proportion of diarrhea episodes due to rotavirus. Nevert...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmv006

    authors: Montenegro FM,Falbo AR,Germano EM,Correia NB,Souza Eda S,Nakagomi O,Nakagomi T,Cuevas LE,Cunliffe NA,Correia JB

    更新日期:2015-06-01 00:00:00

  • Improved pediatric weighing device for use with portable hanging scales.

    abstract::Portable hanging scales are a common means of weighing young children. Weighing trousers used to suspend children from a hanging scale are uncomfortable and require insertion of the child's legs through the trousers. The 'weighing seat' holds the child in a more natural, comfortable, and secure position, thus increasi...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/46.2.117

    authors: Murãmoto ML

    更新日期:2000-04-01 00:00:00

  • Prevention and early detection of leprosy in children.

    abstract::India with its 4 million cases of leprosy, accounts for one-third of the world's population of leprosy patients. One-fourth of them are below 15 years of age. We report a 5-year follow-up study of healthy children who were close contacts of leprosy patients, in order to: 1. detect subclinical infection and observe the...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/41.3.132

    authors: Dayal R,Bharadwaj VP

    更新日期:1995-06-01 00:00:00

  • Is a booster dose necessary in children after immunization with live attenuated Japanese encephalitis vaccine?

    abstract::Japanese encephalitis virus is a common cause of encephalitis in Asian children; therefore, maintenance of immunity against Japanese encephalitis virus is essential. Although many countries recommend booster vaccination, some trials have concluded that administration of one or two vaccinations is sufficient. The curre...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmt043

    authors: Choi UY,Lee SY,Kim KH,Kim DS,Choi KM,Cha SH,Kang JH

    更新日期:2013-10-01 00:00:00

  • Disseminated Cryptococcosis Presenting as Miliary Lung Shadows in an Immunocompetent Child.

    abstract::Disseminated cryptococcosis is infrequent in immunocompetent children. Pulmonary and central nervous system are the commonly involved sites of infection in an immunocompromised host. We report a fatal case of disseminated cryptococcosis in an immunocompetent host presenting as fever of unknown origin with miliary shad...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmx083

    authors: Ismail J,Chidambaram M,Sankar J,Agarwal S,Lodha R

    更新日期:2018-10-01 00:00:00

  • Characteristics of HIV infected adolescents in Latin America: results from the NISDI pediatric study.

    abstract:OBJECTIVE:HIV-infected adolescents are a heterogeneous population; source of infection, immunodeficiency severity and antiretroviral (ARV) experience vary. Here, we describe youth followed in an observational study at Latin American sites of the NICHD International Site Development Initiative (NISDI). METHODS:The NISD...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmq068

    authors: Santos Cruz ML,Freimanis Hance L,Korelitz J,Aguilar A,Byrne J,Serchuck LK,Hazra R,Worrell C,NISDI Pediatric Study Group 2010.

    更新日期:2011-06-01 00:00:00

  • Diarrhoea mortality in rural Bangladeshi children.

    abstract::Diarrhoeal mortality and hospital admissions for diarrhoea are described among children under the age of 5 years in a large rural Bangladeshi community during 1986-87. Acute watery (dehydrating) diarrhoea was associated with 11 per cent of all deaths among infants aged 1-11 months and 5 per cent among children aged 1-...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/37.1.31

    authors: Fauveau V,Yunus M,Zaman K,Chakraborty J,Sarder AM

    更新日期:1991-02-01 00:00:00

  • The epidemiological and clinical characteristics of diarrhea associated with enteropathogenic, enteroaggregative and diffuse-adherent Escherichia coli in Egyptian children.

    abstract::A total of 220 enteroadherent Escherichia coli were identified from 729 Egyptian children with diarrhea using the HEp-2 adherence assay. Enteropathogenic E.coli (EPEC = 38) was common among children <6 months old and provoked vomiting, while diffuse-adhering E.coli (DAEC = 109) induced diarrheal episodes of short dura...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmu034

    authors: Ahmed SF,Shaheen HI,Abdel-Messih IA,Mostafa M,Putnam SD,Kamal KA,Sayed AN,Frenck RW Jr,Sanders JW,Klena JD,Wierzba TF

    更新日期:2014-10-01 00:00:00

  • Acute suppurative parotitis in a 33-day-old patient.

    abstract::Acute suppurative parotitis is a rare disease in childhood. Its incidence is higher in premature newborns. Parotid swelling and pus drainage from Stenson's duct is pathognomonic, and Staphylococcus aureus is the causative agent in most cases. Here, a 33-day-old patient with acute suppurative parotitis is presented. ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmv012

    authors: Avcu G,Belet N,Karli A,Sensoy G

    更新日期:2015-06-01 00:00:00

  • Assessing the performance of nurses in the management of malaria patients in Tanzania.

    abstract:BACKGROUND:In Tanzania, nurses play an important role in the management of patients with malaria. The study was conducted to identify the current status of the performance of nurses in the management of malaria patients, in order to provide the baseline data before the training intervention. METHODS:The study was cond...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmq100

    authors: Kanamori S,Kohi TW,Nyamhanga T,Mkude S

    更新日期:2011-10-01 00:00:00

  • Aspergillus fumigatus specific antibodies in multitransfused children with human immunodeficiency virus (HIV) infection in relation to serum levels of Interleukin-2, gamma Interferon and tumour necrosis factor.

    abstract::Anti-Aspergillus fumigatus antibodies (IgG and IgE class) and serum levels of cytokines (gamma Interferon, Interleukin-2 and tumour necrosis factor-alpha) were studied in multitransfused (MT) children in relation to human immunodeficiency virus (HIV) infection. The specific antibodies to Aspergillus fumigatus were pre...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/42.2.85

    authors: Bhatnagar PK,Chattopadhya D,Sharma GL,Madan T,Sarma PU

    更新日期:1996-04-01 00:00:00

  • Hepatic dysfunction in childhood dengue infection.

    abstract::Hepatic functions of 61 children, diagnosed to have dengue infection (DI), aged 2 months to 12 years comprising 37 cases of dengue fever (DF), 16 with dengue hemorrhagic fever (DHF), and eight with dengue shock syndrome (DSS) were prospectively studied during the acute attack. Hepatomegaly (74 per cent), epistaxis (26...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/46.1.40

    authors: Mohan B,Patwari AK,Anand VK

    更新日期:2000-02-01 00:00:00

  • Immunological spectrum of childhood tuberculosis.

    abstract::Fifty-three children with tuberculous meningitis (TBM) were studied in parallel with 37 children with primary pulmonary complex (PPC), 32 tuberculin skin positive controls, and 38 skin negative controls for immunological evaluation. Proportions of peripheral blood total T and T helper lymphocytes (TH) were significant...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/38.1.31

    authors: Rajajee S,Narayanan PR

    更新日期:1992-02-01 00:00:00

  • CD4+ T-lymphocyte count/CD8+ T-lymphocyte count ratio: surrogate for HIV infection in infants?

    abstract:INTRODUCTION:Early diagnosis and treatment is necessary to prevent HIV-infected infants progressing to AIDS. Antibody testing is not confirmatory before the age of 18 months and PCR not widely available in resource-poor settings. We studied the accuracy of CD4(+) T-lymphocyte count, CD4% and CD4/CD8 ratio as surrogate ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmr102

    authors: Navaneethapandian PG,Karunaianantham R,Subramanyan S,Chinnayan P,Chandrasekaran P,Swaminathan S

    更新日期:2012-10-01 00:00:00

  • Comparison of two empiric antibiotic regimen in late onset neonatal sepsis--a randomized controlled trial.

    abstract:OBJECTIVE:To compare the effectiveness of two antibiotic regimens among neonates with late onset sepsis (LOS). METHODS:This randomized controlled trial conducted in a tertiary care teaching hospital, South India, included 90 babies with LOS. Detailed history, examination and appropriate investigations were done for al...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/tropej/fmt080

    authors: Ramasamy S,Biswal N,Bethou A,Mathai B

    更新日期:2014-02-01 00:00:00

  • The role of erythrocyte protoporphyrin in the diagnosis of iron deficiency anemia of children.

    abstract::The values of erythrocyte protoporphyrin, ferritin and mean corpuscular volume (MCV) measurements in diagnosing iron deficiency anemia were investigated in 72 iron deficient and in 25 healthy control infants. Receiver operator curve, sensitivity and specificity of erythrocyte protoporphyrin, ferritin and mean corpuscu...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/46.6.323

    authors: Serdar MA,Sarici SU,Kurt I,Alpay F,Okutan V,Kurnaz L,Kutluay T

    更新日期:2000-12-01 00:00:00

  • Xerophthalmia, vitamin A supplementation and morbidity in children.

    abstract::The relationship between ocular manifestation of vitamin A deficiency and children's anaemic/morbidity status as well as the efficacy of vitamin A prophylaxis in preventing these conditions was determined. The prevalence of xerophthalmia in morbid children with anaemia and history of worm infestation, measles, and dia...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/39.2.89

    authors: Gujral S,Abbi R,Gopaldas T

    更新日期:1993-04-01 00:00:00

  • Cell-mediated immune responses in malnourished host.

    abstract::One hundred children in the age group 6 months to 5 years were investigated for cell-mediated immune response in relation to their nutrition. The nutritional status was assessed by the Wellcome classification. The majority (54 per cent) of children had marasmus. Absolute lymphocyte count was found to be significantly ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/35.4.175

    authors: Fakhir S,Ahmad P,Faridi MA,Rattan A

    更新日期:1989-08-01 00:00:00

  • Assessment of Iodine Nutritional Status of School-Age Children in Kolkata District of West Bengal State in Post-Iodation Scenario.

    abstract::To evaluate the state of iodine nutrition in post-iodation scenario, 3500 children were examined clinically for endemic goitre. Iodine and thiocyanate were measured in 240 urine samples; iodine content in 210 salt samples was measured. Total goitre prevalence was 6.1%. Median urinary iodine level was 21.80 µg/dl, and ...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmy011

    authors: Bhattacharya U,Chandra AK

    更新日期:2019-02-01 00:00:00

  • Unusual Clinical Manifestations and Outcome of Multisystem Inflammatory Syndrome in Children (MIS-C) in a Tertiary Care Hospital of North India.

    abstract::Till date, there is paucity of published literature on clinical manifestations of Coronavirus disease 2019 (COVID-19) in children from low-middle-income countries (LMIC). Most of the reports are from Europe, USA or China. Our study aimed to capture data on varied and unusual clinical presentation and management of MIS...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmaa127

    authors: Gupta Dch S,Chopra Md N,Singh Md A,Gera R,Chellani Md H,Pandey PhD R,Arora Md BS

    更新日期:2021-01-29 00:00:00

  • Weight, length, ponderal index, and intrauterine growth retardation in Brazil.

    abstract::The objective of this study was to classify intrauterine growth-retarded (IUGR) newborn babies from an urban region in Brazil into four different subtypes, according to their weight, length, and ponderal index (PI). Three hundred and fifty-six (356) babies were differentiated by this classification into IUGR subtypes ...

    journal_title:Journal of tropical pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1093/tropej/44.6.355

    authors: Rondó PH

    更新日期:1998-12-01 00:00:00

  • Milk-based cornstarch porridge fortified with iron is effective in reducing anemia: a randomized, double-blind, placebo-controlled trial.

    abstract::This study evaluates the impact of a milk-based cornstarch porridge fortified with iron, in 4-year olds, compared with control on hemoglobin levels and anemia prevalence. This trial was a cluster-randomized, double-blind one, and used milk-based cornstarch porridge fortified with 10 mg elemental iron (FeSO(4)), daily,...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/tropej/fms003

    authors: Arcanjo FP,Arcanjo CC,Arcanjo FC,Campos Lde A,Amancio OM,Braga JA

    更新日期:2012-10-01 00:00:00

  • Safety and Ethics in Endoscopic Studies in Children: Evidence From the BEECH Study in Zambia.

    abstract:BACKGROUND:Environmental enteropathy is an example of a poorly-understood intestinal disorder affecting millions of children worldwide, characterized by malabsorption and stunting. Although there is increasing interest in non-invasive means of assessing intestinal structure and function, the potential value of intestin...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmaa074

    authors: Chandwe K,Amadi B,Chipunza M,Zyambo M,Kelly P

    更新日期:2020-11-14 00:00:00

  • Breastfeeding and weaning practices in Saudi Arabia.

    abstract::A National Child Health Survey was conducted during 1987 for which a stratified multi-stage sampling was done. Out of the 8482 mothers interviewed 6131 had at least one live birth 5 years or less before the survey. Eighty-two per cent of the currently breastfed children, were less than 6 months of age, but only 55 per...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/40.5.267

    authors: al-Mazrou YY,Aziz KM,Khalil M

    更新日期:1994-10-01 00:00:00

  • Case Series of Infantile Tremor Syndrome in Tertiary Care Paediatric Centre from Southern India.

    abstract:Introduction:Infantile tremor syndrome (ITS) is characterized by anaemia, skin depigmentation, tremors and developmental delay. The lack of sufficient literature on ITS and its conflicting association with vitamin B12 deficiency made us present this article. Objective:The objective of this study is to describe demogra...

    journal_title:Journal of tropical pediatrics

    pub_type: 杂志文章

    doi:10.1093/tropej/fmx062

    authors: Gowda VK,Kolli V,Benakappa A,Srinivasan VM,Shivappa SK,Benakappa N

    更新日期:2018-08-01 00:00:00