Abstract:
:Congenital abnormalities are important causes of morbidity and mortality in children and significantly add to the burdens on healthcare in developing countries. Unfortunately, there remains a paucity of information on congenital birth defects in most developing countries. This is a 4-year prospective study that assessed the patterns and predictors of congenital anomalies among newborns at the Enugu State University Teaching Hospital, Nigeria. In total, 5830 deliveries were recorded, of which 38 had congenital anomalies, giving an incidence rate of 6.5/1000 live births. Fifty-two newborns were enrolled as nested controls. Factors significantly associated with congenital anomalies were low birth weight (p = 0.009), low socio-economic class (p = 0.011), lower maternal educational attainment (p = 0.009), parity of ≥ 5 (p = 0.002), febrile illness (p = 0.001) and the use of local concoction in index pregnancy (p = 0.009). More than half of the anomalies reported involved the musculoskeletal system. Occurrence of congenital anomalies may be prevented by curtailing risk factors identified in this study.
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
Ekwochi U,Asinobi IN,Osuorah DCI,Ndu IK,Ifediora C,Amadi OF,Sunday Mba Gdoi
10.1093/tropej/fmx067subject
Has Abstractpub_date
2018-08-01 00:00:00pages
304-311issue
4eissn
0142-6338issn
1465-3664pii
4157890journal_volume
64pub_type
杂志文章abstract::Brucellar meningitis is relatively uncommon, especially in children younger than 1 year. We present another case of meningitis due to Brucella melitensis biotype 1 in a 11-month-old infant transmitted by breast milk. This is the first report of successful isolation of B. melitensis from the breast milk in the literatu...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmn017
更新日期:2008-08-01 00:00:00
abstract::Phenylketonruia (PKU) is an inherited metabolic disorder that results in progressive mental retardation. PKU is a paradigm of a disease that can be identified by proper screening of newborns and medical follow-up in order to prevent serious complications. The present study was designed to evaluate the Palestinian nati...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/50.2.101
更新日期:2004-04-01 00:00:00
abstract::The aim of the study was to determine the etiology of meningitis and sepsis in the newborn at the State University Hospital of Haiti and evaluate the susceptibility 'in vitro' of the pathogens to the antibiotics commonly used. This was a prospective case series study over a 10-month period (May 1997-February 1998) of ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/50.1.48
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to examine the uptake and predictors of monovalent human rotavirus and pneumococcal conjugate vaccines among children of age 12-35 months in Malawi. METHODS:This study used cross-sectional data obtained from the 2015-16 Malawi Demographic and Health Survey. Multivariate logisti...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmy050
更新日期:2019-06-01 00:00:00
abstract:Background:Heel prick is a frequent painful procedure in newborns. A lancet or a 26-gauge needle is used for a heel prick in India. Objective:To compare the pain caused by heel prick with a lancet or a 26-gauge needle in newborns admitted in the neonatal intensive care unit (NICU) using the preterm infant pain profile...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmw093
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Preterm constitutes a major part of neonatal mortality, particularly in India. Due to dermal immaturity, preterm neonates are susceptible to various complications like infection, hypothermia, etc. Emollient application is a traditional practice in our subcontinent. AIMS:To find out the efficacy of coconut o...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmz041
更新日期:2020-04-01 00:00:00
abstract::The study reports on chloroquine resistance of Plasmodium falciparum among Sudanese children (6 month to 16 years) living at Wad Medani, Central Sudan. All RI-III levels of resistant response were confirmed, while in vitro sensitivity test indicated that 25 per cent of P. falciparum isolates examined had exhibited mat...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/38.4.162
更新日期:1992-08-01 00:00:00
abstract::Liver involvement is commonly observed in patients with typhoid fever. However, a hepatitis-like picture with fever and jaundice is unusual and infrequently reported in the paediatric literature. Our aim was to characterize the clinical picture, biochemical features, and prognosis of typhoid hepatitis. One hundred cas...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/45.5.287
更新日期:1999-10-01 00:00:00
abstract:Objective:This study described the prevalence of IgG class antibodies against Toxocara spp. and their association with urticaria in 2- to 12-year-old children. Methods:This population-based cross-sectional study was conducted between May 2012 and September 2014. The study sample comprised 168 children. Blood samples w...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmw094
更新日期:2017-10-01 00:00:00
abstract::This study investigates the birthweight, gestational age, and body proportions of home births in a malarious area of Papua New Guinea. A population based cohort of pregnant women was followed longitudinally through pregnancy. Within the first few days of birth anthropometric measures were taken and a gestational age a...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/40.1.37
更新日期:1994-02-01 00:00:00
abstract:INTRODUCTION:Early diagnosis and treatment is necessary to prevent HIV-infected infants progressing to AIDS. Antibody testing is not confirmatory before the age of 18 months and PCR not widely available in resource-poor settings. We studied the accuracy of CD4(+) T-lymphocyte count, CD4% and CD4/CD8 ratio as surrogate ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmr102
更新日期:2012-10-01 00:00:00
abstract::To identify the immunization providers' characteristics associated with immunization rate in children younger than 2 years. A cohort and a cluster sampling design were implemented; 528 children between 18 and 70 months of age were sampled in five public health clinics in Mosul-Iraq. Providers' characterizations were o...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fms014
更新日期:2012-12-01 00:00:00
abstract::The aim of this study was to compare the neonatal outcomes of babies with birthweights < 10th centile to those with birthweights > or = 10th centile with a gestational age of 28-34 weeks. This retrospective hospital-based study was performed at a tertiary referral centre. All women with early, severe pre-eclampsia, ma...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/49.3.178
更新日期:2003-06-01 00:00:00
abstract::Diarrhoeal mortality and hospital admissions for diarrhoea are described among children under the age of 5 years in a large rural Bangladeshi community during 1986-87. Acute watery (dehydrating) diarrhoea was associated with 11 per cent of all deaths among infants aged 1-11 months and 5 per cent among children aged 1-...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/37.1.31
更新日期:1991-02-01 00:00:00
abstract::Based on reports of parasite resistance and on World Health Organization recommendation, chloroquine was replaced with the artemisinin-based combination therapies (ACTs) as the first choice of drugs for the treatment of uncomplicated malaria. Disuse of chloroquine led to restoration of drug-sensitive parasite to some ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmaa089
更新日期:2020-12-27 00:00:00
abstract::One-hundred-and-eighty-eight ostensibly normal, pubertal schoolchildren, aged 9-16 years, residing in Chinamora Communal Land, Zimbabwe, had blood taken to assess thyroid function. Total goitre rate in the area was 44 per cent in primary schoolchildren: 91 of the subjects tested were goitrous. Thyroid stimulating horm...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/37.4.199
更新日期:1991-08-01 00:00:00
abstract::Disseminated cryptococcosis is infrequent in immunocompetent children. Pulmonary and central nervous system are the commonly involved sites of infection in an immunocompromised host. We report a fatal case of disseminated cryptococcosis in an immunocompetent host presenting as fever of unknown origin with miliary shad...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmx083
更新日期:2018-10-01 00:00:00
abstract::Lysozyme level was measured in the fluid and serum of 42 tuberculous (25 pleural, 11 ascites and 6 pericardial) and 29 non-tuberculous (5 malignant, 9 empyema thoracis, 10 transudative ascites and 5 pyopericardium) effusions. The mean fluid lysozyme level was significantly raised in tuberculous pleural, ascites, and p...
journal_title:Journal of tropical pediatrics
pub_type: 临床试验,杂志文章
doi:10.1093/tropej/46.5.296
更新日期:2000-10-01 00:00:00
abstract::Giardia duodenalis prevalence is commonly as high as soil-transmitted helminths (STH), nevertheless is not considered for large-scale chemotherapy through mass drug administration (MDA) due to its short incubation period and frequent reinfections, its control being associated to improving access to water and sanitatio...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmu078
更新日期:2015-04-01 00:00:00
abstract::Mali was affected by the drought across the Sahel in 1983-1985. The present study describes the demographic and nutritional status in the Timbuktu region in May 1985, and contributes to the little data available for Mali during this period; malnutrition rates are compared to two other drought affected areas in the Sah...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/36.3.109
更新日期:1990-06-01 00:00:00
abstract::Japanese encephalitis virus is a common cause of encephalitis in Asian children; therefore, maintenance of immunity against Japanese encephalitis virus is essential. Although many countries recommend booster vaccination, some trials have concluded that administration of one or two vaccinations is sufficient. The curre...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmt043
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:To determine the time to normalization of procalcitonin (PCT) levels and duration of antibiotics in neonatal sepsis. METHODS:A prospective observational study design was used. The participants included were neonates with sepsis. The primary outcome measure was time to normalization of PCT levels and duration...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmy053
更新日期:2019-08-01 00:00:00
abstract::This is a descriptive study of short-course chemotherapy in children with nodal tuberculosis at Port Moresby General Hospital (PMGH). Between 1 August 1989 and 31 December 1997 5248 children were started on TB treatment. In the retrospective study 427 children were treated for lymph node TB up to 31 December 1996. Of ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/47.3.160
更新日期:2001-06-01 00:00:00
abstract::Alpha thalassaemia frequently occurs in several of the Middle Eastern populations. This study was conducted on 26 sickle cell disease (SCD) patients from Yemen and 19 normal children (Hb AA) living in Riyadh, Saudi Arabia. Blood samples were extracted by venepuncture, and haematological and biochemical parameters were...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/45.6.370
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:Febrile seizures may contribute to epilepsy later in life, but data in sub-Saharan Africa are scarce. We, therefore, conducted a hospital-based study on clinical characteristics of children with febrile seizures. METHODS:Over 2 years, we screened all pediatric admissions of Haydom Lutheran Hospital, northern...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmt022
更新日期:2013-08-01 00:00:00
abstract::A hospital-based descriptive recall study was conducted to assess the relationship, if any, between breastfeeding practices and morbidity from respiratory and diarrhoeal diseases in infants. A total of 343 infants (285 admitted patients and 58 controls) were recruited. Clinical and sociodemographic data and details re...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/45.2.115
更新日期:1999-04-01 00:00:00
abstract:Background:Without early recognition and treatment, neonatal meningitis (NM) has a high mortality and morbidity. Although some neonates have features of NM, many do not. In many low-resource settings, the laboratory support to diagnose NM is not available, and bedside diagnostics are needed. Methods:This retrospective...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmy003
更新日期:2019-02-01 00:00:00
abstract::HIV/AIDS is an infection characterized by immune cell dysfunction and subsequent immunodeficiency, as well as intestinal disorder. Probiotics are live microbial feed supplements that beneficially affect the host animal by improving intestinal microbial balance and promoting health benefits. The goals of this study wer...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmm066
更新日期:2008-02-01 00:00:00
abstract::This study, which was carried out in the Jos Plateau in Nigeria, analysed the changes in growth and body composition that occurred among 17 male and 13 female Fulani children (aged 4-13 years) in the 7-month period which followed their displacement from their homes into a temporary camp due to ethnic/religious violenc...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/49.5.279
更新日期:2003-10-01 00:00:00
abstract:Objectives:To evaluate pediatric intensive care unit (PICU) needs, outcome and predictors of mortality in post-neonatal tetanus. Materials and methods:Review of 30 consecutive post-neonatal tetanus cases aged 1 months to 12 years admitted to a PICU in north India over a period of 10 years (January 2006 to December 201...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmx020
更新日期:2018-02-01 00:00:00