Abstract：
:India with its 4 million cases of leprosy, accounts for one-third of the world's population of leprosy patients. One-fourth of them are below 15 years of age. We report a 5-year follow-up study of healthy children who were close contacts of leprosy patients, in order to: 1. detect subclinical infection and observe the development of overt disease by using the Fluorescent Leprosy Antibody Absorption Technique (FLA-ABS) and the lepromin test which assess the humoral and cell-mediated immunity (CMI), respectively; 2. evaluate the efficacy of dapsone as a chemoprophylactic agent in the 'at risk' contacts. Four-hundred-and-fifty-five healthy contacts were studied. Majority of the contacts of multibacillary patients (303) were FLA-ABS positive (75 percent) and lepromin negative (55 percent) showing that although most of them had been infected, the lepromin status was negative (P < 0.01). On the other hand, the majority of the contacts of paucibacillary patients (152) were lepromin positive (57 percent) (P < 0.05). Furthermore, only 61 percent of contacts of paucibacillary patients were FLA-ABS positive as compared to 75 percent of contacts of multibacillary patients demonstrating that the former had been exposed to a lesser quantum of infection (P < 0.05). On the basis of results of FLA-ABS and lepromin tests, these 455 contacts were classified into four groups, viz. Group I comprising children who were FLA-ABS positive and lepromin positive; Group II, who were FLA-ABS positive and lepromin negative; Group III, who were FLA-ABS negative and lepromin positive; and Group IV who were FLA-ABS negative and lepromin negative.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
Dayal R,Bharadwaj VPdoi
10.1093/tropej/41.3.132subject
Has Abstractpub_date
1995-06-01 00:00:00pages
132-8issue
3eissn
0142-6338issn
1465-3664journal_volume
41pub_type
杂志文章abstract：AIM:To assess the clinical outcomes of a combined approach to the treatment of severe acute malnutrition in an area of high HIV prevalence using: (i) an initial inpatient phase, based on WHO guidelines and (ii) an outpatient recovery phase using ready-to-use therapeutic food. METHODS:An operational prospective cohort ...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmn029
更新日期：2008-12-01 00:00:00
abstract：Objectives:To evaluate pediatric intensive care unit (PICU) needs, outcome and predictors of mortality in post-neonatal tetanus. Materials and methods:Review of 30 consecutive post-neonatal tetanus cases aged 1 months to 12 years admitted to a PICU in north India over a period of 10 years (January 2006 to December 201...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmx020
更新日期：2018-02-01 00:00:00
abstract：Objective:To estimate the prevalence and effects of sepsis-induced myocardial dysfunction (SIMD) in children with septic shock. Methodology:Enrolled children with septic shock (n = 31) and sepsis (n = 30) underwent echocardiography and cardiac troponin-I (cTnI) estimation within first 3 h. SIMD was defined as presence...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmx105
更新日期：2018-12-01 00:00:00
abstract：:In an industrial hospital in India, a 23 per cent prevalence of low birth weight (LBW) was detected, of which 76 per cent were full term small for date (SFD) babies. Hypertensive disorders of pregnancy (HDP) comprised the single most common obstetrical problem associated with term SFD births (31 per cent). Age, parity...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/41.6.374
更新日期：1995-12-01 00:00:00
abstract：:In this study, 80 male and female sickle cell patients, aged 4-50 years, with mild (severity index, SI < 6) and severe (SI > or = 6) forms of the disease were investigated). The levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone, cortisol, growth hormone (GH), free thyroxine (T4), and...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/38.6.307
更新日期：1992-12-01 00:00:00
abstract：:The diagnostic value of serum adenosine deaminase (ADA) activity was evaluated in childhood pulmonary tuberculosis. Serum ADA levels were measured in 20 children diagnosed with pulmonary tuberculosis (group 1) and 150 children (group 2) including 128 with tuberculosis infection (Mantoux test positive) and 22 healthy c...
journal_title：Journal of tropical pediatrics
pub_type： 临床试验,杂志文章
doi：10.1093/tropej/45.4.245
更新日期：1999-08-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to evaluate left and right ventricular functions by using the Doppler myocardial performance index (MPI), in children with sickle cell anemia (SCA). METHODS:We examined 32 patients with SCA and 30 age-matched healthy children. Echocardiography and Doppler examinations were comp...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmp094
更新日期：2010-06-01 00:00:00
abstract：:Portable hanging scales are a common means of weighing young children. Weighing trousers used to suspend children from a hanging scale are uncomfortable and require insertion of the child's legs through the trousers. The 'weighing seat' holds the child in a more natural, comfortable, and secure position, thus increasi...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/46.2.117
更新日期：2000-04-01 00:00:00
abstract：:We report diagnosis, treatment and evolution of cases of ocular toxocariasis in specialized consultation in Quindío, Colombia. No cases were seen during the 2000-17 period, but five cases were confirmed from November 2017 to March 2019; two children resulted with definitive loss of vision on the affected eye. Studies ...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmaa096
更新日期：2020-12-13 00:00:00
abstract：:Acute suppurative parotitis is a rare disease in childhood. Its incidence is higher in premature newborns. Parotid swelling and pus drainage from Stenson's duct is pathognomonic, and Staphylococcus aureus is the causative agent in most cases. Here, a 33-day-old patient with acute suppurative parotitis is presented. ...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmv012
更新日期：2015-06-01 00:00:00
abstract：:Symptoms from the genitourinary system are unusual in Kawasaki disease (KD). Renal involvement is even rarer and it is confirmed by biopsy when the person is alive. We describe the case of an 11-year-old boy admitted to the hospital complaining about prolonged fever (5 days) and hematuria. His urinalysis showed also p...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmn065
更新日期：2009-02-01 00:00:00
abstract：:This study investigates the birthweight, gestational age, and body proportions of home births in a malarious area of Papua New Guinea. A population based cohort of pregnant women was followed longitudinally through pregnancy. Within the first few days of birth anthropometric measures were taken and a gestational age a...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/40.1.37
更新日期：1994-02-01 00:00:00
abstract：:Mali was affected by the drought across the Sahel in 1983-1985. The present study describes the demographic and nutritional status in the Timbuktu region in May 1985, and contributes to the little data available for Mali during this period; malnutrition rates are compared to two other drought affected areas in the Sah...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/36.3.109
更新日期：1990-06-01 00:00:00
abstract：Introduction:Infantile tremor syndrome (ITS) is characterized by anaemia, skin depigmentation, tremors and developmental delay. The lack of sufficient literature on ITS and its conflicting association with vitamin B12 deficiency made us present this article. Objective:The objective of this study is to describe demogra...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmx062
更新日期：2018-08-01 00:00:00
abstract：:Determination of lead, cadmium, nickel, chromium, manganese and copper levels in colostrum samples (n = 30), collected from middle-class mothers, was carried out by electrothermal atomic absorption spectrophotometer (ETAAS) with Zeeman effect background correction using a tungsten-palladium-citric acid chemical modifi...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/47.2.81
更新日期：2001-04-01 00:00:00
abstract：:The cornerstone of emergency management of sepsis is early, goal-directed therapy. The purpose of this study was to evaluate the effect of intraosseous (IO) vs. intravenous (IV) access for resuscitation of patients with septic shock admitted to pediatric intensive care unit. This prospective interventional randomized ...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1093/tropej/fmx061
更新日期：2018-04-01 00:00:00
abstract：:Analysis of data from the Shiraz (Iran) growth study requires to take age into account when assessing weight-for-height of school children aged 6-12. A unified structure standard score method is used to construct age-related weight-for-height. Weight-for-height charts were drawn for each age-sex category of children. ...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/41.3.181
更新日期：1995-06-01 00:00:00
abstract：OBJECTIVE:To determine the time to normalization of procalcitonin (PCT) levels and duration of antibiotics in neonatal sepsis. METHODS:A prospective observational study design was used. The participants included were neonates with sepsis. The primary outcome measure was time to normalization of PCT levels and duration...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmy053
更新日期：2019-08-01 00:00:00
abstract：:Assessing mortality pattern of children after discharge from hospital is important to guide appropriate management policy. We studied young children aged 1-23 months, who were discharged from an urban Diarrhoea Treatment Hospital. Children were enrolled on discharge from the hospital, and followed at home after 6 and ...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/42.6.342
更新日期：1996-12-01 00:00:00
abstract：:Our study showed that enteral administration of prophylactic probiotics in neonatal intensive care setup could significantly reduce morbidity due to necrotising enterocolitis in very low birth weight newborn. It also helps in establishing early full enteral feeding and reduces hospital stay. ...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1093/tropej/fmn091
更新日期：2009-04-01 00:00:00
abstract：:Serum growth hormone (GH), cortisol, free thyroxine (FT4), thyroid-stimulating hormone (TSH), and insulin like growth factor I (IGF-I) concentrations were measured in 15 children with sickle cell disease (SCD) together with their heights < 5th percentile for age and gender, and in 15 healthy age-matched children who h...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/41.5.285
更新日期：1995-10-01 00:00:00
abstract：:Eosinophilia is very common among rural poulation in Barabanki and neighbouring districts with no access to hygienic mode of stool disposition. Significant proportions of these children are suffering from anemia, undernutrition, anorexia, pain abdomen, cough and hence long term morbidity. This adds to the DALY of a de...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmw035
更新日期：2016-12-01 00:00:00
abstract：:This study, which was carried out in the Jos Plateau in Nigeria, analysed the changes in growth and body composition that occurred among 17 male and 13 female Fulani children (aged 4-13 years) in the 7-month period which followed their displacement from their homes into a temporary camp due to ethnic/religious violenc...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/49.5.279
更新日期：2003-10-01 00:00:00
abstract：:Although group A meningococcal disease is a major cause of child morbidity and mortality in sub-Saharan Africa, little is known about vitamin A status and T-cell subpopulations in affected children. A prospective study of vitamin A levels and T-cell subpopulations was conducted in 41 children hospitalized for meningoc...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/42.5.287
更新日期：1996-10-01 00:00:00
abstract：:A total of 74 multitransfused (MT) children of beta thalassaemia major were analysed for prevalent viral markers transmitted through transfusion. A higher incidence of serological markers for Hepatitis B virus (HBV), cytomegalovirus (CMV) could be observed in the group of MT children compared to control group. There w...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/39.4.243
更新日期：1993-08-01 00:00:00
abstract：:This study attempts to select predictors for indirect estimation of low birth weight from three important anthropometric measurements (viz. body length, head and chest circumferences) taken at birth. The data of 422 Indian low birth weight babies have been used to select the best combination of predictors by examining...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/42.3.146
更新日期：1996-06-01 00:00:00
abstract：:Idiopathic pulmonary haemosiderosis (IPH) is a rare disorder characterized by recurrent bouts of haemoptysis, iron deficiency anaemia, and pulmonary infiltrates on chest radiograph. We present such a case and believe that it is the first report from the Middle East. ...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/46.4.243
更新日期：2000-08-01 00:00:00
abstract：:This study was carried out to examine the correlation between clinical diagnoses at the time of death and autopsy findings in newborn babies who died in the regional Neonatal Intensive Care Unit (NICU) of King Edward VII Memorial Hospital affiliated to Bombay University. A consecutive sample of 240 newborns that died ...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/47.5.295
更新日期：2001-10-01 00:00:00
abstract：:Fifty-three children with tuberculous meningitis (TBM) were studied in parallel with 37 children with primary pulmonary complex (PPC), 32 tuberculin skin positive controls, and 38 skin negative controls for immunological evaluation. Proportions of peripheral blood total T and T helper lymphocytes (TH) were significant...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/38.1.31
更新日期：1992-02-01 00:00:00
abstract：:The dietary adequacy (qualitative and quantitative) of preschool children residing in rural areas near Mysore (a district in south India) was assessed by the 'Food frequency method' and '24-h recall method'. Food intake assessed in three different seasons revealed that their diets were predominantly cereal based with ...
journal_title：Journal of tropical pediatrics
pub_type： 杂志文章
doi：10.1093/tropej/fmh072
更新日期：2005-02-01 00:00:00
