Abstract:
INTRODUCTION:In-hospital treatment of children with tuberculous meningitis (TBM) is not a feasible option in many resource-poor countries. Home-based treatment has shown to be a viable alternative. Adherence is an important factor determining success of treatment. OBJECTIVE:Identify possible barriers to adherence of home-based treatment and caretaker perception of the disease. METHOD:A qualitative study consisting of 11 in-depth semi-structured interviews was performed based on principles of the health belief model. RESULTS:Barriers of adherence identified include poor understanding of the disease and transmission route, difficulty with medication administration and side effects, lack of access to the health-care facility, long waiting times and hidden costs of transportation. Caretakers showed good appreciation of the adverse effects of noncompliance and benefits obtained from taking treatment in the home environment. CONCLUSION:Improved doctor-patient communication, information brochures, structural changes to hospital settings, provision of financial and peer support all contribute to optimal TBM home-based treatment.
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
van Elsland SL,Springer P,Steenhuis IH,van Toorn R,Schoeman JF,van Furth AMdoi
10.1093/tropej/fmr095subject
Has Abstractpub_date
2012-08-01 00:00:00pages
275-9issue
4eissn
0142-6338issn
1465-3664pii
fmr095journal_volume
58pub_type
杂志文章abstract::Neonatal hyperbilirubinemia continues to be a leading cause of morbidity and mortality in resource-limited countries. The aim of this study was to measure the effectiveness of existing phototherapy units at a local hospital in Cameroon using an irradiance meter. Phototherapy units (n = 4) in one newborn nursery in Cam...
journal_title:Journal of tropical pediatrics
pub_type: 信件
doi:10.1093/tropej/fmt110
更新日期:2014-06-01 00:00:00
abstract::Congenital malaria, defined as the presence of malaria parasites in the erythrocytes of newborns aged <7 days, was considered rare in endemic areas until recent studies started reporting high prevalence rates. Various theories have been postulated to explain this phenomenon, but they are not proven conclusively from r...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmn016
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:The aim of this study was to describe the clinical and epidemiological characteristics of pandemic influenza in hospitalized children. METHODS:A total of 114 patients with suspected H1N1 virus infection were hospitalized, and nasal swabs were sent to National Influenza Reference Laboratory for confirmation ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmq075
更新日期:2011-06-01 00:00:00
abstract::Mali was affected by the drought across the Sahel in 1983-1985. The present study describes the demographic and nutritional status in the Timbuktu region in May 1985, and contributes to the little data available for Mali during this period; malnutrition rates are compared to two other drought affected areas in the Sah...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/36.3.109
更新日期:1990-06-01 00:00:00
abstract::Validity of naked eye single tube red cell osmotic fragility test ('Nestroft') was evaluated on 253 individuals divided into two groups. The HbA2 values estimated in each child was taken as gold standard. Group I comprised of 93 individuals belonging to families in which at least one of the children was suffering from...
journal_title:Journal of tropical pediatrics
pub_type: 临床试验,杂志文章
doi:10.1093/tropej/43.6.363
更新日期:1997-12-01 00:00:00
abstract::Japanese encephalitis virus is a common cause of encephalitis in Asian children; therefore, maintenance of immunity against Japanese encephalitis virus is essential. Although many countries recommend booster vaccination, some trials have concluded that administration of one or two vaccinations is sufficient. The curre...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmt043
更新日期:2013-10-01 00:00:00
abstract::A total of 74 multitransfused (MT) children of beta thalassaemia major were analysed for prevalent viral markers transmitted through transfusion. A higher incidence of serological markers for Hepatitis B virus (HBV), cytomegalovirus (CMV) could be observed in the group of MT children compared to control group. There w...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/39.4.243
更新日期:1993-08-01 00:00:00
abstract:OBJECTIVE:Febrile seizures may contribute to epilepsy later in life, but data in sub-Saharan Africa are scarce. We, therefore, conducted a hospital-based study on clinical characteristics of children with febrile seizures. METHODS:Over 2 years, we screened all pediatric admissions of Haydom Lutheran Hospital, northern...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmt022
更新日期:2013-08-01 00:00:00
abstract::The present study describes the use of a home-based antenatal card in a sample of 120 consecutive women who were giving birth at a large teaching hospital in the city of León, Nicaragua. Information was obtained by interviews with the women before leaving hospital and all data on their antenatal cards and regarding de...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/40.3.133
更新日期:1994-06-01 00:00:00
abstract::Congenital Toxoplasma infection can only be discovered or prevented by the appropriate serological screening and subsequent treatment of the mother and her offspring. In Colombia, there is no obligatory Toxoplasma screening for pregnant women and both the reporting and follow-up of congenital toxoplasmosis cases is li...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmi072
更新日期:2006-04-01 00:00:00
abstract::We studied the age specific distribution of enteropathogens in young children presenting at a large diarrhoeal diseases hospital in urban Bangladesh. A 5 per cent systematic sample was used to examine 1207 rectal swab specimens of children aged 1-35 months with acute watery diarrhoea. Variation in isolation rates of e...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/40.6.351
更新日期:1994-12-01 00:00:00
abstract::The present study is aimed to describe the changes in the prevalence of symptoms of asthma, rhinitis and eczema among Brazilian adolescents (AD, 13-14 years old) between Phases 1 and 3 of the International Study of Asthma and Allergies in Childhood (ISAAC). The prevalence of self-reported symptoms of asthma, rhinitis ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fml044
更新日期:2007-02-01 00:00:00
abstract::The aim of this study was to compare the neonatal outcomes of babies with birthweights < 10th centile to those with birthweights > or = 10th centile with a gestational age of 28-34 weeks. This retrospective hospital-based study was performed at a tertiary referral centre. All women with early, severe pre-eclampsia, ma...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/49.3.178
更新日期:2003-06-01 00:00:00
abstract::To determine whether persistent rhinorrhoea constitutes a significant problem requiring intervention, 17 rural day care centres (Balwadis) in Tamilnadu, India, were visited. Among 414 children in the Balwadis 92 (22 per cent) children with persistent rhinorrhoea (15 days duration or longer) were identified. Demographi...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/46.6.365
更新日期:2000-12-01 00:00:00
abstract::The CT scan gives valuable insight into the aetiology of epilepsy. Studies done so far in India suggest that the causes are quite different from the West. CT scan has become available in larger cities in India, but is expensive. Information about clinical features that may 'predict' a CT abnormality would be useful to...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/43.4.199
更新日期:1997-08-01 00:00:00
abstract::India has recently completed 2 years without single case of poliomyelitis on 13 January 2013. This has brought South East Asian Region closer to eradication. Recently, India is being regarded as a role model for polio eradication efforts in other low-income endemic countries-Pakistan, Nigeria and Afghanistan. However,...
journal_title:Journal of tropical pediatrics
pub_type: 信件
doi:10.1093/tropej/fmt046
更新日期:2013-12-01 00:00:00
abstract::To evaluate the state of iodine nutrition in post-iodation scenario, 3500 children were examined clinically for endemic goitre. Iodine and thiocyanate were measured in 240 urine samples; iodine content in 210 salt samples was measured. Total goitre prevalence was 6.1%. Median urinary iodine level was 21.80 µg/dl, and ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmy011
更新日期:2019-02-01 00:00:00
abstract::A clinical assessment of gestational age using four different methods was performed in the same population of 358 Cameroonian newborn infants with the aim of determining the most applicable in the local context. Method applicability was compared in terms of validity, accuracy, reliability, and ease of administration. ...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/50.5.285
更新日期:2004-10-01 00:00:00
abstract::Missed opportunities and inappropriately time immunization substantially reduced the coverage achieved in Mozambique and Guinea Conakry. During coverage surveys in Mozambique, we noted dates of attendance at a health facility for growth monitoring or vaccination, and in Conakry we also abstracted dates of curative car...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/37.4.153
更新日期:1991-08-01 00:00:00
abstract::The seroepidemiology of infection due to rubella virus in Saudi Arabia was investigated in various age groups including unvaccinated children (newborn to 15 years of age) using a newer rubella antibody test system, the ELISA with maximum sensitivity and reliability. The assessment of the immune status indicated the lo...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.4.169
更新日期:1989-08-01 00:00:00
abstract::The aim of this article is to investigate the prevalence of Glucose-6-phosphate dehydrogenase (G6PD) deficiency in neonatal hyperbilirubinemia and to compare the clinical presentation and course of G6PD-deficient and normal patients. This study included a total of 624 term neonates with indirect hyperbilirubinemia fro...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmi042
更新日期:2006-02-01 00:00:00
abstract::A National Child Health Survey was conducted during 1987 for which a stratified multi-stage sampling was done. Out of the 8482 mothers interviewed 6131 had at least one live birth 5 years or less before the survey. Eighty-two per cent of the currently breastfed children, were less than 6 months of age, but only 55 per...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/40.5.267
更新日期:1994-10-01 00:00:00
abstract::Increased bilirubin formation and decreased bilirubin conjugation play an important role in the pathogenesis of the newborn jaundice. Although physiologic jaundice is seen in most of the newborns, there are many risk factors that affect the severity and duration of hyperbilirubinemia. The latest studies showed that th...
journal_title:Journal of tropical pediatrics
pub_type: 信件
doi:10.1093/tropej/fml067
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:The mother-to-child transmission of HIV, which accounts for 90% of infections in children, has been reduced markedly through the use of antiretroviral drugs by pregnant women and their newborns. Changes to the World Health Organization guidelines support further extension of the prevention of mother-to-child...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmv061
更新日期:2016-02-01 00:00:00
abstract::Of 511 young (1-19 years of age) Jamaicans sampled for IgG antibodies to Toxoplasma by the ELISA method, there was an overall prevalence of 45 per cent. Seropositivity ranged from 24-26 per cent in the 2-year-olds, up to 54 per cent in the 5-9-year-olds. There was no significant difference in prevalence between the se...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/35.5.234
更新日期:1989-10-01 00:00:00
abstract::This study was designed to examine the rates of HIV serostatus disclosure in a sample of HIV-infected children in the state of Karnataka in South India, their reactions to learning their HIV-positive status and the reasons for and barriers to disclosure from the point of view of their caregivers. We enrolled 233 HIV-i...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/fmx079
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Neonatal mortality continues to be a significant problem in the Indian setting, especially in very low birth weight (VLBW) neonates. Selenium (Se) has been shown to possess antioxidant properties, and some recent studies have shown a reduction in the sepsis-attributable neonatal mortality with its use. India...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fmv096
更新日期:2016-06-01 00:00:00
abstract::Diarrhoeal mortality and hospital admissions for diarrhoea are described among children under the age of 5 years in a large rural Bangladeshi community during 1986-87. Acute watery (dehydrating) diarrhoea was associated with 11 per cent of all deaths among infants aged 1-11 months and 5 per cent among children aged 1-...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/37.1.31
更新日期:1991-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of therapeutic hypothermia (TH) using gel packs in reducing mortality and morbidity in term neonates with HIE and study the associated problems with TH. METHODS:Hypoxic ischaemic encephalopathy babies were randomized into TH and control group. Babies in TH group were cooled for first...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1093/tropej/fms005
更新日期:2012-10-01 00:00:00
abstract::Healthy children contacts of leprosy patients had their humoral and cell-mediated immunological status assessed using the Fluorescent Leprosy Antibody Absorption Technique (FLA-ABS) and the Lepromin test, respectively. Subsequently, they were followed up for 2 1/2 years to study the development of overt disease. Two-h...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
doi:10.1093/tropej/37.6.310
更新日期:1991-12-01 00:00:00