Plasmid typing of Shigella sonnei epidemic strains and molecular relationship of their R-plasmids.

Abstract:

:We conducted a surveillance program on epidemic and/or endemic Shigella strains in Asturias (Spain), their frequency and dispersion in our community, and their R-plasmids. We analyzed initial isolates of Shigella sonnei from two epidemic outbreaks using antibiotic resistance patterns and plasmid profile analysis as epidemiological markers. We found that the 2 outbreaks were caused by different S. sonnei strains, which respectively carried one and two R-plasmids together with other plasmids. The molecular relationship among these and three other R-plasmids from two S. sonnei strains isolated during a previous outbreak, were studied by restriction enzyme analysis and DNA-DNA hybridizations. We were able to establish different levels of relationship among the six R-plasmids.

journal_name

Eur J Epidemiol

authors

Mendoza MC,Gonzalez AJ,Mendez FJ,Hardisson C

doi

10.1007/BF00144744

subject

Has Abstract

pub_date

1988-06-01 00:00:00

pages

158-63

issue

2

eissn

0393-2990

issn

1573-7284

journal_volume

4

pub_type

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