Rapid acquisition of polymorphic virulence markers during adaptation of highly pathogenic avian influenza H5N8 virus in the mouse.

abstract：:Since the 1990s the Mekong River delta has suffered a large decline in sediment supply causing coastal erosion, following catchment disturbance through hydropower dam construction and sand extraction. However, our new geological reconstruction of 2500-years of delta shoreline changes show that serious coastal erosion ...

journal_title：Scientific reports

authors： Tamura T,Nguyen VL,Ta TKO,Bateman MD,Gugliotta M,Anthony EJ,Nakashima R,Saito Y

更新日期：2020-05-15 00:00:00

abstract：:A unique combination of useful properties in boron-carbide, such as extreme hardness, excellent fracture toughness, a low density, a high melting point, thermoelectricity, semi-conducting behavior, catalytic activity and a remarkably good chemical stability, makes it an ideal material for a wide range of technological...

journal_title：Scientific reports

authors： Mondal S,Bykova E,Dey S,Ali SI,Dubrovinskaia N,Dubrovinsky L,Parakhonskiy G,van Smaalen S

更新日期：2016-01-18 00:00:00

abstract：:Fatty acid oxidation is the major energy pathway used by the kidney, although glycolysis becomes more important in the low oxygen environment of the medulla. Fatty acid oxidation appears to be reduced in renal fibrosis, and drugs that reverse this improve fibrosis. Expression of glycolytic genes is more variable, but ...

journal_title：Scientific reports

authors： Lee M,Harley G,Katerelos M,Gleich K,Sullivan MA,Laskowski A,Coughlan M,Fraser SA,Mount PF,Power DA

更新日期：2020-09-03 00:00:00

abstract：:Wheat (Triticum aestivum), one of the world's most important crops, is facing unprecedented challenges due to global warming. To evaluate the gene resources for heat adaptation in hexaploid wheat, small heat shock proteins (sHSPs), the key plant heat protection genes, were comprehensively analysed in wheat and related...

journal_title：Scientific reports

authors： Wang X,Wang R,Ma C,Shi X,Liu Z,Wang Z,Sun Q,Cao J,Xu S

更新日期：2017-05-31 00:00:00

abstract：:Urinary concentrations of the major progesterone (P4) metabolite pregnanediol-3-glucuronide (PDG) are used to confirm ovulation. We aimed to determine whether automated immunoassay of urinary P4 was as efficacious as PDG to confirm ovulation. Daily urine samples from 20 cycles in 14 healthy women in whom ovulation was...

journal_title：Scientific reports

authors： Gifford RM,Howie F,Wilson K,Johnston N,Todisco T,Crane M,Greeves JP,Skorupskaite K,Woods DR,Reynolds RM,Anderson RA

更新日期：2018-12-04 00:00:00

abstract：:Previous studies on the associations between dietary antioxidant vitamins and the risk of cervical cancer remain inconsistent, and little evidence is available for serum antioxidant vitamins, which provide more accurate measurements of these nutrients. We conducted a case-control study of 458 incident cases with invas...

journal_title：Scientific reports

authors： Guo L,Zhu H,Lin C,Che J,Tian X,Han S,Zhao H,Zhu Y,Mao D

更新日期：2015-09-04 00:00:00

abstract：:Antagonist pleiotropy, where a gene exerts a beneficial effect at early stages and a deleterious effect later on in an animal's life, may explain the evolutionary persistence of devastating genetic diseases such as Huntington's disease (HD). To date, however, there is little direct experimental evidence to support thi...

journal_title：Scientific reports

authors： Morton AJ,Skillings EA,Wood NI,Zheng Z

更新日期：2019-01-10 00:00:00

abstract：:Neurokinin B (NKB) is a hypothalamic neuropeptide binding preferentially to the neurokinin 3 receptor. Expression of the gene encoding NKB is elevated in postmenopausal women. Furthermore, rodent studies suggest that NKB signalling may mediate menopausal hot flushes. However, the effects of NKB administration on hot f...

journal_title：Scientific reports

authors： Jayasena CN,Comninos AN,Stefanopoulou E,Buckley A,Narayanaswamy S,Izzi-Engbeaya C,Abbara A,Ratnasabapathy R,Mogford J,Ng N,Sarang Z,Ghatei MA,Bloom SR,Hunter MS,Dhillo WS

更新日期：2015-02-16 00:00:00

abstract：:Ruthenium(II) complexes with 6-methyl-2-thiouracil cis-[Ru(6m2tu)2(PPh3)2] (1) and [Ru(6m2tu)2(dppb)] (2) (where PPh3 = triphenylphosphine; dppb = 1,4-bis(diphenylphosphino)butane; and 6m2tu = 6-methyl-2-thiouracil) are potent cytotoxic agents and able to bind DNA. The aim of this study was to evaluate in vitro cellul...

journal_title：Scientific reports

authors： Bomfim LM,de Araujo FA,Dias RB,Sales CBS,Rocha CAG,Correa RS,Soares MBP,Batista AA,Bezerra DP

更新日期：2019-08-07 00:00:00

abstract：:A panel of 32 candidate reference genes was used to identify the most stable genes for gene normalisation in quantitative RT-PCR studies using endometrial biopsies obtained from women with endometrial cancer (type 1 or type 2) and without cancer (controls). RNA from the biopsies was isolated, examined for purity and q...

journal_title：Scientific reports

authors： Ayakannu T,Taylor AH,Konje JC

更新日期：2020-05-21 00:00:00

abstract：:Natural and anthropogenic stressors can cause phase shifts from coral-dominated to algal-dominated states. In the Caribbean, over-fishing of large herbivorous fish and disease among the long-spined urchin, Diadema, have facilitated algal growth on degraded reefs. We found that diminutive species of urchin and parrotfi...

journal_title：Scientific reports

authors： Kuempel CD,Altieri AH

更新日期：2017-01-05 00:00:00

abstract：:Fire ants are widely studied, invasive and venomous arthropod pests. There is significant biomedical interest in immunotherapy against fire ant stings. However, mainly due to practical reasons, the physiological effects of envenomation has remained poorly characterized. The present study takes advantage of a recently-...

journal_title：Scientific reports

authors： Zamith-Miranda D,Fox EGP,Monteiro AP,Gama D,Poublan LE,de Araujo AF,Araujo MFC,Atella GC,Machado EA,Diaz BL

更新日期：2018-09-26 00:00:00

abstract：:Early treatment, soon after infection, reduces HIV transmissions and benefits patients. The Transmission Reduction Intervention Project (TRIP) evaluated a network intervention to detect individuals recently infected (in the past 6 months). TRIP was conducted in Greece (2013-2015) and focused on drug injector networks....

journal_title：Scientific reports

authors： Nikolopoulos GK,Pavlitina E,Muth SQ,Schneider J,Psichogiou M,Williams LD,Paraskevis D,Sypsa V,Magiorkinis G,Smyrnov P,Korobchuk A,Vasylyeva TI,Skaathun B,Malliori M,Kafetzopoulos E,Hatzakis A,Friedman SR

更新日期：2016-12-05 00:00:00

abstract：:Root hairs are tubular extensions of specific root epidermal cells important in plant nutrition and water absorption. To determine membrane glycerolipids in root hairs and roots may differ, as well as their respective response to nutrient availability, this study analyzed the membrane glycerolipid species in soybean r...

journal_title：Scientific reports

authors： Wei F,Fanella B,Guo L,Wang X

更新日期：2016-11-04 00:00:00

abstract：:Antigen-presenting cells including dendritic cells (DCs) express mannan receptors (MR) on their surface, which can be exploited in cancer therapy by designing immune-stimulatory viruses coated with mannan-modified capsids that then bind to DCs and initiate a potent immune response. Although the combination of anti-ang...

journal_title：Scientific reports

authors： Wang Y,Zhang J,Wu Y,Ding ZY,Luo XM,Liu J,Zhong WN,Deng GH,Xia XY,Deng YT,Wei YQ,Jiang Y

更新日期：2015-06-18 00:00:00

abstract：:Emergence of multiple drug resistant strains of pathogenic bacteria calls for new initiatives to combat infectious diseases. Gold nanoparticles (AuNPs), because of their non-toxic nature and size/shape dependent optical properties, offer interesting possibility. Here we report the antibacterial efficacy of AuNPs of di...

journal_title：Scientific reports

authors： Chatterjee T,Chatterjee BK,Chakrabarti P

更新日期：2017-08-29 00:00:00

abstract：:Magnetic vortex is one of the simplest topologically non-trivial textures in condensed matter physics. It is the ground state of submicron magnetic elements (dots) of different shapes: cylindrical, square etc. So far, the vast majority of the vortex dynamics studies were focused on thin dots with thickness 5-50 nm and...

journal_title：Scientific reports

authors： Guslienko KY,Kakazei GN,Ding J,Liu XM,Adeyeye AO

更新日期：2015-09-10 00:00:00

abstract：:Invasive plant species often form dense mono-dominant stands in areas they have invaded, while having only sparse distribution in their native ranges, and the reasons behind this phenomenon are a key point of research in invasive species biology. Differences in species composition between native and invasive ranges ma...

journal_title：Scientific reports

authors： Zheng Y,Liao Z

更新日期：2017-11-22 00:00:00

abstract：:Regarding the basics of ear structure-function relationships in fish, the actual motion of the solid otolith relative to the underlying sensory epithelium has rarely been investigated. Otolith motion has been characterized based on a few experimental studies and on approaches using mathematical modeling, which have yi...

journal_title：Scientific reports

authors： Schulz-Mirbach T,Olbinado M,Rack A,Mittone A,Bravin A,Melzer RR,Ladich F,Heß M

更新日期：2018-02-15 00:00:00

abstract：:Mild cognitive impairment (MCI) is a precursor phase of Alzheimer's disease (AD). As current treatments may be effective only at the early stages of AD, it is important to track MCI patients who will convert to AD. The aim of this study is to develop a high performance semi-mechanism based approach to predict the conv...

journal_title：Scientific reports

authors： Liu H,Zhou X,Jiang H,He H,Liu X,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2016-06-07 00:00:00

abstract：:Blockage of Delta-like 4 (DLL4)-directed Notch signaling induces excessive tip cell formation and endothelial proliferation resulting in dysfunctional angiogenesis in tumors. MMGZ01, as a murine anti-human DLL4 monoclonal antibody, specifically binds to human DLL4 and blocks Notch pathway. Here, the structure of MMGZ0...

journal_title：Scientific reports

authors： Jia X,Wang W,Xu Z,Wang S,Wang T,Wang M,Wu M

更新日期：2016-06-15 00:00:00

abstract：:Covert facial mimicry involves subtle facial muscle activation in observers when they perceive the facial emotional expressions of others. It remains uncertain whether prototypical facial features in emotional expressions are being covertly mimicked and also whether covert facial mimicry involves distinct facial muscl...

journal_title：Scientific reports

authors： Wingenbach TSH,Brosnan M,Pfaltz MC,Peyk P,Ashwin C

更新日期：2020-03-13 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Fernandes TFD,Saavedra-Villanueva O,Margeat E,Milhiet PE,Costa L

更新日期：2020-10-22 00:00:00

abstract：:Salinity is a critical abiotic stress, which significantly impacts the agricultural yield worldwide. Identification of the molecular mechanisms underlying the salt tolerance in euhalophyte Suaeda salsa is conducive to the development of salt-resistant crops. In the present study, high-throughput RNA sequencing was per...

journal_title：Scientific reports

authors： Zhang X,Yao Y,Li X,Zhang L,Fan S

更新日期：2020-03-06 00:00:00

abstract：:Geographic variation in aridity determines environmental productivity patterns, including large-scale variability in pathogens, vectors and associated diseases. If disease risk decreases with increasing aridity and is matched by immune defense, we predict a decrease in innate immune function along a gradient of increa...

journal_title：Scientific reports

authors： Nwaogu CJ,Cresswell W,Tieleman BI

更新日期：2020-04-03 00:00:00

abstract：:The threshold size for enlarged abdominal lymph nodes (E-ALNs), a common pediatric disorder, has yet to be standardized. According to the maximum short-axis diameter, this study divided ALNs into Grade A (≥ 10 mm), Grade B (8-10 mm), Grade C (5-8 mm), and Grade D (< 5 mm, normal). To identify the threshold size for E-...

journal_title：Scientific reports

authors： He L,Sun Y,Huang G

更新日期：2021-01-19 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) infection promotes a generalized activation of host responses that involves not only CD4 T cells, but also cells of the microenvironment, which are not directly infected, such as endothelial cells. The mechanisms triggering HIV-1-associated vascular alterations remain poorly...

journal_title：Scientific reports

authors： Balducci E,Leroyer AS,Lacroix R,Robert S,Todorova D,Simoncini S,Lyonnet L,Chareyre C,Zaegel-Faucher O,Micallef J,Poizot-Martin I,Roll P,Dignat-George F

更新日期：2019-07-16 00:00:00

abstract：:Optical antennas can be used to manipulate the direction and polarization of radiation from an emitter. Usually, these metallic nanostructures utilize localized plasmon resonances to generate highly directional and strongly polarized emission, which is determined predominantly by the antenna geometry alone, and is thu...

journal_title：Scientific reports

authors： Ghimire A,Shafran E,Gerton JM

更新日期：2014-09-24 00:00:00

abstract：:The SW Japan arc built by subduction of the Philippine Sea (PHS) plate exhibits uneven distribution of volcanoes: thirteen Quaternary composite volcanoes form in the western half of this arc, Kyushu Island, while only two in the eastern half, Chugoku district. Reconstruction of the PHS plate back to 14 Ma, together wi...

journal_title：Scientific reports

authors： Tatsumi Y,Suenaga N,Yoshioka S,Kaneko K,Matsumoto T

更新日期：2020-09-14 00:00:00

abstract：:A disposable cyclic voltammetry (CV) tag is printed on a plastic film by integrating wireless power transmitter, polarized triangle wave generator, electrochemical cell and signage through a scalable gravure printing method. By proximity of 13.56 MHz RF reader, the printed CV tag generates 320 mHz of triangular sweep ...

journal_title：Scientific reports

authors： Jung Y,Park H,Park JA,Noh J,Choi Y,Jung M,Jung K,Pyo M,Chen K,Javey A,Cho G

更新日期：2015-01-29 00:00:00